Publications
Selected Publications
Recent publications from the PRIME-TR team:
Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients. Science. 2020 Dec 10;. doi: 10.1126/science.abb5920. [Epub ahead of print] PubMed PMID: 33303685, Baruch EN, Youngster I, Ben-Betzalel G, Ortenberg R, Lahat A, Katz L, Adler K, Dick-Necula D, Raskin S, Bloch N, Rotin D, Anafi L, Avivi C, Melnichenko J, Steinberg-Silman Y, Mamtani R, Harati H, Asher N, Shapira-Frommer R, Brosh-Nissimov T, Eshet Y, Ben-Simon S, Ziv O, Khan MAW, Amit M, Ajami NJ, Barshack I, Schachter J, Wargo JA, Koren O, Markel G, Boursi B.
Gut Microbes' Impact on Oncogenic Drivers: Location Matters. Mol Cell. 2020 Sep 17;79(6):878-880. doi: 10.1016/j.molcel.2020.08.021.PMID: 32946762, White MG, Wargo JA.
Modulating gut microbes. Science. 2020 Sep 11;369(6509):1302-1303. doi: 10.1126/science.abc3965. PMID: 32913089, Wargo JA.
Can we harness the microbiota to enhance the efficacy of cancer immunotherapy?, Nat Rev Immunol. 2020 Sep;20(9):522-528. doi: 10.1038/s41577-020-0374-6. Epub 2020 Jul 13. PMID: 32661409, Finlay BB, Goldszmid R, Honda K, Trinchieri G, Wargo J, Zitvogel L
Gut Microbiome Modulation Via Fecal Microbiota Transplant to Augment Immunotherapy in Patients with Melanoma or Other Cancers, Curr Oncol Rep. 2020 Jun 24;22(7):74. doi: 10.1007/s11912-020-00913-y.PMID: 32577835, McQuade JL, Ologun GO, Arora R, Wargo JA.
Uncovering the role of the gut microbiota in immune checkpoint blockade therapy: A mini-review, Semin Hematol, 2020 Jan;57(1):13-18. doi: 10.1053/j.seminhematol.2020.05.002. Epub 2020 May 19.PMID: 32690139, Halsey T, Ologun G, Wargo J, Jenq RR.
The human tumor microbiome is composed of tumor type-specific intracellular bacteria. Science. 2020 May 29;368(6494):973-980. doi: 10.1126/science.aay9189.PMID: 32467386, Nejman D, Livyatan I, Fuks G, Gavert N, Zwang Y, Geller LT, Rotter-Maskowitz A, Weiser R, Mallel G, Gigi E, Meltser A, Douglas GM, Kamer I, Gopalakrishnan V, Dadosh T, Levin-Zaidman S, Avnet S, Atlan T, Cooper ZA, Arora R, Cogdill AP, Khan MAW, Ologun G, Bussi Y, Weinberger A, Lotan-Pompan M, Golani O, Perry G, Rokah M, Bahar-Shany K, Rozeman EA, Blank CU, Ronai A, Shaoul R, Amit A, Dorfman T, Kremer R, Cohen ZR, Harnof S, Siegal T, Yehuda-Shnaidman E, Gal-Yam EN, Shapira H, Baldini N, Langille MGI, Ben-Nun A, Kaufman B, Nissan A, Golan T, Dadiani M, Levanon K, Bar J, Yust-Katz S, Barshack I, Peeper DS, Raz DJ, Segal E, Wargo JA, Sandbank J, Shental N, Straussman R.
Gut Microbiome Modulates Response to Cancer Immunotherapy. Dig Dis Sci. 2020 Mar;65(3):885-896. doi: 10.1007/s10620-020-06111-x.PMID: 32067144, Khan MAW, Ologun G, Arora R, McQuade JL, Wargo JA.
AI finds microbial signatures in tumours and blood across cancer types. Nature. 2020 Mar;579(7800):502-503. doi: 10.1038/d41586-020-00637-w. PubMed PMID: 32161344, Ajami NJ, Wargo JA.
Recent publications from the PRIME-TR team:
Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients. Science. 2020 Dec 10;. doi: 10.1126/science.abb5920. [Epub ahead of print] PubMed PMID: 33303685, Baruch EN, Youngster I, Ben-Betzalel G, Ortenberg R, Lahat A, Katz L, Adler K, Dick-Necula D, Raskin S, Bloch N, Rotin D, Anafi L, Avivi C, Melnichenko J, Steinberg-Silman Y, Mamtani R, Harati H, Asher N, Shapira-Frommer R, Brosh-Nissimov T, Eshet Y, Ben-Simon S, Ziv O, Khan MAW, Amit M, Ajami NJ, Barshack I, Schachter J, Wargo JA, Koren O, Markel G, Boursi B.
Gut Microbes' Impact on Oncogenic Drivers: Location Matters. Mol Cell. 2020 Sep 17;79(6):878-880. doi: 10.1016/j.molcel.2020.08.021.PMID: 32946762, White MG, Wargo JA.
Modulating gut microbes. Science. 2020 Sep 11;369(6509):1302-1303. doi: 10.1126/science.abc3965. PMID: 32913089, Wargo JA.
Can we harness the microbiota to enhance the efficacy of cancer immunotherapy?, Nat Rev Immunol. 2020 Sep;20(9):522-528. doi: 10.1038/s41577-020-0374-6. Epub 2020 Jul 13. PMID: 32661409, Finlay BB, Goldszmid R, Honda K, Trinchieri G, Wargo J, Zitvogel L
Gut Microbiome Modulation Via Fecal Microbiota Transplant to Augment Immunotherapy in Patients with Melanoma or Other Cancers, Curr Oncol Rep. 2020 Jun 24;22(7):74. doi: 10.1007/s11912-020-00913-y.PMID: 32577835, McQuade JL, Ologun GO, Arora R, Wargo JA.
Uncovering the role of the gut microbiota in immune checkpoint blockade therapy: A mini-review, Semin Hematol, 2020 Jan;57(1):13-18. doi: 10.1053/j.seminhematol.2020.05.002. Epub 2020 May 19.PMID: 32690139, Halsey T, Ologun G, Wargo J, Jenq RR.
The human tumor microbiome is composed of tumor type-specific intracellular bacteria. Science. 2020 May 29;368(6494):973-980. doi: 10.1126/science.aay9189.PMID: 32467386, Nejman D, Livyatan I, Fuks G, Gavert N, Zwang Y, Geller LT, Rotter-Maskowitz A, Weiser R, Mallel G, Gigi E, Meltser A, Douglas GM, Kamer I, Gopalakrishnan V, Dadosh T, Levin-Zaidman S, Avnet S, Atlan T, Cooper ZA, Arora R, Cogdill AP, Khan MAW, Ologun G, Bussi Y, Weinberger A, Lotan-Pompan M, Golani O, Perry G, Rokah M, Bahar-Shany K, Rozeman EA, Blank CU, Ronai A, Shaoul R, Amit A, Dorfman T, Kremer R, Cohen ZR, Harnof S, Siegal T, Yehuda-Shnaidman E, Gal-Yam EN, Shapira H, Baldini N, Langille MGI, Ben-Nun A, Kaufman B, Nissan A, Golan T, Dadiani M, Levanon K, Bar J, Yust-Katz S, Barshack I, Peeper DS, Raz DJ, Segal E, Wargo JA, Sandbank J, Shental N, Straussman R.
Gut Microbiome Modulates Response to Cancer Immunotherapy. Dig Dis Sci. 2020 Mar;65(3):885-896. doi: 10.1007/s10620-020-06111-x.PMID: 32067144, Khan MAW, Ologun G, Arora R, McQuade JL, Wargo JA.
AI finds microbial signatures in tumours and blood across cancer types. Nature. 2020 Mar;579(7800):502-503. doi: 10.1038/d41586-020-00637-w. PubMed PMID: 32161344, Ajami NJ, Wargo JA.
Recent publications from the PRIME-TR team:
Fecal microbiota transplant promotes response in immunotherapy-refractory melanoma patients. Science. 2020 Dec 10;. doi: 10.1126/science.abb5920. [Epub ahead of print] PubMed PMID: 33303685, Baruch EN, Youngster I, Ben-Betzalel G, Ortenberg R, Lahat A, Katz L, Adler K, Dick-Necula D, Raskin S, Bloch N, Rotin D, Anafi L, Avivi C, Melnichenko J, Steinberg-Silman Y, Mamtani R, Harati H, Asher N, Shapira-Frommer R, Brosh-Nissimov T, Eshet Y, Ben-Simon S, Ziv O, Khan MAW, Amit M, Ajami NJ, Barshack I, Schachter J, Wargo JA, Koren O, Markel G, Boursi B.
Gut Microbes' Impact on Oncogenic Drivers: Location Matters. Mol Cell. 2020 Sep 17;79(6):878-880. doi: 10.1016/j.molcel.2020.08.021.PMID: 32946762, White MG, Wargo JA.
Modulating gut microbes. Science. 2020 Sep 11;369(6509):1302-1303. doi: 10.1126/science.abc3965. PMID: 32913089, Wargo JA.
Can we harness the microbiota to enhance the efficacy of cancer immunotherapy?, Nat Rev Immunol. 2020 Sep;20(9):522-528. doi: 10.1038/s41577-020-0374-6. Epub 2020 Jul 13. PMID: 32661409, Finlay BB, Goldszmid R, Honda K, Trinchieri G, Wargo J, Zitvogel L
Gut Microbiome Modulation Via Fecal Microbiota Transplant to Augment Immunotherapy in Patients with Melanoma or Other Cancers, Curr Oncol Rep. 2020 Jun 24;22(7):74. doi: 10.1007/s11912-020-00913-y.PMID: 32577835, McQuade JL, Ologun GO, Arora R, Wargo JA.
Uncovering the role of the gut microbiota in immune checkpoint blockade therapy: A mini-review, Semin Hematol, 2020 Jan;57(1):13-18. doi: 10.1053/j.seminhematol.2020.05.002. Epub 2020 May 19.PMID: 32690139, Halsey T, Ologun G, Wargo J, Jenq RR.
The human tumor microbiome is composed of tumor type-specific intracellular bacteria. Science. 2020 May 29;368(6494):973-980. doi: 10.1126/science.aay9189.PMID: 32467386, Nejman D, Livyatan I, Fuks G, Gavert N, Zwang Y, Geller LT, Rotter-Maskowitz A, Weiser R, Mallel G, Gigi E, Meltser A, Douglas GM, Kamer I, Gopalakrishnan V, Dadosh T, Levin-Zaidman S, Avnet S, Atlan T, Cooper ZA, Arora R, Cogdill AP, Khan MAW, Ologun G, Bussi Y, Weinberger A, Lotan-Pompan M, Golani O, Perry G, Rokah M, Bahar-Shany K, Rozeman EA, Blank CU, Ronai A, Shaoul R, Amit A, Dorfman T, Kremer R, Cohen ZR, Harnof S, Siegal T, Yehuda-Shnaidman E, Gal-Yam EN, Shapira H, Baldini N, Langille MGI, Ben-Nun A, Kaufman B, Nissan A, Golan T, Dadiani M, Levanon K, Bar J, Yust-Katz S, Barshack I, Peeper DS, Raz DJ, Segal E, Wargo JA, Sandbank J, Shental N, Straussman R.
Gut Microbiome Modulates Response to Cancer Immunotherapy. Dig Dis Sci. 2020 Mar;65(3):885-896. doi: 10.1007/s10620-020-06111-x.PMID: 32067144, Khan MAW, Ologun G, Arora R, McQuade JL, Wargo JA.
AI finds microbial signatures in tumours and blood across cancer types. Nature. 2020 Mar;579(7800):502-503. doi: 10.1038/d41586-020-00637-w. PubMed PMID: 32161344, Ajami NJ, Wargo JA.
Blog Posts and Opinion Pieces
May 5, 2020, Oncology Times, Life in the Time of COVID-19, Kantarjian, Hagop MD; Welch, Mary Alma MMSc; Kornblau, Steven MD; DiNardo, Andrew MD; Ajami, Nadim PhD, https://journals.lww.com/oncology-times/Fulltext/2020/05050/Life_in_the_Time_of_COVID_19.2.aspx
April 13, 2020, Baker Institute Blog, LOOKING FOR LIGHT AT THE END OF THE COVID-19 TUNNEL, Hagop Kantarjian, M.D., Mary Alma Welch, Nadim Ajami, Ph.D., http://blog.bakerinstitute.org/2020/04/13/looking-for-light-at-the-end-of-the-covid-19-tunnel/
April 7, 2020, Baker Institute Blog, THE IMPORTANCE OF WIDESPREAD COVID-19 TESTING IN HOUSTON AND THE TEXAS MEDICAL CENTER, Hagop Kantarjian, M.D., Nadim Ajami, Ph.D., Andrew DiNardo, M.D., https://blog.bakerinstitute.org/2020/04/07/the-importance-of-widespread-covid-19-testing-in-houston-and-the-texas-medical-center/
May 5, 2020, Oncology Times, Life in the Time of COVID-19, Kantarjian, Hagop MD; Welch, Mary Alma MMSc; Kornblau, Steven MD; DiNardo, Andrew MD; Ajami, Nadim PhD, https://journals.lww.com/oncology-times/Fulltext/2020/05050/Life_in_the_Time_of_COVID_19.2.aspx
April 13, 2020, Baker Institute Blog, LOOKING FOR LIGHT AT THE END OF THE COVID-19 TUNNEL, Hagop Kantarjian, M.D., Mary Alma Welch, Nadim Ajami, Ph.D., http://blog.bakerinstitute.org/2020/04/13/looking-for-light-at-the-end-of-the-covid-19-tunnel/
April 7, 2020, Baker Institute Blog, THE IMPORTANCE OF WIDESPREAD COVID-19 TESTING IN HOUSTON AND THE TEXAS MEDICAL CENTER, Hagop Kantarjian, M.D., Nadim Ajami, Ph.D., Andrew DiNardo, M.D., https://blog.bakerinstitute.org/2020/04/07/the-importance-of-widespread-covid-19-testing-in-houston-and-the-texas-medical-center/
May 5, 2020, Oncology Times, Life in the Time of COVID-19, Kantarjian, Hagop MD; Welch, Mary Alma MMSc; Kornblau, Steven MD; DiNardo, Andrew MD; Ajami, Nadim PhD, https://journals.lww.com/oncology-times/Fulltext/2020/05050/Life_in_the_Time_of_COVID_19.2.aspx
April 13, 2020, Baker Institute Blog, LOOKING FOR LIGHT AT THE END OF THE COVID-19 TUNNEL, Hagop Kantarjian, M.D., Mary Alma Welch, Nadim Ajami, Ph.D., http://blog.bakerinstitute.org/2020/04/13/looking-for-light-at-the-end-of-the-covid-19-tunnel/
April 7, 2020, Baker Institute Blog, THE IMPORTANCE OF WIDESPREAD COVID-19 TESTING IN HOUSTON AND THE TEXAS MEDICAL CENTER, Hagop Kantarjian, M.D., Nadim Ajami, Ph.D., Andrew DiNardo, M.D., https://blog.bakerinstitute.org/2020/04/07/the-importance-of-widespread-covid-19-testing-in-houston-and-the-texas-medical-center/
May 5, 2020, Oncology Times, Life in the Time of COVID-19, Kantarjian, Hagop MD; Welch, Mary Alma MMSc; Kornblau, Steven MD; DiNardo, Andrew MD; Ajami, Nadim PhD, https://journals.lww.com/oncology-times/Fulltext/2020/05050/Life_in_the_Time_of_COVID_19.2.aspx
April 13, 2020, Baker Institute Blog, LOOKING FOR LIGHT AT THE END OF THE COVID-19 TUNNEL, Hagop Kantarjian, M.D., Mary Alma Welch, Nadim Ajami, Ph.D., http://blog.bakerinstitute.org/2020/04/13/looking-for-light-at-the-end-of-the-covid-19-tunnel/
April 7, 2020, Baker Institute Blog, THE IMPORTANCE OF WIDESPREAD COVID-19 TESTING IN HOUSTON AND THE TEXAS MEDICAL CENTER, Hagop Kantarjian, M.D., Nadim Ajami, Ph.D., Andrew DiNardo, M.D., https://blog.bakerinstitute.org/2020/04/07/the-importance-of-widespread-covid-19-testing-in-houston-and-the-texas-medical-center/
May 5, 2020, Oncology Times, Life in the Time of COVID-19, Kantarjian, Hagop MD; Welch, Mary Alma MMSc; Kornblau, Steven MD; DiNardo, Andrew MD; Ajami, Nadim PhD, https://journals.lww.com/oncology-times/Fulltext/2020/05050/Life_in_the_Time_of_COVID_19.2.aspx
April 13, 2020, Baker Institute Blog, LOOKING FOR LIGHT AT THE END OF THE COVID-19 TUNNEL, Hagop Kantarjian, M.D., Mary Alma Welch, Nadim Ajami, Ph.D., http://blog.bakerinstitute.org/2020/04/13/looking-for-light-at-the-end-of-the-covid-19-tunnel/
April 7, 2020, Baker Institute Blog, THE IMPORTANCE OF WIDESPREAD COVID-19 TESTING IN HOUSTON AND THE TEXAS MEDICAL CENTER, Hagop Kantarjian, M.D., Nadim Ajami, Ph.D., Andrew DiNardo, M.D., https://blog.bakerinstitute.org/2020/04/07/the-importance-of-widespread-covid-19-testing-in-houston-and-the-texas-medical-center/