Newly discovered pathway fuels production of cancer-driving proteins
Researchers identified a previously unknown mechanism that helps cancer cells produce cancer-promoting proteins, including KRAS
Blocking a specific enzyme reduced tumor growth in preclinical models of common cancer types
Loss of the enzyme also improved response to KRAS-targeted drugs and counteracted treatment resistance
The findings suggest this enzyme could be a target for KRAS-driven cancers
A previously unknown mechanism helps...
AI tool reveals what attracts immune cells to tumors and what keeps them away
Researchers developed a new artificial intelligence (AI) tool that can help explain where immune cells gather in the body and what guides them...
Researchers suggest tile-based radiation therapy as standard of care to lower risk of recurrence in brain metastases
A type of radiation treatment implanted during surgery (GammaTile) significantly lowers risk of recurrence and may help patients with brain...
Researchers uncover dual role of B7-H3 in tumor immune suppression
Researchers identified a previously unknown pathway for the B7-H3 immune checkpoint that creates a physical defense for prostate tumors
Using a therapy to target B7-H3 along with a MEK inhibitor targeting this pathway produced durable antitumor activity in preclinical models of advanced prostate cancer
Findings uncovered a novel biological function of B7-H3 in cancer immunity
Results suggest a combination approach could overcome treatment...
B cells may help predict risk of colitis from immunotherapy
Colitis, an inflammation of the inner lining of the colon, is a common side effect of immunotherapy that can disrupt treatment
No methods currently...
UT MD Anderson and Nature to co-host conference on next-generation cancer therapeutics
In-person conference runs Oct. 6-8, 2026, with registration open until Oct. 5, 2026
Topics include next-generation cancer therapeutics and immunotherapies...
Blood test could monitor bone metastasis in medullary thyroid cancer
Medullary thyroid cancer often spreads to the bone in advanced disease, causing abnormal bone growth
Researchers discovered the OPG protein...
Psilocybin prevents chemotherapy-related nerve injury and associated symptoms in preclinical models
Peripheral neuropathy is a common side effect of chemotherapy treatment, resulting in symptoms that can include numbness, painful nerve injury...
Researchers identify new way to reduce chronic nerve pain
Study reveals the BRAF protein, commonly linked to cancer, may also drive chronic nerve pain
After nerve injury, BRAF triggers changes that...
Colorectal cancer may quietly damage nerves prior to chemotherapy
Researchers at The University of Texas MD Anderson Cancer Center found that, in preclinical models of colorectal cancer, tumors can start...