Publications

2019

Zhao J, Wen X, Tian L, Li T, Xu C, Wen X, Melancon MP, Gupta S, Shen B, Peng W, Li C. Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer. Nature Communications 10(899):1-14, 2019. e-Pub 2/2019.

2018

Tian L, Qiao Y, Lee P, Wang L, Chang A, Ravi S, Lu L, Singhana B, Zhao J, Melancon MP. Antitumor efficacy of liposome-encapsulated NVP-BEZ 235 in combination with irreversible electroporation. Drug Delivery 25(1):668-678, 2018. e-Pub 2/2018. PMCID: PMCPMC6058606.

Tian L, Lu L, Feng J, Melancon MP. Radiopaque nano and polymeric materials for atherosclerosis imaging, embolisation and other catheterization procedures. Acta Pharmaceutica Sinica B 8(3):360-370, 5/2018. PMCID: PMCPMC5990339.

Qiao Y, Gumin G, Maclellan C, Wallace M, Bouchard R, Lang F, Stafford RJ, Melancon MP. Magnetic resonance and photoacoustic imaging for treatment planning of brain tumor mediated by mesenchymal stem cell-labeled with multifunctional nanoparticle. Nanotechnology 29(16):165101, 4/2018. e-Pub 2/2018. PMCID: PMCPMC5863233.

Tian L, Lee P, Singhana B, Chen A, Qiao Y, Lu L, Martinez J, Tasciotti E, Jacobsen MC, Melancon A, McArthur M, Eggers M, Huang S, Melancon MP. In vivo imaging of radiopaque resorbable inferior vena cava filter infused with gold nanoparticles. Progress in Biomedical Optics and Imaging - Proceedings of SPIE 10576(105762S), 2/2018. e-Pub 2/2018.

Cao Q, Yan X, Chen K, Huang Q, Melancon MP, Lopez G, Cheng Z, Li C. Macrophages as a Potential Tumor-Microenvironment Target for Noninvasive Imaging of Early Response to Anticancer Therapy. Biomaterials 152:63-76, 1/2018. e-Pub 10/2017. PMCID: PMC5693615.

2017

Melancon MP, Appleton Figueira T, Fuentes DT, Tian L, Qiao Y, Gu J, Gagea M, Ensor JE, Muñoz NM, Maldonado KL, Dixon K, McWatters A, Mitchell J, McArthur M, Gupta S, Tam AL. Development of an Electroporation and Nanoparticle-based Therapeutic Platform for Bone Metastases. Radiology 286(1):161721, 1/2018. e-Pub 8/2017. PMID: 28825892.

Huang SY, Eggers M, McArthur MJ, Dixon KA, McWatters A, Dria S, Hill LR, Melancon MP, Steele JR, Wallace MJ. Safety and Efficacy of an Absorbable Filter in the Inferior Vena Cava to Prevent Pulmonary Embolism in Swine. Radiology 285(3):161880, 12/2017. e-Pub 7/2017. PMCID: PMC5708283.

Tian L, Lee P, Singhana B, Chen A, Qiao Y, Lu L, Martinez JO, Tasciotti E, Melancon A, Huang S, Eggers M, Melancon MP. Radiopaque Resorbable Inferior Vena Cava Filter Infused with Gold Nanoparticles. Sci Rep 7(1):2147, 5/2017. e-Pub 5/2017. PMCID: PMC5438341.

Tian L, Chang A, Melancon MP. Exploring gold nanoparticle interactions with proteins and the tumor microenvironment in biological systems. Transl Cancer Res 6(Suppl 2):S309-S312, 3/2017. e-Pub 3/2017. PMCID: PMC5497297.

2016

Tian L, Lu L, Qiao Y, Ravi S, Salatan F, Melancon MP. Stimuli-responsive gold nanoparticles for cancer diagnosis and therapy. J Funct Biomater 7(3), 2016. e-Pub 7/2016. PMID: 27455336.

Zhou M, Melancon MP, Stafford RJ, Li J, Nick AM, Tian M, Sood AK, Li C. Precision Nanomedicine Using Dual Positron Emission Tomography and Magnetic Resonance Temperature Imaging-Guided Photothermal Therapy. J Nucl Med 57(11):1778-1783, 11/2016. e-Pub 6/2016. PMCID: PMC5093070.

Hosoya H, Dobroff AS, Driessen WH, Cristini V, Brinker LM, Staquicini FI, Cardó-Vila M, D'Angelo S, Ferrara F, Proneth B, Lin YS, Dunphy DR, Dogra P, Melancon MP, Stafford RJ, Miyazono K, Gelovani JG, Kataoka K, Brinker CJ, Sidman RL, Arap W, Pasqualini R. Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release. Proc Natl Acad Sci U S A 113(7):1877-82, 2/2016. e-Pub 2/2016. PMCID: PMC4763738.

Tam AL, Melancon MP, Abdelsalam M, Figueira TA, Dixon K, McWatters A, Zhou M, Huang Q, Mawlawi O, Dunner K, Li C, Gupta S. Imaging Intratumoral Nanoparticle Uptake after Combining Nanoembolization with Various Ablative Therapies in Hepatic VX2 Rabbit Tumors. J Biomed Nanotechnol 12(2):296-307, 2/2016. PMCID: PMC5069970.

2015

Zhao J, Lee P, Wallace MJ, Melancon MP. Gold Nanoparticles in Cancer Therapy: Efficacy, Biodistribution, and Toxicity. Curr Pharm Des 21(29):4240-51, 10/2015. e-Pub 8/2015. PMID: 26323426.

Zhao J, Qiao J, Zhou M, Gupta S, Li C, Melancon MP. Anti-tumor Efficacy Study using Irreversible Electroporation and Doxorubicin-loaded Polymeric Micelles. ACS Macro Lett 4(10):1081-1084, 10/2015. e-Pub 9/2015. PMCID: PMC5435371.

Mitcham T, Dextraze K, Taghavi H, Melancon M, Bouchard R. Photoacoustic imaging driven by an interstitial irradiation source. Photoacoustics 3(2):45-54, 6/2015. e-Pub 3/2015. PMCID: PMC4519807.

Zhao J, Melancon MP, Zhou M. Nanoparticle  Formulation  to  Improve  the  Efficacy  of  Radiation  Therapy Against Radiation-Resistant Leukemia. EBioMedicine 2(6):486, 6/2015. e-Pub 5/2015. PMCID: PMC4535157.

Singhana B, Chen A, Slattery P, Yazdi IK, Qiao Y, Tasciotti E, Wallace M, Huang S, Eggers M, Melancon MP. Infusion of Iodine-Based Contrast Agents into Poly(p-dioxanone) as a Radiopaque Resorbable IVC Filter. J Mater Sci Mater Med 26(3):124, 3/2015. e-Pub 2/2015. PMID: 25690619.

2014

Zhou M, Singhana B, Liu Y, Huang Q, Mitcham T, Wallace MJ, Stafford RJ, Bouchard RR, Melancon MP. Photoacoustic- and Magnetic Resonance-Guided Photothermal Therapy and Tumor Vasculature Visualization Using Theranostic Magnetic Gold Nanoshells. J Biomed Nanotechnol 11(8):1385-1400, 2014. PMID: 26295144.

Tam AL, Melancon MP, Ensor J, Liu Y, Dixon K, McWatters A, Gupta S. Rabbit Hepatic Arterial Anatomy Variations:  Implications on Experimental Design. Acta Radiol 55(10):1226-33, 12/2014. e-Pub 11/2013. PMCID: PMC4262404.

Zhao J, Vykoukal J, Abdelsalam M, Recio-Boiles A, Huang Q, Qiao Y, Singhana B, Wallace M, Avritscher R, Melancon MP. Stem cell-mediated delivery of SPIO-loaded gold nanoparticles for the theranosis of liver injury and hepatocellular carcinoma. Nanotechnology 25(40):405101, 10/2014. e-Pub 9/2014. PMID: 25211057.

Zhao J, Wallace M, Melancon MP. Cancer Theranostics with Gold Nanoshells. Nanomedicine (Lond) 9(13):2041-57, 9/2014. PMID: 25343352.

Singhana B, Slattery P, Chen A, Wallace MJ, Melancon MP. Light-Activatable Gold Nanoshells for Drug Delivery Applications. AAPS PharmSciTech 15(3):741-52, 6/2014. e-Pub 2/2014. PMID: 24550102.

Melancon MP, Zhou M, Zhang R, Xiong C, Allen P, Wen X, Huang Q, Wallace M, Myers JN, Stafford RJ, Liang D, Ellington AD, Li C. Selective Uptake and Imaging of Aptamer- and Antibody-Conjugated Hollow Nanospheres Targeted to Epidermal Growth Factor Receptors Overexpressed in Head and Neck Cancer. ACS Nano 8(5):4532-8, 5/2014. e-Pub 4/2014. PMID: 24754567.

2013

Lee HJ, Liu Y, Zhao J, Zhou M, Bouchard RR, Mitcham T, Wallace MJ, Stafford RJ, Li C, Gupta S, Melancon MP. In vitro and in vivo mapping of drug release after laser ablation thermal therapy with Doxorubicin-loaded hollow gold nanoshells using fluorescence and photoacoustic imaging. J Control Release 172(1):152-158, 11/2013. NIHMSID: NIHM524047.

2012

Melancon MP, Stafford RJ, Li C. Challenges to effective cancer nanotheranostics. J Control Release 164(2):177-82, 12/2012. e-Pub 8/2012. PMCID: PMC3504179.

You J, Zhang R, Xiong C, Zhong M, Melancon MP, Gupta S, Nick AM, Sood AK, Li C. Effective photothermal chemotherapyusing doxorubicin-loaded gold nanospheres that target EphB4 receptors in tumors. Cancer Res 72(18):4777-4786, 9/2012. e-Pub 8/2012. PMCID: PMC3445780.

Zhang G, Zhang R, Melancon MP, Wong K, You J, Huang Q, Bankson J, Liang D, Li C. The degradation and clearance of Poly(N-hydroxypropyl-L-glutamine)-DTPA-Gd as a blood pool MRI contrast agent. Biomaterials 33(21):5376-83, 7/2012. e-Pub 4/2012. PMCID: PMC3356511.

2011

Melancon MP, Elliott AM, Shetty A, Huang Q, Stafford RJ, Li C. Near-infrared light modulated photothermal effect increases vascular perfusion and enhances polymeric drug delivery. J Control Release 156(2):265-72, 12/2011. e-Pub 7/2011. PMCID: PMC3203335.

Melancon MP, Lu W, Zhong M, Zhou M, Liang G, Elliott AM, Hazle JD, Myers JN, Li C, Stafford RJ. Targeted multifunctional gold-based nanoshells for magnetic resonance-guided laser ablation of head and neck cancer. Biomaterials 32(30):7600-8, 10/2011. e-Pub 7/2011. PMCID: PMC3195359.

Lu W, Melancon MP, Xiong C, Huang Q, Elliott A, Song S, Zhang R, Flores LG, Gelovani JG, Wang LV, Ku G, Stafford RJ, Li C. Effects of photoacoustic imaging and photothermal ablation therapy mediated by targeted hollow gold nanospheres in an orthotopic mouse xenograft model of glioma. Cancer Res 71(19):6116-21, 10/2011. e-Pub 8/2011. PMCID: PMC3185126.

Melancon MP, Zhou M, Li C. Cancer Theranostics with Near-Infrared Light-Activatable Multimodal Nanoparticles. Acc Chem Res 44(10):947-956, 10/2011. e-Pub 8/2011. PMCID: PMC3196765.

Melancon MP, Elliott A, Ji X, Shetty A, Yang Z, Tian M, Taylor B, Stafford RJ, Li C. Theranostics with multifunctional magnetic gold nanoshells: photothermal therapy and t2* magnetic resonance imaging. Invest Radiol 46(2):132-40, 2/2011. PMCID: PMC3435880.

Melancon MP, Li C. Multifunctional synthetic polymer-based therapeutic and diagnostic agents. Mol Imaging 10(1):28-42, 2/2011. PMCID: PMC3435883.

2010

Zhou M, Zhang R, Huang M, Lu W, Song S, Melancon MP, Tian M, Liang D, Li C. A chelator-free multifunctional [64Cu]CuS nanoparticle platform for simultaneous micro-PET/CT imaging and photothermal ablation therapy. J Am Chem Soc 132(43):15351-8, 11/2010. PMCID: PMC2966020.

Melancon MP, Lu W, Huang Q, Thapa P, Zhou D, Ng C, Li C. Targeted imaging of tumor-associated M2 macrophages using a macromolecular contrast agent PG-Gd-NIR813. Biomaterials 31(25):6567-73, 9/2010. PMCID: PMC2900486.

2009

Melancon MP, Lu W, Li C. Gold-Based Magneto/Optical Nanostructures: Challenges for In Vivo Applications in Cancer Diagnostics and Therapy. Mater Res Bull 34(6):415-421, 6/2009. PMCID: PMC2891272.

2008

Melancon MP, Lu W, Yang Z, Zhang R, Cheng Z, Elliot AM, Stafford J, Olson T, Zhang JZ, Li C. In vitro and in vivo targeting of hollow gold nanoshells directed at epidermal growth factor receptor for photothermal ablation therapy. Mol Cancer Ther 7(6):1730-9, 6/2008. PMCID: PMC2727060.

Stafford RJ,  Shetty A,  Elliott AM,  Scwartz J, Melancon MP,  Li C,  Hazle JD. Characterization of Gold Nanoshells for Thermal Therapy Using MRI. Medical Physics 35(6):2937-2938, 6/2008.

2007

Melancon MP, Wang Y, Wen X, Bankson JA, Stephens LC, Jasser S, Gelovani JG, Myers JN, Li C. Development of a macromolecular dual-modality MR-optical imaging for sentinel lymph node mapping. Invest Radiol 42(8):569-78, 8/2007. PMCID: PMC2746745.

Melancon MP, Wang W, Wang Y, Shao R, Ji X, Gelovani JG, Li C. A novel method for imaging in vivo degradation of poly(L-glutamic acid), a biodegradable drug carrier. Pharm Res 24(6):1217-24, 6/2007. e-Pub 3/2007. PMCID: PMC2746742.

2005

Wang W, Wu Q, Pasuelo MJ, McMurray JS, Li C. Probing for integrin alpha v beta3 binding of RGD peptides using fluorescence polarization. Bioconjug Chem 16(3):729-34, May-Jun, 5/2005. PMID: 15898744.

2004

Wen X, Cao X, Pasuelo MJ, Wendt R, Li C. Polymeric radiotracers in nuclear imaging. Curr Drug Deliv 1(4):377-84, 10/2004. PMID: 16305399.

Tansey W, Ke S, Cao XY, Pasuelo MJ, Wallace S, Li C. Synthesis and characterization of branched poly(L-glutamic acid) as a biodegradable drug carrier. J Control Release 94(1):39-51, 1/2004. PMID: 14684270.

2001

Pasuelo MJ , Dayrit FM. Development if quality assurance methods for medicinal plants using gas chromatography analysis. Kimika 17:5-11, 2001.