Swathi Arur, Ph.D.
Areas of Research
- Developmental Biology Research
- miRNAs Research
- ncRNAs Research
- Nutrition Research
- Cancer Metastasis Research
Welcome to the Arur Laboratory. We use multidisciplinary approaches and model systems with the goal to gain knowledge and understanding on principles that regulate female fertility. We focus on meiosis I, which is largely completed in the female fetus in vertebrates. Specifically, we focus on the role of maternal environment and nutrition on progression of female meiosis I, and its impact on birth and development of the progeny.
- Female germ cell development
- Nutritional and environmental signals that coordinate female fertility
- Mechanisms of cancer progression and metastasis
Research projects in the Arur Laboratory are focused on two major areas:
- Unraveling the environmentally regulated mechanisms and molecules that control meiotic I progression in female germ cells. We use C. elegans as our model system for this work.
- Identifying principles and players that regulate tumor progression upon metabolic signaling rather than through the increase in mutational burden. We use mouse and cultured cells as models for this work. These efforts should allow us to identify metabolic checkpoints impeding tumor growth.
Explore the various links on our web page and get to know us and our research.We welcome discussions; please contact us using our email address.
Meet the Team
From left to right: Swathi Arur, Amanda Minogue, Raisa Reyes Castro, Jacob Ortega, Kenneth Trimmer, Jacob Seeman, Deba Das, Charlotte Lee, Shin-Yu Chen, Lisa Watson, Han Bit Baek, Tokiko Furuta