Publications
Baruch EN, Gleber-Netto FO, Nagarajan P, et al. Cancer-induced nerve injury promotes resistance to anti-PD-1 therapy. Nature. 2025 Aug 20:10.1038/s41586-025-09370-8. doi: 10.1038/s41586-025-09370-8. Epub ahead of print. PMID: 40836096; PMCID: PMC12406299
Amit M, Eichwald T, Roger A, et al. Neuro-immune cross-talk in cancer. Nat Rev Cancer. 2025 Aug;25(8):573-589. doi: 10.1038/s41568-025-00831-w. Epub 2025 Jun 16. PMID: 40523971.
Yaniv D, Mattson B, Talbot S, Gleber-Netto FO, Amit M. Targeting the peripheral neural-tumour microenvironment for cancer therapy. Nat Rev Drug Discov. 2024 Oct;23(10):780-796. doi: 10.1038/s41573-024-01017-z. Epub 2024 Sep 6. PMID: 39242781; PMCID: PMC12123372.
Pascual G, Domínguez D, Elosúa-Bayes M, et al. Dietary palmitic acid promotes a prometastatic memory via Schwann cells. Nature 599, 485–490 (2021). https://doi.org/10.1038/s41586-021-04075-0
Amit M, Takahashi H, Dragomir MP, et al. Loss of p53 drives neuron reprogramming in head and neck cancer. Nature. 2020;578(7795):449-454. doi:10.1038/s41586-020-1996-3
Amit M, Na'ara S, Fridman E, et al. RET, a targetable driver of pancreatic adenocarcinoma. Int J Cancer. 2019;144(12):3014-3022. doi:10.1002/ijc.32040
Na'ara S, Amit M, Gil Z. L1CAM induces perineural invasion of pancreas cancer cells by upregulation of metalloproteinase expression. Oncogene. 2019;38(4):596-608. doi:10.1038/s41388-018-0458-y
Na'ara S, Gil Z, Amit M. In Vitro Modeling of Cancerous Neural Invasion: The Dorsal Root Ganglion Model. J Vis Exp. 2016;(110):e52990. Published 2016 Apr 12. doi:10.3791/52990
Amit M, Na'ara S, Gil Z. Mechanisms of cancer dissemination along nerves. Nat Rev Cancer. 2016;16(6):399-408. doi:10.1038/nrc.2016.38
Amit M, Eran A, Billan S, et al. Perineural Spread in Noncutaneous Head and Neck Cancer: New Insights into an Old Problem. J Neurol Surg B Skull Base. 2016;77(2):86-95. doi:10.1055/s-0036-1571834
Shabtay-Orbach A, Amit M, Binenbaum Y, Na'ara S, Gil Z. Paracrine regulation of glioma cells invasion by astrocytes is mediated by glial-derived neurotrophic factor. Int J Cancer. 2015;137(5):1012-1020. doi:10.1002/ijc.29380
Cohen JT, Gil Z, Binenbaum Y, Na'ara S, Amit M. An orthotopic mouse model of laryngeal squamous cell carcinoma. Ann Otol Rhinol Laryngol. 2015;124(2):143-147. doi:10.1177/0003489414549575
Amit M, Binenbaum Y, Trejo-Leider L, et al. International collaborative validation of intraneural invasion as a prognostic marker in adenoid cystic carcinoma of the head and neck. Head Neck. 2015;37(7):1038-1045. doi:10.1002/hed.23710
Cavel O, Shomron O, Shabtay A, et al. Endoneurial macrophages induce perineural invasion of pancreatic cancer cells by secretion of GDNF and activation of RET tyrosine kinase receptor. Cancer Res. 2012;72(22):5733-5743. doi:10.1158/0008-5472.CAN-12-0764
Amit M, Na'ara S, Leider-Trejo L, et al. Upregulation of RET induces perineurial invasion of pancreatic adenocarcinoma. Oncogene. 2017;36(23):3232-3239. doi:10.1038/onc.2016.483