The Immunology department at MD Anderson Cancer Center seeks to determine the fundamental cellular and molecular mechanisms of a wide range of processes by which the body recognizes and eliminates pathogens and use these findings to unleash the patient’s own immune system against previously treatment-resistant cancers. Treating the immune system rather than the cancer itself, the therapeutics developed are applicable to many cancers.
Work in the department spans multiple components of the immune system, ranging from the innate immune response, by which the body recognizes defined components of common pathogens and initiates a response, to the specialized and highly regulated adaptive immune response, comprised of T cell and B cell responses. The combination of treatments that work on multiple aspects of the immune system maximizes the potential to eliminate the most treatment-resistant cancers.
Allison awarded Nobel Prize
Congratulations to our own Jim Allison, Ph.D., who was awarded the 2018 Nobel Prize in Physiology or Medicine for his pioneering work in immunotherapy.Learn more about his groundbreaking work
The Immunology department’s basic research is highly connected with cutting edge clinical care through the Immunotherapy Platform. This drives translational research that seeks to evaluate and improve immunotherapies and deliver them to the correct patient population.
The Center for Cancer Immunology Research (CCIR) is one of the six collaborative programs in biomedical research that make up the McCombs Institute for the Early Detection and Treatment of Cancer. The CCIR’s state-of-the-art facility for immunology research provides a platform for integrating basic and clinical immunology research programs.
Additionally, the Center for Inflammation and Cancer provides an interactive platform across MD Anderson and the Texas Medical Center to study cross-regulation of inflammatory cell types and tumor microenvironments and the underlying molecular mechanisms using both animal models and patient samples.
Through our commitment to research and education, we hope to train future generations of high-caliber immunologists, as well as to advance knowledge of cancer, the immune system and how to direct the immune system toward eradicating cancer.
Office of the Chair
James Mancuso, Ph.D.
Department of Immunology
The University of Texas MD Anderson Cancer Center
Immunology Department, Unit 901
P.O. Box 1301402
Houston, TX 77030-1903
Interested in learning more about immunotherapy clinical trials? Please call 1-855-873-4321 to schedule an appointment.