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Ovarian Cancer Treatment

When you're treated at MD Anderson for ovarian cancer, a team of some of the nation’s foremost experts customizes your care. This team of specialists communications and collaborates at every step. They customize your treatment to be sure you receive the highest chance for successful treatment with the least impact on your body.

Our physicians have extensive experience in treating every type of ovarian cancer, including rare ovarian cancers. We offer the latest, most-advanced therapies, including surgery, chemotherapy, hormonal therapies and targeted therapies.

Surgery usually is the first step in treating ovarian cancer. It is crucial that your surgeon be experienced in this delicate procedure. Studies have shown that patients with ovarian cancer have better outcomes and better chances for survival when the largest amount possible of the tumor is removed.

The gynecologic oncology surgeons at MD Anderson are some of the most experienced in the nation. This gives them a level of expertise that is available at few other cancer centers.

Pioneering Research

We’re constantly researching newer and more advanced ways to treat ovarian cancer, including working to understand it on the molecular and genetic level. In some cases, we can offer gene therapy and targeted therapies that are available at only a few places in the nation.

We are proud to house a prestigious federally funded ovarian cancer SPORE (Specialized Program of Research Excellence) program. This means we are able to offer a wide variety of clinical trials for new therapies.

Ovarian Cancer Treatments

If you are diagnosed with ovarian cancer, your doctor will discuss the best options to treat it. This depends on several factors, including:

  • The stage of the cancer
  • The size of the tumor after surgery (debulking)
  • Your desire to have children
  • Your age and overall health

One or more of the following therapies may be recommended to treat ovarian cancer or help relieve symptoms.


Surgery is the main treatment for ovarian cancer. Often, surgery is done to remove or biopsy a mass to find out if it is cancer. Once cancer is confirmed, the surgeon stages the cancer based on how far it has spread from the ovaries. If the disease seems to be limited to one or both ovaries, the surgeon will biopsy the pelvis and abdomen to find out if the cancer has spread.

Debulking: If it is obvious during the surgery that ovarian cancer has spread, the surgeon will remove as much of the tumor as possible. This may help other treatments work better.

The ovaries, uterus, cervix, Fallopian tubes and omentum (fatty tissue around these organs), and any other visible tumors in the pelvic and abdominal areas may be removed during debulking. The spleen, lymph nodes, liver or intestines also may be removed partially or completely. Sometimes debulking is not possible because the patient is not healthy enough or the tumor may be attached to other organs. In these cases, any tumor left will be treated with chemotherapy.


You may need chemotherapy after surgery to destroy ovarian cancer cells that are still in the body.

Intraperitoneal therapy (IP therapy) is a way to give chemotherapy drugs. It may be used if a small amount of tumor is left after debulking. Sometimes IP chemotherapy works better than regular chemotherapy. In IP treatment, concentrated chemotherapy is put into the abdominal cavity through a catheter (tiny tube) or implanted port. This allows it to come into contact with the cancer and the area of the body where the cancer is likely to spread. The drugs also get into the blood and travel through the body.

Radiation Therapy

Although radiation therapy rarely is used to treat ovarian cancer, it may help destroy any cancer cells that are left in the pelvic area. It also may be used if the cancer has come back after other treatments. In most cases, the main goal of radiation therapy is to control symptoms such as pain, not to treat the cancer.

Targeted Therapies

MD Anderson is among just a few cancer centers in the nation that are able to offer targeted therapies for some types of ovarian cancer. These new drugs stop the growth of cancer cells by interfering with certain proteins and receptors or blood vessels that supply the tumor with what it needs to grow.

Our Ovarian Cancer Clinical Trials
MD Anderson leads the nation in innovative research into the causes, prevention, detection and treatment of ovarian cancer. In fact, we are one of the few cancer centers in the nation to house a prestigious federally funded ovarian SPORE (Specialized Program of Research Excellence) program. This means we are able to offer a variety of clinical trials of new treatments for ovarian cancer.

Treatment at MD Anderson

Ovarian cancer is treated in our Gynecologic Oncology Center.

Clinical Trials

MD Anderson patients have access to clinical trials offering promising new treatments that cannot be found anywhere else.

Knowledge Center

Find the latest news and information about ovarian cancer in our Knowledge Center, including blog posts, articles, videos, news releases and more.


MD Anderson has licensed social workers to help patients and their loved ones cope with cancer.


Talk to someone who shares your cancer diagnosis and be matched with a survivor.

Prevention and Screening

Many cancers can be prevented with lifestyle changes and regular screening.