Lab Members

Hojong Yoon, Ph.D. 
Principal Investigator
Assistant Professor, Experimental Therapeutics
Assistant Member, James P. Allison Institute
Ph.D., Harvard University
B.S., Seoul National University
HYoon3@MDAnderson.org

Hojong Yoon is an assistant professor in the Experimental Therapeutics department at UT MD Anderson, and an assistant member of the James P. Allison Institute. He received his bachelor’s degree in pharmacy from Seoul National University (SNU) in South Korea and his Ph.D. in chemical biology from Harvard University, where he trained under Dr. Eric Fischer and Dr. Nathanael Gray. During his doctoral studies, he investigated the mechanisms of molecular glue-mediated targeted protein degradation. As a postdoctoral fellow with Dr. Benjamin Ebert at the Dana-Farber Cancer Institute and the Broad Institute, he developed approaches to systematically identify molecular glues and uncovered new mechanisms of their mode of action.

In 2025, Hojong started his independent research group at UT MD Anderson. The Yoon Lab focuses on developing innovative small-molecule therapeutics to target previously undruggable proteins and on elucidating drug mechanisms at the molecular level. By integrating chemical biology, protein biochemistry, medicinal chemistry, functional genomics and proteomics, the lab aims to discover small molecules that induce novel protein-protein interactions, thereby expanding the scope of therapeutic intervention and redefining “druggability.”