Areas of Research
- Brain and CNS Tumor
The Alvarez-Breckenridge laboratory is a collaborative, translational research group that focuses on metastatic disease of the brain and spine. We study the unique tumor microenvironmental features of brain and spine metastasis and primary spine tumors by analyzing the cellular composition, associated cellular interactions, and the genetic, epigenetic and transcriptional basis of tumor formation and treatment resistance. We also explore the unique features of immune cell priming and trafficking, T-cell clonal expansion, and myeloid cell regulation within both cranial and extracranial sites of disease with a view to apply our findings to develop new immunotherapeutic, clinically translational approaches to treat these tumors.
Christopher Alvarez-Breckenridge MD, PhD
MD Anderson Cancer Center
Department of Neurosurgery
1515 Holcombe Blvd.
Houston, TX 77030-4009
Contact: Stephanie Holloway firstname.lastname@example.org
Cancer Prevention & Research Institute of Texas
MD Anderson Physician Scientist Program
NIH/NINDS: K12 Neurosurgery Research Career Development Award; Research Education Grant R25
MD Anderson Cancer Center Support Grant
American Brain Tumor Association
AANS/CNS Joint Section on Tumors