Functional Proteomics Reverse Phase Protein Array (RPPA) Core

As part of our ongoing commitment to providing cutting-edge technologies to the research community the Core Facilities Oversight Board (CFOB) has made the decision to close the Functional Proteomics Reverse Phase Protein Array (RPPA) Core Shared Resource Facility. The last sample was processed on May 8, 2026. 

The RPPA Core has been a cornerstone of cancer research at UT MD Anderson and across the global scientific community since its establishment in 2008. Its contributions have been extraordinary: 

• 214,000+ samples analyzed from 1,157 cancer researchers worldwide 
• 1,133+ peer-reviewed publications supported, including in Nature, Cell, Science, and New England Journal of Medicine 
• $20M+ in peer-reviewed grant funding secured from the National Cancer Institute and other agencies 
• ~8,000 samples contributed to The Cancer Genome Atlas (TCGA) across 32 cancer types 
• 1,635+ pan-cancer, biomarker, and multi-omics studies enabled since 2015 
• Development of the automated RPPA Pipeline and integration with The Cancer Proteome Atlas (TCPA) 

We extend our sincerest gratitude to the entire RPPA team — Yiling Lu, M.D. (director), Rehan Akbani, Ph.D. (co-director), Zhenlin Ju, Ph.D., Yan Liu, Doris Rieko Siwak, Ph.D., Qinghua Yu, Shuangxing Yu, and Xinqiao Zhang, Ph.D., — for their years of exceptional service. We are committed to supporting all core personnel through this transition. 

We have taken steps to ensure your research is not interrupted. For assistance identifying vendors offering similar RPPA services, please contact Jared Burks, Ph.D., Executive Director, Shared Resource Technologies.