Researchers uncover dual role of B7-H3 in tumor immune suppression
Researchers identified a previously unknown pathway for the B7-H3 immune checkpoint that creates a physical defense for prostate tumors
Using a therapy to target B7-H3 along with a MEK inhibitor targeting this pathway produced durable antitumor activity in preclinical models of advanced prostate cancer
Findings uncovered a novel biological function of B7-H3 in cancer immunity
Results suggest a combination approach could overcome treatment...
B cells may help predict risk of colitis from immunotherapy
Colitis, an inflammation of the inner lining of the colon, is a common side effect of immunotherapy that can disrupt treatment
No methods currently...
Fecal microbiota transplantation may improve immunotherapy-related colitis
Immunotherapy-related colitis is a potentially serious side effect of immunotherapy that can force patients to pause cancer treatment ...
Most patients with appendix cancer may avoid chemotherapy after surgery, study suggests
Researchers found fewer than 10% of patients experienced cancer recurrence after surgery
Chemotherapy after surgery was not associated with longer survival or lower relapse rates
Certain tumor types and genetic changes helped identify patients at higher risk of recurrence
Most patients with localized appendix cancer may be able to safely avoid chemotherapy after surgery, according to a new study from researchers at The University of...
Blood test could monitor bone metastasis in medullary thyroid cancer
Medullary thyroid cancer often spreads to the bone in advanced disease, causing abnormal bone growth
Researchers discovered the OPG protein...
Targeted antibody improves outcomes for patients with advanced lung cancer who have faced treatment resistance
Phase 3 HARMONi study evaluated ivonescimab plus chemotherapy for patients with EGFR-mutant lung cancer whose tumors stopped responding to...
Psilocybin prevents chemotherapy-related nerve injury and associated symptoms in preclinical models
Peripheral neuropathy is a common side effect of chemotherapy treatment, resulting in symptoms that can include numbness, painful nerve injury...
Daraxonrasib demonstrates initial antitumor activity in RAS-mutant lung cancer
Daraxonrasib is a RAS inhibitor from Revolution Medicines that has been approved by the Food & Drug Administration for previously treated...