Perelli Laboratory
Luigi Perelli, M.D., Ph.D.
Principal Investigator
Areas of Research
- Cancer Biology
- Cancer Genomics
- Cancer Metabolism
- Cancer Metastasis
- Chromatin Remodelers
- Epigenetics
- Evolution and Development
- Genome Evolution
- Glioblastoma
- Kidney Cancer
- Pancreatic Cancer
Welcome to the Perelli Laboratory. We are passionate cancer biologists focused on understanding how and why normal cells transform into cancer cells. The Perelli Lab applies principles of evolutionary biology, considering each tumor as an ecosystem where different "species" (cancer cells) fight for survival in a complex environment. We investigate how "selection of the fittest" drives cancer progression and resistance to therapies.
Meet Dr. Perelli
Luigi Perelli, M.D., Ph.D., is an assistant professor of Cancer Biology, a CPRIT Scholar in cancer research and a certified Italian medical doctor with a Ph.D. in the oncological sciences.
Dr. Perelli’s research program focuses on shedding light on key unsolved topics in cancer biology, including the malignant transformation of ‘normal’ cells and the role of interplay between genotype-phenotype in shaping cancer evolution. His expertise bridges clinical practice and a foundational knowledge of genetics and genomics, and his team leverages cutting edge technologies, including new tools for generating animal models of cancer and genome-tagging technologies coupled with multi-omic technologies.
To date, his discoveries have been published in top-tier scientific journals like Nature, Nature Cancer and Cancer Cell.
- Md Imtiaz Khalil, Ph.D.
- Aastha Pandey, Ph.D.
- Haoyu Tang, Ph.D.
- National Institutes of Health
- Department of Defense
- Cancer Prevention and Research Institute of Texas (CPRIT)
- MD Anderson
Contact Us
Principal Investigator
Luigi Perelli, M.D., Ph.D.
Assistant Professor, Cancer Biology
LPerelli@MDAnderson.org
Mailing Address
MD Anderson Cancer Center
Cancer Biology
1515 Holcombe Blvd.
Unit 1906
Houston, TX 77030-4009