Research

The Zhang Lab utilizes next generation sequencing technology and computational biology approach to analyze the molecular inter- and intra-tumor heterogeneity of lung cancer and the complex interaction between cancer cells of particular molecular features and the host immune system. Key lab interests include investigating the molecular mechanisms of genomic intra-tumor heterogeneity; investigating the potential of genomic heterogeneity analyses in diagnosis and prognosis of lung cancers; investigating the molecular timing and mode of lung cancer metastasis; investigating molecular mechanism underlying histology determination of lung cancers; investigating the role of host immune surveillance in radiation-induced “bystander effect” ect.