Our Treatment Approach
Treatment for testicular cancer at MD Anderson focuses on the most modern techniques in surgery, chemotherapy and other therapies. We customize your treatment to include the most advanced procedures with the least impact on your body.
Our renowned team of experts considers all the options, and then choose the best course of action specifically for you. Your personalized testicular cancer treatment may include:
- Surgery by a dedicated team of urologists, vascular surgeons, and anesthesiologists with expertise in this complex cancer
- Special nerve-sparing surgical procedures to retain as much function as possible
- The most modern restoration and prosthetic techniques
- Dose-dense chemotherapy, which allows a higher level of drugs to be given and may help prevent stem cell transplant in some patients
- Stem cell transplants at one of the premier programs in the country
Because MD Anderson is one of the nation’s largest cancer centers, we see a much greater number of patients with testicular cancer than do most oncologists. This is particularly important in surgery for testicular cancer, which is delicate, challenging and requires a great deal of expertise.
Studies have shown that the effectiveness of surgical treatment for testicular cancer depends a great deal on the number of procedures the surgeon has performed. MD Anderson’s skilled surgeons are among the most experienced in the country. This translates to optimal chances for your successful recovery.
And because we are a major cancer research center, we are able to offer clinical trials of new treatments for some types of testicular cancer.
Our Testicular Cancer Treatments
If you are diagnosed with testicular cancer, your doctor will discuss the best options to treat it. This depends on several factors, including the type and stage of the cancer and your general health.
One or more of the following therapies may be recommended to treat the cancer or help relieve symptoms.
Orchiectomy: Surgery to remove the testicle. In most cases, orchiectomy is performed during testicular cancer diagnosis. The testicle is removed through an incision in the groin, and tissue samples are examined to determine the stage of the testicular cancer.
Retroperitoneal lymph node dissection (RPLND): For some patients, especially those with nonseminoma testicular cancer, surgery may also involve removal of lymph nodes in the abdominal area. This is done at the same time as the orchiectomy or in a second surgical procedure.
Nerve-sparing techniques: To preserve normal ejaculation, the surgeons at MD Anderson are skilled in surgical techniques that may avoid damage to the nerves surrounding retroperitoneal lymph nodes in some men.
Reconstructive surgery: Men who are uncomfortable with their appearance after orchiectomy can have a prosthesis implanted in the scrotum that provides the look and feel of a real testicle.
Possible side effects of testicular cancer surgery
If one testicle is removed to treat testicular cancer, most men can get erections and have sex if they are getting enough testosterone. If both testicles are removed, a man cannot father a child or make enough testosterone to have sex. In this case, testosterone needs to be taken in the form of a gel, patch or shot.
Because both surgical procedures may affect fertility, you may want to talk to your doctor about sperm banking if you want to start a family at some point. Sperm cells can be collected before cancer treatment and frozen for future use.
Seminomas, which are the form of testicular cancer found most often, are very sensitive to radiation treatment. In fact, the treatment dosage is only about one-third of that required for prostate cancer, and the treatment cycle is only two weeks.
Radiation is performed after surgery to remove the testicle (orchiectomy). If the tumor was a seminoma, the oncologist may choose "watchful waiting" to see if the testicular cancer returns or use radiation to treat the lymph nodes along the spine, where the majority of recurrences are located.
Even if testicular cancer comes back, it is still treatable with radiation or chemotherapy. Radiation treatment has an average recurrence rate of about 5%. Radiation also can be used after chemotherapy if any cancer remains.
Other types of testicular cancer (nonseminoma) are more resistant to radiation. They are treated with orchiectomy, chemotherapy, and surgery to remove affected lymph nodes.
Chemotherapy is sometimes used in conjunction with surgical removal of the testicle to make sure all the cancer cells have been destroyed. For men with advanced tumors that have spread beyond the testicle or metastasized (spread) to distant areas of the body, chemotherapy is usually given for nine weeks or longer.
The most frequently used chemotherapy combinations for testicular cancer are:
- BEP: Blenoxane® (bleomycin), Etopophos® or Vepesid® (etoposide), and Platinol® (cisplatin)
- EP: Etopophos® or Vepesid® (etoposide) and Platinol® (cisplatin)
For men with poor-risk testicular cancer, MD Anderson uses an approach called dose-dense chemotherapy. A higher number of chemotherapy drugs are given at more-frequent intervals; this allows the cancer cells less time to recover between each treatment.
Stem Cell Transplantation
A stem cell transplant is used most often for testicular cancers that have returned after successful treatment. MD Anderson has one of the most-advanced stem cell transplant centers in the nation.
Our Testicular Cancer Clinical Trials
Since MD Anderson is one of the nation’s leading research centers, we’re able to offer a number of clinical trials (research studies) of new treatments for testicular cancer.
Treatment at MD Anderson
Testicular cancer is treated in our Genitourinary Center.
MD Anderson patients have access to clinical trials offering
promising new treatments that cannot be found anywhere else.
Find the latest news and information about testicular cancer in our
Knowledge Center, including blog posts, articles, videos, news
releases and more.
I have always been an athletic guy. I played football in high school
and college. But after my testicular cancer treatment, I was
overweight, and I wasn't leading a healthy lifestyle. I knew I needed
to get stronger to prevent my cancer from coming back.
CrossFit turned out to be exactly what I needed. It helped me do a lot more than just get back in shape. It helped me find my confidence and connect with others.
Starting CrossFit after testicular cancer treatment
My testicular cancer treatment included three cycles of chemotherapy and a surgery. It was tough, but following the surgery, I was declared cancer-free.
Two years later, I learned a CrossFit gym would be opening in my hometown. I was so excited.
I missed the competitiveness and locker room feel I had known playing football in high school and college. This was going to be how I would become healthy again. The first day I went, I knew I was hooked. My gym is like a big diverse family. We would do anything for each other, inside the gym or out.
I know that if I don't take care of my body, it will not take care of me. I have cancer scar tissue in my body, and I need to do everything in my power to strengthen it and build it up so the cancer won't come back.
CrossFit was difficult initially, but I've come a long way since
then. I remember my first day. I couldn't do a full range of motion
sit-up. But that's all in the past now. Since starting CrossFit I've
lost 84 lbs., and I've become a CrossFit level one trainer.
Inspiring others through CrossFit
Am I an elite athlete? No, and I probably never will be. But I have fun, and I am in the best shape of my life. After cancer, I knew my life had to change. So, I stepped outside of my comfort zone and made one of the best decisions in my life.
Many of my friends from CrossFit didn't know about my cancer journey, but that changed when my gym posted my story on their Facebook page. The outpouring of support I received was amazing. My story provided many with motivation, although that wasn't my intention. I wasn't just a big guy going to the gym to get in shape. I was working out to increase my chances of living a cancer-free life. It's really made both myself and others consider why and how we do things.
Before cancer, I, like many other people, just went to the gym because I thought I had to. I wanted to look strong, but I had no other motivation. Now, when I go to the gym, I am going to make my body stronger than anything that could try to take me down again. I look forward to going every single day because I have been blessed with the ability and knowledge to live every day to the fullest.