Functional Proteomics Reverse Phase Protein Array (RPPA) Core
- Research Resources
- Core Facilities and Services
- Functional Proteomics RPPA Core Facility
Overview
The Functional Proteomics Reverse Phase Protein Array (RPPA) Core provides investigators with a powerful, high throughput, quantitative, cost-effective technology for functional proteomics studies. We provide centralized, standardized and quality-controlled service to investigators throughout MD Anderson and around the world. The RPPA Core has served several national consortia including TCGA, CCLE and ICBP. Learn more about the RPPA Core
Getting Started
- Contact us at ccsgrppa@mdanderson.org or 713-792-5743 for any questions regarding experimental requirements.
- Fill out an iLab service request. The RPPA Core will review the request, and once all information in iLab is correct and complete, will approve the request and provide further instructions for sample submission. More information about how to get started
Impact
The Functional Proteomics Reverse Phase Protein Array (RPPA) Core provides high quality, data rich results for both tumor tissue and cultured cells. RPPA characterizes expression levels of basal and modified proteins as well as growth factor‐ or ligand‐induced effects and time‐resolved responses appropriate for systems biology analyses. RPPA provides information to integrate the consequence of genetic aberrations in cancer, validate therapeutic targets, demonstrate on‐ and off‐target activity of drugs, and evaluate drug pharmacodynamics.
Contact
Phone: 713-792-5743 or 832-750-0145
Email: ccsgrppa@mdanderson.org
Facility Location
6565 MD Anderson Blvd., Room Z4.2040
Houston, Texas 77030
Sample Submission Deadline
We batch process approximately 1,000 samples at a time to keep costs low. Submission deadlines vary based on when we reach capacity. Please contact the core for details on the next deadline.
Submit early — your samples are queued as soon as they arrive.
New Feature
The Cancer Proteome Atlas (TCPA) interactive site for exploring, analyzing, and visualizing RPPA data is fully functional.