Join Our Lab

Postdoctoral Fellows

The Cascone Lab at the world-renowned UT MD Anderson is seeking one or more highly motivated and ambitious postdoctoral fellows to join a well-funded, dynamic and question-driven research program focused on advancing the science of lung cancer immunology and immunotherapy.

Under the mentorship of Tina Cascone, M.D., Ph.D., a physician-scientist and associate professor with tenure, and director of translational research in the Thoracic/Head and Neck Medical Oncology department, successful candidates will engage in innovative translational research aimed at unraveling the immune-mediated mechanisms of tumor response and resistance to therapy in non-small cell lung cancer.

This fellowship offers a unique and exciting opportunity to contribute to cutting-edge, high-impact projects at the intersection of preclinical discovery and clinical application. Research will involve both state-of-the-art murine models and biospecimens from pioneering clinical trials testing immune checkpoint inhibitors as well as standard-of-care chemoimmunotherapy regimens in patients with surgically resected non-small cell lung cancer.

Key Research Focus

• Mechanistic studies of immune checkpoint blockade in lung cancer
• Analysis of tumor-immune interactions in response and resistance to therapy
• Regulation of systemic and local anti-tumor immunity under therapeutic pressure
• Utilization of syngeneic and genetically engineered mouse models
• Integration of human clinical data with experimental immunology
• Contribution to the development of novel combination strategies and biomarkers

What We Offer

• A collaborative, high-energy environment at a top-ranked cancer center
• Close mentorship from a physician-scientist involved in leading clinical trials
• Access to cutting-edge technologies, including immunogenomics, single-cell and spatial transcriptomics, flow cytometry and immune profiling
• Opportunities for first-author publications, grant development and career advancement
• Competitive salary and comprehensive benefits

Qualifications

• Required:
  • Ph.D., M.D./Ph.D. or equivalent in tumor immunology, molecular biology, cancer biology or related fields
  • Demonstrated experience with immune checkpoint inhibitors, T cell-based therapies or tumor immunology
  • Proficiency in handling and analyzing murine cancer models, particularly syngeneic systems
  • Strong experimental, analytical and communication skills
  • Self-motivated, collaborative and driven to make a scientific impact
• Preferred (but not required)
  • Familiarity with oncogenic signaling, biomarkers of response/resistance or cancer metabolism
  • Experience with multi-omics approaches, such as immunogenomics or transcriptomics
  • Background in evaluating human tumor samples and integrating clinical data

UT MD Anderson is ranked one of the top two hospitals in cancer care nationwide for 25 years by U.S. News & World Report. The cancer center ranks high in the number of National Cancer Institute grants and invests millions in research every year; it offers active graduate and postdoctoral training programs, and the unmatched scientific environment of the Texas Medical Center, the world's largest biomedical center.

Join Us

If you are passionate about translating scientific discovery into therapeutic innovation and thrive in a collaborative, mission-driven research environment, we encourage you to apply.

To Apply:

Please send a cover letter describing your research interests and career goals, a current CV and contact information for at least three references to: TCascone@MDAnderson.org

UT MD Anderson is an equal opportunity employer and does not discriminate on the basis of race, color, national origin, gender, sexual orientation, age, religion, disability or veteran status except where such distinction is required by law. All positions at UT MD Anderson are security sensitive and subject to examination of criminal history record information. Smoke-free and drug-free environment.