Development of a radiopaque resorbable inferior vena cava filter infused with nanoparticles
Inferior vena cava (IVC) filters are effective adjunctive therapy for the prevention of pulmonary embolism, a common life-threatening condition in high-risk patients. However, retrieval of conventional IVC filters is problematic with long-term implantation often presenting with complications.
Our laboratory is working on the synthesis and incorporation of nanoparticles in resorbable IVC filters to confer radiopacity; thus, providing a safe, non-invasive, real-time monitoring modality that would mitigate the complications associated with conventional IVC filters.
Our laboratory specializes in optimizing different polymer solutions of varying properties that can
Exploring irreversible electroporation as an adjunct modality in bone tumor treatment
Current approaches to the local control of bone metastasis include radiation therapy and ablative procedures. These
Irreversible electroporation (IRE) is a procedure that delivers short electrical pulses to destroy cancer cells. The technique accomplishes this without generating heat allowing the preservation of healthy tissue matrix. Provided this benefit, our lab is exploring the utility of IRE in combination with drug delivery