Nicholas Navin, Ph.D.
Areas of Research
- Genomics Research
- Breast Cancer Research
- Genetics Research
Welcome to the Navin Laboratory at MD Anderson Cancer Center. We are a cancer genomics and computational biology research lab. Our laboratory has pioneered the development of single cell sequencing technologies. We apply these tools to study complex biological processes that occur in human cancers including transformation, clonal evolution, invasion, metastasis and chemoresistance evolution. These processes have previously been difficult to study with genomic technologies using bulk tissues.
The efforts of our laboratory are split evenly between experimental and computational biology. We develop new experimental methods to sequence single cells and isolate rare subpopulations and develop new analytical approaches to detect variants and apply statistical methods to these data sets.
His single-cell solution is revolutionizing cancer research
Nicholas Navin wanted to better understand how tumors grow and evolve, so he found a way to analyze the DNA of individual cells
Single-Cell Sequencing Pioneer Wins AAAS Wachtel Cancer Research Award
The first method for sequencing the genome of an individual cell - which has give scientists a new view into the inner workings of tumors - started as a side project during Nicholas Navin's graduate career.
Navin Lab in Action
‘Bursts’ of chromosome changes fuel breast cancer tumor growth
Our new study used single cell sequencing technology to provide previously unknown details about how and when CNAs impact tumor formation and growth, information that may have significant implications for diagnosis and treatment.
Awards & Accolades
Jack and Beveraly Randall Prize for Excellence in Cancer Treatment
ACS Research Scholar
Sabin Family Fellowship
President's Achievement Award
AAAS Wachtel Prize for Young Scientists
Faculty Educator Award
Wilson Stone Award
T.C. Hsu Award for Young Investigators
Damon Runyon-Rachleff Innovation
Young Investigator Award