We are developing novel clinical applications of combined photoacoustic-ultrasonic imaging.
Today’s health care climate calls for medical technology that provides a safe, inexpensive, patient-specific and point-of care diagnostic and therapeutic solution.
Ultrasound-mediated imaging technologies, such as photoacoustic (PA) or elasticity imaging, allow clinicians to probe a patient’s specific molecular composition, permit assessment of tissue viscoelasticity or afford unprecedented contrast for real-time image-guided therapy. Ultrasound-mediated imaging solutions can be provided at a price point, convenienceand operating ease that permits bedside utilization or straightforward intraoperative integration.
Consequently, I have focused my research program on clinical photoacoustic-ultrasonic (PAUS) and acoustic radiation force (ARF)-based elasticity imaging technologies. Specifically, I am investigating novel uses of PAUS and ARF-based imaging in the detection, assessment and treatment of cancer and cardiac disease.
Although my primary research focus is the development of clinical techniques, I have also invested considerable effort in preclinical (i.e., murine model) PAUS imaging of molecular (i.e., nano-scale) theranostic probes, some of which share translational relevance with the aforementioned clinical applications.