Selected Publications

Fusobacterium sphaericum sp. nov., isolated from a human colon tumor adheres to colonic epithelial cells and induces IL-8 secretion

Gut Microbes (2025) Opens a new window

Zepeda-Rivera MA, Eisele Y, Baryiames A, Wu H, Mengoni C, Piccinno G, McMahon EF, LaCourse KD, Jones DS, Hauner H, Minot SS, Segata N, Dewhirst FE, Johnston CD*, Bullman S*

Hemangiosarcoma Cells Promote Conserved Host-Derived Hematopoietic Expansion

Cancer Research Communications (2024) Opens a new window

Kim JH, Schulte AJ, Sarver AL, Lee D, Angelos MG, Frantz AM, Forster CL, O'Brien TD, Cornax I, O'Sullivan MG, Cheng N, Lewellen M, Oseth L, Kumar S, Bullman S, Pedamallu CS, Goyal SM, Meyerson M, Lund TC, Breen M, Lindblad-Toh K, Dickerson EB, Kaufman DS, Modiano JF

Cancer Hallmarks: Piecing the Puzzle Together

Cancer Discovery (2024) Opens a new window

Alcolea MP, Alonso-Curbelo D, Ambrogio C, Bullman S, Correia AL, Ernst A, Halbrook CJ, Kelly GL, Lund AW, Quail DF, Ruscetti M, Shema E, Stromnes IM, Tam WL

A distinct Fusobacterium nucleatum clade dominates the colorectal cancer niche

Nature (2024) Opens a new window

Zepeda-Rivera M, Minot SS, Bouzek H, Wu H, Blanco-Míguez A, Manghi P, Jones DS, LaCourse KD, Wu Y, McMahon EF, Park SN, Lim YK, Kempchinsky AG, Willis AD, Cotton SL, Yost SC, Sicinska E, Kook JK, Dewhirst FE, Segata N, Bullman S*, Johnston CD*

Bacteria-derived L-lactate fuels cervical cancer chemoradiotherapy resistance

Trends in Cancer (2024) Opens a new window

Johnston CD, Bullman S

Embracing cancer complexity: Hallmarks of systemic disease

Cell (2024) Opens a new window

Swanton C, Bernard E, Abbosh C, André F, Auwerx J, Balmain A, Bar-Sagi D, Bernards R, Bullman S, DeGregori J, Elliott C, Erez A, Evan G, Febbraio MA, Hidalgo A, Jamal-Hanjani M, Joyce JA, Kaiser M, Lamia K, Locasale JW, Loi S, Malanchi I, Merad M, Musgrave K, Patel KJ, Quezada S, Wargo JA, Weeraratna A, White E, Winkler F, Wood JN, Vousden KH, Hanahan D

The intratumoral microbiota: From microniches to single cells

Cell (2023) Opens a new window

Bullman S

INVADEseq to study the intratumoural microbiota at host single-cell resolution

Nature Reviews Cancer (2023) Opens a new window

Bullman S

INVADEseq to identify cell-adherent or invasive bacteria and the associated host transcriptome at single-cell-level resolution

Nature Protocols (2023) Opens a new window

Galeano Niño JL, Wu H, LaCourse KD, Srinivasan H, Fitzgibbon M, Minot SS, Sather C, Johnston CD*, Bullman S*

An international report on bacterial communities in esophageal squamous cell carcinoma

International Journal of Cancer (2022) Opens a new window

Nomburg J, Bullman S, Nasrollahzadeh D, Collisson EA, Abedi-Ardekani B, Akoko LO, Atkins JR, Buckle GC, Gopal S, Hu N, Kaimila B, Khoshnia M, Malekzadeh R, Menya D, Mmbaga BT, Moody S, Mulima G, Mushi BP, Mwaiselage J, Mwanga A, Newton Y, Ng DL, Radenbaugh A, Rwakatema DS, Selekwa M, Schüz J, Taylor PR, Vaske C, Goldstein A, Stratton MR, McCormack V, Brennan P, DeCaprio JA, Meyerson M, Mmbaga EJ, Van Loon K

The cancer chemotherapeutic 5-fluorouracil is a potent Fusobacterium nucleatum inhibitor and its activity is modified by intratumoral microbiota

Cell Reports (2022) Opens a new window

LaCourse KD, Zepeda-Rivera M, Kempchinsky AG, Baryiames A, Minot SS, Johnston CD*, Bullman S*

Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer

Nature (2022) Opens a new window

Galeano Niño JL, Wu H, LaCourse KD, Kempchinsky AG, Baryiames A, Barber B, Futran N, Houlton J, Sather C, Sicinska E, Taylor A, Minot SS, Johnston CD*, Bullman S*

Patients with mesenchymal tumours and high Fusobacteriales prevalence have worse prognosis in colorectal cancer (CRC)

Gut (2022) Opens a new window

Salvucci M, Crawford N, Stott K, Bullman S, Longley DB, Prehn JHM

The tumour-associated microbiome

Nature Reviews Gastroenterology & Hepatology (2022) Opens a new window

Johnston CD, Bullman S

Complete Genome Sequence of Morganella morganii CTX51T, Isolated from a Human Cecal Adenocarcinoma

Microbiology Resource Announcements (2022) Opens a new window

Stepanovica M, Zepeda-Rivera MA, McGlinchey AS, Baryiames AA, Jones DS, LaCourse KD, Bullman S, Johnston CD

Complete Genome Sequence of Clostridium cadaveris IFB3C5, Isolated from a Human Colonic Adenocarcinoma

Microbiology Resource Announcements (2022) Opens a new window

McGlinchey AS, Zepeda-Rivera MA, Stepanovica M, Baryiames AA, Jones DS, LaCourse KD, Bullman S, Johnston CD

Molecular and Pathology Features of Colorectal Tumors and Patient Outcomes Are Associated with Fusobacterium nucleatum and Its Subspecies animalis

Cancer Epidemiology, Biomarkers & Prevention (2022) Opens a new window

Borozan I, Zaidi SH, Harrison TA, Phipps AI, Zheng J, Lee S, Trinh QM, Steinfelder RS, Adams J, Banbury BL, Berndt SI, Brezina S, Buchanan DD, Bullman S, Cao Y, Farris AB 3rd, Figueiredo JC, Giannakis M, Heisler LE, Hopper JL, Lin Y, Luo X, Nishihara R, Mardis ER, Papadopoulos N, Qu C, Reid EEG, Thibodeau SN, Harlid S, Um CY, Hsu L, Gsur A, Campbell PT, Gallinger S, Newcomb PA, Ogino S, Sun W, Hudson TJ, Ferretti V, Peters U

Cancer as microenvironmental, systemic and environmental diseases: opportunity for transdisciplinary microbiomics science

Gut (2022) Opens a new window

Inamura K, Hamada T, Bullman S, Ugai T, Yachida S, Ogino S

Harnessing the microbiome to restore immunotherapy response

Nature Cancer (2021) Opens a new window

Bullman S, Eggermont A, Johnston CD, Zitvogel L

Metagenomic analysis to identify novel infectious agents in systemic anaplastic large cell lymphoma

Infectious Agents and Cancer (2021) Opens a new window

Mahale P, Nomburg J, Song JY, Steinberg M, Starrett G, Boland J, Lynch CF, Chadburn A, Rubinstein PG, Hernandez BY, Weisenburger DD, Bullman S, Engels EA

Association of Fusobacterium nucleatum with Specific T-cell Subsets in the Colorectal Carcinoma Microenvironment

Clinical Cancer Research (2021) Opens a new window

Borowsky J, Haruki K, Lau MC, Dias Costa A, Väyrynen JP, Ugai T, Arima K, da Silva A, Felt KD, Zhao M, Gurjao C, Twombly TS, Fujiyoshi K, Väyrynen SA, Hamada T, Mima K, Bullman S, Harrison TA, Phipps AI, Peters U, Ng K, Meyerhardt JA, Song M, Giovannucci EL, Wu K, Zhang X, Freeman GJ, Huttenhower C, Garrett WS, Chan AT, Leggett BA, Whitehall VLJ, Walker N, Brown I, Bettington M, Nishihara R, Fuchs CS, Lennerz JK, Giannakis M, Nowak JA, Ogino S

Characterization of Plasmacytoid Dendritic Cells, Microbial Sequences, and Identification of a Candidate Public T-Cell Clone in Kikuchi-Fujimoto Disease

Pediatric and Developmental Pathology (2021) Opens a new window

Nelson ND, Meng W, Rosenfeld AM, Bullman S, Sekhar Pedamallu C, Nomburg JL, Wertheim GB, Paessler ME, Pinkus G, Hornick JL, Meyerson M, Luning Prak ET, Pillai V

The relationship between gastrointestinal cancers and the microbiota

The Lancet Gastroenterology & Hepatology (2021) Opens a new window

LaCourse KD, Johnston CD, Bullman S

Fusobacterium nucleatum persistence and risk of recurrence after preoperative treatment in locally advanced rectal cancer.

Annals of Oncology (2020) Opens a new window

Serna G, Ruiz-Pace F, Hernando J, Alonso L, Fasani R, Landolfi S, Comas R, Jimenez J, Elez E, Bullman S, Tabernero J, Capdevila J, Dienstmann R, Nuciforo P

Association of autophagy status with amount of Fusobacterium nucleatum in colorectal cancer

The Journal of Pathology (2020) Opens a new window

Haruki K, Kosumi K, Hamada T, Twombly TS, Väyrynen JP, Kim SA, Masugi Y, Qian ZR, Mima K, Baba Y, da Silva A, Borowsky J, Arima K, Fujiyoshi K, Lau MC, Li P, Guo C, Chen Y, Song M, Nowak JA, Nishihara R, Yanaga K, Zhang X, Wu K, Bullman S, Garrett WS, Huttenhower C, Meyerhardt JA, Giannakis M, Chan AT, Fuchs CS, Ogino S

Comprehensive metagenomic analysis of blastic plasmacytoid dendritic cell neoplasm

Blood Advances (2020) Opens a new window

Nomburg J, Bullman S, Chung SS, Togami K, Walker MA, Griffin GK, Morgan EA, LeBoeuf NR, DeCaprio JA, Meyerson M, Lane AA