Publications

2019

Kisling K, Zhang L, Simonds H, Fakie N, Yang J, McCarroll R, Balter P, Burger H, Bogler O, Howell R, Schmeler K, Mejia M, Beadle BM, Jhingran A, Court L. Fully Automatic Treatment Planning for External-Beam Radiation Therapy of Locally Advanced Cervical Cancer: A Tool for Low-resource Clinics. J Global Oncol 2019(1-9), 1/2019.

2018

Tang C, Hobbs B, Amer A, Li X, Behrens C, Canales JR, Cuentas EP, Villalobos P, Fried D, Chang JY, Hong DS, Welsh JW, Sepesi B, Court L, Wistuba II, Koay EJ. Development of an Immune-Pathology Informed Radiomics Model for Non-Small Cell Lung Cancer. Sci Rep 8(1):1922, 1/2018. e-Pub 1/2018. PMCID: PMC5792427.

Ger RB, Cardenas CE, Anderson BM, Yang J, Mackin DS, Zhang L, Court LE. Guidelines and Experience Using Imaging Biomarker Explorer (IBEX) for Radiomics. J Vis Exp(131), 1/2018. e-Pub 1/2018. PMID: 29364284.

Steinmann A, Stafford RJ, Sawakuchi G, Wen Z, Court L, Fuller CD, Followill D. Developing and characterizing MR/CT-visible materials used in QA phantoms for MRgRT systems. Med Phys 45(2):773-782, 2/2018. e-Pub 12/2017. PMCID: PMC5807190.

Mackin D, Ger R, Dodge C, Fave X, Chi PC, Zhang L, Yang J, Bache S, Dodge C, Jones AK, Court L. Effect of tube current on computed tomography radiomic features. Sci Rep 8(1):2354, 2/2018. e-Pub 2/2018. PMCID: PMC5799381.

Jensen GL, Yost CM, Mackin DS, Fried DV, Zhou S, Court LE, Gomez DR. Prognostic value of combining a quantitative image feature from positron emission tomography with clinical factors in oligometastatic non-small cell lung cancer. Radiother Oncol 126(2):362-367, 2/2018. e-Pub 11/2017. PMID: 29196095.

Wang J, Zhang Y, Zhang L, Dong L, Balter PA, Court LE, Yang J. Technical Note: Solving the "Chinese postman problem" for effective contour deformation. Med Phys 45(2):767-772, 2/2018. e-Pub 12/2017. PMID: 29178498.

Elhalawani H, Ger RB, Mohamed ASR, Awan MJ, Ding Y, Li K, Fave XJ, Beers AL, Driscoll B, Hormuth II DA, van Houdt PJ, He R, Zhou S, Mathieu KB, Li H, Coolens C, Chung C, Bankson JA, Huang W, Wang J, Sandulache VC, Lai SY, Howell RM, Stafford J, Yankeelov TE, van der Heide UA, Frank SJ, Barboriak DP, Hazle JD, Court LE, Kalpathy-Cramer J, Fuller D. Erratum: Dynamic contrast-enhanced magnetic resonance imaging for head and neck cancers. Scientific Data 5:180041, 3/2018.

Yan Y, Yang J, Beddar S, Ibbott G, Wen Z, Court LE, Hwang KP, Kadbi M, Krishnan S, Fuller CD, Frank SJ, Yang J, Balter P, Kudchadker RJ, Wang J. A methodology to investigate the impact of image distortions on the radiation dose when using
magnetic resonance images for planning. Phys Med Biol 63(8):085005, 4/2018. e-Pub 4/2018. PMID: 29528037.

Court LE, Kisling K, McCarroll R, Zhang L, Yang J, Simonds H, du Toit M, Trauernicht C, Burger H, Parkes J, Mejia M, Bojador M, Balter P, Branco D, Steinmann A, Baltz G, Gay S, Anderson B, Cardenas C, Jhingran A, Shaitelman S, Bogler O,
Schmeller K, Followill D, Howell R, Nelson C, Peterson C, Beadle B. Radiation Planning Assistant - A Streamlined, Fully Automated Radiotherapy Treatment Planning System. J Vis Exp(134), 4/2018. e-Pub 4/2018. PMCID: PMC5933447.

Jiang M, Yang P, Mackin D, Elhalawani H, Zhang Z, Peng W, Shi Y, Wang H, Jin H, Mohamed A, Court L, Fuller CD, Wu L. An imaging/biology correlation study between radiomics features and anaplastic lymphoma kinase (ALK) mutational status in a uniform Chinese cohort of locally advance lung adenocarcinomas. J Clin Oncol 36(15):e20540-e20540, 5/2018.

Court L, Wang H, Aten D, Brown D, MacGregor H, du Toit M, Chi M, Gao S, Yock A, Aristophanous M, Balter P. Illustrated instructions for mechanical quality assurance of a medical linear accelerator. J Appl Clin Med Phys 19(3):355-359, 5/2018. e-Pub 3/2018. PMCID: PMC5978554.

Li Y, Netherton T, Nitsch PL, Balter PA, Gao S, Klopp AH, Court LE. Normal tissue doses from MV image-guided radiation therapy (IGRT) using orthogonal MV and MV-CBCT. J Appl Clin Med Phys 19(3):52-57, 5/2018. e-Pub 3/2018. PMCID: PMC5978715.

Zhang Z, Yang J, Ho A, Jiang W, Logan J, Wang X, Brown PD, McGovern SL, Guha-Thakurta N, Ferguson SD, Fave X, Zhang L, Mackin D, Court LE, Li J. A predictive model for distinguishing radiation necrosis from tumour progression after gamma knife radiosurgery based on radiomic features from MR images. Eur Radiol 28(6):2255-2263, 6/2018. e-Pub 11/2017. PMCID: PMC6036915.

Kisling K, Ger R, Cardenas C, Rubinstein A, Netherton T, Ingram W, Fave X, Owens C, Anderson  B, Lee J, Gay S, Yang J, McCarroll R, Mackin D, Li Y, Rhee D, Edward S, He Y, David S, Nitsch P, Balter P, Court L. Broadening the Graduate School Experience: Paper-In-A-Day. Med Phys 45(6):E195-E196, 6/2018.

Cardenas CE, McCarroll RE, Court LE, Elgohari BA, Elhalawani H, Fuller CD, Kamal MJ, Meheissen MAM, Mohamed ASR, Rao A, Williams B, Wong A, Yang J, Aristophanous M. Deep Learning Algorithm for Auto-Delineation of High-Risk Oropharyngeal Clinical Target Volumes With Built-In Dice Similarity Coefficient Parameter Optimization Function. Int J Radiat Oncol Biol Phys 101(2):468-478, 6/2018. e-Pub 2/2018. PMID: 29559291.

Jiang XE, Xu T, Wei Q, Li P, Gomez DR, Court LE, Liao Z. DNA repair capacity correlates with standardized uptake values from 18F-fluorodeoxyglucose positron emission tomography/CT in patients with advanced non-small-cell lung cancer. Chronic Dis Transl Med 4(2):109-116, 6/2018. e-Pub 6/2018. PMCID: PMC6034006.

Ger R, Mackin D, Zhou S, Chi P, Lee H, Layman R, Jones A, Goff D, Fuller C, Howell R, Li H, Stafford R, Court L. Harmonized CT Protocols for High Quality Radiomics Studies. Med Phys 45(6):E677-E678, 6/2018.

Netherton T, Li Y, Nitsch P, Shaitelman S, Balter P, Gao S, Klopp A, Muruganandham M, Court L. Interplay effect on a 6-MV flattening-filter-free linear accelerator with high dose rate and fast multi-leaf collimator motion treating breast and lung phantoms. Med Phys 45(6):2369-2376, 6/2018. e-Pub 4/2018. PMID: 29611210.

McCarroll RE, Beadle BM, Balter PA, Burger H, Cardenas CE, Dalvie S, Followill DS, Kisling KD, Mejia M, Naidoo K, Nelson CL, Peterson CB, Vorster K, Wetter J, Zhang L, Court LE, Yang J. Retrospective Validation and Clinical Implementation of Automated Contouring of Organs at Risk in the Head and Neck: A Step Toward Automated Radiation Treatment Planning for Low- and Middle-Income Countries. J Glob Oncol 4(4):1-11, 7/2018. PMCID: PMC6223488.

Ger RB, Yang J, Ding Y, Jacobsen MC, Cardenas CE, Fuller CD, Howell RM, Li H, Stafford RJ, Zhou S, Court LE. Synthetic head and neck and phantom images for determining deformable image registration accuracy in magnetic resonance imaging. Med Phys. e-Pub 7/2018. PMID: 30007075.

Ger RB, Zhou S, Chi PM, Lee HJ, Layman RR, Jones AK, Goff DL, Fuller CD, Howell RM, Li H, Stafford RJ, Court LE, Mackin DS. Comprehensive Investigation on Controlling for CT Imaging Variabilities in Radiomics Studies. Sci Rep 8(1):13047, 8/2018. e-Pub 8/2018. PMCID: PMC6115360.

Zhang Z, Yang J, Ho A, Jiang W, Logan J, Wang X, Brown PD, McGovern SL, Guha-Thakurta N, Ferguson SD, Fave X, Zhang L, Mackin D, Court LE, Li J. Correction to: A predictive model for distinguishing radiation necrosis from tumour progression after gamma knife radiosurgery based on radiomic features from MR images. Eur Radiol 28(8):3570-3571, 8/2018. e-Pub 3/2018. PMID: 29541912.

Li Y, Netherton T, Nitsch PL, Gao S, Klopp AH, Balter PA, Court LE. Independent validation of machine performance check for the Halcyon and TrueBeam linacs for daily quality assurance. J Appl Clin Med Phys 19(5):375-382, 9/2018. e-Pub 7/2018. PMCID: PMC6123154.

Riley C, Cox C, Graham S, Havran H, Kramer B, Netherton T, Peterson C, Williamson T, Court L. Varian Halcyon dosimetric comparison for multiarc VMAT prostate and head-and-neck cancers. Med Dosim. e-Pub 9/2018. PMID: 30197035.

Luo Y, Xu Y, Liao Z, Gomez D, Wang J, Jiang W, Zhou R, Williamson R, Court LE, Yang J. Automatic segmentation of cardiac substructures from noncontrast CT images: accurate enough for dosimetric analysis? Acta Oncol:1-7. e-Pub 10/2018. PMID: 30306817.

Kisling KD, Ger RB, Netherton TJ, Cardenas CE, Owens CA, Anderson BM, Lee J, Rhee DJ, Edward SS, Gay SS, He Y, David SD, Yang J, Nitsch PL, Balter PA, Urbauer DL, Peterson CB, Court LE, Dube S. A snapshot of medical physics practice patterns. J Appl Clin Med Phys 19(6):306-315, 11/2018. e-Pub 10/2018. PMCID: PMC6236839.

Cardenas CE, Anderson BM, Aristophanous M, Yang J, Rhee DJ, McCarroll RE, Mohamed ASR, Kamal M, Elgohari BA, Elhalawani HM, Fuller CD, Rao A, Garden AS, Court LE. Auto-delineation of oropharyngeal clinical target volumes using 3D convolutional neural networks. Phys Med Biol 63(21):215026, 11/2018. e-Pub 11/2018. PMID: 30403188.

Scarboro SB, Cody D, Stingo FC, Alvarez P, Followill D, Court L, Zhang D, McNitt-Gray M, Kry SF. Calibration strategies for use of the nanoDot OSLD in CT applications. J Appl Clin Med Phys. e-Pub 11/2018. PMID: 30426664.

Yu W, Tang C, Hobbs BP, Li X, Koay EJ, Wistuba II, Sepesi B, Behrens C, Rodriguez Canales J, Parra Cuentas ER, Erasmus JJ, Court LE, Chang JY. Development and Validation of a Predictive Radiomics Model for Clinical Outcomes in Stage I Non-small Cell Lung Cancer. Int J Radiat Oncol Biol Phys 102(4):1090-1097, 11/2018. e-Pub 11/2017. PMID: 29246722.

Ger RB, Craft DF, Mackin DS, Zhou S, Layman RR, Jones AK, Elhalawani H, Fuller CD, Howell RM, Li H, Stafford RJ, Court LE. Practical guidelines for handling head and neck computed tomography artifacts for quantitative image analysis. Comput Med Imag Graph 69:134-139, 11/2018. e-Pub 9/2018. PMCID: PMC6217839.

Krafft SP, Rao A, Stingo F, Briere TM, Court LE, Liao Z, Martel MK. The utility of quantitative CT radiomics features for improved prediction of radiation pneumonitis. Med Phys 45(11):5317-5324, 11/2018. e-Pub 9/2018. PMID: 30133809.

Mackin D, Ger R, Gay S, Dodge C, Zhang L, Yang J, Jones AK, Court L. Matching and Homogenizing Convolution Kernels for Quantitative Studies in Computed Tomography. Invest Radiol. e-Pub 12/2018. PMID: 30570504.

Owens CA, Peterson CB, Tang C, Koay EJ, Yu W, Mackin DS, Li J, Salehpour MR, Fuentes DT, Court LE, Yang J. Lung tumor segmentation methods: Impact on the uncertainty of radiomics features for non-small cell lung cancer. PLoS One 13(10):e0205003, 2018. e-Pub 10/2018. PMCID: PMC6171919.

Elhalawani H, Lin TA, Volpe S, Mohamed ASR, White AL, Zafereo J, Wong AJ, Berends JE, AboHashem S, Williams B, Aymard JM, Kanwar A, Perni S, Rock CD, Cooksey L, Campbell S, Yang P, Nguyen K, Ger RB, Cardenas CE, Fave XJ, Sansone C, Piantadosi G, Marrone S, Liu R, Huang C, Yu K, Li T, Yu Y, Zhang Y, Zhu H, Morris JS, Baladandayuthapani V, Shumway JW, Ghosh A, Pöhlmann A, Phoulady HA, Goyal V, Canahuate G, Marai GE, Vock D, Lai SY, Mackin DS, Court LE, Freymann J, Farahani K, Kaplathy-Cramer J, Fuller CD. Machine Learning Applications in Head and Neck Radiation Oncology: Lessons From Open-Source Radiomics Challenges. Front Oncol 8:294, 2018. e-Pub 8/2018. PMCID:
PMC6107800.

Rubinstein AE, Gay S, Peterson CB, Kingsley CV, Tailor RC, Pollard-Larkin JM, Melancon AD, Followill DS, Court LE. Radiation-induced lung toxicity in mice irradiated in a strong magnetic field. PLoS One 13(11):e0205803, 2018. e-Pub 11/2018. PMCID: PMC6239291.

2017

Shafiq-Ul-Hassan M, Zhang GG, Latifi K, Ullah G, Hunt DC, Balagurunathan Y, Abdalah MA, Schabath MB, Goldgof DG, Mackin D, Court LE, Gillies RJ, Moros EG. Intrinsic dependencies of CT radiomic features on voxel size and number of gray levels. Med Phys 44(3):1050-1062, 3/2017. e-Pub 1/2017. PMCID: PMC5462462.

Fave X, Zhang L, Yang J, Mackin D, Balter P, Gomez D, Followill D, Jones AK, Stingo F, Liao Z, Mohan R, Court L. Delta-radiomics features for the prediction of patient outcomes in non-small cell lung cancer. Sci Rep 7(1):588, 4/2017. e-Pub 4/2017. PMCID: PMC5428827.

Yasaka K, Akai H, Mackin D, Court L, Moros E, Ohtomo K, Kiryu S. Precision of quantitative computed tomography texture analysis using image filtering: A phantom study for scanner variability. Medicine (Baltimore) 96(21):e6993, 5/2017. PMCID: PMC5457888.

Fave X, Zhang L, Yang J, Mackin D, Balter P, Gomez DR, Followill D, Jones AK, Stingo F, Mohan R, Liao Z, Court LE. Using Pretreatment Radiomics and Delta-Radiomics Features to Predict Non-Small Cell Lung Cancer Patient Outcomes. Int J Radiat Oncol Biol Phys 98(1):249, 5/2017. PMID: 28587041.

Niedzielski JS, Yang J, Stingo F, Liao Z, Gomez D, Mohan R, Martel M, Briere T, Court L. A Novel Methodology using CT Imaging Biomarkers to Quantify Radiation Sensitivity in the Esophagus with Application to Clinical Trials. Sci Rep 7(1):6034, 7/2017. e-Pub 7/2017. PMCID: PMC5519548.

Rubinstein AE, Ingram WS, Anderson BM, Gay SS, Fave XJ, Ger RB, McCarroll RE, Owens CA, Netherton TJ, Kisling KD, Court LE, Yang J, Li Y, Lee J, Mackin DS, Cardenas CE. Cost-effective immobilization for whole brain radiation therapy. J Appl Clin Med Phys 18(4):116-122, 7/2017. e-Pub 6/2017. PMCID: PMC5874864.

Wang Q, Zhou S, Court LE, Verma V, Koay EJ, Zhang L, Zhang W, Tang C, Lin S, Welsh JD, Blum M, Betancourt S, Maru D, Hofstetter WL, Chang JY. Radiomics predicts clinical outcome in primary gastroesophageal junction adenocarcinoma treated by chemo/radiotherapy and surgery. Phys Imaging Rad Oncol 3:37-42, 7/2017.

Ingram WS, Yang J, Wendt R, Beadle BM, Rao A, Wang XA, Court LE. The influence of non-rigid anatomy and patient positioning on endoscopy-CT image registration in the head and neck. Med Phys 44(8):4159-4168, 8/2017. e-Pub 6/2017. PMID: 28513864.

Ger RB, Mohamed ASR, Awan MJ, Ding Y, Li K, Fave XJ, Beers AL, Driscoll B, Elhalawani H, Hormuth DA, Houdt PJV, He R, Zhou S, Mathieu KB, Li H, Coolens C, Chung C, Bankson JA, Huang W, Wang J, Sandulache VC, Lai SY, Howell RM, Stafford RJ, Yankeelov TE, Heide UAV, Frank SJ, Barboriak DP, Hazle JD, Court LE, Kalpathy-Cramer J, Fuller CD. A Multi-Institutional Comparison of Dynamic Contrast-Enhanced Magnetic Resonance Imaging Parameter Calculations. Sci Rep 7(1):11185, 9/2017. e-Pub 9/2017. PMCID: PMC5593829.

Ger RB, Yang J, Ding Y, Jacobsen MC, Fuller CD, Howell RM, Li H, Jason Stafford R, Zhou S, Court LE. Accuracy of deformable image registration on magnetic resonance images in digital and physical phantoms. Med Phys 44(10):5153-5161, 10/2017. e-Pub 7/2017. PMCID: PMC5962957.

McCarroll R, Youssef B, Beadle B, Bojador M, Cardan R, Famiglietti R, Followill D, Ibbott G, Jhingran A, Trauernicht C, Balter P, Court L. Model for Estimating Power and Downtime Effects on Teletherapy Units in Low-Resource Settings. J Glob Oncol 3(5):563-571, 10/2017. e-Pub 1/2017. PMCID: PMC5646876.

Faught JT, Balter PA, Johnson JL, Kry SF, Court LE, Stingo FC, Followill DS. An FMEA evaluation of intensity modulated radiation therapy dose delivery failures at tolerance criteria levels. Med Phys 44(11):5575-5583, 11/2017. e-Pub 10/2017. PMID: 28862765.

Yang J, Haas B, Fang R, Beadle BM, Garden AS, Liao Z, Zhang L, Balter P, Court L. Atlas ranking and selection for automatic segmentation of the esophagus from CT scans. Phys Med Biol 62(23):9140-9158, 11/2017. e-Pub 11/2017. PMID: 29049027.

Niedzielski JS, Yang J, Mohan R, Titt U, Mirkovic D, Stingo F, Liao Z, Gomez DR, Martel MK, Briere TM, Court LE. Differences in Normal Tissue Response in the Esophagus Between Proton and Photon Radiation Therapy for Non-Small Cell Lung Cancer Using In Vivo Imaging Biomarkers. Int J Radiat Oncol Biol Phys 99(4):1013-1020, 11/2017. e-Pub 7/2017. PMID: 29063837.

Ho JH, Hagler S, Lujano C, Seng S, Starks C, Perrin K, Turner L, Court L. Can cost make a difference dosimetrically? Volumetric modulated arc therapy study for multileaf collimators of various widths for head and neck and prostate cancers. Med Dosim 42(1):12-17, Spring, 2017. e-Pub 1/2017. PMID: 28126474.

Parikh AM, Coletta AM, Yu ZH, Rauch GM, Cheung JP, Court LE, Klopp AH. Development and validation of a rapid and robust method to determine visceral adipose tissue volume using computed tomography images. PLoS One 12(8):e0183515, 2017. e-Pub 8/2017. PMCID: PMC5578607.

Mackin D, Fave X, Zhang L, Yang J, Jones AK, Ng CS, Court L. Harmonizing the pixel size in retrospective computed tomography radiomics studies. PLoS One 12(9):e0178524, 2017. e-Pub 9/2017. PMCID: PMC5608195.

2016

Sn van Rossum P, Xu C, Fried D, Goense L, Court L, Lin S. The emerging field of radiomics in esophageal cancer:  current evidence and future potential. Transl Can Res 5(4):410-423, 2016.

Court LE, Rao A, Krishnan S. Radiomics in cancer diagnosis, cancer staging, and prediction of response to treatment. Transl Can Res 5(4):337-339, 2016.

Fave X, Zhang L, Yang J, Mackin D, Balter P, Gomez D, Followill D, Jones AK, Stingo F, Court LE. Impact of image preprocessing on the volume dependence and prognostic potential of radiomics features in non-small cell lung cancer. Transl Can Res 5(4):349-363, 2016.

Court LE, Fave X, Mackin D, Lee J, Yang J, Zhang L. Computational resources for radiomics. Transl Can Res 5(4):340-348, 2016.

Niedzielski JS, Yang J, Liao Z, Gomez DR, Stingo F, Mohan R, Martel MK, Briere TM, Court LE. (18)F-Fluorodeoxyglucose Positron Emission Tomography Can Quantify and Predict Esophageal Injury During Radiation Therapy. Int J Radiat Oncol Biol Phys 96(3):670-8, 11/2016. e-Pub 7/2016. PMCID: PMC5117825.

Sandulache VC, Hobbs BP, Mohamed ASR, Frank SJ, Song J, Ding Y, Ger R, Court LE, Kalpathy-Cramer J, Hazle JD, Wang JH, Awan MJ, Rosenthal DI, Garden AS, Gunn GB, Colen RR, Rivka R, Elshafeey N, Elbanan M, Hutcheson KA, Lewin JS, Chambers MS, Hofstede TM, Weber RS, Lai SY, Fuller CD.
Dynamic contrast-enhanced MRI detects acute radiotherapy-induced alterations in mandibular microvasculature:  prospective assessment of imaging biomarkers of normal tissue injury. Sci Rep 6(29864), 8/2016.

van Rossum PS, Fried DV, Zhang L, Hofstetter WL, van Vulpen M, Meijer GJ, Court LE, Lin SH. The incremental value of subjective and quantitative assessment of 18F-FDG PET for the prediction of pathologic complete response to preoperative chemoradiotherapy in esophageal cancer. J Nucl Med. e-Pub 1/2016. PMID: 26795288.

Fried DV, Mawlawi O, Zhang L, Fave X, Zhou S, Ibbott G, Liao Z, Court LE. Potential Use of (18)F-fluorodeoxyglucose Positron Emission Tomography-Based Quantitative Imaging Features for Guiding Dose Escalation in Stage III Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys 94(2):368-76, 2/2016. e-Pub 10/2015. PMID: 26853345.

Matney JE, Park PC, Li H, Court LE, Zhu XR, Dong L, Liu W, Mohan R. Perturbation of water-equivalent thickness as a surrogate for respiratory motion in proton therapy. J Appl Clin Med Phys 17(2):5795, 8/2016. PMID: 27074459.

Yu ZH, Kudchadker R, Dong L, Zhang Y, Court LE, Mourtada F, Yock A, Tucker SL, Yang J. Learning anatomy changes from patient populations to create artificial CT images for voxel-level validation of deformable image registration. J Appl Clin Med Phys 17(1):246-258, 2016. e-Pub 1/2016. PMID: 26894362.

2015

Fried DV, Mawlawi O, Zhang L, Fave X, Zhou S, Ibbott G, Liao Z, Court LE. Stage III Non-Small Cell Lung Cancer: Prognostic Value of FDG PET Quantitative Imaging Features Combined with Clinical Prognostic Factors. Radiology:142920. e-Pub 7/2015. PMID: 26176655.

Ebe K, Sugimoto S, Utsunomiya S, Kagamu H, Aoyama H, Court L, Tokuyama K, Baba R, Ogihara Y, Ichikawa K, Toyama J. Development of a video image-based QA system for the positional accuracy of dynamic tumor tracking irradiation in the Vero4DRT system. Med Phys 42(8):4745, 8/2015. PMID: 26233202.

Sandulache VC, Chen Y, Skinner HD, Lu T, Feng L, Court LE, Myers JN, Meyn RE, Fuller CD, Bankson JA, Lai SY. Acute tumor lactate perturbations as a biomarker of genotoxic stress: development of a biochemical model. Mol Cancer Ther. e-Pub 9/2015. PMID: 26376962.

Fave X, Cook M, Frederick A, Zhang L, Yang J, Fried D, Stingo F, Court L. Preliminary investigation into sources of uncertainty in quantitative imaging features. Comput Med Imaging Graph 44:54-61, 9/2015. e-Pub 5/2015. PMID: 26004695.

Rubinstein AE, Liao Z, Melancon AD, Guindani M, Followill DS, Tailor RC, Hazle JD, Court LE. Technical Note: A Monte Carlo study of magnetic-field-induced radiation dose effects in mice. Med Phys 42(9):5510, 9/2015. PMID: 26328998.

Niedzielski JS, Yang J, Stingo F, Martel MK, Mohan R, Gomez DR, Briere TM, Liao Z, Court LE. Objectively Quantifying Radiation Esophagitis With Novel Computed Tomography-Based Metrics. Int J Radiat Oncol Biol Phys. e-Pub 10/2015. PMID: 26675063.

Zhang Y, Yang J, Zhang L, Court LE, Balter PA, Dong L. Erratum:  "Modeling respiratory motion for reducing motion artifacts in 4D CT images". Med Phys 42(11):6768, 11/2015. PMID: 26520766.

Hunter LA, Chen YP, Zhang L, Matney JE, Choi H, Kry SF, Martel MK, Stingo F, Liao Z, Gomez D, Yang J, Court LE. NSCLC tumor shrinkage prediction using quantitative image features. Comput Med Imaging Graph 49:29-36. e-Pub 11/2015. PMID: 26878137.

Fave X, Mackin D, Yang J, Zhang J, Fried D, Balter P, Followill D, Gomez D, Kyle Jones A, Singo F, Fontenot J, Court L. Can radiomics features be reproducibly measured from CBCT images for patients with non-small cell lung cancer? Medical Physics 42(12):6784-6797, 12/2015. PMID: 26632036.

Yang J, Zhang L, Fave XJ, Fried DV, Stingo FC, Ng CS, Court LE. Uncertainty analysis of quantitative imaging features extracted from contrast-enhanced CT in lung tumors. Comput Med Imaging Graph 48:1-8. e-Pub 12/2015. PMID: 26745258.

McCarroll RE, Rubinstein AE, Kingsley CV, Yang J, Yang P, Court LE. 3D-Printed Small-Animal Immobilizer for Use in Preclinical Radiotherapy. J Am Assoc Lab Anim Sci 54(5):545-8, 2015. PMCID: PMC4587623.

Baron C, Awan MJ, Mohamed ASR, Akel I, Rosenthal DI, Gunn GB, Garden AS, Dyer BA, Court L, Sevak PR, Kocak-Uzel E, Fuller CD. Estimation of daily interfractional larynx residual setup error after isocentric alignment for head and neck radiotherapy:  quality assurance implications for target volume and organs-at-risk margination using daily CT on-rails imaging. Journal of Applied Clinical Medical Physics 16(1):159-169, 2015.

Zhang Y, Nowicka A, Solley TN, Wei C, Parikh A, Court L, Burks JK, Andreeff M, Woodward WA, Dadbin A, Kolonin MG, Lu KH, Klopp AH. Stromal Cells Derived from Visceral and Obese Adipose Tissue Promote Growth of Ovarian Cancers. PLoS One 10(8):e0136361, 2015. e-Pub 8/2015. PMID: 26317219.

Mackin D, Fave X, Zhang L, Fried D, Yang J, Taylor B, Rodriguez-Rivera E, Dodge C, Jones AK, Court L. Measuring Computed Tomography Scanner Variability of Radiomics Features. Invest Radiol. e-Pub 6/2015. PMID: 26115366.

Fave X, Cook M, Frederick A, Zhang L, Yang J, Fried D, Stingo F, Court L. Preliminary investigation into sources of uncertainty in quantitative imaging features. Comput Med Imaging Graph. e-Pub 5/2015. PMID: 26004695.

Scarboro SB, Cody D, Alvarez P, Followill D, Court L, Stingo FC, Zhang D, McNitt-Gray M, Kry SF. Characterization of the nanoDot OSLD dosimeter in CT. Med Phys 42(4):1797, 4/2015. PMCID: PMC4368592.

Mohamed AS, Ruangskul MN, Awan MJ, Baron CA, Kalpathy-Cramer J, Castillo R, Castillo E, Guerrero TM, Kocak-Uzel E, Yang J, Court LE, Kantor ME, Gunn GB, Colen RR, Frank SJ, Garden AS, Rosenthal DI, Fuller CD. Quality assurance assessment of diagnostic and radiation therapy-simulation CT image registration for head and neck radiation therapy: anatomic region of interest-based comparison of rigid and deformable algorithms. Radiology 274(3):752-63, 3/2015. e-Pub 11/2014. PMCID: PMC4358813.

Zhang L, Fried DV, Fave XJ, Hunter LA, Yang J, Court LE. IBEX: an open infrastructure software platform to facilitate collaborative work in radiomics. Med Phys 42(3):1341-53, 3/2015. PMID: 25735289.

Ngwa W, Sajo E, Ngoma T, Bortfeld T, Gierga D, White KB, Akinwande B, Enwerem-Bromson MM, Teboh Forbang R, Winningham TA, Court LE, Odedina FT, Wu R, Makrigiorgos M, Nguyen PL. Potential for information and communication technologies to catalyze global collaborations in radiation oncology. Int J Radiat Oncol Biol Phys 91(2):444-7, 2/2015. PMID: 25636767.

Martin R, Rubinstein A, Ahmad M, Court L, Pan T. Evaluation of intrinsic respiratory signal determination methods for 4D CBCT adapted for mice. Med Phys 42(1):154-64, 1/2015. PMID: 25563256.

2014

Zhang Y, Yang J, Zhang L, Court LE, Gao S, Balter PA, Dong L. Digital Reconstruction of High-Quality Daily 4D Cone-Beam CT Images Using Prior Knowledge of Anatomy and Respiratory Motion. Comput Med Imaging Graph 40:30-8, 3/2015. e-Pub 10/2014. PMID: 25467806.

Palmer J, Yang J, Pan T, Court LE. Motion of the esophagus due to cardiac motion. PLoS One 9(2):e89126, 2014. e-Pub 2/2014. PMCID: PMC3938435.

Koay EJ, Baio FE, Ondari A, Truty MJ, Cristini V, Thomas RM, Chen R, Chatterjee D, Kang Y, Zhang J, Court L, Bhosale PR, Tamm EP, Qayyum A, Crane CH, Javle M, Katz MH, Gottumukkala VN, Rozner MA, Shen H, Lee JE, Wang H, Chen Y, Plunkett W, Abbruzzese JL, Wolff RA, Maitra A, Ferrari M, Varadhachary GR, Fleming JB. Intra-tumoral heterogeneity of gemcitabine delivery and mass transport in human pancreatic cancer. Phys Biol 11(6):065002, 2014. e-Pub 11/2014. PMCID: PMC4266401.

Yang J., Blum R.S., Balter P., Court L. Image Fusion Based on Estimation Theory: Applied to PET/CT for Radiotherapy. Recent Patents on Medical Imaging, 2014.

Sandulache VC, Chen Y, Lee J, Rubinstein A, Ramirez MS, Skinner HD, Walker CM, Williams MD, Tailor R, Court LE, Bankson JA, Lai SY. Evaluation of hyperpolarized [1-¹³C]-pyruvate by magnetic resonance to detect ionizing radiation effects in real time. PLoS One 9(1):e87031, 2014. e-Pub 1/2014. PMCID: PMC3903593.

Yang J., Chu D., Dong L,. Court L. Advantages of Treating Thoracic Cancer Patients in an Upright Position. Practical Radiation Oncology 4(1):e53-e58, 2014. PMID: 24621432.

Pulliam KB, Followill D, Court L, Dong L, Gillin M, Prado K, Kry SF. A six-year review of more than 13,000 patient-specific IMRT QA results from 13 different treatment sites. J Appl Clin Med Phys 15(5):4935, 2014. e-Pub 9/2014. PMID: 25207581.

Fried DV, Tucker SL, Zhou S, Liao Z, Mawlawi O, Ibbott G, Court LE. Prognostic Value and Reproducibility of Pretreatment CT Texture Features in Stage III Non-Small Cell Lung Cancer. Int J Radiat Oncol Biol Phys 90(4):834-42, 11/2014. e-Pub 9/2014. PMCID: PMC4349397.

Yock AD, Rao A, Dong L, Beadle BM, Garden AS, Kudchadker RJ, Court LE. Forecasting longitudinal changes in oropharyngeal tumor morphology throughout the course of head and neck radiation therapy. Med Phys 41(8):081708, 8/2014. PMID: 25086518.

Fave X, Yang J, Carvalho L, Martin R, Pan T, Balter P, Court L. Upright Cone Beam CT Imaging Using the On-Board Imager. Med Phys 41(6):061906, 6/2014. PMID: 24877817.

Christensen EN, Yu HZ, Klopp AH, Tsai JC, Lawyer AA, Court LE, Eifel PJ. Variable impact of intracavitary brachytherapy fractionation schedule on biologically effective dose to organs at risk in patients with cervical cancer. Brachytherapy 13(3):240-9, May-Jun, 5/2014. e-Pub 11/2013. PMID: 24188993.

Yang J, Woodward WA, Reed VK, Strom EA, Perkins GH, Tereffe W, Buchholz TA, Zhang L, Balter P, Court LE, Li XA, Dong L. Statistical Modeling Approach to Quantitative Analysis of Inter-Observer Variability in Breast Contouring. Int J Radiat Oncol Biol Phys 89(1):214-221, 5/2014. e-Pub 3/2014. PMCID: PMC3997068.

Yock AD, Rao A, Dong L, Beadle BM, Garden AS, Kudchadker RJ, Court LE. Predicting oropharyngeal tumor volume throughout the course of radiation therapy from pretreatment computed tomography data using general linear models. Med Phys 41(5):051705, 5/2014. PMID: 24784371.

2013

Yang J, Beadle BM, Garden AS, Gunn B, Rosenthal D, Ang K, Frank S, Williamson R, Balter P, Court L, Dong L. Auto-Segmentation of Low-Risk Clinical Target Volume for Head and Neck Radiation Therapy. Pract Radiat Oncol 4(1):e31-e37, Jan-Feb, 1/2014. e-Pub 5/2013. PMID: 24621429.

Court LE, Tucker SL, Gomez D, Liao Z, Zhang J, Kry S, Dong L, Martel MK. A technique to use CT images for in vivo detection and quantification of the spatial distribution of radiation-induced esophagitis. J Appl Clin Med Phys 14(3):4195, 2013. e-Pub 5/2013. PMID: 23652249.

Hunter LA, Krafft S, Stingo F, Choi H, Martel MK, Kry SF, Court LE. High quality machine-robust image features: Identification in nonsmall cell lung cancer computed tomography images. Med Phys 40(12):121916, 12/2013. PMID: 24320527.

Matney J, Park PC, Bluett J, Chen YP, Liu W, Court LE, Liao Z, Li H, Mohan R. Effects of respiratory motion on passively scattered proton therapy versus intensity modulated photon therapy for stage III lung cancer: are proton plans more sensitive to breathing motion? Int J Radiat Oncol Biol Phys 87(3):576-82, 11/2013. PMCID: PMC3825187.

Mayo C, Conners S, Warren C, Miller R, Court L, Popple R. Demonstration of a software design and statistical analysis methodology with application to patient outcomes data sets. Med Phys 40(11):111718, 11/2013. PMCID: PMC3815052.

Yock AD, Garden AS, Court LE, Beadle BM, Zhang L, Dong L. Anisotropic margin expansions in 6 anatomic directions for oropharyngeal image guided radiation therapy. Int J Radiat Oncol Biol Phys 87(3):596-601, 11/2013. e-Pub 7/2013. PMID: 23906931.

Yang J, Amini A, Williamson R, Zhang L, Zhang Y, Komaki R, Liao Z, Cox J, Welsh J, Court L, Dong L. Automatic Contouring of Brachial Plexus Using a Multi-Atlas Approach for Lung Cancer Radiation Therapy. Pract Radiat Oncol 3(4):e139-e147, Oct-Dec, 10/2013. e-Pub 2/2013. PMID: 24674411.

Park PC, Cheung JP, Zhu XR, Lee AK, Sahoo N, Tucker SL, Liu W, Li H, Mohan R, Court LE, Dong L. Statistical Assessment of Proton Treatment Plans Under Setup and Range Uncertainties. Int J Radiat Oncol Biol Phys 86(5):1007-13, 8/2013. e-Pub 5/2013. PMCID: PMC3755369.

Cheung JP, Park PC, Court LE, Ronald Zhu X, Kudchadker RJ, Frank SJ, Dong L. A novel dose-based positioning method for CT image-guided proton therapy. Med Phys 40(5):051714, 5/2013. PMCID: PMC3651206.

Zhang Y, Yang J, Zhang L, Court LE, Balter PA, Dong L. Modeling respiratory motion for reducing motion artifacts in 4D CT images. Med Phys 40(4):041716, 4/2013. PMID: 23556886.

2012

Chung H, Court L, Lin SH, Kulkarni D, Balter P. Evaluation of dose variation to normal and critical structures for lung hypofractionated stereotactic body radiation therapy. Pract Rad Onc 2(3):e15-e21, 2012.

Neubauer E, Dong L, Followill DS, Garden AS, Court LE, White RA, Kry SF. Assessment of shoulder position variation and its impact on IMRT and VMAT doses for head and neck cancer. Radiat Oncol 7:19, 2012. e-Pub 2/2012. PMCID: PMC3311611.

Gao S., Zhang Y., Yang J., Wang C., Zhang L., Court L., Dong L. A Hybrid Algorithm to Address Ambiguities in Deformable Image Registration for Radiation Therapy. International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 1(2):50-59, 2012.

Park PC, Cheung J, Zhu XR, Sahoo N, Court L, Dong L. Fast range-corrected proton dose approximation method using prior dose distribution. Phys Med Biol 57(11):3555-69, 6/2012. e-Pub 5/2012. PMCID: PMC3388743.

2011

Winey B, Wagar M, Ebe K, Popple R, Lingos T, Sher D, Court L. Effect of Respiratory Trace Shape on Optimal Treatment Martin 38(6):3125-9, 6/2011. PMID: 21815386.

Aristophanous M, Rottmann J, Court LE, Berbeco RI. EPID-guided 3D dose verification of lung SBRT. Med Phys 38(1):495-503, 1/2011. PMID: 21361218.

2010

Court L, Wagar M, Bogdanov M, Ionascu D, Schofield D, Allen A, Berbeco R, Lingos T. Use of reduced dose rate when treating moving tumors using dynamic IMRT. J Appl Clin Med Phys 12(1):3276, 2011. e-Pub 9/2010. PMID: 21330973.

Nikolic B, Khosa F, Lin PJ, Khan AN, Sarwar S, Yam CS, Court LE, Raptopoulos V, Clouse ME. Absorbed radiation dose in radiosensitive organs during coronary CT angiography using 320-MDCT: effect of maximum tube voltage and heart rate variations. AJR Am J Roentgenol 195(6):1347-54, 12/2010. PMID: 21098194.

Court L, Urribarri J, Makrigiorgos M. Carbon fiber couches and skin sparing. J Appl Clin Med Phys 11(2):3241, 2010. e-Pub 4/2010. PMID: 20592705.

Court LE, Seco J, Lu XQ, Ebe K, Mayo C, Ionascu D, Winey B, Giakoumakis N, Aristophanous M, Berbeco R, Rottman J, Bogdanov M, Schofield D, Lingos T. Use of a realistic breathing lung phantom to evaluate dose delivery errors. Med Phys 37(11):5850-7, 11/2010. PMID: 21158297.

Rottmann J, Aristophanous M, Chen A, Court L, Berbeco R. A multi-region algorithm for marklerless beam's-eye view lung tumor tracking. Phys. Med. Biol. 55:5585-5598, 8/2010. PMID: 20808029.

Court L, Wagar M, Berbeco R, Reisner A, Winey B, Schofield D, Ionascu D, Allen AM, Popple R, Lingos T. Evaluation of the interplay effect when using RapidArc to treat targets moving in the craniocaudal or right-left direction. Med Phys 37(1):4-11, 1/2010. PMID: 20175460.

2009

Court LE, Ching D, Schofield D, Czerminska M, Allen AM. Evaluation of the dose calculation accuracy in intensity-modulated radiation therapy for mesothelioma, focusing on low doses to the contralateral lung. J Appl Clin Med Phys 10(2):2850, 2009. e-Pub 4/2009. PMID: 19458589.

Chin DW, Treister N, Friedland B, Cormack RA, Tishler RB, Makrigiorgos GM, Court LE. Effect of dental restorations and prostheses on radiotherapy dose distribution: a Monte Carlo study. J Appl Clin Med Phys 10(1):2853, 2009. e-Pub 2/2009. PMID: 19223833.

2008

Court LE, Tishler R, Xiang H, Allen AM, Makrigiorgos M, Chin L. Experimental evaluation of the accuracy of skin dose calculation for a commercial treatment planning system. J Appl Clin Med Phys 9(1):2792, 2008. PMID: 18449168.

Court LE, Wolfsberger L, Allen AM, James S, Tishler RB. Clinical experience of the importance of daily portal imaging for head and neck IMRT treatments. J Appl Clin Med Phys 9(3):2756, 2008. PMID: 18716586.

Allen AM, Wolfsberger L, Tishler RB, Court LE. Options for combining altered fractionation with IMRT. Technol Cancer Res Treat 7(6):457-61, 12/2008. PMID: 19044325.

Pawlicki T, Yoo S, Court LE, McMillan SK, Rice RK, Russell JD, Pacyniak JM, Woo MK, Basran PS, Shoales J, Boyer AL. Moving from IMRT QA measurements toward independent computer calculations using control charts. Radiother Oncol 89(3):330-7, 12/2008. e-Pub 8/2008. PMID: 18701175.

Caglar HB, Tishler RB, Othus M, Burke E, Li Y, Goguen L, Wirth LJ, Haddad RI, Norris CM, Court LE, Aninno DJ, Posner MR, Allen AM. Dose to larynx predicts for swallowing complications after intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 72(4):1110-8, 11/2008. e-Pub 5/2008. PMID: 18468812.

Pawlicki T, Yoo S, Court LE, McMillan SK, Rice RK, Russell JD, Pacyniak JM, Woo MK, Basran PS, Boyer AL, Bonilla C. Process control analysis of IMRT QA: implications for clinical trials. Phys Med Biol 53(18):5193-205, 9/2008. e-Pub 8/2008. PMID: 18728311.

Court LE, Wagar M, Ionascu D, Berbeco R, Chin L. Management of the interplay effect when using dynamic MLC sequences to treat moving targets. Med Phys 35(5):1926-31, 5/2008. PMID: 18561668.

2007

Song JS, Court LE, Cormack RA. Monte Carlo calculation of rectal dose when using an intrarectal balloon during prostate radiation therapy. Med Dosim 32(3):151-6, 2007. PMID: 17707193.

Zygmanski P, Rosca F, Kadam D, Lovenz F, Nalichowski A, Court L, Chin L,. Determination of depth and field-size dependence of MLC transmission in IMRT beams. J Appl Clin Med Phys 8(4), 2007.

Allen AM, Schofield D, Hacker F, Court LE, Czerminska M. Restricted field IMRT dramatically enhances IMRT planning for mesothelioma. Int J Radiat Oncol Biol Phys 69(5):1587-92, 12/2007. e-Pub 9/2007. PMID: 17892915.

Court LE, Tishler RB. Experimental evaluation of the impact of different head-and-neck intensity-modulated radiation therapy planning techniques on doses to the skin and shallow targets. Int J Radiat Oncol Biol Phys 69(2):607-13, 10/2007. PMID: 17869674.

Court LE, Allen A, Tishler R. Evaluation of the precision of portal-image-guided head-and-neck localization: an intra- and interobserver study. Med Phys 34(7):2704-7, 7/2007. PMID: 17821978.

Xiang HF, Song JS, Chin DW, Cormack RA, Tishler RB, Makrigiorgos GM, Court LE, Chin LM. Build-up and surface dose measurements on phantoms using micro-MOSFET in 6 and 10 MV x-ray beams and comparisons with Monte Carlo calculations. Med Phys 34(4):1266-73, 4/2007. PMID: 17500458.

2006

Court LE, D'Amico AV, Kadam D, Cormack R. Motion and shape change when using an endorectal balloon during prostate radiation therapy. Radiother Oncol 81(2):184-9, 11/2006. e-Pub 10/2006. PMID: 17069915.

Court LE, Jahnke L, Chin D, Song J, Cormack R, Zygmanski P, Tishler RB, Chin L. Dynamic IMRT treatments of sinus region tumors: comparison of Monte Carlo calculations with treatment planning system calculations and ion chamber measurements. Technol Cancer Res Treat 5(5):489-95, 10/2006. PMID: 16981791.

Allen AM, Czerminska M, Jänne PA, Sugarbaker DJ, Bueno R, Harris JR, Court L, Baldini EH. Fatal pneumonitis associated with intensity-modulated radiation therapy for mesothelioma. Int J Radiat Oncol Biol Phys 65(3):640-645, 7/2006. PMID: 16751058.

Court LE, Tishler RB, Petit J, Cormack R, Chin L. Automatic online adaptive radiation therapy techniques for targets with significant shape change: a feasibility study. Phys Med Biol 51(10):2493-501, 5/2006. e-Pub 4/2006. PMID: 16675865.

2005

Gifford KA, Horton JL, Pelloski CE, Jhingran A, Court LE, Mourtada F, Eifel PJ. A three-dimensional computed tomography-assisted Monte Carlo evaluation of ovoid shielding on the dose to the bladder and rectum in intracavitary radiotherapy for cervical cancer. Int J Radiat Oncol Biol Phys 63(2):615-21, 10/2005. PMID: 16168853.

Court LE, Dong L, Lee AK, Cheung R, Bonnen MD, O'Daniel J, Wang H, Mohan R, Kuban D. An automatic CT-guided adaptive radiation therapy technique by online modification of multileaf collimator leaf positions for prostate cancer. Int J Radiat Oncol Biol Phys 62(1):154-63, 5/2005. PMID: 15850916.

2004

Court L, Yamazaki T. A comparison of anti-scatter grids for digital radiography. Brit. J. Radiol. 77:1-3, 2004.

Court L, Yamazaki T. Technical note: a comparison of antiscatter grids for digital radiography. Br J Radiol 77(923):950-2, 11/2004. PMID: 15507421.

Barker JL, Garden AS, Ang KK, O'Daniel JC, Wang H, Court LE, Morrison WH, Rosenthal DI, Chao KS, Tucker SL, Mohan R, Dong L. Quantification of volumetric and geometric changes occurring during fractionated radiotherapy for head-and-neck cancer using an integrated CT/linear accelerator system. Int J Radiat Oncol Biol Phys 59(4):960-70, 7/2004. PMID: 15234029.

Court LE, Dong L, Taylor N, Ballo M, Kitamura K, Lee AK, O'Daniel J, White RA, Cheung R, Kuban D. Evaluation of a contour-alignment technique for CT-guided prostate radiotherapy: an intra- and interobserver study. Int J Radiat Oncol Biol Phys 59(2):412-8, 6/2004. PMID: 15145157.

2003

Kitamura K, Court LE, Dong L. [Comparison of imaging modalities for image-guided radiation therapy (IGRT)]. Nippon Igaku Hoshasen Gakkai Zasshi 63(9):574-8, 11/2003. PMID: 14699867.

Court LE, Dong L. Automatic registration of the prostate for computed-tomography-guided radiotherapy. Med Phys 30(10):2750-7, 10/2003. PMID: 14596313.

Court L, Rosen I, Mohan R, Dong L. Evaluation of mechanical precision and alignment uncertainties for an integrated CT/LINAC system. Med Phys 60(6):1198-1210, 6/2003. PMID: 12852544.