James P. Allison, Ph.D.
The Allison Lab researches the fundamental mechanisms of T cell activation and regulation through cell surface receptors of the T cells and the antigen presenting cells with which they interact with. The lab also investigates the mechanisms through which alterations in cell surface receptor signaling affect the cancer immune response.
Work in the Allison lab takes advantage of the latest technology, including CyTOF and single-cell profiling of immune and cells, and collaborations with some of the world’s finest clinical oncologists at MD Anderson. The end goal of work in my lab is to provide knowledge of the immune system that serves to guide the next generation of immunotherapy, including synergistic combinations of immunotherapy with other treatment modalities to make this the last generation to know the devastation of cancer.
Meet the Team
Allison Lab, 2018 (left to right): Alex Cogdill, Nana-Ama Anang, Naveen Sharma, Stephen Mok, Xiaojie Yang, James Mancuso, Jim Allison, Tomi Atolagbe, Cecele Denman, Spencer Wei, Colm Duffy (not shown: Shirley Lindsey)