Immunotherapy Platform

Led by Sreyashi Basu, Ph.D., the Multi-Parametric Immune Monitoring team conducts high-dimensional immune profiling across single-cell, bulk and spatial transcriptomic modalities, integrated with functional immune assays and data-driven analyses to define interpretable immune states, spatial architectures and predictive biomarkers associated with treatment response and resistance.

Led by Sonali Jindal, M.D., the Spatial and Digital Pathology team drives clinical translation through a multi-modal pathology framework that leverages pathological review, immunohistochemistry and multiplex IF imaging to pair with transcriptomic insights for characterizing the spatial state of the tumor to define mechanisms of response and advance precision medicine.

Led by Alejandro Jimenez Sanchez, Ph.D., the Data Science team develops computational and machine learning frameworks for multimodal integration, statistical and systems-level modeling, predictive biomarker discovery and scalable translational analytics across single-cell, spatial, clinical and high-dimensional molecular datasets.