- Emotional & Physical Effects
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- Appetite Changes
- Bleeding and Bruising
- Blood Clots and Anticoagulants
- Body Image
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- Chemobrain
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- Fatigue
- Hair Loss
- Heart Health
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- Lymphedema
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- Neutropenia
- Pulmonary Embolism and Cancer
- Mouth Sores from Chemotherapy
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- Sleep Loss
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Fatigue and Cancer
Fatigue is the most common symptom experienced by cancer patients. It is treatable, but most patients do not report symptoms to their doctor. Cancer-related fatigue can have a serious impact on quality of life, as well as physical symptoms.
The stress of dealing with your cancer diagnosis can cause fatigue. Other causes include:
- Aggressive surgery, chemotherapy or radiation treatments
- Chemotherapy-induced anemia
- Sleep disorders
- Emotional distress
- Pre-existing medical conditions such as uncontrolled diabetes, thyroid problems, heart disease or rheumatoid arthritis
Coping With Fatigue
Try these simple tips to boost your energy and fight fatigue.
- Exercise regularly. A 20-minute walk can help you relax, but don’t exercise in the evening.
- Limit naps if possible. If you must nap, keep it under 30 minutes, and do something active right after waking.
- Avoid alcohol, caffeine, chocolate and nicotine in the evening.
- Turn off the TV one hour before bedtime. Listen to quiet music or take a warm bath instead.
- Keep a regular sleep schedule, even on weekends.
- Do not read, watch TV or work in the bedroom.
- If you haven’t fallen asleep in 15 minutes, go to another room. Avoid mental stimulation and return to bed when you feel sleepy. If you still can’t fall asleep, get up again and repeat these steps.
- Keep a fatigue journal to help find patterns in your fatigue and prioritize your activities.
Patient Education
Print and use these handy documents to help you cope with fatigue.
Fatigue Clinic
Our Internal Medicine Center treats patients with cancer-related fatigue. Ask your MD Anderson health team for a referral to the Fatigue Clinic.
If you’re always feeling physically, mentally or emotionally exhausted, you’re not alone. Fatigue is the most common side effect experienced by patients during and after cancer treatment.
And, because there’s no way to test for cancer-related fatigue, it tends to be underdiagnosed.
The good news is that it’s possible to alleviate cancer-related fatigue. By recognizing the signs and symptoms of fatigue, you can empower yourself to discuss this side effect with your care team and get help.
Here’s what you should know about cancer fatigue, according to our clinical nurse Kim Kitchen.
Cancer-related fatigue is different from the fatigue experienced by healthy people
When healthy people are fatigued from their daily activities, extra rest typically helps. But that’s not always the case for cancer patients. That’s because fatigue can be caused by many cancer treatments, as well as the cancer itself and even other side effects. And that means cancer-related fatigue can last for long periods – and that cancer patients may get tired more easily and by exerting less energy than fatigued healthy individuals.
Cancer and cancer treatment put you at risk for fatigue
Part of the reason fatigue is so common among cancer patients is because it can be caused by so many different aspects of the cancer experience. This includes:
- Cancer treatment, including chemotherapy, hormone therapy, radiation therapy, surgery and even recovery from surgery.
- Anemia, a common side effect of chemotherapy
- Loss of appetite, which may be caused by nausea and vomiting and can keep you from getting enough nutrients, such as vitamin B12, folic acid, iron and protein
- Medications, such as those prescribed for depression, pain, sleep and nausea
- Insomnia, another common cancer treatment side effect
- Anxiety, depression and other mood disturbances, which are often triggered by a cancer diagnosis or treatment
- A decline in physical activity
It’s possible to manage cancer fatigue
Cancer-related fatigue can affect your quality of life and make it harder for your body to heal from cancer treatment. So it’s important to try to manage your cancer-related fatigue. Here’s what Kitchen recommends.
- Get rest, but not too much. Opt for small rest breaks or naps between activities instead of one big nap. That’s because too much rest may make you even drowsier or make it difficult to sleep at night.
- Accept help from others. When people offer to help, take them on it. Let them do things like go to the grocery for you, mow your lawn or drive your kids to school and activities. This way, you can conserve your energy for when you need it.
- Maintain a healthy diet. This can be hard during cancer treatment, especially if you’re dealing with appetite loss or nausea, but do your best to eat enough protein and calories so that your body can get healthy. If you are having trouble getting enough calories and are an MD Anderson patient, ask a member of your care team to refer you to a dietitian.
- Distract yourself. Dance, watch TV, listen to music or read a good book to distract yourself from the fatigue. Doing something you enjoy may also boost your mood.
- Exercise. Though you’re tired, exercise is the best way to reduce cancer-related fatigue. Kitchens recommends taking a brisk walk, or trying cycling, swimming, aerobics, strength training or resistance training – basically, whatever it takes to get you moving, even if it’s only for a few minutes. Bonus: exercise will also help you sleep better and boost your mood.
- Keep a fatigue journal so you can start to see patterns and prioritize your activities.
MD Anderson has resources to help you manage your cancer fatigue
You don’t have to try to manage cancer fatigue alone. Talk to your doctor about the fatigue symptoms you’re experiencing. And, if you’re an MD Anderson patient, ask your doctor to refer you to our Cancer-Related Fatigue Clinic. Our team of doctors and nurses will work with you to develop a comprehensive, personalized plan for managing your fatigue so you can get back to living your life faster.
Request an appointment at MD Anderson online or by calling 1-877-632-6789.

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