High-fiber diets and immunotherapy response
Platform for Innovative Microbiome and Translational Research
Jennifer Wargo, M.D., MMSc
PRIME-TR Director
Nadim Ajami, Ph.D.
Executive Director for Scientific Research
- Departments, Labs and Institutes
- Research Centers and Programs
- Platform for Innovative Microbiome and Translational Research (PRIME-TR)
PRIME-TR aims to position MD Anderson as a pioneer in transforming cancer therapy through the modulation of the human microbiome.
PRIME-TR aims to position MD Anderson as a pioneer in transforming cancer therapy through the modulation of the human microbiome.
The Platform for Innovative Microbiome and Translational Research (PRIME-TR) seeks to apply microbiome-based applications as a complement to cancer treatments and prevention methods.
The collection of microbes living in and on the human body, collectively known as the microbiome, can impact cancer development, progression and response to therapy in ways that are not fully understood. Additionally, factors that impact the microbiome, such as diet or therapeutic regimen, can have a downstream effect on how the person’s immune system continues to respond to disease. Clarifying interactions between the microbiome, patient and environmental factors provides an opportunity to improve cancer treatment strategies, but requires a multi-faceted research approach.
PRIME-TR strives to do so by building a robust framework that enables a concerted effort for translational research by leveraging existing resources at our institution and by developing programs and relationships to enable and support high-impact, microbiome-based profiling and interventional trials. The ultimate goal is to improve prevention, diagnosis and treatment strategies for cancer patients and the at-risk population.
News & Media
-
August 29, 2025
What You Should Know About Burned Foods and Cancer Risk Opens a new window
The Washington Post
-
August 26, 2025
Probiotic Supplements Won't Help Certain Types of People. Are You One of Them? Opens a new window
National Geographic
-
October 6, 2023
Jennifer Wargo, M.D., Elected to the National Academy of Medicine
Press Release
-
April 19, 2023
Fecal Microbiota Transplants: 10 Questions, Answered
MD Anderson Cancer Center
-
February 15, 2023
MD Anderson Team Using Poop to Develop Cancer Treatment Opens a new window
Houston Chronicle
-
February 1, 2023
MD Anderson and Federation Bio Announce Collaboration to Develop Novel Microbiome Treatment
Press Release
-
January 17, 2022
MD Anderson’s Jennifer Wargo Receives TAMEST O’Donnell Award for Pioneering Microbiome Research
MD Anderson Cancer Center
-
September 26, 2022
Mighty Bugs: Your Gut Microbes Can Help Fight Cancer, New Research Reveals Opens a new window
Inverse.com
-
January 13, 2022
The PQI Podcast (Season 2, Episode 1): "Cancer and the Microbiome" Opens a new window
The National Community Oncology Dispensing Association (NCODA)
-
August 10, 2020
Over $1 Million Awarded to MD Anderson Cancer Center for Transformative Translational Research Opens a new window
The Mark Foundation for Cancer Research
Contact
Email: primetr@mdanderson.org
Jennifer Wargo, M.D., M.M.Sc.
PRIME-TR Director
Nadim Ajami, Ph.D.
Executive Director for Scientific Research
Jillian Losh, Ph.D.
Scientific Project Director