Bioinformatics faculty members in the Department of Epigenetics and Molecular Carcinogenesis work collaboratively with investigators to provide novel computational methods, tools and algorithms for the advancement of cancer disease research. Our bioinformatics faculty engage in collaborative research in the areas of bioinformatics, statistical genetics and systems biology to retrieve and analyze various kinds of biological data including DNA/RNA sequences, protein sequences and structures, microarray data and RT-PCR data for the purpose of facilitating biological discovery. Special emphasis is placed on next-generation sequencing data analysis.
Biostatistics services are provided with additional support from faculty in the Division of Quantitative Sciences in Houston. Many modern research projects generate data sets that require statistical analysis. Biostatistics staff provide expertise throughout such projects from early project conception to fully elaborated study design as well as during data collection and data analysis. Early statistical planning helps design more cost-effective projects based on statistical power calculations to help determine the appropriate size and scope of a study as well as how to design a study for more meaningful data collection and analysis.
Research Areas and Projects
- Developing working relationships with MD Anderson research faculty and external collaborators to expand the use of advanced computational techniques and statistical analyses, especially as related to the CPRIT funded Next-Generation Sequencing Core and the separate DNA Methylation Analysis Core (RNA-Seq, DNA-Seq, ChIP-Seq and DNA methylation sequencing)
- Providing guidance to faculty, students and coworkers in the use of specialized applications, programming, computation, and statistical analysis techniques for interpretation of biological data
- Conducting computational biology and bioinformatics/biostatistics seminars and workshops for researchers and students
- Co-developing or contributing to grant proposals with research faculty, professional colleagues and external collaborators to apply advanced computing and related bioinformatics research to the study of human cancers and disease
- Maintaining awareness of emerging computational technologies and new statsticial methods, especially to work with large data sets
Bioinformatics Faculty and Staff
The Virginia Harris Cockrell Cancer Research Center at the University of Texas MD Anderson Cancer Center, Science Park, Department of Epigenetics and Molecular Carcinogenesis
Mailing Address: P.O. Box 389, Smithville, Texas 78957
Physical Address: 1808 Park Road 1C, Smithville, Texas 78957
Yue Lu, Ph.D.
Epigenetics and Molecular Carcinogenesis