Tao Wang Laboratory
Tao Wang, Ph.D.
Principal Investigator
- Departments, Labs and Institutes
- Labs
- Tao Wang Laboratory
Areas of Research
- Artificial Intelligence
- Bioinformatics
- Cancer Genomics
- Computational Biology
- Genomics
- Immunity
- Immunology
- Immunotherapy
- Next Generation Sequencing
- Single-Cell Genomics
- Structural Biology
- Tumor Heterogeneity
- Tumor Microenvironment
The Tao Wang Lab is a top artificial intelligence (AI)-for-science lab at MD Anderson, specializing in the development and deployment of AI-driven solutions for immunology discovery. Our interdisciplinary research integrates machine learning, statistics, medicine and biology to extract meaningful insights from high-dimensional biomedical data. Our work focuses on leveraging public and in-house high-throughput datasets to uncover mechanistic insights into human diseases, particularly immunological disorders, with implications for diagnosis, prognosis and treatment. We apply cutting-edge AI techniques to model T/B cell antigens and receptor sequences at the molecular level, analyze single cell and spatially resolved transcriptomics data at the cellular level and integrate genomics with electronic medical records at the patient level. By pioneering AI methodologies for multi-scale immunological data, our ultimate goal is to transform patient care through improved disease prediction, treatment personalization and therapeutics discovery.
Recent Publications
Profiling Antigen Binding Affinity of B Cell Repertoires in Tumors by Deep Learning
Nature Cancer, 2025
Mapping Cellular Interactions from Spatially Resolved Transcriptomics Data
Nature Methods, 2024
Netie: inferring the evolution of neoantigen–T cell interactions in tumors
Nature Methods, 2022
Interpreting the B-cell receptor repertoire with single-cell gene expression using Benisse
Nature Machine Intelligence, 2022
Deep learning-based prediction of the T cell receptor-antigen binding specificity
Nature Machine Intelligence, 2021
Tao Wang Lab Publications
Lab News
November 2025
Dr. Tao Wang is awarded the Cancer Bioengineering Collaborative FY26 Seed Program Grant, together with Dr. Cassian Yee and Dr. Caleb Bashor (Rice University)!
July 2025
We warmly welcome Yinglu Tang, joining the Tao Wang Lab as a postdoc!
July 2025
We warmly welcome Zixu Wang, joining the Tao Wang Lab as a postdoc!
May 2025
We moved to MD Anderson!
March 2025
Bing Song and Kevin Wang’s antibody-antigen interaction prediction paper is accepted by Nature Cancer!
March 2025
Dr. Tao Wang is awarded a Department of Defense (DoD) Breast Cancer Research Program (BCRP) grant as partnering Principal Investigator (PI), together with Dr. Prasanna Alluri at UT Southwestern Medical Center as the lead PI.
February 2025
Dr. Tao Wang is awarded an R01 grant from the National Institute of Allergy and Infectious Diseases (NIAID).