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New M. D. Anderson Study to Help People Stop Smoking & Prevent Weight Gain

New M. D. Anderson Study to Help People Stop Smoking & Prevent Weight Gain
M. D. Anderson News Release 12/19/02

Editor's Note: Recruitment of participants for this study has ended.

Smokers who fear adding a few extra pounds when they quit smoking may have one less reason to postpone kicking the habit.

Researchers at The University of Texas M. D. Anderson Cancer Center are investigating a new drug that may make it easier for smokers to quit, and at the same time, prevent weight gain.

The study, titled "Pharmaceutical Aid to Stop Smoking" or Project PASS, is expected to help people stop smoking, prevent weight gain and reduce cravings and relapse after a person quits. In previous studies, the drug was shown to be effective in treating obesity. This is the first clinical trial to test the drug for the dual benefits of tobacco cessation and prevention of weight gain.

The medication affects mainly chemicals in the brain that are involved in the addictive action of nicotine.

To be eligible for the study, individuals must be age 18 or older, have smoked at least 10 cigarettes daily for the past two months and be in general good health. Only one person per household may participate. Smokers who are eligible to participate take a pill daily for 10 weeks.

Participants begin taking the medication for two weeks before their quit date, and come to M. D. Anderson once a week for the first 12 weeks, provide blood, urine and breath samples, undergo a physical examination and fill out questionnaires. The total study commitment time is one year. Participants receive $25 per visit to M. D. Anderson.

To participate in Project PASS, call (713) 792-2265. 


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