Breast surgical oncologists are studying approaches that unleash the immune system against breast cancer. Elizabeth Mittendorf, M.D., Ph.D., is studying vaccines that can stimulate an immune response in breast cancer patients who are disease-free, but are at high risk for recurrence.
The vaccine furthest along is NeuVax. It's being evaluated in an international phase III clinical trial led by Mittendorf. The trial randomized 750 patients to vaccine versus placebo to determine if vaccination reduces recurrence rates.
Less invasive surgery
Breast surgical oncologists are investigating ways to do less surgery with the same outcomes.
Breast surgical oncologist Kelly Hunt, M.D., led a study that showed no significant difference in survival between women undergoing sentinel node surgery alone versus complete axillary node dissection. The study led to a new standard of care for breast cancer patients worldwide. Now, along with breast surgical oncologists Henry Kuerer, M.D., Ph.D., and Abigail Caudle, M.D., they're starting to look at the same paradigm in women with more advanced breast cancers.
Breast surgeon Rosa Hwang, M.D., is studying cryoblation to treat breast cancer.
Breast Cancer Moon Shot™
Triple-negative breast cancer (TNBC) causes almost 12,000 deaths annually. The Breast Cancer Moon Shot™ is an unprecedented effort to dramatically accelerate the pace of converting scientific discoveries into clinical advances that reduce this deadly type of breast cancer.