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Kappadath Laboratory
S. Cheenu Kappadath, Ph.D.
Principal Investigator
Imaging Physics
Associate Professor
We are adapting novel nuclear medicine and PET imaging technologies into advanced clinical applications.
Our research is focused on advancing imaging and diagnosis with clinical nuclear medicine (CNM), positron emission tomography (PET), single photon emission tomography (SPECT) and x-ray computed tomography (CT) by applying physics, engineering and mathematics to improve the quantitative accuracy.
We aim to improve clinical image quality through innovations in data acquisition and image generation. We adapt novel nuclear medicine technologies and incorporate advanced computational techniques to aid clinicians in their diagnosis and patient-specific radionuclide treatment planning.
Our lab is specifically working on research topics related to:
- Liver-directed Yttrium-90 microsphere therapy
- Molecular breast imaging
- Quantitative imaging with SPECT, PET & CT
- Patient-specific dosimetry
Current Grant Funding
Principal Investigator: Quantitative 99mTc-Sestamibi Molecular Breast Imaging (MBI) using GE Discovery NM750b
GE-CABI, General Electric, 9/1/2015-8/31/2017
Completed Grant Funding
Principal Investigator: A novel dose calculation method for targeted radionuclide therapy
NIH/NCI R01-CA13896-03 (Sub-award No. 601889), PI: Firas Mourtada, Ph.D., Christiana Care Health Services, 8/1/2012-7/31/2016
Co-Investigator: Multi-modal reconstruction and quantitative SPECT imaging
LS2012-00036240LG-03, Siemens Medical Solutions, PI: Homer Macapinlac, M.D., 1/15/2012-8/31/2016
Principal Investigator: Quantitative 90Y PET/CT: Quest Site Assessment Study
SIRTEX Medical Limited, 2/2/2014-2/1/2015
Principal Investigator: Develop methodology to separately compute the trabecular and cortical bone-mineral density using the GE Discovery CT 750HD scanner with GSI
GE-CABI, General Electric, 2/1/2013-3/31/2014
Principal Investigator: Optimization of the Yttrium-90 bremsstrahlung SPECT/CT for SymbiaT SPECT/CT scanners
Siemens Medical Solutions, 2/1/2012-1/31/2013