Lab Members

Yuan Pan, Ph.D.
Principal Investigator

Yuan received her Ph.D. degree from the University of Iowa and her thesis work focused on understanding ion channel trafficking in photoreceptors. As a postdoctoral fellow, her research focused on microenvironmental regulation of optic pathway gliomas. Leveraging genetically engineered mouse models and neuromodulatory approaches, the Pan Laboratory is currently working on understanding neuron-glia and neuron-cancer interactions, with a focus on cancer predisposition syndromes such as neurofibromatosis type 1 (NF1).

Benjamin Emoefe Aghoghovwia, Ph.D.
Research Scientist

Benjamin obtained his doctoral degree from the University of Otago, Dunedin New Zealand, in 2018. His Ph.D. thesis and postdoctoral research mainly explored the therapeutic efficacy of stem cells on neurological disorders of the basal ganglia such as neonatal stroke and cerebral palsy using stereology as a measuring tool. His interest in expanding knowledge in Neuroscience led him to the Pan laboratory, and his current project which investigates the interaction between neuron and glial cells and determine how the interaction contributes to cognition. His career vision is to understand the mechanisms of neuron-glial interaction in neurogenetic disorders such as neurofibromatosis type 1 (NF1), which will contribute to the development of novel therapeutics, extend the frontiers of knowledge, and promote patient care.

Sama Alnassiry
Research Assistant

Sama is originally from Baghdad, Iraq, and lived most of her life in Upstate NY. Sama decided to move to Texas to join Dr. Pan’s team after obtaining her B.S. of Biomedical Sciences from Rochester Institute of Technology in 2021, where her research was primarily surrounding the bacteria Streptococcus Mutane K. Outside of the lab, Sama enjoys learning programming languages, spending time with her cat and a crisp NY fall day.

Khalil Ali Ahmad Kasm, Ph.D.
Postdoctoral Researcher

Khalil obtained his Ph.D. in pharmacology from Shanghai Jiao Tong University in 2021. His research focuses on the field of cancer neuroscience and neuropharmacology. He has eight years of research experience in chronic pain, neuronal-glial interaction and oxidative stress, and published several peer-reviewed manuscripts. His career goals are to discover the mechanism of action of novel therapies and disease-related pathogenesis using preclinical and translational research that can substantially benefit the clinical research requirements and improve the patient’s quality of life. In his free time, he enjoys swimming, football, hiking and cooking.

Tasneem Islam
Undergraduate Research Volunteer

Tasneem is a senior biochemistry major studying at the University of Houston. She has done previous research with the UH Pharmacy department in determining COVID-19 therapeutics. Tasneem hopes to attend medical school in the future and specialize in oncology. Her hobbies include involvement with her university’s choral program.
 

Khushboo Irshad, Ph.D.
Research Scientist

Khushboo completed her Ph.D. in Biochemistry at All India Institute of Medical Sciences (AIIMS), New Delhi, India, in 2013. Her Ph.D. thesis and postdoctoral research involved the study of signaling pathways implicated in brain tumors and patient-derived primary cultures. Her current interest includes the study of the intricacies between cancer cells and cells of the nervous system. Her long-term academic goal is to learn the advanced modalities that can help to better investigate the molecular mechanisms that pose challenges in the therapy of cancer patients.

Anand Singh, Ph.D.
Sr. Research Scientist

Anand is a neuroscientist with over 15 years of experience in pre-clinical drug testing and regulatory affairs. Currently, as Sr. Research Scientist at MD Anderson, Anand is handling multiple projects on chemotherapy drug treatment and assessment of neurotoxic side effects, reverse translation study of small molecule inhibitor to target oxidative phosphorylation as an anticancer strategy. Having a background in biotechnology, Anand was interested in neuroscience and completed Ph.D. in a rodent model of dopaminergic neurodegeneration. During his Ph.D. at CSIR-Indian Institute of Toxicology Research (2007-12), India, he and his colleagues established a new pesticide-induced mouse model of Parkinson’s disease. Then he moved to Linkoping University, Sweden (2012-16) for a postdoc, where he worked on the neurocircuitry of the affective dimension of inflammatory pain and identified EP3 receptor of prostaglandin present in the serotonergic neurons drives inflammatory pain-induced aversion. Anand came to Houston in early 2017 and started his 2nd postdoc in the Department of Neuroscience at Baylor College of Medicine. During his almost 2 years at Baylor, he worked on the EC-DG neurocircuitry in the transgenic mouse model of Mild Cognitive Impairment. In the winter of 2018, Anand joined the Neuroimmunology Lab as a Research Scientist in the Symptom Research at MD Anderson and since then he has been working on chemotherapy-induced cognitive impairments (chemobrain).