Tao Wang Laboratory
Tao Wang, Ph.D.
Principal Investigator
- Departments, Labs and Institutes
- Labs
- Tao Wang Laboratory
Areas of Research
- Artificial Intelligence
- Bioinformatics
- Cancer Genomics
- Computational Biology
- Genomics
- Immunity
- Immunology
- Immunotherapy
- Next Generation Sequencing
- Single-Cell Genomics
- Structural Biology
- Tumor Heterogeneity
- Tumor Microenvironment
The Tao Wang Lab is a top artificial intelligence (AI)-for-science lab at UT MD Anderson, specializing in the development and deployment of AI-driven solutions for immunology discovery. Our interdisciplinary research integrates machine learning, statistics, medicine and biology to extract meaningful insights from high-dimensional biomedical data. Our work focuses on leveraging public and in-house high-throughput datasets to uncover mechanistic insights into human diseases, particularly immunological disorders, with implications for diagnosis, prognosis and treatment. We apply cutting-edge AI techniques to model T/B cell antigens and receptor sequences at the molecular level, analyze single cell and spatially resolved transcriptomics data at the cellular level and integrate genomics with electronic medical records at the patient level. By pioneering AI methodologies for multi-scale immunological data, our ultimate goal is to transform patient care through improved disease prediction, treatment personalization and therapeutics discovery.
Recent Publications
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Interpretable AI Model Reveals Spatial Codes of Cell Recruitment in Tissues
Nature Biomedical Engineering, 2026
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Profiling Antigen Binding Affinity of B Cell Repertoires in Tumors by Deep Learning
Nature Cancer Opens a new window
2025
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Mapping Cellular Interactions from Spatially Resolved Transcriptomics Data
Nature Methods Opens a new window
2024
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Interpreting the B Cell Receptor Repertoire With Single-Cell Gene Expression Using Benisse
Nature Machine Intelligence Opens a new window
2022
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Deep Learning-Based Prediction of T Cell Receptor-Antigen Binding Specificity
Nature Machine Intelligence Opens a new window
2021
Tao Wang Lab Publications
See a full publications list
Lab News
Oct 2026
Yi Han joins the School of Computer Science of Oklahoma University as an assistant professor
August 2026
Welcome Jiayi Li and Parth Baware to the lab
July 2026
Jia Yao's SPACER paper is accepted at Nature Biomedical Engineering
June 2026
Welcome Harrison Cohen, a University of North Carolina undergraduate student, to join the Tao Wang Lab for the summer
Welcome Woojung Flora Yi, a CURE/UPWARDS summer trainee, who is joining the Tao Wang Lab for the summer
April 2026
Yi and Yuqiu's manuscript on pMTnet-v2 was accepted for publication at Nature Communications
March 2026
Yinglu's commentary was accepted for publication at Science Immunology
February 2026
Bing Song joins Indiana University School of Medicine as an assistant professor
February 2026
Yue Xuan joins the Tao Wang Lab as a Ph.D. student from the UT MD Anderson UTHealth Houston Graduate School of Biomedical Sciences
November 2025
Tao Wang is awarded the Cancer Bioengineering Collaborative FY26 Seed Program Grant, together with Cassian Yee and Caleb Bashor (Rice University)
Tao Wang Lab Members
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Research Areas
Find out about the four types of research taking place at UT MD Anderson.