Proteins are large, complex molecules made up of hundreds or thousands of amino acids. They are required for the structure, function and regulation of biological systems. Proteins catalyze chemical reactions, transport molecules, provide mechanical support, participate in immune protection, regulate cell signaling and control cell growth, differentiation and death. The proteome is the entire set of proteins expressed by a cell, tissue or organism. Each protein-coding gene can give rise to thousands of different proteoforms, including post-translational modifications and sequence variants.
We provide services to identify, quantify and characterize proteins from any biological sample. We offer proteome profiling, targeted quantitation, post-translational modification analysis, protein-protein interactions and more. Our facility, biology team, instrument operator team and data science team support projects across the continuum of drug development and life science research, from exploratory/discovery research to preclinical research to clinical research. We collaborate to ensure that all aspects of experimental design, sample preparation, sample analysis and data interpretation are planned and executed at the highest quality. We serve all academic and non-academic researchers worldwide. Contact us to learn more about our capabilities and how we can support your proteomics project. Learn more about proteomics.
The Proteomics Core Facility guides investigators through the experimental design and statistical considerations of their proteomics studies. Please contact Phil Lorenzi to schedule an appointment to discuss your project.
If you do not have an iLab account, please register (instructions here.)
After you've had a meeting with Phil Lorenzi and after your iLab account is set up, services can be requested through iLab.
The Proteomics Core Facility supports all stages of drug development and life science research (oncology, neuroscience, cardiovascular, aging) and commercial startup efforts. Our combined expertise in mass spectrometry, immunoassays, technology development, and data science including artificial intelligence and machine learning make advanced proteomics technologies accessible, easy to incorporate into your research, and interpretable for maximum impact.
In order to continue obtaining Core support in a challenging environment, it is crucial that our users acknowledge the following grants in all publications. Thank you!
Please use the following text when acknowledging the core: “The Proteomics Facility was supported in part by The University of Texas MD Anderson Cancer Center and NIH grants S10OD012304-01”
Go to the Acknowledgment page to see guidelines on whether the efforts of core personnel merit authorship.
Phil Lorenzi, Ph.D.
Sample Delivery/Shipment Address:
MD Anderson Cancer Center
7435 Fannin Street, Room 2SCR3.3209
Houston, TX 77054