Lab Members
Principal Investigators
Robert C. Bast, M.D.
Professor of Experimental Therapeutics
Harry Carothers Wiess Distinguished University Chair for Cancer Research
RBast@MDAnderson.org
Dr. Bast received his education at Wesleyan University, Harvard Medical School, Johns Hopkins Hospital, the National Cancer Institute, Peter Bent Brigham Hospital and Dana-Farber Cancer Institute. Before joining the UT MD Anderson faculty in 1994 he served on the faculties of Harvard Medical School and Duke University Medical Center where he was Director of the Duke Comprehensive Cancer Center.
In addition to leading translational research career development, Dr. Bast cares for patients with gynecologic and breast cancer and has been named to Best Doctors in America and America’s Top Physicians. In medical science, Dr. Bast is best known for discovering the CA125 biomarker for ovarian cancer that has contributed to the care of hundreds of thousands of women with ovarian cancer world-wide and promises to provide a critical component of the first effective strategy for early detection of ovarian cancer. His laboratory is attempting to develop a better screening strategy for ovarian cancer, more effective treatment with paclitaxel using targeted therapy and methods to eliminate dormant autophagic cancer cells. Dr. Bast has authored or co-authored more than 750 articles, editorials and chapters and edited the textbook Holland-Frei Cancer Medicine. He has been recognized as a Highly Cited Investigator (top 0.5%) by the Institute for Scientific Information with an H Score of 116. Dr. Bast has mentored more than 85 postdoctoral fellows, visiting investigators, graduate and medical students, and coordinates the Physician-Scientist and Clinician-Investigator Programs at UT MD Anderson.
At a national level, Dr. Bast was a member and chair of the Oncologic Drugs Advisory Committee of the Food and Drug Administration. He has served on three study sections of the National Cancer Institute, as well as scientific advisory committees of 12 NCI-designated US Cancer Centers, the Cancer Center Karolinska, the Deutsche Krebshilfe and the Berlin Institute of Health. He has served as a chair of the tumor markers expert panel of the American Society of Clinical Oncology, and the scientific advisory boards of the V Foundation and Ovarian Cancer Action in the United Kingdom. Dr. Bast also serves on scientific advisory committees for the TJ Martell Foundation and the Ovarian Cancer Research Fund Alliance.
Zhen Lu, M.D.
Professor of Experimental Therapeutics
ZLu@MDAnderson.org
Dr. Lu is an associate member of the UT MD Anderson UTHealth Houston Graduate School of Biomedical Sciences. Dr. Lu earned her master's and M.D. degrees in China, where she was involved with all aspects of teaching. She moved to the United States and obtained her second master's degree in biology from University of Memphis. Since moving to Houston in 2002, she has been an active member in Dr. Bast’s group, where her research aims to elucidate the function of ARHI (DIRAS3) and develop novel therapeutic approaches for ovarian cancer. In collaboration with Dr. Bast, Dr. Lu provides guidance to all trainees in the research group.
Dr. Lu’s research has focused on ovarian cancer tumorigenesis and function of tumor suppressors. Our group has identified ARHI (DIRAS3), an imprinted tumor suppressor gene that is downregulated in 60% of ovarian cancers. Re-expression of ARHI blocks cell growth, inhibits motility, induces autophagy and establishes tumor dormancy. By re-expressing ARHI from a doxycycline-inducible promoter in ovarian cancer xenografts, Dr. Lu developed the first inducible model for tumor dormancy in ovarian cancer, permitting evaluation of novel anti-autophagic therapy to eliminate dormant ovarian cancer cells. In addition to studying tumor dormancy, Dr. Lu has also identified key regulators of paclitaxel resistance, and novel biomarkers for the early detection of ovarian cancer. Over the last 17 years, Dr. Lu has served as co-investigator and co-principal investigator on numerous NIH-funded grants and has published more than 40 peer-reviewed articles.
Research Staff
Hailing Yang, Ph.D.
Senior Research Scientist
2011–present
HYang3@MDAnderson.org
Dr. Hailing Yang earned her Ph.D. from the UT MD Anderson UTHealth Houston Graduate School of Biomedical Sciences. Her project focuses on the treatment of ovarian cancer using kinase inhibitors.
Weiqun (Maggie) Mao, B.S.
Research Investigator
2004–present
WMao@MDAnderson.org
Ms. Mao is a Research Investigator who has been a valued member of Dr. Bast's cancer research lab at UT MD Anderson for the past 20 years. She received her Bachelor of Science degree in engineering from Tongji University in Shanghai, China, before moving to the United States to pursue cancer research.
In addition to her expertise in running various assays and experiments in the lab, Ms. Mao plays a pivotal role in training new lab members, ensuring they learn proper techniques and lab safety protocols. She helps troubleshoot experiments and serves as a technical mentor for younger researchers.
Ms. Mao actively contributes to several key, ongoing research projects. She is currently investigating novel SIK2 inhibitors that may enhance the efficacy of chemotherapy and immunotherapy in ovarian cancer and triple-negative breast cancer (TNBC). Her research involves in vitro and in vivo studies to elucidate the mechanisms and optimize combinations/dosing to tackle chemoresistance.
Gamze Bildik Elcik, Ph.D.
Instructor
2019–present
GBildik@MDAnderson.org
Dr. Bildik received her B.S. in molecular biology and genetics from Istanbul University, Turkey, and her M.S. in reproductive biology from Koc University, where she trained in a translational research laboratory focusing on fertility preservation strategies against ovarian damage induced by chemotherapy and radiation in young female cancer survivors. She earned her Ph.D. in cellular and molecular medicine from Koc University, completing her thesis on uncovering the molecular mechanisms behind DNA damage-induced and TAp63-mediated oocyte apoptosis in the human ovary.
In 2019, Dr. Bildik joined UT MD Anderson as a TRIUMPH Postdoctoral Fellow. Since April 2024, she has been working as an Instructor. Her research focuses on overcoming MEK inhibitor resistance in low-grade serous ovarian cancer, with an emphasis on understanding autophagy-mediated drug resistance and developing more effective therapeutic strategies. She is also interested in studying rare ovarian cancers to identify novel therapeutic approaches for these understudied diseases.
Carlos Perfecto Flores Suarez
Postdoctoral Fellow
2024–present
CPFlores1@MDAnderson.org
Carlos earned his B.S. in biology from Universidad Peruana Cayetano Heredia in Lima, Peru. He then earned his Ph.D. in molecular physiology and biophysics from Baylor College of Medicine. Finally, Carlos joined the TRIUMPH Postdoctoral Fellowship Program in March 2024. His work focuses on the study of breast and RAS-driven cancers. His current projects aim to investigate the role of SIK2 inhibitors to enhance immunotherapy in breast cancer and to optimize the design and delivery of DIRAS3 stapled peptides in order to enhance their stability, cellular uptake and anti-cancer efficacy in RAS-derived cancers.
Cuipeng (Autumn) Qiu
Postdoctoral Fellow
2025–present
CQiu2@MDAnderson.org
Dr. Cuipeng Qiu earned her B.Med. and M.P.H. degrees in China. She obtained her Ph.D. in biological sciences at The University of Texas at El Paso in 2024. Then she joined Dr. Bast’s lab as a postdoctoral fellow in 2025. Her research focuses on identifying diagnostic and prognostic biomarkers for ovarian cancer. The goal of her project is to develop a multi-biomarker panel for the early detection of ovarian cancer.
Oliver H. Wang, B.A.
Research Assistant II
2023–present
OWang@MDAnderson.org
Mr. Wang earned his bachelor's in English literature with a concentration in creative writing from Washington University in St. Louis. His work previously involved the replication of the tumor microenvironment in transgenic dual-recombinase mouse models.
Alumni
Faculty & Staff
Abou Ghalia, Azza
Bae, Duk Soo
Boente, Matthew
Bregni, Marco
DeFabritiis, Paolo
Deutsch, Margaret
Fayed, Salah
Haleem, Azeem
Havrilesky, Laura
Hunter, Verda
Hurteau, Jean
Introna, Martino
Kamel, Ahmed
Kassim, Samar
Kohler, Matthew
Laforge, Sophie
Lee, Joon-Mo
Lien, Mary
Lottich, Chase
Orellana, Vivian R. – Faculty Research Assistant
Pang, Lan – Faculty Research Assistant
Rask, Philip – Faculty Research Assistant
Ren, Wenhong – Faculty Research Assistant
Rodriguez, Gus
Shah, Shafqat
Soisson, Andrew Patrick
Tran, Samantha – Faculty Research Assistant
Tyson, Fred
Wang, Yan – Faculty Research Assistant
Wu, Shu
Yang, Maojie – Faculty Research Assistant
Medical Students
Aiken, Abbie, M.D. (2008, UT MD Anderson)
Anderson, Ian M.D. (1988, Duke University Medical Center)
Atashroo, Diana, M.D. (2005, UT MD Anderson)
Chen, Teresa, M.D. (2003, UT MD Anderson)
Chrysson, Nick M.D. (1988, Duke University Medical Center)
Crews, Jennie M.D. (1989, Duke University Medical Center)
Dabal, Robert M.D. (1993, Duke University Medical Center)
Dean, Scott M.D. (1991, Duke University Medical Center)
Dimsdale, Jason M.D. (1991, Duke University Medical Center)
Haleem, Azeem M.D. (1985, Duke University Medical Center)
Havrilesky, Laura M.D. (1994, Duke University Medical Center)
Karlan, Beth M.D. (1983, Dana-Farber Cancer Institute)
Klotz, Daniel, M.D. (2015, UT MD Anderson)
Lien, Mary M.D. (1991, Duke University Medical Center)
Lipska, Beata Stefania, M.D. (2002, UT MD Anderson)
Maier, Lisa M.D. (1990, Duke University Medical Center)
Montgomery, Bruce M.D. (1986, Duke University Medical Center)
Mullen, Mary M.D. (1984, Dana-Farber Cancer Institute)
Pruefer, Franz, M.D. (2001, UT MD Anderson)
Rodabaugh, Kerry M.D. (1989, Duke University Medical Center)
Shah, Shafqat M.D. (1990, Duke University Medical Center)
Silva, Orlando – M.S.
Varela, Carly L., M.D. (1999, UT MD Anderson)
Postdoctoral Research Fellows
Albandri, Alfraidi, Ph.D. (2012–2013)
Ashour Ahmed, Ahmed M.D., Ph.D. (2008–2010)
Badgwell, Donna, Ph.D. (2005–2008)
Baquero, Maria, Ph.D. (2011–2012)
Bezorgi, Kenny, M.D. (1996–1997)
Bildick, Gamze, Ph.D (2019)
Blessing, Alicia, Ph.D. (2016–2019)
Chen, Min-Yu, M.D. (2005–2008)
Dalrymple, John, M.D. (1995–1996)
Das, Partha M.D. (2006–2009)
Diaz, Sheridan, M.D. (1995–1996)
Fan, Dengxuan, M.D. (2018–2019)
Feng, Weiwei, M.D. (2004–2006)
Flores Suarez, Carlos, Ph.D. (2024–Present)
Frumovitz, Michael, M.D. (2001–2002)
Fujii, Satoshi, M.D. (2001–2002)
Gray, Josh, Ph.D. (2021)
Guo, Jing, M.D. (2017–2019)
Hagopian, George, M.D. (1996–1998)
Ho Lee, Keun, M.D. (2007–2009)
Huang, Gilbert, Ph.D. (2015–2019)
Kramer, Stefan, M.D. (2000)
Kruzelock, Rusty, Ph.D. (1995–1998)
Liang, Xiaowen, Ph.D. (2019–2021)
Nishimoto, Arata, Ph.D. (2002–2003)
Ozyurt, Rumeysa, Ph.D. (2022–Present)
Pastelnik, Terry, Ph.D. (1996–1997)
Peters, Haley (2012–2013)
Pusztai, Lajos, M.D., Ph.D. (1997-1998)
Qiu, Cuipeng “Autumn” (2025–Present)
Raamanathan, Archana, Ph.D. (2011–2014)
Romero Noguera, Ignacio M.D., Visiting Physician (2011)
Santiago-O'Farrell, Janice, Ph.D. (2015–2020)
Suh, Grace, M.D. (2008–2010)
Sutton, Margie Nicole, Ph.D. (2018–2022)
Wang, Lin, M.D. (2001–2002)
Wang, Xiaoyan, M.D. (2009–2010)
Washington, Michele, Ph.D. (2009–2011)
Wen, Xian-Feng, M.D. (2003–2005)
Yang, Hailing, Ph.D (2011–2015)
Yang, Wei-Lei “William” (2014–2019)
Young Han, Chae, Ph.D. (2019)
Yuan, Jiuhong, M.D. (2000–2001)
Zhang, Shu, M.D., Visiting Physician (2010–2011)
Zhou, Jinhua, Ph.D. (2014–2016)
Postdoctoral Advisory Committees, TRIUMPH Scholars
Alexander, Angela (2008–2011) — TRIUMPH
Baljevic, Muhamed (2016)
Cheondd, Dong-Joo (2007–2010)
Dennison, Jennifer (2009–2012) — TRIUMPH
Dettler, Jamie (2011–2012) — TRIUMPH
Gomez-Chou, Sobeyda (2012)
Gray, Joshua (2016–2020)
Huang, Gilbert (2016)
Hubert, Leroy (2012–2013)
Izaguirre, Daisy (2016)
Jabbour, Natalie (2011)
Karuturi, Meghan Sri (2014)
Kivlin, Michelle (2016)
Lara-Guerra, Humberto (2011) — TRIUMPH
Loupot, Sara (2016)
Mastoraki, Sophia (2020) — TRIUMPH
McKenzie, Jodi (2013) — TRIUMPH
Min Lee, Hey (2018)
Mitri, Zahi (2016)
Mohammad, Abdalah, M.D. (2018–2021)
Napoli, Marco (2016)
Orozco, Aaron (2011–2012) — TRIUMPH
Patel, Krina (2016)
Pickering, Curtis (2008–2011) — TRIUMPH
Sanchez, Nora (2013) — TRIUMPH
Scaduto, Diane (2011) — TRIUMPH
Su, Chun-Hui (2011) — TRIUMPH
Thomas, Ann (2011–2013) — TRIUMPH
Thrower, Sarah L. (2017–2018)
Vijayaraghavan, Smruthi (2016)
Wu, Sherry (2011) — TRIUMPH
Yang, Dong (2011) — TRIUMPH
Graduate Students
Cheon, Dong-Joo (2007–2010)
Dong, Wenli (2004)
Figueroa, Mary (2016)
Ho, I-Lin (2017)
Mondal, Jayanta (2019)
Peiton, Jarmon (Summer 2022)
Sutton, Margie Nicole (2012–2017)
Undergraduate and Allied Health Students
Banerjee, Anikait (Oni) (Summer 2023)
Becker, Sarah Elizabeth (Summer 2019)
Elmir, Ezzeddine (2018)
Fu, Caroline (2011)
Hamilton, Kirsten (Summer 2022 UPWARDS Undergraduate Student)
Kim, Noori, M.D. (2003)
Knudsen, Hannah Rose (Summer 2019)
Pontikos, Michael (2011)
Svetlitski, Jessica (Summer 2023)
Watowich, Matthew (Summer 2020)
Zakeri, Aran (Summer 2023 Student CPRIT CURE)
Visiting Scientists
Jacobs, Ian, M.D. (1991–1992)
Lido, Yaron, M.D. (1987–1989)
Masuho, Yasuhiko, Ph.D. (1982–1983)
Moongkarndi, Primchanien, Pharm.D. (1992–1994)
Negrier, Silvie, M.D. (1993–1994)
Obrist, Rito, M.D. (1981–1982)
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Research Areas
Find out about the four types of research taking place at UT MD Anderson.