About
The CPRIT Advanced Spatial Genomics (ASG) core was established to provide spatial transcriptomics and genomics to cancer researchers at MD Anderson, the Texas Medical Center and the greater state of Texas.
Spatial Genomics (SG) is an exciting new field of genomics that coalesces the fields of imaging, histopathology, and data science with genomic assays to link genomic data with morphological and cellular features to study cancer tissues. SG methods can delineate the tumor microenvironment (TME) and resolve the clonal substructure of cancer cells within a spatial context in tissue sections. These methods are particularly impactful for studying areas of cancer research including premalignant disease progression, invasion, metastatic disease, therapeutic resistance and immune-oncology.
Over the last few years, the SG field has rapidly expanded with the development of several new commercial technologies. However, most SG technologies have remained in the hands of expert laboratories, due to the need for specialized equipment, tissue processing and imaging expertise, and complex data analysis and storage requirements.
To provide this important resource, we have established the CPRIT ASG core facility. The core is directed by Dr. Nicholas Navin and managed by Tuan Tran. This facility provides comprehensive services and expertise for tissue processing, slide imaging, spatial genomics technologies and spatial data analysis methods.
Services
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Instruments
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Team
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