AACR: Novel approach prevents cancer progression, spares surgery for majority of patients with precancerous oral lesions
Precancerous oral lesions can progress to oral cancer and are typically ablated or surgically removed as a preventive measure
Direct injection of nivolumab immunotherapy into lesions reduced toxicities and reduced lesion size by an average of 60%, decreasing the risk of cancer progression
More than 80% of treated lesions were cancer-free after one year, and patients reported improved quality of life and tolerable side effects
Direct injection...
AACR: New platform uses machine learning to predict responses in patients with lung cancer
Path-IO is a machine learning platform that incorporates pathology data to predict how patients with non-small cell lung cancer will respond...
AACR: Zedoresertib and lunresertib combination shows promising antitumor activity
Phase I trial provides early clinical proof-of-concept supporting the combination of zedoresertib and lunresertib in certain advanced solid...
AACR: Clinical trial presentations feature advances across cancer care
Early results for first-in-human and first-in-class therapies including an integrin inhibitor and a genetically engineered tumor infiltrating lymphocyte therapy
ctDNA monitoring may be changing treatment options for patients
Next-generation targeted therapies may allow de-escalation of treatment
Researchers from The University of Texas MD Anderson Cancer Center will present initial data from six clinical trials during minisymposia...
First-line targeted therapy shows antitumor activity in patients with advanced lung cancer
First-line zongertinib showed antitumor activity in treatment-naïve patients with advanced or metastatic HER2-mutant ...
AACR: UT MD Anderson shares latest breakthroughs in cancer research
ABSTRACTS: NG05, 1296, 1297, 1361, 1366, 2709, 3451, 4010, 4020, 4033, 4053, 6724, 6743, 6761, 6788, 6803
Researchers from The...
Researchers find new target to sensitize pancreatic tumors to immunotherapy
DPY30 acts as an epigenetic regulator to help pancreatic tumors maintain genomic stability
Targeting DPY30 triggers immune cell infiltration...
Study identifies strategy to overcome radiation therapy resistance in lung cancer
These results show how mitochondrial enzyme dihydroorotate dehydrogenase contributes to radiation therapy resistance
Researchers were able to...
Researchers identify blood-based biomarker for cancer risk in people with Lynch Syndrome
Lynch Syndrome (LS) is a hereditary condition involving mutations in DNA mismatch repair genes
Researchers sequenced T cell receptors in blood...
Radiation therapy improves outcomes for 'supermassive’ bile duct tumors
Patient outcomes were significantly better when treated with radiation therapy plus standard-of-care chemotherapy
First-in-class radio-theranostic utilizes novel antibody developed at UT MD Anderson
Study details the development of a novel antibody that targets a specific type of B7-H3, a protein overexpressed in many cancers