The Lung Cancer SPORE was originally given jointly to MD Anderson and The University of Texas Southwestern Medical Center in Dallas in 1996. Both institutions have received $6.5 million in SPORE renewed funding.
The collaboration has produced several key findings including the identification of three lung cancer tumor suppressor genes on chromosome 3 that dramatically reduced human lung cancer growth in mice.
Lung cancer was diagnosed in an estimated 215,020 Americans in 2008, and 161,840 died from the disease, according to the American Cancer Society.
John D. Minna, M.D., of The University of Texas Southwestern Medical School and MD Anderson's Jack Roth, M.D., professor and Bud Johnson Clinical Distinguished Chair, serves as the lung cancer SPORE's multi-principal investigators.