Proteomics is the study of proteins and proteoforms, including post-translational modifications and sequence variants.
Proteins tend to be stronger biomarkers than DNA and RNA; that is, proteins tend to be more strongly correlated with clinically relevant endpoints.
Mass spectrometry (MS) is our primary technology for label-free proteomics, including bulk and single-cell proteomics.
Current MS technologies can typically measure on the order of 7,000 proteins per sample
The most common biological matrices in which we measure proteins are: cells, media, plasma, whole blood, red blood cells, urine, and tissues.