- Services
- ABL1 Kinase Domain Mutation Analysis
- Chimerism Assessment by Polymorphic Microsatellite Markers
- Detection of BCR ABL Major Fusion Transcripts
- Detection of BCR ABL Minor Fusion Transcripts
- EndLeukemia RNA Translocation Assay Analysis
- FIP1L1-PDGFRA Fusion Transcript Detection
- FLT3 Mutational Analysis
- hMLH1 Methylation Status
- Immunoglobulin Heavy Chain Gene Rearrangement
- Inv(16)(p13.1q22);CBFB-MYH11 Fusion Transcript Detection
- JAK2 p.V617F Mutational Analysis
- EndLeukemia Assay
- MD EndLymphoma Mutation Analysis
- MD FLT3-ITD Follow up Mutation MRD Analysis
- MD Focused Pharamacogenomics Genotyping Assay
- MD HPV Liquid Biopsy
- MD NPM1 MRD Mutation Analysis
- MDA Mutation Analysis Precision Panel Liquid Biopsy
- MGMT Methylation Status
- Microsatellite Instability Analysis (Tumors)
- PML-RARA/t(15;17) Fusion Transcript Detection
- RUNX1-RUNX1T1/t(8;21)(q22;q22) Fusion Transcript Detection
- Somatic Hypermutation Analysis, IGH
- T cell Receptor Beta Gene Rearrangement
- T cell Receptor Gamma Gene Rearrangement
- TGFB1 Polymorphism Real-Time PCR Genotyping
FIP1L1-PDGFRA Fusion Transcript Detection, RNA-PCR
Indication
This test is for determining the presence or absence of the FIP1L1-PDGFRA fusion transcript produced by an interstitial deletion at chromosome 4q12 that is seen in some cases of hypereosinophilic syndrome and systemic mast cell disease.
This test can be used for diagnosis or for minimal residual disease detection following therapy.
Methodology
RNA is analyzed for FIP1L1-PDGFRA fusions by reverse transcription nested PCR.
Test Parameters
A control RNA sequence is amplified in parallel as a control for sample quality.
Turnaround Time
Five to 10 working days
Sample Requirements
10 ml peripheral blood in purple top tube (EDTA Vacutainer), sent by overnight express mail on wet ice
or
2–5 ml of bone marrow aspirate in purple top tube (EDTA Vacutainer), sent by overnight express mail, sent on wet ice
or
10 µg of purified RNA or cDNA, sent by overnight express mail on dry ice
CPT Codes
81401
The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
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Research Areas
Find out about the four types of research taking place at UT MD Anderson.