The Allison Institute’s scientific advisory board brings together global leaders in immunotherapy and immunobiology to provide strategic guidance and evaluation of the institute’s research portfolio and programs. The advisory board is co-chaired by Robert Schreiber, Ph.D., the Andrew M. and Jane M. Bursky Distinguished Professor of Pathology and Immunology at Washington University School of Medicine, and Elaine Mardis, Ph.D., co-executive director of the Steve and Cindy Rasmussen institute for Genomic Medicine at Nationwide Children’s Hospital and professor of Pediatrics at The Ohio State University College of Medicine.
Robert Schreiber, Ph.D.
Scientific Advisory Board Co-Chair
Robert Schreiber, Ph.D., is the Andrew M. and Jane M. Bursky
Distinguished Professor of Pathology and Immunology and director of
the Bursky Center for Human Immunology and Immunotherapy Programs at
Washington University School of Medicine in St. Louis, Missouri. He is
a tumor immunologist and cytokine biologist who has focused primarily
on interferon-gamma biology, seeking to understand the mechanisms
underlying natural and therapeutically induced immune responses to
developing and established cancers. Schreiber demonstrated that the
immune system can prevent tumor outgrowth, induce tumor dormancy and
sculpt tumor immunogenicity — a process he named cancer immunoediting.
Schreiber is a member of the National Academy of Sciences and the
American Academy of Arts and Sciences along with many other
Elaine Mardis, Ph.D.
Scientific Advisory Board Co-Chair
Elaine Mardis, Ph.D., is co-executive director of the Steve and Cindy Rasmussen Institute for Genomic Medicine at Nationwide Children’s Hospital in Columbus, Ohio, and holds the Rasmussen Nationwide Foundation Endowed Chair of Genomic Medicine. She also is professor of Pediatrics at The Ohio State University College of Medicine, a member of the National Academy of Medicine and past president of the American Association for Cancer Research. Mardis is an internationally recognized expert in cancer genomics and immunogenomics, with interests in the integrated characterization of cancer genomes, defining DNA-based interactions and RNA-based pathways and immune microenvironments that lead to cancer onset and progression, with a focus on pediatric cancers and precision oncology.
Mark Dawson, M.D., Ph.D.
Mark Dawson, M.D., Ph.D., is a clinician-scientist and an associate
director of the Peter MacCallum Cancer Centre in Melbourne, Australia.
He also is a professor at the University of Melbourne, the Sir Edward
Dunlop Fellow for the Cancer Council of Victoria and a Howard Hughes
Medical Institute International Research Scholar. Dawson’s research is
focused on studying epigenetic regulation in normal development and
cancer. His research has helped identify several first-in-class
epigenetic therapies resulting in various clinical trials around the
world. Among several honors, Dawson was elected to the Australian
Academy of Science and the Australian Academy of Health and Medical
Philip Greenberg, M.D.
Philip Greenberg, M.D., is professor and head of the Program in Immunology at Fred Hutchinson Cancer Center in Seattle, Washington, and he holds the Rona Jaffe Foundation Endowed Chair. Greenberg is an internationally recognized expert in cancer immunotherapy and president-elect of the American Association for Cancer Research. His early discoveries showed how to target diseases using T cells and developed the technology for generating antigen-specific T cells ex vivo for cell therapy, which helped drive the field forward. Greenberg continues to lead efforts to develop and test new strategies to genetically reprogram T cells and to use synthetic biology to even more effectively target many cancer types.
Marcia Haigis, Ph.D.
Marcia Haigis, Ph.D., is professor of Cell Biology and director of
Gender Equity for Faculty in Science at Harvard Medical School. She is
an active member of the Dana Farber/Harvard Cancer Center, the Paul F.
Glenn Center for Biology of Aging Research and the Ludwig Center at
Harvard Medical School. Haigis’ research has made fundamental
contributions to the understanding of how mitochondria mediate
metabolic reprogramming in cancer and contribute to tumor and immune
interactions in the tumor microenvironment. She is a recipient of
numerous awards and was chosen as a National Academy of Medicine
Emerging Leader in Health and Medicine.
Diane Mathis, Ph.D.
Diane Mathis, Ph.D., is professor of Immunology at Harvard Medical School and holds the Morton Grove-Rasmussen Chair of Immunohematology. She is an active member of the Committee on Immunology at Harvard Medical School, the Broad Institute, the Dana-Farber/Harvard Cancer Center and the Harvard Stem Cell Institute. Mathis’ research on T cell differentiation and tolerance/autoimmunity seeks to understand these processes at a mechanistic level and discover how they influence a variety of human diseases. She is a member of the National Academy of Sciences and the American Academy of Arts and Sciences.
Miriam Merad, M.D., Ph.D.
Miriam Merad, M.D., Ph.D., is the director of the Precision
Immunology Institute at the Icahn School of Medicine at Mount Sinai
and the director of the Human Immune Monitoring Center at Mount Sinai
in New York City. She is an internally acclaimed physician-scientist
and leader in the fields of dendritic cell and macrophage biology,
focusing on their contributions to human disease. Merad has identified
new subsets of both macrophages and dendritic cells, both with key
roles in regulating the anti-tumor immune response. She is now working
to develop therapies targeting these unique cell populations in cancer
and other conditions. For her contributions to the field, Merad was
elected to the National Academy of Sciences in 2020.
Kunle Odunsi, M.D., Ph.D.
Kunle Odunsi, M.D., Ph.D., is director of the University of Chicago Medicine Comprehensive Cancer Center and dean for Oncology, Biological Services Division at the University of Chicago. Odunsi is responsible for strategic oversight of all programmatic aspects of cancer at the University of Chicago, including the three primary missions of research, patient care and education. His research in tumor immunology and immunotherapy focuses on the mechanisms of immune recognition in ovarian cancer and on the development of therapies targeting tumor antigens. Odunsi is a member of the National Academy of Medicine.
Phillip Sharp, Ph.D.
Phillip Sharp, Ph.D., is an institute professor at the Massachusetts Institute of Technology and member of the Department of Biology at the Koch Institute for Integrative Cancer Research at MIT. His research interests have centered on the molecular biology of gene expression relevant to cancer and the mechanisms of RNA splicing. His landmark discoveries provided the first indications of “discontinuous genes” in mammalian cells, changing the understanding of gene structure and earning Sharp the 1993 Nobel Prize in Physiology or Medicine. Sharp also is a member of the National Academy of Sciences, the National Academy of Medicine and the American Academy of Arts and Sciences, in addition to many other honors.
Karen Vousden, Ph.D.
Karen Vousden, Ph.D., is a group leader at the Francis Crick
Institute in London, England and former chief scientist for Cancer
Research UK. Her research has made contributions to the understanding
of how the tumor suppressor p53 is regulated and how it functions to
control cancer progression. Vousden revealed an unexpected ability of
p53 to help cells adapt and survive under transient periods of serine
starvation, leading her to focus on cancer cell metabolism and on the
role of oxidative stress and one carbon metabolism in cancer
development and metastatic progression. Among numerous honors, Vousden
is an international member of the National Academy of Sciences and the
American Academy of Arts and Sciences.
Catherine J. Wu, M.D.
Catherine J. Wu, M.D., is the leader of the Division of Stem Cell
Transplantation and Cellular Therapies at Dana-Farber Cancer Institute
in Boston, Massachusetts. She has initiated an integrated program of
research and clinical activities that focuses on dissecting the basis
of effective anti-tumor immunity. Her laboratory has focused on the
use of genomics-based approaches to discover immunogenic antigen
targets and to understand the molecular basis of therapeutic response
and resistance. Wu is a member of the National Academy of Medicine and
has received numerous other awards.