Selected Publications

Wang L, Wang X, Li Y, Han S, Zhu J, Wang X, Molkentine DP, Blanchard P, Yang Y, Zhang R, Sahoo N, Gillin M, Zhu XR, Zhang X, Myers JN, Frank SJ*. Human papillomavirus status and the relative biological effectiveness of proton radiotherapy in head and neck cancer cells. Head Neck 2017;39(4):708-715.

Wang L, Han S, Zhu J, Wang X, Li Y, Wang Z, Lin E, Wang X, Molkentine DP, Blanchard P, Yang Y, Zhang R, Sahoo N, Gillin M, Zhu XR, Zhang X, Myers JN, Frank SJ*. Proton versus photon radiation-induced cell death in head and neck cancer cells. Head Neck 2019;41(1):46-55.

Lindemann A, Patel AA, Silver NL, Tang L, Liu Z, Wang L, Tanaka N, Rao X, Takahashi H, Maduka NK, Zhao M, Chen TC, Liu W, Gao M, Wang J, Frank SJ, Hittelman WN, Mills GB, Myers JN, Osman AA. COTI-2, A Novel Thiosemicarbazone Derivative, Exhibits Antitumor Activity in HNSCC through p53-dependent and -independent Mechanisms. Clin Cancer Res. 2019;25(18):5650-5662. 

Wang L, Yang L, Han S, Zhu J, Li Y, Wang Z, Fan YH, Lin E, Zhang R, Sahoo N, Li Y, Zhang X, Wang X, Li T, Zhu XR, Zhu H, Heymach JV, Myers JN, Frank SJ*. Patterns of protein expression in human head and neck cancer cell lines differ after proton vs photon radiotherapy. Head Neck 2020;42(2):289-301.

Wang L, Cao J, Wang X, Lin E, Wang Z, Li Y, Li Y, Chen M, Wang X, Jiang B, Zhang R, Sahoo N, Zhang X, Zhu XR, Myers JN, Frank SJ*. Proton and photon radiosensitization effects of niraparib, a PARP-1/-2 inhibitor, on human head and neck cancer cells. Head Neck 2020;42(9):2244-2256.

Uzunparmak B, Gao M, Lindemann A, Erikson K, Wang L, Lin E, Frank SJ, Gleber-Netto FO, Zhao M, Skinner HD, Newton J, Sikora AG, Myers JN, Pickering CR. Caspase-8 loss radiosensitizes head and neck squamous cell carcinoma to SMAC mimetic-induced necroptosis. JCI Insight. 2020;5(23):e139837.

Hang Q, Zeng L, Wang L, Nie L, Yao F, Teng H, Deng Y, Yap S, Sun Y, Frank SJ, Chen J, Ma L. Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance. Nat Commun. 2021;12(1):4033.

Lindemann A, Patel AA, Tang L, Tanaka N, Gleber-Netto FO, Bartels MD, Wang L, McGrail DJ, Lin SY, Frank SJ, Frederick MJ, Myers JN, Osman AA. Combined Inhibition of Rad51 and Wee1 Enhances Cell Killing in HNSCC Through Induction of Apoptosis Associated With Excessive DNA Damage and Replication Stress. Mol Cancer Ther. 2021;20(7):1257-1269.

Wang L, Fossati P, Paganetti H, Ma L, Gillison M, Myers JN, Hug E, Frank SJ*. The Biological Basis for Enhanced Effects of Proton Radiation Therapy Relative to Photon Radiation Therapy for Head and Neck Squamous Cell Carcinoma. Int J Part Ther. 2021; 8(1):3-13.

Holliday E, Bhattasali O, Kies MS, Hanna E, Garden AS, Rosenthal DI, Morrison WH, Gunn GB, Phan J, Zhu R, Zhang X, Frank SJ*. Postoperative Intensity-Modulated Proton Therapy for Head and Neck Adenoid Cystic Carcinoma. Int J Part Ther. 2016;2(4):533-543.

Bhattasali O, Holliday E, Kies MS, Hanna EY, Garden AS, Rosenthal DI, Morrison WH, Gunn GB, Fuller CD, Zhu XR, Frank SJ*. Definitive proton radiation therapy and concurrent cisplatin for unresectable head and neck adenoid cystic carcinoma: A series of nine cases and a critical review of the literature. Head Neck. 2016;38 Suppl 1:E1472-80.

Lewis GD, Holliday EB, Kocak-Uzel E, Hernandez M, Garden AS, Rosenthal DI, Frank SJ*. Intensity-modulated proton therapy for nasopharyngeal carcinoma: Decreased radiation dose to normal structures and encouraging clinical outcomes. Head Neck. 2016;38 Suppl 1:E1886-95.

Holliday EB, Esmaeli B, Pinckard J, Garden AS, Rosenthal DI, Morrison WH, Kies MS, Gunn GB, Fuller CD, Phan J, Beadle BM, Zhu XR, Zhang X, Frank SJ*. A Multidisciplinary Orbit-Sparing Treatment Approach that Includes Proton Therapy for Epithelial Tumors of the Orbit and Ocular Adnexa. Int J Radiat Oncol Biol Phys 2016;95(1):344-52.

Gunn GB, Blanchard P, Garden AS, Zhu XR, Fuller CD, Mohamed ASR, Morrison WH, Phan J, Beadle BM, Skinner HD, Sturgis EM, Kies MS, Hutcheson KA, Rosenthal DI, Mohan R, Gillin MT, Frank SJ*. Clinical outcomes and patterns of disease recurrence following intensity modulated proton therapy for oropharyngeal squamous carcinoma. Int J Radiat Oncol Biol Phys, 2016;95(1):360-367.

Sio TT, Lin HK, Shi Q, Gunn GB, Cleeland CS, Lee JJ, Hernandez M, Blanchard P, Thaker NG, Phan J, Rosenthal DI, Garden AS, Morrison WH, Fuller CD, Mendoza TR, Mohan R, Wang XS, Frank SJ*. Intensity Modulated Proton Therapy Versus Intensity Modulated Photon Radiation Therapy for Oropharyngeal Cancer: First Comparative Results of Patient-Reported Outcomes. Int J Radiat Oncol Biol Phys 2016;95(4):1107-14.

Blanchard P, Garden AS, Gunn GB, Rosenthal DI, Morrison WH, Hernandez M, Crutison J, Lee JJ, Ye R, Fuller CD, Mohamed AS, Hutcheson KA, Holliday EB, Thaker NG, Sturgis EM, Kies MS, Zhu XR, Mohan R, Frank SJ*. Intensity-modulated proton beam therapy (IMPT) versus intensity-modulated photon therapy (IMRT) for patients with oropharynx cancer - A case matched analysis. Radiother Oncol 2016;120(1):48-55.

Sio T, Lin H, Shi Q, Gunn GB, Cleeland C, Lee JJ, Hernandez M, Blanchard P, Thaker NG, Phan J, Rosenthal DI, Garden AS, Morrison WH, Fuller CD, Mendoza TR, Mohan R, Wang XS, Frank SJ*. Intensity-Modulated Proton Therapy (IMPT) versus Intensity-Modulated Photon Radiotherapy (IMRT) for Oropharyngeal Cancer: First Comparative Results of Patient-Reported Outcomes. Int J Radiat Oncol Biol Phys, 2016;95(4):1107-14.

Esmaeli B, Yin VT, Hanna EY, Kies MS, William WN, Bell D, Frank SJ*. Eye-sparing multidisciplinary approach for the management of lacrimal gland carcinoma. Head Neck 2016;38(8):1258-62.

McKeever MR, Sio TT, Gunn GB, Holliday EB, Blanchard P, Kies MS, Weber RS, Frank SJ*. Reduced acute toxicity and improved efficacy from intensity-modulated proton therapy (IMPT) for the management of head and neck cancer. Chin Clin Oncol 2016;5(4):54.

Phan J, Sio TT, Nguyen TP, Takiar V, Gunn GB, Garden AS, Rosenthal DI, Fuller CD, Morrison WH, Beadle B, Ma D, Zafereo ME, Hutcheson KA, Kupferman ME, William WN, Frank SJ*. Reirradiation of Head and Neck Cancers with Proton Therapy: Outcomes and Analyses. Int J Radiat Oncol Biol Phys 2016;96(1):30-41.

Blanchard P, Wong AJ, Gunn GB, Garden AS, Mohamed AS, Rosenthal DI, Crutison J, Wu R, Zhang X, Zhu XR, Mohan R, Amin MV, Fuller CD, Frank SJ*. Toward a model-based patient selection strategy for proton therapy: External validation of photon-derived normal tissue complication probability models in a head and neck proton therapy cohort. Radiother Oncol. 2016;121(3):381-386.

Blanchard P, Volk RJ, Ringash J, Peterson SK, Hutcheson KA, Frank SJ*. Assessing head and neck cancer patient preferences and expectations: A systematic review. Oral Oncol 2016;62:44-53.

Holliday EB, Kocak-Uzel E, Feng L, Thaker NG, Blanchard P, Rosenthal DI, Gunn GB, Garden AS, Frank SJ*. Dosimetric advantages of intensity modulated proton therapy for oropharyngeal cancer compared with intensity-modulated radiation: A case-matched control analysis. Med Dosim 2016;41(3):189-94.

Zhang W, Zhang X, Yang P, Blanchard P, Garden AS, Gunn B, Fuller CD, Chambers M, Hutcheson KA, Ye R, Lai SY, Radwan MAS, Zhu XR, Frank SJ*. Intensity-modulated proton therapy and osteoradionecrosis in oropharyngeal cancer. Radiother Oncol 2017;123(3):401-405.

Blanchard P, Gunn GB, Lin A, Foote RL, Lee NY, Frank SJ. Proton Therapy for Head and Neck Cancers. Semin Radiat Oncol 2018;28(1):53-63.

Frank SJ, Blanchard P, Lee JJ, Sturgis EM, Kies MS, Machtay M, Vikram B, Garden AS, Rosenthal DI, Gunn GB, Fuller CD, Hutcheson K, Lai S, Busse PM, Lee NY, Lin A, Foote RL. Comparing Intensity-Modulated Proton Therapy with Intensity-Modulated Photon Therapy for Oropharyngeal Cancer: The Journey From Clinical Trial Concept to Activation. Semin Radiat Oncol 2018;28(2):108-113.

Wu RY, Liu AY, Yang J, Williamson TD, Wisdom PG, Bronk L, Gao S, Grosshan DR, Fuller DC, Gunn GB, Ronald Zhu X, Frank SJ*. Evaluation of the accuracy of deformable image registration on MRI with a physical phantom. J Appl Clin Med Phys 2020;21(1):166-173.

Pasalic D, Ludmir EB, Allen PK, Thaker NG, Chapman BV, Hanna EY, Su SY, Ferrarotto R, Glisson BS, Reddy JP, Brandon Gunn G, Fuller CD, Phan J, Rosenthal DI, Morrison WH, Garden AS, Frank SJ*. Patient-Reported Outcomes, Physician-Reported Toxicities, and Treatment Outcomes in a Modern Cohort of Patients with Sinonasal Cancer Treated Using Proton Beam Therapy. Radiother Oncol 2020;148:258-266.

Grant SR, Hutcheson KA, Ye R, Garden AS, Morrison WH, Rosenthal DI, Brandon Gunn G, Fuller CD, Phan J, Reddy JP, Moreno AC, Lewin JS, Sturgis EM, Ferrarotto R, Frank SJ*. Prospective longitudinal patient-reported outcomes of swallowing following intensity modulated proton therapy for oropharyngeal cancer. Radiother Oncol 2020;148:133-139.

Cao J, Zhang X, Jiang B, Chen J, Wang X, Wang L, Sahoo N, Zhu XR, Ye R, Blanchard P, Garden AS, Fuller CD, Gunn GB, Frank SJ*. Intensity-modulated proton therapy for oropharyngeal cancer reduces rates of late xerostomia. Radiother Oncol. 2021 Jul; 160:32-39.

Smith GL, Shih YT, Frank SJ*. Financial Toxicity in Head and Neck Cancer Patients Treated With Proton Therapy. Int J Part Ther. 2021; 8(1):366-373.

Bahig H, Gunn BG, Garden AS, Ye R, Hutcheson K, Rosenthal DI, Phan J, Fuller CD, Morrison WH, Reddy JP, Ng SP, Gross ND, Sturgis EM, Ferrarotto R, Gillison M, Frank SJ*. Patient-Reported Outcomes after Intensity-Modulated Proton Therapy for Oropharynx Cancer. Int J Part Ther. 2021; 8(1):213-222.

Lin A, Chang JHC, Grover RS, Hoebers FJP, Parvathaneni U, Patel SH, Thariat J, Thomson DJ, Langendijk JA, Frank SJ*. PTCOG Head and Neck Subcommittee Consensus Guidelines on Particle Therapy for the Management of Head and Neck Tumors. Int J Part Ther. 2021; 8(1):84-94.

Sherry AD, Pasalic D, Gunn GB, Fuller CD, Phan J, Rosenthal DI, Morrison WH, Sturgis EM, Gross ND, Gillison ML, Ferrarotto R, El-Naggar AK, Garden AS, Frank SJ*. Proton Beam Therapy for Head and Neck Carcinoma of Unknown Primary: Toxicity and Quality of Life. Int J Part Ther. 2021; 8(1):234-247.

Gunn GB, Garden AS, Ye R, Ausat N, Dahlstrom KR, Morrison WH, Fuller CD, Phan J, Reddy JP, Shah SJ, Mayo LL, Chun SG, Chronowski GM, Moreno AC, Myers JN, Hanna EY, Esmaeli B, Gillison ML, Ferrarotto R, Hutcheson KA, Chambers MS, Ginsberg LE, El-Naggar AK, Rosenthal DI, Zhu XR, Frank SJ*. Proton Therapy for Head and Neck Cancer: A 12-Year, Single-Institution Experience. Int J Part Ther. 2021; 8(1):108-118.

Frank, SJ*, Das, IJ, Simone, C, Davis, BJ, Deville, C, Liao, Z, Lo, SS, McGovern, SL, Parikh, RR, Reilly, M, Small, W, Schechter, NR. ACR-ARS Practice Parameter for the Performance of Proton Beam Therapy. Int J Part Ther. 2024; 13.

Parker PA, Davis JW, Latini DM, Baum G, Wang X, Ward JF, Kuban D, Frank SJ, Lee AK, Logothetis CJ, Kim J. Relationship between illness uncertainty, anxiety, fear of progression and quality of life in men with favourable-risk prostate cancer undergoing active surveillance. BJU Int 2016;117(3):469-77.

Thaker NG, Pugh TJ, Mahmood U, Choi S, Spinks TE, Martin NE, Sio TT, Kudchadker RJ, Kaplan RS, Kuban DA, Swanson DA, Orio PF, Zelefsky MJ, Cox BW, Potters L, Buchholz TA, Feeley TW, Frank SJ*. Defining the Value Framework for Prostate Brachytherapy using Patient-Centered Outcome Metrics and Time-Driven Activity-Based Costing. Brachytherapy 2016;15(3):274-82.

Lim TY, Kudchadker RJ, Wang J, Bathala T, Szklaruk J, Pugh TJ, Mahmood U, Ibbott GS,  Frank SJ*. Development of a magnetic resonance imaging protocol to visualize encapsulated contrast agent markers in prostate brachytherapy recipients: Initial patient experience. J Contemp Brachytherapy 2016;8(3):235-42.

Davis JW, Ward JF, Pettaway CA, Wang X, Kuban D, Frank SJ, Lee AK, Pisters LL, Matin SF, Shah JB, Karam JA, Chapin BF, Papadopoulos JN, Achim M, Hoffman KE, Pugh TJ, Choi S, Troncoso P, Logothetis CJ, Kim J. Disease reclassification risk with stringent criteria and frequent monitoring in men with favourable-risk prostate cancer undergoing active surveillance. BJU Int 2016;118(1):68-76.

Lim TY, Kudchadker RJ, Wang J, Stafford RJ, MacLellan C, Rao A, Ibbott GS, Frank SJ*. Effect of pulse sequence parameter selection on signal strength in positive-contrast MRI markers for MRI-based prostate post-implant assessment. Med Phys 2016;43(7):4312.

Wang J, Weygand J, Hwang KP, Mohamed AS, Ding Y, Fuller CD, Lai SY,  Frank SJ, Zhou J. Magnetic Resonance Imaging of Glucose Uptake and Metabolism in Patients with Head and Neck Cancer. Sci Rep 2016;6:30618.

Pugh TJ, MD1; Choi S, MD2; Nogueras-Gonzalaez GM, MPH3; Nguyen QN, Mahmood U, Frank SJ, Mathai B, Zhu XR, Sahoo N, Gillin M, Kuban D, Hoffman K, McGuire S, Lee A. Proton Beam Therapy for Localized Prostate Cancer: Results from a Prospective Quality-of-Life Trail. Int J Part Ther 2016;3(1):27-36.

Bian SX, Kuban DA, Levy LB, Oh J, Choi S, McGuire SE, Frank SJ, Mahmood U, Nguyen PL, Pugh TJ, Lee AK, Hoffman KE. The Influence of Age and Comorbidity on the Benefit of Adding Androgen Deprivation to Dose-Escalated Radiation in Men With Intermediate-Risk Prostate Cancer. Am J Clin Oncol 2016;39(4):368-73.

Thaker NG, Ali TN, Porter ME, Feeley TW, Kaplan RS, Frank SJ*. Communicating Value in Healthcare Using Radar Charts: A Case Study of Prostate Cancer. J Oncol Pract 2016;12(9):813-20.

Hoffman KE, Skinner H, Pugh TJ, Voong KR, Levy LB, Choi S, Frank SJ, Lee AK, Mahmood U, McGuire SE, Schlembach PJ, Du W, Johnson J, Kudchadker RJ, Kuban DA. Patient-reported Urinary, Bowel and Sexual Function After Hypofractionated Intensity-Modulated Radiation Therapy for Prostate Cancer: Results From a Randomized Trial. Am J Clin Oncol 2016;41(6).

Wang L, Hoogcarspel SJ, Wen Z, Van Vulpen M, Molkentine DP, Kok J, Lin SH, Broekhuizen R, Ang KK, Bovenschen N, Raaymakers BW, Frank SJ*. Biological responses of human solid tumor cells to X-ray irradiation within a 1.5-Tesla magnetic field generated by a magnetic resonance imaging-linear accelerator. Bioelectromagnetics 2016;37(7):471-80.

Moghanaki D, Turkbey B, Vapiwala N, Ehdaie B, Frank SJ, McLaughlin PW, Harisinghani M. Advances in Prostate Cancer Magnetic Resonance Imaging and Positron Emission Tomography-Computed Tomography for Staging and Radiotherapy Treatment Planning. Semin Radiat Oncol 2017;27(1):21-33.

Keyes M, Merrick G, Frank SJ, Grimm P, Zelefsky MJ. American Brachytherapy Society Task Group Report: Use of androgen deprivation therapy with prostate brachytherapy – A systematic literature review. Brachytherapy 2017;16(2):245-265.

Blanchard P, Ménard C, Frank SJ*. Clinical use of magnetic resonance imaging across the prostate brachytherapy workflow. Brachytherapy 2017;16(4):734-742.

Ma J, Moerland MA, Venkatesan AM, Bathala TK, Kudchadker RJ, Brock KK, Frank SJ*. Pulse sequence considerations for simulation and postimplant dosimetry of prostate brachytherapy. Brachytherapy 2017;16(4):743-753.

Voong KR, Lal LS, Kuban DA, Pugh TJ, Swint JM, Godby J, Choi S, Lee AK, Schlembach PJ, Frank SJ, McGuire SE, Hoffman KE. Long-term economic value of hypofractionated prostate radiation: Secondary analysis of a randomized trial. Adv Radiat Oncol 2017;2(3):249-258.

Martin GV, Pugh TJ, Mahmood U, Kudchadker RJ, Wang J, Bruno TL, Bathala T, Blanchard P, Frank SJ*. Permanent prostate brachytherapy postimplant magnetic resonance imaging dosimetry using positive contrast magnetic resonance imaging markers. Brachytherapy 2017;16(4):761-769.

Martin GV, Pugh TJ, Mahmood U, Kudchadker RJ, Wang J, Bruno TL, Bathala T, Frank SJ*. Permanent prostate brachytherapy pubic arch evaluation with diagnostic magnetic resonance imaging. Brachytherapy 2017;16(4):728-733.

Jackson MW, Amini A, Jones BL, Kavanagh B, Maroni P, Frank SJ, Mahmood U, Kudchadker RJ, Pugh TJ. Prostate brachytherapy, either alone or in combination with external beam radiation, is associated with longer overall survival in men with favorable pathologic Group 4 (Gleason score 8) prostate cancer. Brachytherapy 2017;16(4):790-796.

Frank SJ, Mourtada F, Crook J, Menard C. Use of magnetic resonance imaging in low-dose-rate and high-dose-rate prostate brachytherapy from diagnosis to treatment assessment: Defining the knowledge gaps, technical challenges, and barriers to implementation. Brachytherapy 2017;16(4):672-678.

Maenhout M, Peters M, Van Vulpen M, Moerland MA, Meijer RP, Van Den Bosch MAAJ, Nguyen PL, Frank SJ, Van Der Voort Van Zyp JRN. Focal MRI-Guided Salvage High-Dose-Rate Brachytherapy in Patients With Radiorecurrent Prostate Cancer. Technol Cancer Res Treat 2017;16(6):1194-1201.

Maenhout M, Frank SJ*. Second salvage HDR brachytherapy for radiorecurrent prostate cancer. J Contemp Brachytherapy 2017;9(2):161-166.

Holliday E, Kuban D, Levy L, Bolukbasi Y, Master P, Choi S, Nguyen Q, McGuire S, Mahmood U, Frank SJ, Hoffman K. Select men benefit from androgen deprivation therapy delivered with salvage radiation therapy after prostatectomy. Prostate Cancer Prostatic Dis 2017;20(4):389-394.

Pathmanathan AU, van As NJ, Kerkmeijer LGW, Christodouleas J, Lawton CAF, Vesprini D, van der Heide UA, Frank SJ, Nill S, Oelfke U, van Herk M, Li XA, Mittauer K, Ritter M, Choudhury A, Tree AC. Magnetic Resonance Imaging-Guided Adaptive Radiation Therapy: A "Game Changer" for Prostate Treatment? Int J Radiat Oncol Biol Phys 2018;100(2):361-373.

Frank SJ, Pugh TJ, Blanchard P, Mahmood U, Graber WJ, Kudchadker RJ, Davis JW, Kim J, Choi H, Troncoso P, Kuban DA, Choi S, McGuire S, Hoffman KE, Chen HC, Wang X, Swanson DA. Prospective Phase 2 Trial of Permanent Seed Implantation Prostate Brachytherapy for Intermediate-Risk Localized Prostate Cancer: Efficacy, Toxicity, and Quality of Life Outcomes. Int J Radiat Oncol Biol Phys 2018;100(2):374-382.

Martin GV, Kudchadker RJ, Bruno TL, Frank SJ, Wang J. Comparison of prostate distortion by inflatable and rigid endorectal MRI coils in permanent prostate brachytherapy imaging. Brachytherapy 2018;17(2):298-305.

Blanchard P, Pugh TJ, Swanson DA, Mahmood U, Chen HC, Wang X, Graber WJ, Kudchadker RJ, Bruno T, Feeley T, Frank SJ*. Patient-reported health-related quality of life for men treated with low-dose-rate prostate brachytherapy as monotherapy with 125-iodine, 103-palladium, or 131-cesium: Results of a prospective phase II study. Brachytherapy 2018;17(2):265-276.

Blanchard P, Davis JW, Frank SJ, Kim J, Pettaway CA, Pugh TJ, Pisters LL, Ward JF, Choi S, Chapin BF, Hoffman K, Navai N, Achim M, McGuire SE, Matin SF, Nguyen Q, Mahmood U, Graber WJ, Chen HC, Wang X, Kuban DA. Quality of life after brachytherapy or bilateral nerve-sparing robot-assisted radical prostatectomy for prostate cancer: a prospective cohort. BJU Int 2018;121(4):540-548.

Sanders JW, Song H, Frank SJ, Bathala T, Venkatesan AM, Anscher M, Tang C, Bruno TL, Wei W, Ma J. Parallel imaging compressed sensing for accelerated imaging and improved signal-to-noise ratio in MRI-based postimplant dosimetry of prostate brachytherapy. Brachytherapy 2018;17(5):816-824.

Wang Li, Gagea Mihai, Martirosyan Karen, Johansen Mary, Madden Timothy, Norberg Lisa, Culotta Kirk S, Frank SJ*. Toxicity Evaluation of a Novel Magnetic Resonance Imaging Marker, CoCl2–N-Acetylcysteine, in Rats. J Toxicol 2018;2018:9173452.

Hoffman KE, Voong KR, Levy LB, Allen PK, Choi S, Schlembach PJ, Lee AK, McGuire SE, Nguyen Q, Pugh TJ, Frank SJ, Kudchadker RJ, Du W, Kuban DA. Randomized Trial of Hypofractionated, Dose-Escalated, Intensity-Modulated Radiation Therapy (IMRT) Versus Conventionally Fractionated IMRT for Localized Prostate Cancer. J Clin Oncol 2018;36(29):JCO2018779868.

Maenhout M, Peters M, Moerland MA, Meijer RP, van den Bosch MAAJ, Frank SJ, Nguyen PL, van Vulpen M, van der Voort van Zyp JRN. MRI guided focal HDR brachytherapy for localized prostate cancer: Toxicity, biochemical outcome and quality of life. Radiother Oncol 2018;129(3):554-560.

Sanders JW, Frank SJ, Kudchadker RJ, Bruno TL, Ma J. Development and clinical implementation of SeedNet: A sliding-window convolutional neural network for radioactive seed identification in MRI-assisted radiosurgery (MARS). Magn Reson Med 2019;81(6):3888-3900.

Pasalic D, Kuban DA, Allen PK, Tang C, Mesko SM, Grant SR, Augustyn AA, Frank SJ, Choi S, Hoffman KE, Nguyen QN, McGuire SE, Pollack A, Anscher MS. Dose Escalation for Prostate Adenocarcinoma: A Long-Term Update on the Outcomes of a Phase 3, Single Institution Randomized Clinical Trial. Int J Radiat Oncol Biol Phys 2019;104(4):790-797.

Ning MS, Venkatesan AM, Stafford RJ, Bui TP, Carlson R, Bailard NS, Vedam S, Davis R, Olivieri ND, Guzman AB, Incalcaterra JR, McKelvey FA, Thaker NG, Rauch GM, Tang C, Frank SJ, Joyner MM, Lin LL, Jhingran A, Eifel PJ, Klopp AH. Developing an intraoperative 3T MRI-guided brachytherapy program within a diagnostic imaging suite: Methods, process workflow, and value-based analysis. Brachytherapy 2020;19(4):427-437.

Hanania AN, Kudchadker RJ, Bruno TL, Tang C, Anscher MS, Frank SJ*. MRI-assisted radiosurgery: A quality assurance nomogram for palladium-103 and iodine-125 prostate brachytherapy. Brachytherapy 2020;19(1):38-42.

Tang C, Hoffman KE, Allen PK, Gabel M, Schreiber D, Choi S, Chapin BF, Nguyen QN, Davis JW, Corn P, Logothetis C, Ward J, Frank SJ, Navai N, McGuire SE, Anscher M, Pisters L, Pettaway CA, Kumar R, Linson P, Tripuraneni P, Tomaszewski JJ, Patel AB, Augspurger M, Kuban DA. Contemporary prostate cancer treatment choices in multidisciplinary clinics referenced to national trends. Cancer 2020;126(3):506-514.

Tang C, Lei X, Smith GL, Pan HY, Hess K, Chen A, Hoffman KE, Chapin BF, Kuban DA, Anscher M, Tina Shih YC, Frank SJ, Smith BD. Costs and Complications After a Diagnosis of Prostate Cancer Treated With Time-Efficient Modalities: An Analysis of National Medicare Data. Pract Radiat Oncol 2020;10(4):282-292.

Boyce-Fappiano D, Bathala TK, Ye R, Pasalic D, Gjyshi O, Pezzi TA, Noticewala SS, McGinnis GJ, Maroongroge S, Kuban DA, Nguyen QN, McGuire SE, Hoffman KE, Choi S, Tang C, Kudchadker RJ, Frank SJ*. Predictors of urinary toxicity with MRI-assisted radiosurgery for low-dose-rate prostate brachytherapy. Brachytherapy 2020;19(5):574-583.

Bathala TK, Venkatesan AM, Ma J, Bhosale P, Wei W, Kudchadker RJ, Wang J, Anscher MS, Tang C, Bruno TL, Frank SJ, Szklaruk J. Quality comparison between three-dimensional T2-weighted SPACE and two-dimensional T2-weighted turbo spin echo magnetic resonance images for the brachytherapy planning evaluation of prostate and periprostatic anatomy. Brachytherapy 2020;19(4):484-490.

Crook JM, Tang C, Thames H, Blanchard P, Sanders J, Ciezki J, Keyes M, Morris WJ, Merrick G, Catton C, Raziee H, Stock R, Sullivan F, Anscher M, Millar J, Frank SJ*. A biochemical definition of cure after brachytherapy for prostate cancer. Radiother Oncol 2020;149:64-69.

Abu-Gheida I, Bathala TK, Maldonado JA, Khan M, Anscher MS, Frank SJ, Choi S, Nguyen QN, Hoffman KE, McGuire SE, Kim M, Kuban DA, Aparicio A, Chapin BF, Tang C. Increased frequency of Mesorectal and Perirectal LN involvement in T4 Prostate Cancers. Int J Radiat Oncol Biol Phys 2020;107(5):982-985.

Mesko S, Chapman BV, Tang C, Kudchadker RJ, Bruno TL, Sanders J, Das P, Pinnix CC, Thaker NG, Frank SJ*. Development, implementation, and outcomes of a simulation-based medical education (SBME) prostate brachytherapy workshop for radiation oncology residents. Brachytherapy 2020;19(6):738-745.

Frank SJ, Mourtada F, Crook J, Orio PF, Stock RG, Petereit DG, Rossi PJ, Cox BW, Tang C, Kudchadker RJ, Bruno T, Ma J, Sanders J, Keyes M. The American Brachytherapy Society prostate brachytherapy LDR/HDR simulation workshops: Hands-on, step-by-step training in the process of quality assurance. Brachytherapy 2020;19(6):787-793.

Sanders JW, Lewis GD, Thames HD, Kudchadker RJ, Venkatesan AM, Bruno TL, Ma J, Pagel MD, Frank SJ*. Machine Segmentation of Pelvic Anatomy in MRI-Assisted Radiosurgery (MARS) for Prostate Cancer Brachytherapy. Int J Radiat Oncol Biol Phys 2020;108(5):1292-1303.

Sanders JW, Venkatesan AM, Levitt CA, Bathala T, Kudchadker RJ, Tang C, Bruno TL, Starks C, Santiago E, Wells M, Weaver CP, Ma J, Frank SJ*. Fully balanced SSFP without an endorectal coil for post-implant QA of MRI-assisted radiosurgery (MARS) of prostate cancer: a prospective study. Int J Radiat Oncol Biol Phys 2021;109(2):614-625.

Kamrava M, Thaker N, Small W, Frank SJ*. Driving accountable care with brachytherapy. Brachytherapy 2022; 21(1):4-5.

Thaker NG, Kudchadker RJ, Incalcaterra JR, Bathala TK, Kaplan RS, Agarwal A, Kuban DA, Frank BD, Das P, Feeley TW, Frank SJ*. Improving efficiency and reducing costs of MRI-Guided prostate brachytherapy using Time-Driven Activity-Based costing. Brachytherapy 2022; 21(1):49-54.

Sanders JW, Mok H, Hanania AN, Venkatesan AM, Tang C, Bruno TL, Thames HD, Kudchadker RJ, Frank SJ*. Computer-aided segmentation on MRI for prostate radiotherapy, Part II: Comparing human and computer observer populations and the influence of annotator variability on algorithm variability. Radiother Oncol 2022; 169:132-139.

Sanders JW, Kudchadker RJ, Tang C, Mok H, Venkatesan AM, Thames HD, Frank SJ*. Prospective Evaluation of Prostate and Organs at Risk Segmentation Software for MRI-based Prostate Radiation Therapy. Radiol Artif Intell 2022; 4(2):e210151.

Sanders JW, Frank SJ*. Erratum to: Development and clinical implementation of SeedNet: A sliding-window convolutional neural network for radioactive seed identification in MRI-assisted radiosurgery (MARS). Magn Reson Med. 2019;81:3888-3900. Magn Reson Med 2022; 87(6):3024.

Sanders JW, Tang C, Kudchadker RJ, Venkatesan AM, Mok H, Hanania AN, Thames HD, Bruno TL, Starks C, Santiago E, Cunningham M, Frank SJ*. Uncertainty in magnetic resonance imaging-based prostate postimplant dosimetry: Results of a 10-person human observer study, and comparisons with automatic postimplant dosimetry. Brachytherapy 2023; 22(6):822-832.

Tang C, Sanders J, Thames H, Swanson DM, Crook JM, Bruno T, Blanchard P, Ciezki J, Keyes M, Song D, Singh T, Merrick G, Stock R, Sullivan FJ, Mok H, Millar J, Frank SJ*. Outcomes after PD-103 versus I-125 for low dose rate prostate brachytherapy monotherapy: An international, multi-institutional study. Radiother Oncol 2023; 183:109599.

Sosa AJ, Thames HD, Sanders JW, Choi SL, Nguyen QN, Mok H, Ron Zhu X, Shah S, Mayo LL, Hoffman KE, Tang C, Lee AK, Pugh TJ, Kudchadker R, Frank SJ*. Proton therapy for the management of localized prostate cancer: Long-term clinical outcomes at a comprehensive cancer center. Radiother Oncol 2023; 188:109854.

Wang, L, Sanders, JW, Ward, JF, Lee, SR, Poenisch, F, Swanson, DM, Sahoo, N, Zhu, XR, Ma, J, Kudchadker, RJ, Choi, S, Nguyen, Q, Mayo, LL, Shah, SJ, Frank, SJ*. A Novel Polymer-Encapsulated Multi-Imaging Modality Fiducial Marker with Positive Signal Contrast for Image-Guided Radiation Therapy. Cancers 2024; 16(3).

Wang L, Ding Y, Bruno TL, Stafford RJ, Lin E, Bathala TK, Sanders JW, Ning MS, Ma J, Klopp AH, Venkatesan A, Wang J, Martirosyan KS, Frank SJ*. A Novel Positive-Contrast Magnetic Resonance Imaging Line Marker for High-Dose-Rate (HDR) MRI-Assisted Radiosurgery (MARS). Cancers (Basel) 2024; 16(10).

Orlandi E, Fontana G, Licitra L, Tinelli C, Camarda AM, Grau C, Frank SJ*. Comprehensive insights on the underlying potential and advantage of proton therapy over intensity-modulated photon radiation therapy as highlighted in a wide real world data analysis. Radiother Oncol 2024; 193:110122.

Sosa, A, Rooney, MK, Thames, HD, Sanders, JW, Swanson, DM, Choi, S, Nguyen, Q, Mok, H, Kuban, DA, Ron Zhu, X, Shah, SJ, Mayo, LL, Hoffman, K, Tang, C, McGuire, SE, Sahoo, N, Zhang, X, Lee, AK, Pugh, T, Mahmood, U, Davis, JW, Chapin, BF, Corn, P, Kudchadker, R, Ausat, N, Frank, SJ*. Proton therapy toxicity outcomes for localized prostate cancer: Long-term results at a comprehensive cancer center. Clin Transl Radiat Oncol 2024; 48.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. patent WO2012/100206 A3.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. China patent ZL200880106695.4. 2013-04-24.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. Ireland patent 2170463. 2015-03-18.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivered and Extraction Systems, and Methods of Manufacture and Use Thereof. Brazil patent BR1120130185341. 2012-01-20.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. Australia patent 2008274922. 2014-07-17.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. Canada patent 2170463. 2015-03-18.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. South Africa patent 2013/04790. 2014-12-23.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. France patent 2170463. 2015-03-18.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. Brazil patent P10813640-8 (ALLOWED). 2008-07-11.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. Canada patent 2,824,521. 2016-06-28.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. Belgium patent 2170463. 2015-03-18.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. Mexico patent 319064. 2014-04-03.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. China patent ZL201280014119.3. 2017-03-29.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. Germany patent 2170463. 2015-03-18.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. United States of America patent 8,846,006. 2014-09-30.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. South Africa patent 2010/00360. 2011-03-30.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. Australia patent 2012207142. 2017-08-10.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. United States of America patent 9,345,790. 2016-05-24.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging, European Patent Office. patent 2170463. 2015-03-18.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging, Great Britain. patent 2170463. 2015-03-18.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging, World Patent Treaty. patent PCT/US2008/06981. 2008-07-11.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. United States of America patent 8,529,872. 2013-09-10.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. Japan patent 5889337. 2016-02-26.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. Israel patent 2032329. 2014-01-07.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. Mexico patent MX/A/2013/008437.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging, Holland. patent 2170463. 2015-03-18.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. United States of America patent 9,555,135. 2017-01-31.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. Japan patent 5577245. 2014-07-11.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. Seeds and Markers for Use in Imaging. Spain patent 2170463. 2015-03-18.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. Israel patent 227576. 2016-11-01.

Frank SJ, Martirosyan K, inventors; Board of Regents, The University of Texas System, assignee. MRI Markers, Delivery and Extraction Systems, and Methods of Manufacture and Use Thereof. patent 12702692. 2012-01-20.