Zhao Laboratory

Chen F, Li H, Wang Y, Tang X, Lin K, Li Q, Meng C, Shi W, Leo J, Liang X, Zhang J, Van V, Mahmud I, Wei B, Lorenzi P, Raso M, Aparicio A, Lu Y, Frigo D, Gan B, Zhao D*. CHD1 loss reprograms SREBP2-driven cholesterol synthesis to fuel androgen-responsive growth and castration resistance in SPOP-mutated prostate tumors. Nature Cancer. In press.

Meng C, Lin K, Shi W, Teng H, DeBruine A, Wang Y, Chen F, Leo J, Zhang J, Van V, Maldonado K, Gan B, Ma L, Lu Y*, Zhao D*.Histone Methyltransferase ASH1L Primes Metastases and Metabolic Reprogramming of Macrophages in the Bone Niche. Nature Communications. In press

Shi W, Wang Y, Zhao Y, Kim JJ, Li H, Meng C, Chen F, Zhang J, Mak DH, Van V, Leo J, St Croix B, Aparicio A, Zhao D*. Immune Checkpoint B7-H3 is a Therapeutic Vulnerability in Prostate Cancer Harboring PTEN and TP53 Deficiencies. Science Translational Medicine. 2023 May 10; 15(695): eadf6724. doi: 10.1126/scitranslmed.adf6724. PMID: 37163614.

Li H, Wang Y, Lin K, Venkadakrishnan V, Bakht M, Shi W, Meng C, Zhang J, Tremble K, Liang X, Song J, Feng X, Van V, Deng P, Burks J, Aparicio A, Keyomarsi K, Chen J, Lu Y, Beltran H, Zhao D*. CHD1 promotes sensitivity to Aurora kinase inhibitors by suppressing interaction of AURKA with its coactivator TPX2. Cancer Res. 2022. DOI: 10.1158/0008-5472.CAN-22-0631. PMID: 35771632

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