Areas of Research
- Radiation Oncology
Dr. Chung leads an imaging computational laboratory within the Department of Radiation Oncology at MD Anderson Cancer Center. Her research focuses on the development of quantitative imaging tools to be used in: 1) tumor response assessment; 2) treatment-related toxicity; and 3) personalization of radiotherapy and multimodal treatment. The Chung lab has established several exciting collaborations across MD Anderson around these research areas. In collaboration with Dr. Davies and Dr. McCarty, we are developing a multidisciplinary approach to understand and improve outcomes in brain metastasis with our project focusing on quantitative imaging measures of tumor response. In collaboration with Dr. Anne Hayman (neuroradiology) and Dr. Rachel Lynn (psychiatry), we are investigating a novel intervention to reduce anxiety around radiation treatment for brain tumors by providing patients and caregivers with personalized neuro-imaging referenced educational videos (funded by the Hackett Foundation). We are also actively examining quantitative imaging and biofluid biomarkers to predict neurocognitive toxicity from brain irradiation in close collaboration with Dr. Wefel that is funded by NASA that has been further supplemented with an internal grant to support changes in resting state fMRI in response to brain radiation exposure in collaboration with Dr. Anthony Liu (CCGS ROCIP Pilot Project award). In collaboration with Dr. Brock, we are also investigating the value of image-guided personalized adaptive radiotherapy for high grade glioma (supported by a Dr. Marnie Rose Foundation grant and IRG). Lastly, we are investigating the role of FAZA-PET and multiparametric MRI to characterize the perfusion, oxygenation and metabolic patterns in gliomas in collaboration with Dr. D. Piwnica-Worms, Dr. F. Wong and Dr. O. Mawlawi (ROSI seed grant).
Chung Laboratory funding is provided by NASA, Alliance for Clinical Trials in Oncology Foundation, Dr. Marnie Rose Foundation, Hackett Family Foundation, CCSG ROCIP and ROSI.