Immune cell dysfunction, not absence, defines skin cancer in immunosuppressed patients
Patients with weakened immune systems develop non-melanoma skin cancers that are more frequent, more aggressive, and more often lethal
Study finds these skin cancers are not devoid of immune cells, but the interactions between these cells are failing
The defect localizes to macrophages, which help regulate the antitumor immune response
Understanding the specific immune defects responsible may point...