Services and Pricing
The Metabolomics Facility guides investigators through the experimental design and statistical considerations of their metabolomics studies. Please contact Phil Lorenzi to schedule an appointment to discuss your project.
Our Services
Targeted Metabolomics:
Anionic Metabolites by IC-MS (80)
- Quantitative analysis of metabolites associated primarily with glycolysis, TCA cycle, and pentose phosphate pathway (download list)
- Pricing:
- Internal & Academic (In Network)-$200/sample
- Academic (Out of Network)-$300/sample (+60% Overhead)
- Non-academic-$400 (+60% Overhead)
Amino Acids (30)
- Quantitative analysis of 18 proteogenic AAs + related metabolites (See list below)
- Pricing:
- Internal & Academic (In Network)-$200/sample
- Academic (Out of Network)-$300/sample (+60% Overhead)
- Non-academic-$400 (+60% Overhead)
Organic Acids (8)
- Quantitative analysis of 8 organic acids (See list below)
- Pricing:
- Internal & Academic (In Network)-$200/sample
- Academic (Out of Network)-$300/sample (+60% Overhead)
- Non-academic-$400/sample (+60% Overhead)
Glutathione (2)
- Quantitative analysis for measurement of reduced (GSH) and oxidized (GSSG) glutathione (See list below)
- Pricing:
- Internal & Academic (In Network)-$200/sample
- Academic (Out of Network)-$300/sample (+60% Overhead)
- Non-academic-$400/sample (+60% Overhead)
Polyamines (14)
- Quantitative analysis for measurement of 14 polyamines
- Pricing:
- Internal & Academic (In Network)-$200/sample
- Academic (Out of Network)-$300/sample (+60% Overhead)
- Non-academic-$400/sample (+60% Overhead)
DNA Damage Metabolites (6)
- Quantitative analysis for measurement of 6 DNA damage metabolites
- Pricing:
- Internal & Academic (In Network)-$200/sample
- Academic (Out of Network)-$300/sample (+60% Overhead)
- Non-academic-$400/sample (+60% Overhead)
Tracer Analysis
- Pricing:
- Internal & Academic (In Network)- $200/sample
- Academic (Out of Network) - $300/sample (+60% Overhead)
- Non-academic- $400/sample (+60% Overhead)
Fatty Acids (Free or Total, separate assays)
- Pricing:
- Internal & Academic (In Network)- $250/sample
- Academic (Out of Network)- $400/sample (+60% Overhead)
- Non-academic- $500/sample (+60% Overhead)
Targeted analysis (Custom)
- Pricing:
- Internal & Academic (In Network)- $200/sample
- Academic (Out of Network)- $300/sample (+60% Overhead)
- Non-academic- $400/sample (+60% Overhead)
Non-targeted Metabolomics:
Profiling (complete)
- Quantitative analysis of metabolites in non-targeted fashion from multiple fractions
- Multiple configurations available
- Pricing:
- Internal & Academic (In Network)-$600/sample
- Academic (Out of Network)-$960 (+60% Overhead)
- Non-academic-$1200/sample (+60% Overhead)
Lipidomic Profiling
- Relative quantitation of multiple classes of lipid metabolites from nonpolar fractions
- Pricing:
- Internal & Academic (In Network)-$300/sample
- Academic (Out of Network)-$480 (+60% Overhead)
- Non-academic-$600/sample (+60% Overhead)
Hyaluronic Acid Profiling
- Relative quantitation of hyaluronic acid (hyaluronan) oligoomers
- Pricing:
- Internal & Academic (In Network)-$450/sample
- Academic (Out of Network)-$720 (+60% Overhead)
- Non-academic-$900/sample (+60% Overhead)
Tracer Analysis (Non-Targeted)
- Quantitative (ratiometric) LC-MS assay for measurement of stable isotope label incorporation into non-targeted metabolites
- Pricing:
- Internal & Academic (In Network)-$600/sample
- Academic (Out of Network)-$960/sample (+60% Overhead)
- Non-academic-$1200/sample (+60% Overhead)
General:
New Assay Setup
- Add new metabolite to existing assay
- Develop new quantitative assay
- Pricing (per day of development time):
- Internal & Academic (In Network)-$600/day
- Academic (Out of Network)-$900/day(+60% Overhead)
- Non-academic-$1,200/day(+60% Overhead)
Sample Preparation Assistance
- Assistance with or full-service provision of sample preparation
- Pricing:
- Internal & Academic (In Network)-$200/sample
- Academic (Out of Network)-$300/sample (+60% Overhead)
- Non-academic-$400/sample (+60% Overhead)
Equipment Usage
- For trained users only
- Pricing:
- Internal & Academic (In Network)-$100/hr
- Academic (Out of Network)-$200/hr (+60% Overhead)
- Non-academic-$200/hr (+60% Overhead)
Data Analysis
- MS generated by core facility
- Pricing:
- Internal & Academic (In Network)- $100/h
- Academic (Out of network)- $200/h(+60% Overhead)
- Non-academic- $200/h (+60% Overhead)
- Data not generated by core facility (e.g. genomics, RPPA, microarry, sequencing, drug combination effects, etc.)
- Pricing:
- Internal & Academic (In Network)- $200/h
- Academic (Out of network)- $400/h (+60% Overhead)
- Non-academic- $400/h (+60% Overhead)
Additional Services
We provide redox metabolism assays for relative quantitation of ROS (H2O2) using microplate (96-well) assay, and we are experienced in mechanism of action studies that involve integrating pharmacological endpoints (e.g., cell viability) with metabolomic and other omic data. Please contact Phil Lorenzi to discuss.
FAQs
Find answers to frequently asked questions, including which type of assay you may need and how to get started.
Targeted Metabolites List
Amino Acids
1. 4-hydroxy-proline
2. acetylcholine
3. alanine (Ala)
4. arginine (Arg)
5. asparagine (Asn)
6. carnitine
7. citrulline
8. creatine
9. creatinine
10. cysteine (Cys)
11. cystine (Cys-Cys disulfide)
12. gamma-aminobutyric acid (GABA)
13. glutamine (Gln)
14. glycine (Gly)
15. histidine (His)
| 4-hydroxy-proline | 16. | isoleucine (Ile) | |
| 2. | acetylcholine | 17. | leucine (Leu) |
| 3. | alanine (Ala) | 18. | lysine (Lys) |
| 4. | arginine (Arg) | 19. | methionine (Met) |
| 5. | asparagine (Asn) | 20. | S-adenosylhomocysteine (SAH) |
| 6. | carnitine | 21. | ornithine |
| 7. | citrulline | 22. | phenylalanine (Phe) |
| 8. | creatine | 23. | proline (Pro) |
| 9. | creatinine | 24. | sarcosine |
| 10. | cysteine (Cys) | 25. | serine (Ser) |
| 11. | cystine (Cys-Cys disulfide) | 26. | taurine |
| 12. | gamma-aminobutyric acid (GABA) | 27. | threonine (Thr) |
| 13. | glutamine (Gln) | 28. | tryptophan (Trp) |
| 14. | glycine (Gly) | 29. | tyrosine (Tyr) |
| 15. | histidine (His) | 30. | valine (Val) |
16. isoleucine (Ile)
17. leucine (Leu)
18. lysine (Lys)
19. methionine (Met)
20. S-adenosylhomocysteine (SAH)
21. ornithine
22. phenylalanine (Phe)
23. proline (Pro)
24. sarcosine
25. serine (Ser)
26. taurine
27. threonine (Thr)
28. tryptophan (Trp)
29. tyrosine (Tyr)
30. valine (Val)
| 4-hydroxy-proline | 16. | isoleucine (Ile) | |
| 2. | acetylcholine | 17. | leucine (Leu) |
| 3. | alanine (Ala) | 18. | lysine (Lys) |
| 4. | arginine (Arg) | 19. | methionine (Met) |
| 5. | asparagine (Asn) | 20. | S-adenosylhomocysteine (SAH) |
| 6. | carnitine | 21. | ornithine |
| 7. | citrulline | 22. | phenylalanine (Phe) |
| 8. | creatine | 23. | proline (Pro) |
| 9. | creatinine | 24. | sarcosine |
| 10. | cysteine (Cys) | 25. | serine (Ser) |
| 11. | cystine (Cys-Cys disulfide) | 26. | taurine |
| 12. | gamma-aminobutyric acid (GABA) | 27. | threonine (Thr) |
| 13. | glutamine (Gln) | 28. | tryptophan (Trp) |
| 14. | glycine (Gly) | 29. | tyrosine (Tyr) |
| 15. | histidine (His) | 30. | valine (Val) |
Organic Acids
1. glutamate (Glu)
2. glutamine (Gln)
3. aspartate (Asp)
4. alpha-ketoglutarate (a-KG)
5. 2-hydroxyglutarate (2-HG)
6. pyruvate
7. lactate
8. pyroglutamic acid (pGlu)
Glutathione
1. glutathione, reduced (GSH)
2. glutathione, oxidized (GSSG)
Polyamines
1. tyramine
2. putrescine
3. tryptamine
4. agmatine
5. N-acetylputrescine
6. hypusine
7. diacetylspermine
8. diaminopropane
9. ornithine
10. N-acetylspermine
11. diaminohexane
12. spermidine
13. cadaverine
14. spermine
DNA Damage Metabolites
1. NAD(+)
2. AMP
3. NADH
4. ADP-ribose
5. ADP
6. ATP
Sample Submission
To set an appointment and discuss the details of your experimental design, please email Phil Lorenzi.
**Note: Samples will not be accepted without an appointment.
- Visit https://mdanderson.ilabsolutions.com to register for an account. Once your account is set up, you can requests services through the Metabolomics iLab webpage.
- Upon approval of your online service request, you will be notified via email to set an appointment for sample drop off.
For any technical issues with registering your iLab account, please contact iLab Solutions Support.
External Overhead Fees
All external institutions are subject to a 60% overhead fee unless listed below:
- UT Systems
- Baylor College of Medicine
- Rice University
- University of Houston
- Texas A&M Institute of Biosciences & Technology (IBT)
- Houston Methodist Research Institute (HMRI)