MDASI Chronic Myeloid Leukemia Module
The MD Anderson Symptom Inventory for chronic myeloid leukemia (MDASI-CML) is a site-specific MDASI module. Along with the core MDASI’s 13 symptom items and 6 interference items, the MDASI-CML also assesses 7 symptoms specific to chronic myeloid leukemia:
- diarrhea
- swelling
- rash/skin change
- muscle soreness/cramping
- bruising/bleeding easily
- malaise
- headache
Order the MDASI Chronic Myeloid Leukemia Module
Use our convenient online form to order the MDASI-CML for use in your clinical research, clinical practice, funded and non-funded academic research, commercial research, or reproduction in educational materials or other publications.
Every MDASI Module Contains...
All 13 MDASI core symptoms
pain, fatigue, nausea, disturbed sleep, distress, shortness of breath, difficulty remembering, lack of appetite, drowsiness, dry mouth, sadness, vomiting, numbness/tingling
All 6 MDASI interference items
general activity, mood, work, relations with others, walking, enjoyment of life
MDASI-CML Features
- Purpose: To assess the severity of multiple chronic myeloid leukemia-related symptoms and the impact of these symptoms on daily functioning
- Population: Patients with symptoms caused by chronic myeloid leukemia and its treatment
- Assessment areas: Severity of multiple symptoms and the impact of symptoms on daily functioning during the last 24 hours
- Method: Self-report; paper-and-pencil form or tablet PC (self-administered or via interview), or telephone-based interactive voice response (IVR) system
- Time required: Five minutes
- Scoring: Please see the MDASI User's Guide
- Reliability: Cronbach alpha reliability ranges from 0.91 to 0.94
MDASI-CML Language Versions
Click on a linked language to view a sample in PDF format.
Don't see a language you need? Contact us at symptomresearch@mdanderson.org.
| Psychometrically and Linguistically Validated | Linguistically Validated |
|---|---|
| English | Arabic Bulgarian Chinese - Simplified Czech Danish Dutch French German Greek Hebrew Hungarian Italian Korean Polish Portuguese - Portugal Russian Spanish Thai |
Selected MDASI-CML References
Validation
Williams LA, Garcia-Gonzalez A, Ault P, et al. A new symptom measure in chronic myeloid leukemia [abstract]. American Society of Clinical Oncology 47th Annual Meeting, Chicago IL, Jun 3-7, 2011. J Clin Oncol 29(15 Suppl), 2011; e19545.
Williams LA, Cortes JE, Ault P, Garcia-Gonzalez A, Williams JL, Cleeland CS. Including patient input in patient-reported outcome instrument development: examples from the MDASI-CML [abstract]. American Society of Hematology 2010 Annual Meeting, Orlando FL, Dec 4-7, 2010. Blood 116(21): 1065, 2010; 2573.
Cleeland CS, Mendoza TR, Wang XS, et al. Assessing Symptom Distress in Cancer: The M. D. Anderson Symptom Inventory. Cancer 89:1634-1646, 2000.
Clinical Application
Williams LA, Ault P, Garcia-Gonzalez A, et al. Relationship of patient-reported symptoms to daily functioning in chronic myeloid leukemia [abstract]. American Society of Hematology 54th Annual Meeting and Exposition, Atlanta GA, Dec 8-11, 2012. Blood 118(21): 2012; 4260.
Williams LA, Jacobsen PB, Sailors MH, et al. Symptoms in chronic myeloid leukemia survivors on tyrosine kinase inhibitor therapy at two cancer centers [abstract]. Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) 2012 International Symposium on Supportive Care in Cancer, New York NY, Jun 28-30, 2012. Support Care Cancer 20(Suppl 1): S240, 2012; 1003.
Garcia-Gonzalez A, Ault P, Williams LA, Williams JL, Cleeland CS, Cortes JE. Interactive voice response system compliance in chronic myeloid leukemia population [abstract]. American Society of Clinical Oncology 48th Annual Meeting, Chicago IL, Jun 1-5, 2012; e19589.
Williams LA, Ault PS, Garcia-Gonzalez A, et al. Identifying high symptom burden in patients with chronic myeloid leukemia on tyrosine kinase inhibitor therapy [abstract]. American Society of Hematology 53rd Annual Meeting and Exposition, San Diego CA, Dec 10-13, 2011. Blood 118(21): 1356, 2011; 3138.
Williams LA, Garcia-Gonzalez A, Ault P, et al. Symptom burden in patients with chronic myeloid leukemia (CML) on kinase inhibitor (KI) therapy [abstract]. American Society of Hematology 2010 Annual Meeting, Orlando FL, Dec 4-7, 2010. Blood 116(21): 1570-1571, 2010; 3838.
Williams LA, Ault P, Cleeland CS, et al. Symptom burden in chronic myeloid leukemia (CML) [abstract]. American Society of Clinical Oncology 2010 Annual Meeting, Chicago IL, Jun 4-8, 2010. J Clin Oncol 28(15 Suppl): 480s, 2010; 6133.