Research Publications
Patient Mosaic has enabled a wide array of research; see the publications and datasets generated from this effort.
Patient Mosaic has enabled a wide array of research; see the publications and datasets generated from this effort.
2025
Nejla Ozirmak Lermi, Max Molina Ayala, Sharia Hernandez, Wei Lu, Khaja Khan, Alejandra Serrano, Idania Lubo, Leticia Hamana, Katarzyna Tomczak, Sean Barnes, Jinzhuang Dou, Qingnan Liang, RTI Team, Maria Gabriela Raso, Ximing Tang, Mei Jiang, Beatriz Sanchez-Espiridion, Annikka Weissferdt, John Heymach, Jianjun Zhang, Boris Sepesi, Tina Cascone, Anne Tsao, Mehmet Altan, Reza Mehran, Don Gibbons, Ignacio Wistuba, Cara Haymaker, Ken Chen & Luisa M. Solis Soto, Comparison of imaging based single-cell resolution spatial transcriptomics profiling platforms using formalin-fixed paraffin-embedded tumor samples, Nature Communications, 09/26/2025, PMC12474935, 10.1038/s41467-025-63414-1
Pingjun Chen, Maria E. Salvatierra, Alejandra Serrano, Karina Pinao Gonzalez, Sara Ranjbar, Yasin Shokrollahi, Tanishq Gautam, B. Leticia Rodriguez, Patient Mosaic Team, Xiaoxi Pan, Luisa M. Solis Soto and Yinyin Yuan, Optimizing cell recognition in sarcoma multiplex immunohistochemistry images via pre-training strategies, International Symposium on Biomedical Imaging 2025, 06/12/2025, Manuscript 1571073780
Research Areas: Analytical Tools Development
Florentia Dimitriou, Ashish Damania, Priyadharsini Nagarajan, Sabitha Prabhakaran, Pranoti Sahasrabhojane, Yasmine Hoballah, Devarati Mitra, Roi Weiser, Shirley Y. Su, Ehab Y. Hanna, Bita Esmaeli, Travis T. Sims, Curtis Alvin Pettaway, Rodabe Navroze Amaria, Isabella Claudia Glitza, Nadim J. Ajami, Scott Eric Woodman, Jennifer Ann Wargo, Phillip Andrew Futreal, Jennifer Leigh McQuade, Delineating the role of the microbiome and tumor microenvironment interactions driving mucosal melanoma (MM) response and resistance to immune checkpoint inhibitor (ICI) treatment, American Society of Clinical Oncology 2025, 05/30/2025, Abstract 9561, doi: 10.1200/JCO.2025.43.16_suppl.9561
Research Areas: Mucosal Melanoma, Microbiome
Fen Saj, Ashish Damania, Yasmine Hoballah, Pranoti Sahasrabhojane, Patient Mosaic Team, Felicity Namayanja, Quentin Kimana, Lianchun Xiao, Huda Elmehily, Sunyoung Lee, Zishuo Hu, Shubham Pant, Madhulika Eluri, Manal Hassan, Jennifer Wargo, Sabitha Prabhakaran, Milind Javle, Nadim Ajami, Association of gut microbiota with therapy efficacy and prognosis in biliary tract cancer, American Society of Clinical Oncology 2025, 05/22/2025, Abstract 4111, doi: 10.1200/JCO.2025.43.16_suppl.4111
Research Areas: Biliary Tract Cancer, Microbiome
Rosalba Minelli, Luigi Perelli, Benjamin J. Bivona, Sanjana Srinivasan, Desiree Catania, Bianca E. Amador, Frederick S. Robinson, Johnathon L. Rose, Christopher J. Terranova, Alejandro Hernandez Martinez, Charles E. Deckard, Courtney Le, Kuo-Shun Hsu, Michael Peoples, Aparna Subramaniam, Hannah C. Beird, Ningping Feng, Joseph R. Daniele, Christopher Vellano, Joseph Marszalek, Vinod Ravi, Alexander J. Lazar, Andrew Futreal, Timothy P. Heffernan, Giannicola Genovese, Virginia Giuliani, Development of advanced preclinical models for an in-depth characterization of cardiac angiosarcoma, American Association for Cancer Research 2025, 04/25/2025, Abstract 5167, doi: 10.1158/1538-7445.AM2025-5167
Research Areas: Model Development, Cardiac Angiosarcoma
Yasin Shokrollahi, Tanishq Gautam, Alejandra Serrano, Simon P. Castillo, Pingjun Chen, Karina Pinao, Maria Esther Salvatierra, B. Leticia Rodriguez, Patient Mosaic Team, Luisa M. Solis Soto, Yinyin Yuan, Xiaoxi Pan, Artificial intelligence for predicting spatial proteomics using high-plex digital spatial profiling in carcinomas, American Association for Cancer Research 2025, 04/25/2025, Abstract 2428, doi: 10.1158/1538-7445.AM2025-2428
Research Areas: Analytical Tools Development
Pingjun Chen, Alejandra Serrano, Tanishq Gautam, Sara Ranjbar, B. Leticia Rodriguez, Patient Mosaic Team, Luisa M. Solis Soto, Yinyin Yuan, Slide-level foundation models exhibit effective diagnostic and prognostic performance in H&E-stained histopathology, American Association for Cancer Research 2025, 04/25/2025, Abstract 2450, doi: 10.1158/1538-7445.AM2025-2450
Research Areas: Analytical Tools Development
Kyung Serk Cho, Yunhe Liu, Guangsheng Pei, Jianfeng Chen, Tieling Zhou, Khalida M. Wani, Alejandra G. Serrano, Sharia D. Hernandez, Akshaya S. Jadhav, Daiwei Zhang, Hannah C. Beird, Jiahui Jiang, Diana Shamsutdinova, Xinmiao Yan, Yibo Dai, Enyu Dai, Ashley L. Wilson, Anne Waldrep, Fuduan Peng, Wei Lu, Yang Liu, Jimin Min, Paola A. Guerrero, Idania C. Julio, Tong Yin, Shin Hsu Shi, Sabitha Prabhakaran, Scott E. Kopetz, Dipen M. Maru, Alexander Lazar, Amir A. Jazaeri, Michael Green, Mingyao Li, Catherine Sautes-Fridman, Wolf H. Fridman, Andrew Futreal, Luisa M. Soto, Humam Kadara, Anirban Maitra, Suet Yi Leung, Jianjun Gao, Linghua Wang, Pan-cancer spatial characterization of tertiary lymphoid structures, American Association for Cancer Research 2025, 04/15/2025, Abstract 3962, doi: 10.1158/1538-7445.AM2025-3962
Research Areas: Pan-Cancer
Li Zhao, Ying Zhu, Randy Chu, Haifeng Zhu, Yuntao Yang, Chunjie Jiang, Mark Knafl, Xingzhi Song, Xiaogang Wu, Jianhua Zhang, Sabitha Prabhakaran, Scott Woodman, Timothy Heffernan, Elizabeth Burton, Rare Tumor Initiative Team, Andy Futreal, Bissan Al-Lazikani, Identifying molecular vulnerabilities in rare cancers using a novel graph-based therapeutic discovery model, American Association for Cancer Research 2025, 04/15/2025, Abstract 7461, doi: 10.1158/1538-7445.AM2025-7461
Research Areas: Analytical Tools Development, Therapeutics Discovery
Priya Nagarajan, Mark Knafl, Sharia Hernandez, Luisa Solis Soto, Mei Jiang,Scott Woodman, Pavandeep Gill, Michael Tetzlaff, Edwin Parra Cuentas, Bita Esmaeli, Conjunctival Melanoma: Correlation of Clinicopathologic Features and Tumor-Infiltrating Inflammatory Cells, United States and Canadian Academy of Pathology, 03/25/2025, Abstract 1529, doi: 10.1016/j.labinv.2024.103770
Research Areas: Conjunctival Melanoma
Tanishq Gautam, Karina Pinao, Pooja Shukla, Alex Lau, Caner Ercan, B. Leticia Rodriguez, Xiaoxi Pan, Lawrence Kwong, Pingjun Chen, Yinyin Yuan, Simon Castillo, AI-STORM- AI-guided Sampling Tissues for Optimal Representative Morphology, United States and Canadian Academy of Pathology, 03/22/2025, Abstract 1354, doi: 10.1016/j.labinv.2024.103592
Research Areas: Analytical Tools Development
Van K. Morris, Suyu Liu, Kangyu Lin, Haifeng Zhu, Seema Prasad, Armeen Mahvash, Priya Bhosale, Baohua Sun, Edwin R. Parra, Ignacio Wistuba, Arjun Peddireddy, James Yao, Julia Mendoza-Perez, Mark Knafl, Scott E. Woodman, Cathy Eng, Daniel Halperin, Phase II trial of atezolizumab and bevacizumab for treatment of HPV-positive unresectable or metastatic squamous cell carcinoma of the anal canal, Clinical Cancer Research, 02/28/2025, PMID 40019482, doi: 10.1158/1078-0432.CCR-24-1512
Research Areas: HPV-positive Squamous Cell Carcinoma of the anal canal
2024
Xiaoping Wang, Li Zhao, Xingzhi Song, Xiaogang Wu, Savitri Krishnamurthy, Takashi Semba, Shan Shao, Mark Knafl, Larry Coffer II, Angela Alexander, Anita Vines, Swetha Bopparaju, Wendy A. Woodward, Randy Chu, Jianhua Zhang, Clinton Yam, Lenora Loo, Azadeh Nasrazadani, Scott Woodman, Andrew Futreal, Debu Tripathy, Genomic and transcriptomic analyses identify distinctive features of triple-negative inflammatory breast cancer, npj Precision Oncology, 11/18/2024, PMC11574056, doi: 10.1038/s41698-024-00729-0
Research Areas: Inflammatory Breast Cancer
Ayse A Koksoy, Jacqueline Oliva, Katarzyna Tomczak, Michael D Stanford, Nathaniel Deboever, Renganayaki Pandurengan, Marina N Medina Rosales, Nejla Ozirmak Lermi, Chad Strange, Edwin R Parra, Annikka Weissferdt, Ken Chen, David C Rice, Jianjun Zhang, Luisa M Solis Soto, Boris Sepesi, Reza J Mehran, Mehmet Altan, Anne Tsao, Cara L Haymaker, Analysis of PD1+ T cells and lymphoid structure(TLS) presence in pleural mesothelioma using spatial and machine learning approaches, Journal for ImmunoTherapy of Cancer, 11/05/2024, Abstract 1219, doi: 10.1136/jitc-2024-SITC2024.1219
Research Areas: Plural Mesothelioma
Idania Lubo, Wei Lu, Sharia D Hernandez, Khaja Khan, Ximing Tang, Junya Fujimoto, Edwin R Parra, Jacqueline Oliva, Katarzyna Tomczak, Michael D Stanford, Ayse A Koksoy, Marina N Medina Rosales, Nejla Ozirmak Lermi, Maria Gabriela Raso, Stephanie T Schmidt, Carmen Behrens, John V Heymach, Jianjun Zhang, Boris Sepesi, Annikka Weissferdt, David C Rice, Reza J Mehran, Mehmet Altan, Anne Tsao, Tina Cascone, Don L Gibbons, Ken Chen, Ignacio I Wistuba, Cara L Haymaker, and Luisa M Solis Soto., Utilization of a tissue-based PD1_PD-L1 in situ proximity ligation assay in lung adenocarcinoma (LUAD) and pleural mesothelioma, Society for Immunotherapy of Cancer 2024, 11/05/2024, Abstract 115, doi: 10.1136/jitc-2024-SITC2024.0115
Research Areas: Pleural Mesothelioma, Lung Adenocarcinoma, Analytical Tools Development
Katarzyna Tomczak, Nejla Ozirmak Lermi, Nathaniel Deboever, Shumin Li, Sevinj Isgandarova, Michael D Stanford, Carlos Ramos, Jacqueline Oliva, Marina Nayeli Medina Rosales, Ayse A Koksoy, Chang-Jiun Wu, Chad Strange, Annikka Weissferdt, Ken Chen, David C Rice, Reza J Mehran, Jianjun Zhang, Boris Sepesi, Mehmet Altan, Anne Tsao, and Cara L Haymaker, An integrated tumor, immune and genetic landscape of pleural mesothelioma to unleash effective immunotherapy avenues, Society for Immunotherapy of Cancer 2024, 11/05/2024, Abstract 1413, doi: 10.1136/jitc-2024-SITC2024.1413
Research Areas: Pleural Mesothelioma
Jacqueline Oliva, Katarzyna Tomczak, Michael D Stanford, Hsinyi Lu, Nathaniel Deboever, Shumin Li, Marina Nayeli Medina Rosales, Ayse A Koksoy, Nejla Ozirmak Lermi, Chad Strange, Annikka Weissferdt, Ken Chen, David C Rice, Jianjun Zhang, Reza J Mehran, Mehmet Altan, Anne Tsao, Boris Sepesi, Cara L Haymaker, Functional and transcriptomic evaluation of pleural mesothelioma tumor expanded infiltrating lymphocytes and their TCR repertoire, Society for Immunotherapy of Cancer 2024, 11/05/2024, Abstract 456, doi: 10.1136/jitc-2024-SITC2024.0456
Research Areas: Pleural Mesothelioma
Florentia Dimitriou, Ashish V Damania, Priyadharsini Nagarajan, Sabitha Prabhakaran, Neus Bota, Randy Chu, Pranoti Sahasrabhojane, Yasmine Hoballah, Devarati Mitra, Roi Weiser, Shirley Y Su, Bita Esmaeli, Travis T Sims, Curtis A Pettaway, Rodabe N Amaria, Isabella C Glitza, Jillian Losh, Nadim J Ajami, Scott Woodman, Jennifer A Wargo, P. Andrew Futreal, Jennifer McQuade, Delineating the role of the microbiome and tumor microenvironment interactions driving mucosal melanoma response and resistance to immune checkpoint inhibitor treatment, Society for Immunotherapy of Cancer 2024, 11/05/2024, Abstract 1256, doi: 10.1136/jitc-2024-SITC2024.1256
Research Areas: Mucosal Melanoma, Microbiome
Maria E Cabanillas, Ramona Dadu, Renata Ferrarotto, Maria Gule-Monroe, Suyu Liu, Bryan Fellman, Michelle D Williams, Mark Zafereo, Jennifer R Wang, Charles Lu, Matthew Ning, Brian A McKinley, Scott E Woodman, Dzifa Duose, Gary B Gunn, Naifa L Busaidy, Rare Tumor Initiative Team, Anti–Programmed Death Ligand 1 Plus Targeted Therapy in Anaplastic Thyroid Carcinoma, JAMA Oncology, 10/24/2024, PMC11581602, doi: 10.1001/jamaoncol.2024.4729
Research Areas: Anaplastic Thyroid Carcinoma
Tanishq Gautam, Yasin Shokrollahi, Sara Ranjbar, Pingjun Chen, Letty Rodriguez, Simon Castillo, Xiaoxi Pan, Yinyin Yuan, Luisa M. Solis Soto MD, Karina B Pinao Gonzales MD, Maria Esther Salvatierra MD, Alejandra G. Serrano MD, Patient Mosaic Team, Immune-guided AI for Reproducible ROI Detection in Immunofluorescence Pathology, 27th International Conference on Medical Image Computing and Computer Assisted Intervention, 10/06/2024, Paper 3757, doi: 10.1007/978-3-031-72083-3_21
Research Areas: Analytical Tools Development
Florentia Dimitriou, Ashish Damania, Priyadharsini Nagarajan, Sabitha Prabhakaran, Neus Bota, Mark Knafl, Randy A. Chu, Pranoti Sahasrabhojane, Yasmine M. Hoballah, Devarati Mitra, Roi Weiser, Shirley Y. Su, Ehab Y. Hanna, Bita Esmaeli, Travis T. Sims, Curtis A. Pettaway, Rodabe Amaria, Isabella C. Glitza, Tim P. Heffernan, Virginia Giuliani, Christopher P. Vellano, Jillian S. Losh, Nadim J. Ajami, Scott E. Woodman, Jennifer A. Wargo, Andrew Futreal, Jennifer McQuade, Delineating germline, molecular and microbiome factors driving mucosal melanoma risk and immunotherapy response, 21st International Congress of the Society for Melanoma Research, 10/01/2024, Poster e13218, doi: 10.1111/pcmr.13218
Research Areas: Mucosal Melanoma, Analytical Tools Development
Ahmad Abubaker, Zoey Neale, Yasmine Hoballah, Patient Mosaic Team, Facilitating Anaplastic thyroid cancer Specialized Treatment Consortium, Jennifer Wargo, Stephen Lai, Nadim Ajami, Anastasios Maniakas, Clinical Implications of the gut microbiome in anaplastic thyroid cancer, European Thyroid Association, 09/02/2024, Volume 101 OP-06-06, doi: 10.1530/endoabs.101.OP-06-06
Research Areas: Anaplastic Thyroid, Microbiome
Yasin Shokrollahi, Karina Pinao Gonzales, Maria Esther Salvatierra, Tanishq Gautam, Pingjun Chen, Simon Castillo, Patient Mosaic Team, Luisa Solis Soto, Yinyin Yuan, Xiaoxi Pan, Advancing Multiplex Immunofluorescence Imaging Cell Detection using a Semi-Supervised Approach with Pseudo-Labeling, Medical Imaging with Deep Learning 2024, 07/01/2024, Article #184
Research Areas: Analytical Tools Development
Sarah Hamidi, Ramona Dadu, Renata Ferrarotto, Maria Gule-Monroe, Suyu Liu, Bryan M. Fellman, Michelle D. Williams, Mark E. Zafereo, Rui Jennifer Wang, Charles Lu, Matthew S. Ning, Brian McKinley, Scott Eric Woodman, Dzifa Yawa Duose, Gary Brandon Gunn, Naifa Lamki Busaidy, Maria E. Cabanillas, Atezolizumab Plus Taxane Chemotherapy for the Treatment of Non-BRAF, Non-RAS Mutated Anaplastic Thyroid Carcinoma: Final Analysis, American Society of Clinical Oncology 2024, 05/29/2024, Abstract e18070, doi: 10.1200/JCO.2024.42.16_suppl.e18070
Research Areas: Anaplastic Thyroid Carcinoma
Sarah Hamidi, Ramona Dadu, Naifa Lamki Busaidy, Renata Ferrarotto, Maria Gule-Monroe, Suyu Liu, Bryan M. Fellman, Michelle D. Williams, Mark E. Zafereo, Rui Jennifer Wang, Charles Lu, Matthew S. Ning, Brian McKinley, Scott Eric Woodman, Dzifa Yawa Duose, Maria E. Cabanillas, Gary Brandon Gunn, Cobimetinib plus Atezolizumab for RAS and NF1/2-mutated Poorly Differentiated Thyroid Carcinoma, American Society of Clinical Oncology 2024, 05/29/2024, Abstract 6106, doi: 10.1200/JCO.2024.42.16_suppl.6106
Research Areas: Pooly Differentiated Thyroid Carcinoma
Nicholas J. Hornstein, Mohammad A. Zeineddine, Betul B. Gunes, Andrew J. Pellatt, Mark Knafl, Haifeng Zhu, Anneleis F. Willett, Abdelrahman Yousef, Suyu Liu, Ryan Sun, Andrew Futreal, Scott E. Woodman, Melissa W. Taggart, Michael J. Overman, Daniel M. Halperin, Kanwal P. Raghav, John Paul Shen, Efficacy and Safety of Atezolizumab and Bevacizumab in Appendiceal Adenocarcinoma, Cancer Research Communications, 05/29/2024, PMC11135244, doi: 10.1158/2767-9764.CRC-24-0019
Research Areas: Appendiceal Adenocarcinoma
Afsaneh Amouzegar, Xiaogang Wu, James Long, Justin W. Wong, Sabitha Prabhakaran, Latasha Little, Curtis Gumbs, Jared Malke, Julie Simon, Jianhua Zhang, Jennifer Wargo, Priyadharsini Nagarajan, Paul Scheet, Jennifer L. McQuade, Andrew Futreal, The Genetic Risk Architecture of Mucosal Melanoma, American Society of Clinical Oncology 2024, 05/29/2024, Abstract 10595, doi: 10.1200/JCO.2024.42.16_suppl.10595
Research Areas: Mucosal Melanoma
Alicia A. Gingrich, Hannah Beird, Rossana Lazcano, Ryan Denu, Michael Nakazawa, Rare Tumor Initiative Team, Patient Mosaic Team, Ravin Ratan, J. Andrew Livingston, M Alex Zarzour, Anthony Conley, Neeta Somaiah, Dejka Araujo, Shreyaskumar Patel, Christina L. Roland, P. Andrew Futreal, Alexander J. Lazar, Emily Z. Keung, Elise F Nassif Haddad, Immune infiltrate analysis to reveal distinct immune classes for leiomyosarcomas, ASCO 2024, 05/29/2024, Abstract 11546, doi: 10.1200/JCO.2024.42.16_suppl.11546
Research Areas: Leiomyosarcoma
Luana Guimaraes de Sousa, Suyu Liu, Priya Bhosale, Mehmet Altan, Walter Darbonne, Katja Schulze, Shannon Dervin, Cindy Yun, Armeen Mahvash, Anuj Verma, Andrew Futreal, Swati Gite, Edwin Parra Cuentas, Woo Cho, Ignatio Wistuba, James Yao, Scott Woodman, Daniel Halperin, Renata Ferrarotto, Atezolizumab plus bevacizumab in advanced Merkel cell carcinoma: A prospective study, Oral Oncology, 04/24/2024, PMID 38460288, doi: 10.1016/j.oraloncology.2024.106747
Research Areas: Merkel Cell Carcinoma
Afsaneh Amouzegar, Xiaogang Wu, James Long, Sabitha Prabhakaran, Latasha Little, Curtis Gumbs, Jared Malke, Julie Simon, Jianhua Zhang, Jennifer Wargo, Paul Scheet, Justin W. Wong, Priyadharsini Nagarajan, Jennifer L. McQuade, Andrew Futreal, Germline mutations in cancer susceptibility genes in patients with mucosal melanoma, American Association for Cancer Research 2024, 04/05/2024, Abstract 7334, doi: 10.1158/1538-7445.AM2024-7334
Research Areas: Mucosal Melanoma
Florentia Dimitriou, Priyadharsini Nagarajan, Sabitha Prabhakaran, Neus Bota, Mark Knafl, Randy Chu, Ashish Damania, Pranoti V Sahasrabhojane, Yasmine Hoballah, Jillian Losh, Nadim J Ajami, Scott E Woodman, Jennifer A Wargo, Andrew Futreal, Jennifer L McQuade, Delineating germline, tumor and extrinsic factors driving mucosal melanoma (MM) risk and response to immune checkpoint inhibitor (ICI) treatment, American Association for Cancer Research 2024, 04/05/2024, Abstract 6699, doi: 10.1158/1538-7445.AM2024-6699
Research Areas: Mucosal Melanoma, Microbiome
Ayabe RI, Seo YD, Fields BC, Witt RG, Chelvanambi M, Lazcano R, Wani K, Cass S, Johnson S, Hudgens C, Hernandez SD, Halperin DM, Lazar AJ, Wargo JA, Estrella JS, Maxwell JE, Cancer Testis Antigen Expression Correlates With Stromal Natural Killer Cell Activation and Longer Overall Survival in Small Bowel Neuroendocrine Tumors, American Association for Cancer Research Annual Meeting, 04/01/2024, Abstract 3574, doi: 10.1158/1538-7445.AM2024-3574
Research Areas: Small Bowel Neuroendocrine Tumors
Shalini Makawita, Sunyoung Lee, Elisabeth Kong, Lawrence N. Kwong, Zeyad Abouelfetouh, Anaemy Danner De Armas, Lianchun Xiao, Karthikeyan Murugesan, Natalie Danziger, Dean Pavlick, Anil Korkut, Jeffrey S. Ross, Milind Javle, Comprehensive Immunogenomic Profiling of IDH1-/2-Altered Cholangiocarcinoma, JCO Precision Oncology, 03/28/2024, PMID 38547421, doi: 10.1200/PO.23.00544
Research Areas: Cholangiocarcinoma
Rosalba Minelli, Luigi Perelli, Benjamin J. Bivona, Sanjana Srinivasan, Desiree Catania, Bianca E. Amador, Frederick S. Robinson, Johnathon L. Rose, Christopher T. Terranova, Alejandro Hernandez Martinez, Charles E. Deckard, Courtney N. Le, Kuo-Shun Hsu, Michael Peoples, Aparna Subramaniam, Hannah C. Beird, Ningping Feng, Joseph R. Daniele, Christopher Vellano, Joseph Marszalek, Vinod Ravi, Alexander J. Lazar, Andrew Futreal, Timothy P. Heffernan, Giannicola Genovese, Virginia Giuliani, Development of advanced preclinical modeling for a comprehensive characterization of cardiac angiosarcoma biology, American Association for Cancer Research 2024, 03/22/2024, Abstract 1447, doi: 10.1158/1538-7445.AM2024-1447
Research Areas: Cardiac Angiosarcoma, Model Development
Christina L. Roland, Elise F. Nassif Haddad, Emily Z. Keung, Wei-Lien Wang, Alexander J. Lazar, Heather Lin, Manoj Chelvanambi, Edwin R. Parra, Khalida Wani, B. Ashleigh Guadagnolo, Andrew J. Bishop, Elizabeth M. Burton, Kelly K. Hunt, Keila E. Torres, Barry W. Feig, Christopher P. Scally, Valerae O. Lewis, Justin E. Bird, Ravin Ratan, Dejka Araujo, M. Alexandra Zarzour, Shreyaskumar Patel, Robert Benjamin, Anthony P. Conley, J. Andrew Livingston, Vinod Ravi, Hussein A. Tawbi, Patrick P. Lin, Bryan S. Moon, Robert L. Satcher, Bilal Mujtaba, Russell G. Witt, Raymond S. Traweek, Brandon Cope, Rossana Lazcano, Chia-Chin Wu, Xiao Zhou, Mohammad M. Mohammad, Randy A. Chu, Jianhua Zhang, Ashish Damania, Pranoti Sahasrabhojane, Taylor Tate, Kate Callahan, Sa Nguyen, Davis Ingram, Rohini Morey, Shadarra Crosby, Grace Mathew, Sheila Duncan, Cibelle F. Lima, Jean-Yves Blay, Wolf Herman Fridman, Kenna Shaw, Ignacio Wistuba, Andrew Futreal, Nadim Ajami, Jennifer A. Wargo & Neeta Somaiah, A randomized, non-comparative phase 2 study of neoadjuvant immune-checkpoint blockade in retroperitoneal dedifferentiated liposarcoma and extremity/truncal undifferentiated pleomorphic sarcoma, Nature Cancer, 02/13/2024, PMID: 38351182, doi: 10.1038/s43018-024-00726-z
Research Areas: Retroperitoneal Dedifferentiated Liposarcoma, Undifferentiated Pleomorphic Sarcoma
Reed Ayabe, Y David Seo, Rossana Segura, Brittany Fields, Khalida Wani, Sarah Johnson, Russell Witt, Manoj Chelvanambi, Courtney Hudgens, Sharia Hernandez, Nadim Ajami, Jennifer Water, Alexander Lazar, Daniel Halperin, Jeannelyn Estrella, Jess Maxwell, Correlation of cancer testis antigen expression with high type-I interferon signal and prognosis in small bowel neuroendocrine tumors, American Society of Clinical Oncology Gastrointestinal Cancers Symposium, 01/01/2024, Abstract 596, doi: 10.1200/JCO.2024.42.3_suppl.596
Research Areas: Small Bowel Neuroendocrine Tumors
2023
Wencai Ma, Li Zhao, Gayathri Devi, Hillary Hsu, Savitri Krishnamurthy, Larry Coffer, Angela Alexander, Megumi Kai, Xiaoping Wang, Huong Le-Petross, Miral Patel, Bisrat G. Debeb, Chandra Bartholomeusz, Jianhua Zhang, Xingzhi Song, Andy Futreal, The Rare Tumor Initiative, Naoto T. Ueno, Rachel Layman, Anthony Lucci, Jing Wang, Wendy A. Woodward, Building genomic and transcriptomic data among African American and Black patients with triple-negative inflammatory breast cancer, San Antonio Breast Cancer Symposium, 12/05/2023, Abstract PO2-09-05, doi: 10.1158/1538-7445.SABCS23-PO2-09-05
Research Areas: Inflammatory Breast Cancer
Alicia Gingrich, Hannah Beird, Randy Chu, Ray Traweek, Brandon Cope, Emily Z. Keung, Chris P. Scally, Kelly K. Hunt, Keila E. Torres, Christina L. Roland, Rare Tumor Initiative Team, Patient Mosaic Team, P. Andrew Futreal, Andrew Bishop, B. Ashleigh Guadagnolo, Devarati Mitra, Ahsan Farooqi, Dejka Araujo, M. Alejandra Zarzour, J. Andrew Livingston, Anthony Conley, Shreyaskumar Patel, Vinod Ravi, Neetah Somaiah, Alexander J. Lazar, Ravin Ratan, Elise F Nassif, Leiomyosarcoma intratumoral macrophage infiltrates are associated with different clinical and genomic presentations, Connective Tissue Oncology Society 2023, 11/01/2023, Poster P394
Research Areas: Leiomyosarcoma
Elise F. Nassif, Hannah Beird, Akash Mitra, Bin Liu, Kevin McBride, Wei-Lien Wang, Davis Ingram, Khalida Wani, Emily Z. Keung, Rare Tumor Initiative Team, Patient Mosaic Team, Alex Zarzour, Anthony Conley, Dejka Araujo, J. Andrew Livingston, Ravin Ratan, Shreyaskumar Patel, Vinod Ravi, Robert Benjamin, Alexander J. Lazar, Christina L. Roland, P. Andrew Futreal, Neeta Somaiah, Histology specific intratumoral B-cell biology in alveolar soft-part sarcomas (ASPS) in response to durvalumab-tremelimumab (D-T), Connective Tissue Oncology Society 2023, 11/01/2023, Poster P100
Research Areas: Alveolar Soft-part Sarcoma
Elise Nassif Haddad, Rossana Lazcano, R Morey, Davis Ingram, Khalida Wani, Alicia Gingrich, Michael Nakazawa, Ryan Denu, Christina Roland, Neetah Somaiah, Andrew Livingston, Alex Zarzour, Anthony Conley, Dejka Araujo, Joseph Ludwig, Shreyaskumar Patel, Robert Benjamin, Vinod Ravi, Ravin Ratan, Emily Z Keung, Alexander J Lazar, Patterns of Expression of Immune Biomarkers in Leiomyosarcomas (LMS), NCI Strategic Advances in Sarcoma Science, 09/01/2023
Research Areas: Leiomyosarcoma
Xiaoping Wang, Li Zhao, Xingzhi Song, Xiaogang Wu, Savitri Krishnamurthy, Takashi Semba, Shan Shao, Mark Knafl, Larry W. Coffer II, Angela Alexander, Anita Vines, Swetha Bopparaju, Wendy A. Woodward, Randy Chu, Jianhua Zhang, Clinton Yam, Lenora W. M. Loo, Scott Eric Woodman, Andrew Futreal, Rare Tumor Initiative Team, Debu Tripathy and Naoto T. Ueno, Genomic and transcriptomic analyses identify distinctive features of triple-negative inflammatory breast cancer, Cancer Research, 04/01/2023, Abstract 1395, doi: 10.1158/1538-7445.AM2023-1395
Research Areas: Inflammatory Breast Cancer
2022
Miles C. Andrews, Junna Oba, Chang-Jiun Wu, Haifeng Zhu, Tatiana Karpinets, Caitlin A. Creasy, Marie-Andree Forget, Xioxing Yu, Xingzhi Song, Xizeng Mao, A. Gordon Robertson, Gabriele Romano, Peng Li, Elizabeth M. Burton, Yiling Lu, Robert Szczepaniak Sloane, Khalida M. Wani, Kunal Rai, Alexander J. Lazar, Lauren E. Haydu, Matias A. Bustos, Jianjun Shen, Yuiping Chen, Margaret B. Morgan, Jennifer A. Wargo, Lawrence N. Kwong, Cara L. Haymaker, Elizabeth A. Grimm, Patrick Hwo, Dave S.B. Hoon, Jianhua Zhang, Jeffrey E. Gershenwald, Michael A. Davies, P. Andrew Futreal, Chantale Bernatchez, Scott E. Woodman, Multi-model molecular programs regulate melanoma cell state, Nature Communications, 07/09/2022, PMC9271073, doi: 10.1038/s41467-022-31510-1
Research Areas: Melanoma
Sharia Hernandez, Rossana Lazcano Alejandra Serrano, Steven Powell, Larissa Kostousov, Jay Mehta, Khaja Khan, Wei Lu, Luisa M. Solis, Challenges and Opportunities for Immunoprofiling Using a Spatial High-Plex Technology: The NanoString GeoMx® Digital Spatial Profiler, Frontiers in Oncology, 06/28/2022, PMC9277770, doi: 10.3389/fonc.2022.890410
Research Areas: Analytical Tools Development
Shiao-Pei S. Weathers, Haifeng Zhu, Mark Knafl, Ashish Damania, Carlos Kamiya-Matsuoka, Rebecca A. Harrison, Larry Lyons, Cindy Yun, Walter C. Darbonne, Monica Loghin, Marta Penas-Prado, Nazanin Majd, W. K. Alfred Yung, Barbara Jane O'Brien, Ignacio Ivan Wistuba, Andrew Futreal, Jennifer Ann Wargo, Nadim J. Ajami, Scott Eric Woodman, and John Frederick de Groot, Baseline tumor genomic and gut microbiota association with clinical outcomes in newly diagnosed glioblastoma (GBM) treated with atezolizumab in combination with temozolomide (TMZ) and radiation, American Society of Clinical Oncology 2022, 06/01/2022, Abstract 2006, doi: 10.1200/JCO.2022.40.16_suppl.2006
Research Areas: Glioblastoma, Microbiome
Daniel M. Halperin, Suyu Liu, Arvind Dasari, David Fogelman, Priya Bhosale, Armeen Mahvash, Jeannelyn S. Estrella, Laura Rubin, Ajaykumar C. Morani, Mark Knafl, Tim A. Overeem, Szu-Chin Fu, Luisa M. Solis, Edwin Parra Cuentas, Anuj Verma, Hong-Lei Chen, Swati Gite, Priya Subashchandrabose, Shannon Dervin, Katja Schulze, Walter C. Darbonne, Cindy Yun, Ignacio I. Wistuba, P. Andrew Futreal, Scott E. Woodman, James C. Yao, Assessment of Clinical Response Following Atezolizumab and Bevacizumab Treatment in Patients With Neuroendocrine Tumors: A Nonrandomized Clinical Trial, JAMA Oncology, 04/01/2022, PMC8990358, doi: 10.1001/jamaoncol.2022.0212
Research Areas: Neuroendocrine Tumors