Selected Pan Lab Publications

Kim YS, Gillespie SM, Geraghty AC, Yalçın B, Ivec AE, Yang A, Mancusi R, Hysinger J, Reed J, Drexler R, Quezada M, Malacon K, Woo P, Byun YG, Mount C, Lam M, Pan Y, Zuchero JB, Trotter J, Monje M.

Neuroligin-3-CSPG4 interaction maintains oligodendrocyte precursor cell progenitor state and promotes glioma proliferation through mechanotransduction. Opens a new window

Nat Neurosci 2026. Online ahead of print.

Aghoghovwia BE, Ban K, Stavropoulos D, Chen CY, Wei B, Hamblett AS, Sharafaldin S, El-Toukhy H, Harris M, Hok C, Chandramouli VK, Cerda CMM, Bertrand RE, Alnassiry S, Lorenzi PL, Gutmann DH, Chang KC, Mahalingam R, Pan Y.

Carboplatin induces optic nerve oligodendrocyte loss and impairs myelin sheath microstructure in a mouse model of neurofibromatosis type 1 (NF1). Opens a new window

Neuro Oncol 2026. Online ahead of print.

Kasm KAA, Dembla S, Hirbe AC, Shepherd AJ, Pan Y.

Culturing primary adult mouse dorsal root ganglion neurons for assessing neuronal function following treatment with tumor cell-conditioned medium Opens a new window

J Vis Exp (232), 2026.

Aghoghovwia BE, Shen CE, Bano S, Shyamala N, Echeandia Marrero A, Irshad K, Sharafaldin S, Brossier NM, Pan Y.

Current states in understanding oligodendroglia-mediated neurological issues in neurofibromatosis type 1 (NF1). Opens a new window

Acta Neuropathol Commun 13(1):202, 2025.

Acharya TK, Pan Y, Grace PM, Heijnen CJ, Mahalingam R.

Deciphering transcriptomic changes in chemobrain: a comprehensive review. Opens a new window

Acta Neuropathol Commun 13(1):186, 2025.

Singh AK, Pan Y.

Neuronal transfer of mitochondria to tumour cells promotes cancer spread. Opens a new window

Nature 644(8075):46-47, 2025.

Shen CE, Echeandía Marrero AS, Pan Y.

Disrupting neuron-tumor networking connections. Opens a new window

Cell Chem Biol 32(3):386-388, 2025.

Huang YK, Wang TM, Chen CY, Li CY, Wang SC, Irshad K, Pan Y, Chang KC.

The role of ALDH1A1 in glioblastoma proliferation and invasion. Opens a new window

Chem Biol Interact 402:111202, 2024

Pan Y, Hysinger JD, Yalçın B, Lennon JJ, Byun YG, Raghavan P, Schindler NF, Anastasaki C, Chatterjee J, Ni L, Xu H, Malacon K, Jahan SM, Ivec AE, Aghoghovwia BE, Mount CW, Nagaraja S, Scheaffer S, Attardi LD, Gutmann DH, Monje M.

Nf1 mutation disrupts activity-dependent oligodendroglial plasticity and motor learning in mice. Opens a new window

Nat Neurosci 27(8):1555-1564, 2024.

Pan Y, Hu J.

Hormonal basis of brain fog in cancer treatment. Opens a new window

J Exp Med 221(5):e20231942, 2024.

Amit M, Anastasaki C, Dantzer R, Demir IE, Deneen B, Dixon KO, Egeblad M, Gibson EM, Hervey-Jumper SL, Hondermarck H, Magnon C, Monje M, Na'ara S, Pan Y, Repasky EA, Scheff NN, Sloan EK, Talbot S, Tracey KJ, Trotman LC, Valiente M, Van Aelst L, Venkataramani V, Venkatesh HS, Vermeer PD, Winkler F, Wong RJ, Gutmann DH, Borniger JC.

Next directions in the neuroscience of cancers arising outside the CNS. Opens a new window

Cancer Discov 14(4):669-673, 2024.

Irshad K, Brossier N, Pan Y.

Neuronal activity in brain tumor pathogenesis: adding to the complexities of central nervous system neoplasia. Opens a new window

In: Amit M, Scheff NN (eds). Cancer Neuroscience. Springer, Cham; pp. 3-25, 2023.

Irshad K, Huang YK, Rodriguez P, Lo J, Aghoghovwia BE, Pan Y, Chang KC.

The neuroimmune regulation and potential therapeutic strategies of optic pathway glioma. Opens a new window

Brain Sci 13(10):1424, 2023.

Pan Y, Monje M.

Neuron-glial interactions in health and brain cancer. Opens a new window

Adv Biol (Weinh) 6(9):e2200122, 2022.

Pan Y, Hysinger JD, Barron T, Schindler NF, Cobb O, Guo X, Yalçın B, Anastasaki C, Mulinyawe SB, Ponnuswami A, Scheaffer S, Ma Y, Chang KC, Xia X, Toonen JA, Lennon JJ, Gibson EM, Huguenard JR, Liau LM, Goldberg JL, Monje M, Gutmann DH.

NF1 mutation drives neuronal activity-dependent initiation of optic glioma. Opens a new window

Nature 594(7862):277-282, 2021.

Guo X, Pan Y, Xiong M, Sanapala S, Anastasaki C, Cobb O, Dahiya S, Gutmann DH.

Midkine activation of CD8+ T cells establishes a neuron-immune-cancer axis responsible for low-grade glioma growth. Opens a new window

Nat Commun 11(1):2177, 2020.

Pan Y, Monje M.

Activity shapes neural circuit form and function: a historical perspective. Opens a new window

J Neurosci 40(5):944-954, 2020.