Mazumdar Laboratory
Abhijit Mazumdar, Ph.D.
Principal Investigator
- Departments, Labs and Institutes
- Labs
- Mazumdar Laboratory
Area of Research
- Breast Cancer
Members of the Mazumdar Lab use whole genome approaches at the DNA, RNA, proteomic and metabolomic levels to investigate breast biology and transformation. Through these studies, we seek to identify new strategies to treat and prevent breast cancer.
About the Mazumdar Lab (formerly the Brown Lab)
Through our research, we are focused on identifying molecules that are critical for ER-negative breast cancer development and progression by:
- Identifying critical molecular pathways involved with breast cell growth and transformation
- Investigating the functions of signaling molecules activated by these pathways
- Developing strategies targeting these signaling molecules that are capable of blocking or interfering with transformation and cell growth
- Carrying these strategies forward to clinical trials focused on the prevention or treatment of breast cancer
We use a wide range of studies to support this research, including molecular studies of gene expression, cellular biological studies of normal and premalignant human breast cells and small molecule inhibitors in transgenic and knockout mice. We currently have projects supported by Department of Defense (DoD) grants, a Breast Cancer Research Foundation (BCRF) grant and a National Cancer Institute (NCI) PREVENT grant to conduct studies to identify new targets for the treatment and prevention of breast cancer.
Our Research
Learn more about the Mazumdar Lab research projects
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Research Areas
Find out about the four types of research taking place at UT MD Anderson.