Randomized trial finds targeting individual metastases in oligometastatic breast cancer does not improve survival
Oligometastatic cancer has spread beyond the original tumor to a limited number of sites Study tested whether treating all visible breast cancer metastases with radiation or surgery improved outcomes beyond standard drug therapy In patients with four or fewer metastases, treating each visible metastatic tumor did not improve progression-free or overall survival Early results from blood tests that look for tumor cells did show...
Personalized support and navigation increased genetic testing of hereditary cancers among immediate family members
Relatives of cancer patients who received guidance and support from navigators were more likely to complete genetic testing for hereditary cancers...
First clinical stage covalent Werner helicase inhibitor shows proof-of-concept in Phase 1 trial
Data from this first-in-human trial of VVD-133214 (formerly RO7589831) prompted further clinical development, including ongoing Phase 1b and...
Researchers suggest tile-based radiation therapy as standard of care to lower risk of recurrence in brain metastases
A type of radiation treatment implanted during surgery (GammaTile) significantly lowers risk of recurrence and may help patients with brain metastases live longer
Tile-based radiation therapy outperformed standard of care for patients with no new side effects in a multicenter Phase 3 trial
Immediate placement of radioactive tiles during surgery significantly lowered recurrences and improved recurrence-free survival and overall survival...
ASTRO: UT MD Anderson highlights advances in radiation oncology
UT MD Anderson faculty will present nearly 70 abstracts at the 2026 ASTRO Annual Meeting
Scientific presentation topics include advances in...
Study identifies two factors that may help patients benefit from off-the-shelf CAR T cell therapies
While approved CAR T cell therapies are made from a patient's own cells, off-the-shelf CAR T cell therapies are manufactured from healthy donor...
AI model uses routine imaging to identify patients at risk for serious treatment-induced lung inflammation
Immunotherapy-induced lung inflammation is a potentially life-threatening condition that occurs in about 10% of lung cancer patients receiving...
Researchers uncover dual role of B7-H3 in tumor immune suppression
Researchers identified a previously unknown pathway for the B7-H3 immune checkpoint that creates a physical defense for prostate tumors
Using...
B cells may help predict risk of colitis from immunotherapy
Colitis, an inflammation of the inner lining of the colon, is a common side effect of immunotherapy that can disrupt treatment
No methods currently...
Fecal microbiota transplantation may improve immunotherapy-related colitis
Immunotherapy-related colitis is a potentially serious side effect of immunotherapy that can force patients to pause cancer treatment ...
Most patients with appendix cancer may avoid chemotherapy after surgery, study suggests
Researchers found fewer than 10% of patients experienced cancer recurrence after surgery
Chemotherapy after surgery was not associated with...
Blood test could monitor bone metastasis in medullary thyroid cancer
Medullary thyroid cancer often spreads to the bone in advanced disease, causing abnormal bone growth
Researchers discovered the OPG protein...
Targeted antibody improves outcomes for patients with advanced lung cancer who have faced treatment resistance
Phase 3 HARMONi study evaluated ivonescimab plus chemotherapy for patients with EGFR-mutant lung cancer whose tumors stopped responding to...
Psilocybin prevents chemotherapy-related nerve injury and associated symptoms in preclinical models
Peripheral neuropathy is a common side effect of chemotherapy treatment, resulting in symptoms that can include numbness, painful nerve injury...
Daraxonrasib demonstrates initial antitumor activity in RAS-mutant lung cancer
Daraxonrasib is a RAS inhibitor from Revolution Medicines that has been approved by the Food & Drug Administration for previously treated...