The MD Anderson Symptom Inventory (MDASI) is a multi-symptom patient-reported outcome (PRO) measure for clinical and research use. Use the MDASI to assess the severity of symptoms experienced by patients with cancer and the interference with daily living caused by these symptoms.
|MDASI Symptom Items||MDASI Interference Items|
|Nausea||Working (including housework)|
|Disturbed sleep||Relations with other people|
|Distress/feeling upset||Enjoyment of life|
|Shortness of breath||Mood|
|Lack of appetite|
The core MDASI’s 13 symptom items are those found to have the highest frequency and/or severity in patients with various cancers and treatment types. Disease site-specific and treatment-specific MDASI modules are available (sidebar, right).
The MDASI has several advantages over other symptom-assessment scales:
- It assesses both symptom severity and symptom interference with daily life
- It applies broadly across cancer types and treatments
- It can be adapted to specific cancer types, sites, and treatments (MDASI modules)
- Its 0-10 scale is easy for patients to understand and complete
- It is easily translated into other languages
The MDASI is available in paper-and-pencil, electronic, and telephone-based interactive voice response (IVR) formats, all of which are equally effective.
Order the MDASI
Individual and sets of symptom items from the MDASI Symptom Library may be added to the core MDASI or a MDASI module (sidebar, right) to create an experimental MDASI that is tailored to your clinical research or practice. Items are added to the end of the original questionnaire to maintain the integrity of its psychometric validity.
The MDASI Symptom Library items were derived from patient interviews and were cognitively debriefed. All symptom items are available in English, as well as in various languages.
Contact us to obtain permission to use any of the MDASI Symptom Library items to create a tailored questionnaire (REQUIRED). Our expert faculty can assist you with:
- Design of a customized MDASI that meets the needs of your study or practice;
- Available linguistically and psychometrically validated language translations of your selected items;
- Information about the sensitivity of particular items in specific populations.
Charges may apply for specialized services, depending on the scope of the request.
- Purpose: To assess the severity of multiple symptoms and the impact of symptoms on daily functioning
- Population: Patients with symptoms caused by cancer and cancer treatment
- Assessment areas: Severity of multiple symptoms and the impact of symptoms on daily functioning during the last 24 hours
- Method: Self-report, interview or via telephone-based interactive voice response (IVR) system
- Time required: Five minutes (less for electronic administration)
- Scoring: Please see the MDASI User's Guide
- Reliability: Cronbach alpha reliability ranges from 0.82 to 0.94
The MDASI is available in paper-and-pencil, electronic, and telephone-based interactive voice response (IVR) formats, all of which are equally effective. Electronic MDASI data capture offers several benefits:
- Allows symptoms to be monitored when the patient is away from the hospital
- Is convenient for patients, who may use their choice of web access, personalized patient portals, or smart phones to access questionnaires
- Minimizes missing data, especially in longitudinal studies
- Provides more accurate, real-time symptom data at expected time points
- The availability of immediate feedback could allow caregivers to address severe symptoms more effectively.
Click on a linked language to view a sample in PDF format.
Don't see a language you need? Contact us at firstname.lastname@example.org.
|Psychometrically and Linguistically Validated||Linguistically Validated|
In response to the FDA's 2009 guidance for the pharmaceutical industry on the use of PRO measures in medical product development to support labeling claims, we have prepared a MDASI User's Guide to document the development and psychometric properties of the MDASI and its modules. The User Guide addresses the recommendations in the FDA guidance and establishes the MDASI's adequacy as a measure to support medical product claims.
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Did You Know?
MDASI modules augment the 19 core MDASI symptom and interference items with additional symptoms that are unique to a particular patient population.
We are developing brief ‘fit-for-purpose’ patient-reported outcomes questionnaires that capture a patient's symptoms, their severity and their interference with functioning and quality of life.
Charles S. Cleeland, Ph.D.
Professor, Symptom Research