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Research

The Colon and Rectal Surgery department focuses on innovative approaches to the treatment of colon and rectal cancers, linking high-quality patient care, preservation of life and translational research.

Our research spans all aspects and stages of colorectal cancer, from screening and prevention to multi-disciplinary approaches for treating advanced cancers.

Research Programs

Minimally invasive surgery and enhanced recovery

The Colon and Rectal Surgery department is a world leader on innovative treatments of cancer using minimally invasive robotic and laparoscopic techniques, including for complex cancers. We utilize an Enhanced Surgical Recovery program that combines advanced minimally invasive surgery, evidence-based peri-operative care and innovations in tele-health to maximize each patient's healing. This allows our patients to proceed to the next step of treatment faster and healthier.

Topics our group is studying:

- TeleRecovery to facilitate short-stay enhanced recovery after minimally-invasive surgery for colorectal cancer
- Tele-health for patients with an ostomy
- Short and long-term clinical outcomes after robotic surgery
- Advanced minimally invasive robotic surgery for complex cancers

Advanced techniques and multi-disciplinary treatment for advanced tumors

Our group has internationally recognized expertise in the evaluation and treatment of locally advanced and recurrent cancers. Our faculty are thought leaders in advanced techniques necessary to perform high-quality surgery for complex pelvic tumors. We partner with experts across MD Anderson to ensure a thoughtful approach to difficult-to-treat tumors that will provide the best outcomes for our patients.

Topics our group is studying:

- Role of pelvic exenteration for curative management of locally advanced and recurrent rectal cancer
- Multi-disciplinary management for lateral pelvic lymph node metastasis from rectal cancer
- Quality standards for colon and rectal cancer surgery
- Impact of primary tumor resection in stage IV colorectal cancer

Organ preservation and quality of life

Our multidisciplinary experts tailor cancer therapy for each patient using advanced chemotherapy, radiotherapy and immunotherapy before surgery. The goal of such comprehensive cancer care is not only improving outcomes after surgery but maximizing the chance to preserve function and improve quality of life after surgery.

Topics our group is studying:

- Short-course and total neoadjuvant therapy for rectal cancer
- Avoiding the need for surgery (watch and wait) for rectal cancer
- Advanced surgical techniques to preserve sphincter function
- Cancer survivorship and quality of life after colorectal cancer treatment

Hereditary and young-onset colorectal cancer

The Colon and Rectal Surgery department at MD Anderson has extensive experience in the treatment of hereditary colorectal cancers and hereditary syndromes that include colorectal cancer. Young patients with colorectal cancer need specialized cancer care. This includes surveillance of possible future secondary cancers and screening of family members. We partner with the Colorectal Center Genetics Clinic to provide surveillance, prevention and genetic risk evaluation for patients with inherited or early-onset cancer.

Topics our group is studying:

- Practice guidelines for young adult-onset colorectal cancer
- Genetic factors associated with young-onset colorectal cancer
- Screening for colorectal cancer

Peritoneal carcinomatosis

The Colorectal Center at MD Anderson combines the expertise of medical oncologists, surgeons and translational researchers to study and treat peritoneal carcinomatosis (metastases within the abdominal cavity) from colorectal cancer. Our institution cares for patients with a wide spectrum of disease and provides individualized treatment plans tailored to each person's unique biology and situation.

Topics our group is studying:

- Genetics-guided treatment of colorectal cancer
- Genomics of metastatic colorectal cancer and carcinomatosis
- Outcomes following cytoreductive surgery for colorectal carcinomatosis

Translational Research

Research that translates into improved outcomes for cancer is the heart of M.D. Anderson. Our clinician-scientists work across the spectrum of
disciplines to develop innovative approaches to treat cancer from the earliest to the most advanced stages. We collaborate closely with international other leaders in the study of the basic mechanisms of cancer development and novel treatments for colorectal cancer. Translational research in the department is informed and informed by the daily clinical care of our patients to optimize outcomes now and in the future for our patients.

Topics our group is studying:

- Using next-generation sequencing and circulating tumor DNA to guide treatment decisions
- The interaction of the immune system and colorectal cancer
- The biology of colorectal cancer growth and metastatic spread
-The role of the gut and tumoral microbiome in effecting cancer development, progression, and response to therapies in local and metastatic colorectal cancer

Clinical Trials

As part of the Department of Colon & Rectal Surgery’s dedication to providing state of the art and cutting edge clinical care, we offer a number of clinical trials to our patients. The Department collaborates with other departments within the institution as well as collaborators nationally and internationally to provide these opportunities to our patients. A listing of active trials are below.

2023-0880
A phase II trial utilizing metronidazole to optimize the microbiome of rectal adenocarcinoma undergoing neoadjuvant therapy

2023-0549
Prehabpal: A digital tool to help frail elders prepare for surgery
NIH link: NCT05520866

2023-0214
A Prospective Feasibility Study Using ctDNA to Tailor Neoadjuvant Chemotherapy for Patients with Colorectal or Appendiceal Adenocarcinoma
NIH link: NCT05947838

2016-0549
Organ Preservation with AcTive Surveillance after ChemOradiation in Rectal CaNcer (OPTION)
NIH link: NCT03594630

2020-0602
SWOG S1820: A Randomized Trial of the Altering Intake, Managing Symptoms Intervention for Bowel Dysfunction in Rectal Cancer Survivors Compared to a Healthy Living Education Control: A Feasibility and Preliminary Efficacy Study (AIMS-RC)
NIH link: NCT04205955

ALLIANCE A231601CD
IMPROVING SURGICAL CARE AND OUTCOMES IN OLDER CANCER PATIENTS THROUGH IMPLEMENTATION OF AN EFFICIENT PRE-SURGICAL TOOLKIT (OPTI-SURG)
NIH link: NCT03857620

ALLIANCE A021502
Randomized Trial of Standard Chemotherapy Alone or Combined with Atezolizumab as Adjuvant Therapy for Patients with Stage III Colon Cancer and Deficient DNA Mismatch Repair
NIH link: NCT02912559

PA14-0259
Molecular Analysis of Young-Onset Colorectal Cancer

PA14-0935
PCORI Provider Survey on Treatment Eligibility

2013-0631
Prospective Evaluation of Quality of Life and Utilities Following Surgical Treatment of Rectal Cancer.
NIH link: NCT02107105

2013-0595
Quality of Life in Rectal Cancer Patients with Lynch Syndrome

PA13-0547
Facilitated Social Network for Rectal Cancer Survivors

NCCTG N1048
NCCTG N1048: A Phase II/III trial of Neoadjuvant FOLFOX, with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total M
NIH link: NCT01515787

PA11-0566
Young-onset microsatellite-stable colorectal cancer

PA11-0567
Molecular basis for variations in hereditary colorectal cancer syndromes
NIH link: NCT02863172

2010-0796
Long-Term Survivorship and Quality of Healthcare Among Adults with Colorectal Cancer

2007-0322
A Pilot Study for Prospective Discovery of Possible Relationship Between Quality of Life, Treatment Modalities, and Patient Treatment/Outcome Expectations in Patients Undergoing Treatment for Locally Recurrent Rectal Adenocarcinoma

ECOG5202
Randomized Ph III Study Comparing 5-FU, Leucovorin & Oxaliplatin vs 5-FU, Leucovorin, Oxaliplatin & Bevacizumab in Patients w/ Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively the Prognostic Value of Molecular Markers
NIH link: NCT00217737

RCR06-0400
Correlation between methods of detection of patients with hereditary nonpolyposis colorectal cancer (HNPCC)

LAB04-0962
Molecular determinants of response to preoperative therapy in patients with locally advanced colorectal cancer
NIH link: NCT02877056

Publications

2025

TreatmENT of AnastomotiC LeakagE after colon cancer resection: the TENTACLE – Colon study. Jobbe M.G. Lemmens, Sander Ubels, Nynke G. Greijdanus, Kiedo Wienholts, Marleen M.H.J. van Gelder, Albert Wolthuis, Jérémie H. Lefevre, Kilian Brown, Matteo Frasson, Nicolas Rotholtz, Quentin Denost, Rodrigo O. Perez, Tsuyoshi Konishi, Martin Rutegård, Susan L. Gearhart, Thomas Pinkney, Muhammed Elhadi, Roel Hompes, Pieter J. Tanis, Johannes H.W. de Wilt. BMC Surgery. Dec 2025 25(1) 213. doi: 10.1186/s12893-025-02954-1. PMID: 40375249. View here

Association of cancer with racial disparities in financial health: a national cohort study. J. N. Herb, C. Y. Hu, N. V. Manisundaram, G. J. Chang, R. A. Snyder. Support Care Cancer. Sep 2025 33(9) 828. doi: 10.1007/s00520-025-09881-0. PMID: 40888994. View here

Repeat Cytoreductive Surgery for Colorectal Cancer Metastatic to the Peritoneal Cavity. P. Marincola Smith, J. J. Lie, A. Seldomridge, N. J. Galbraith, J. Ramamurthy, Y. Song, B. A. Helmink, P. F. Mansfield, K. F. Fournier, M. G. White. Ann Surg Oncol. Sep 2025 () . doi: 10.1245/s10434-025-18421-3. PMID: 41015624. View here

Evaluation of Short-Term Postoperative Outcomes of Lateral Lymph Node Dissection After Neoadjuvant Radiotherapy for Rectal Cancer Patients: The Early Learning Phase After Surgical Training in the Netherlands. Eline G.M. van Geffen, Tsuyoshi Konishi, Sanne Marije J.A. Hazen, Tania C. Sluckin, Charmaine M. Tjin-A-Koeng, Eric H.J. Belgers, Johanna G. Bloemen, Esther C.J. Consten, Rogier M.P.H. Crolla, Michalda S. Dunker, Klaas Havenga, Christiaan Hoff, Fatih Polat, Maria Verseveld, Karin Horsthuis, Pieter J. Tanis, Miranda Kusters. Annals of surgical oncology. Sep 2025 32(9) 6708-6719. doi: 10.1245/s10434-025-17155-6. PMID: 40338423. View here

Association of Lateral Pelvic Lymph Nodes with Disease Recurrence and Organ Preservation in Patients with Distal Rectal Adenocarcinoma Treated with Total Neoadjuvant Therapy. Nathalie R.A. Beets, Floris S. Verheij, Hannah Williams, Dana M. Omer, Sabrina T. Lin, Li Xuan Qin, Geerard L. Beets, Regina G.H. Beets-Tan, Iris H. Wei, Maria Widmar, Emmanouil P. Pappou, Martin R. Weiser, Garrett M. Nash, J. Joshua Smith, Philip B. Paty, Joao Miranda, Tae Hyung Kim, Marc J. Gollub, Julio Garcia-Aguilar. Annals of surgery. Aug 2025 282(2) 311- 318. doi: 10.1097/SLA.0000000000006305. PMID: 38647132. View here

Enhancing Standardization in the Pediatric Management of Hereditary Polyposis Syndromes. L. Ricciardiello, Y. N. You. Cancer Prev Res (Phila). Aug 2025 () OF1-OF3. doi: 10.1158/1940-6207.CAPR-25-0279. PMID: 40843510. View here

Novel organoid culture condition: modeling fetal-like plasticity in colorectal cancer. C. Wu, M. J. Kim, J. J. Smith. Cell Res. Aug 2025 () . doi: 10.1038/s41422-025-01170-z. PMID: 40883607. View here

Idiopathic Subglottic Stenosis and the Epithelial Interface of Host and Environment. Alexander Gelbard, Meghan H. Shilts, Austin Hoke, Britton Strickland, Kevin Motz, Hsiu Wen Tsai, Helen Boone, Wonder P. Drake, Celestine Wanjalla, Paula Marincola Smith, Hunter Brown, Jason Powell, Marisol Ramirez-Solano, James B. Atkinson, John Simpson, Seesandra V. Rajagopala, Simon Mallal, Quanhu Sheng, Alexander T. Hillel, Suman R. Das. Journal of the American College of Surgeons. Aug 2025 241(2) 180-192. doi: 10.1097/XCS.0000000000001340. PMID: 39902917. View here

Addressing a common complication after ileostomy creation: a multidisciplinary program to decrease readmission for dehydration. D. Kong, S. Lin, G. Karagkounis, M. A. Abbass, M. Widmar, E. Pappou, J. J. Smith, G. M. Nash, M. R. Weiser, P. B. Paty, J. Garcia-Aguilar, I. H. Wei. Clin Surg. Aug 2025 10(1) . doi: cbi.nlm.nih.gov/40958971/. PMID: 40958971. View here

A blueprint for creating an early-onset colorectal cancer program based on experiences from 7 clinical centers across the United States and Canada. Kimmie Ng, Cathy Eng, Petra Wildgoose, Y. Nancy You, Andrea Cercek, Aparna Parikh, David Liska, Uditi Ratti, Barry D. Stein. Oncologist. Aug 2025 30(8) oyaf199. doi: 10.1093/oncolo/oyaf199. PMID: 40747803. View here

Prospective Evaluation of a Novel Unidirectional Permanent Device for Intraoperative Brachytherapy. Abraham J. Wu, Irini Youssef, Gil'ad N. Cohen, Paul B. Romesser, Neil K. Taunk, Karen Episcopia, Christopher Crane, Philip Paty, Julio Garcia-Aguilar, Martin Weiser, J. Joshua Smith, Garrett M. Nash, Eugene Cha, Aman Taggar, Zhigang Zhang, Antonio L. Damato. Advances in Radiation Oncology. Jul 2025 10(7) 101788. doi: 10.1016/j.adro.2025.101788. PMID: 40524866. View here

Robotic Surgery for Rectal Cancer - A Shift From Oncological Equivalence to Superiority. Min Jung Kim, Emmanouil P. Pappou, J. Joshua Smith. JAMA. Jul 2025 334(2) 121-123. doi: 10.1001/jama.2025.7019. PMID: 40455625. View here

ASO Author Reflections: Risk Factors for and the Oncologic Impact of Anastomotic Leakage in Mid-Low Rectal Cancer: A Long-Term Debate. K. Ochiai, T. Konishi, Surgery Japan Society of Laparoscopic Colorectal. Ann Surg Oncol. Jul 2025 () . doi: 10.1245/s10434-025-17925-2. PMID: 40739066. View here

Rethinking Local Therapy for Rectal Cancer in the Era of Precision Oncology - When Less Is More. Aron Bercz, Philip S. Bauer, J. Joshua Smith. JAMA Surgery. Jul 2025 160(7) 793-794. doi: 10.1001/jamasurg.2025.1377. PMID: 40434795. View here

Utilizing Patient Input in Rectal Cancer Trial Design. Janet Alvarez, Wini Zambare, Manju George, Reese Garcia, Phuong Gallagher, Caleah Kitchens, Aron Bercz, Min Jung Kim, Paul B. Romesser, Andrea Cercek, Julio Garcia-Aguilar, Hanna Sanoff, Thomas J. George, Theodore S. Hong, Greg Yothers, Philip A. Philip, Tareq Al Baghdadi, Olatunji B. Alese, Ardaman Shergill, Eileen M. O'Reilly, Jeffrey A. Meyerhardt, Natally Horvat, Nageshwara V. Dasari, William A. Hall, Qian Shi, Deborah Schrag, J. Joshua Smith. Journal of the National Cancer Institute. Jul 2025 117(7) 1421-1428. doi: 10.1093/jnci/djaf074. PMID: 40108482. View here

Consensus guideline for the management of gastric cancer with synchronous peritoneal metastases. Peritoneal Surface Malignancies Consortium Group, Samuel D. Butensky, Varun V. Bansal, David G. Su, Muhammad Talha Waheed, Andrei Nikiforchin, Jorge L. Gomez-Mayorga, Elizabeth Olecki, Shannon N. Radomski, Beatrice Sun, Kiran K. Turaga, Craig G. Gunderson, Jill Lacy, Brian D. Badgwell, Haejin In, Timothy Kennedy, Harry H. Yoon, Jonathan B. Greer, Raghav Sundar, Yanghee Woo, Abhineet Uppal, Adam Khader, Ahmed Hamed, Al B. Benson, Alex Fisher, Alex Kim, Alexander Loftus, Alexander S. Thomas, Alexandra Gangi, Alicia Greene, Alissa Greenbaum, Amanda Arrington, Amer K. Abu Alfa, Anai Kothari, Anand Govindarajan, Andreana N. Holowatyj, Andres Abreu, Andrew M. Bellizzi, Ankit Dhiman, Anthony Villano, Antoine Bouchard-Fortier, Anwaar Saeed, Armando Sardi, Ashley Efrain Alarcon Rozas, Avinoam Nevler, Baylee Bakkila, Benjamin Powers, Beth A. Helmink, Deyali Chatterjee, John Paul Y.C. Shen, Michael Geoffrey White. Cancer. Jul 2025 131(13) e35870. doi: 10.1002/cncr.35870. PMID: 40558029. View here

Consensus guideline for the management of colorectal cancer with peritoneal metastases. Peritoneal Surface Malignancies Consortium Group, Kurt S. Schultz, Varun V. Bansal, Michael M. Wach, Neal Bhutiani, Frederick A. Godley, Jaeyun Jane Wang, Muhammad Talha Waheed, Joanna T. Buchheit, Emily Papai, Susan Campbell, Lauren E. Schleimer, David G. Su, Kiran K. Turaga, Craig G. Gunderson, Michael Geoffrey White, Abhineet Uppal, Kanwal P.S. Raghav, Daniel M. Labow, Umut Sarpel, Ardaman P. Shergill, John Paul Y.C. Shen, Cathy Eng, Michael B. Foote, Joel M. Baumgartner. Cancer. Jul 2025 131(13) e35869. doi: 10.1002/cncr.35869. PMID: 40558054. View here

Near Complete Response: An Opportunity for Organ Preservation in Rectal Cancer. Wini Zambare, J. Joshua Smith. Annals of surgical oncology. Jul 2025 32(7) 4582-4585. doi: 10.1245/s10434-025-17310-z. PMID: 40263228. View here

Long-Term Cytoreduction Outcomes With or Without Heated Intraperitoneal Chemotherapy (HIPEC) For Colorectal Peritoneal Metastases. Michael Geoffrey White, Paula Marincola Smith, Neal Bhutiani, Beth Helmink, Norman Galbraith, Scott Kopetz, Michael Overman, Paul Mansfield, Keith Fournier, Abhineet Uppal. Journal of the American College of Surgeons. Jul 2025 241(1) 28-37. doi: 10.1097/XCS.0000000000001355. PMID: 39945444. View here

Consensus guideline for the management of patients with appendiceal tumors, part 2: Appendiceal tumors with peritoneal involvement. Peritoneal Surface Malignancies Consortium Group, Elizabeth L. Godfrey, Forest Mahoney, Varun V. Bansal, David G. Su, David N. Hanna, Felipe Lopez-Ramirez, Ekaterina Baron, Kiran K. Turaga, Al B. Benson, Namrata Setia, Joshua H. Winer, Craig G. Gunderson, Rupen Shah, Deepa R. Magge, Ian Solsky, Cathy Eng, Oliver S. Eng, Ardaman Shergill, John Paul Shen, Joseph Misdraji, Michael B. Foote, Wenyi Luo, Ahmed Hamed, Adam Khader, Alan Venook, Alda Tam, Alex Fisher, Alex Kim, Alexander Loftus, Alexander Thomas, Alexandra Gangi, Alicia Greene, Alissa Greenbaum, Amanda Arrington, Amer K. Abu Alfa, Ana Gleisner, Anai Kothari, Anand Govindarajan, Andreana N. Holowatyj, Andrei Nikiforchin, Andres Abreu, Andrew Blakely, Andrew Lowy, Andrew M. Bellizzi, Ankit Dhiman, Anthony Villano, Beth Helmink, Deyali Chatterjee, Michael White, Van Morris. Cancer. Jul 2025 131(13) e35874. doi: 10.1002/cncr.35874. PMID: 40558065. View here

The value of MRI and flexible sigmoidoscopy in detecting tumor regrowth in watch and wait rectal cancer patients undergoing active surveillance after total neoadjuvant therapy. T. M. Yeung, R. Y. Rosen, A. Bercz, H. Williams, D. Omer, F. S. Verheij, R. Behman, A. Marcadis, J. Shia, A. Cercek, N. H. Segal, R. Yaeger, T. H. Kim, N. Horvat, M. J. Gollub, J. J. Smith, L. Saltz, J. Garcia-Aguilar, Center Colorectal Cancer Disease Management Team of Memorial Sloan Kettering Cancer. Surg Endosc. Jul 2025 () . doi: 10.1007/s00464-025-11982-0. PMID: 40659952. View here

Consensus guideline for the management of patients with appendiceal tumors, part 1: Appendiceal tumors without peritoneal involvement. Peritoneal Surface Malignancies Consortium Group, Elizabeth L. Godfrey, Forest Mahoney, Varun V. Bansal, David G. Su, David N. Hanna, Felipe Lopez-Ramirez, Ekaterina Baron, Kiran K. Turaga, Al B. Benson, James Cusack, Joshua H. Winer, Craig G. Gunderson, Joseph Misdraji, Rupen Shah, Deepa R. Magge, Ian Solsky, Cathy Eng, Oliver S. Eng, Ardaman Shergill, John Paul Shen, Michael B. Foote, Ahmed Hamed, Adam Khader, Alan Venook, Alda Tam, Alex V. Fisher, Alex Kim, Alexander Loftus, Alexander Thomas, Alexandra Gangi, Alicia Greene, Alissa Greenbaum, Amanda Arrington, Amer K. Abu Alfa, Ana Gleisner, Anai Kothari, Anand Govindarajan, Andreana N. Holowatyj, Andrei Nikiforchin, Andres Abreu, Andrew Blakely, Andrew Lowy, Andrew M. Bellizzi, Ankit Dhiman, Anthony Villano, Antoine Bouchard-Fortier, Beth Helmink, Deyali Chatterjee, Michael White, Van Morris. Cancer. Jul 2025 131(13) e35867. doi: 10.1002/cncr.35867. PMID: 40560498. View here

MRI for Rectal Cancer: Updates and Controversies—AJR Expert Panel Narrative Review. Hala Khasawneh, Gaurav Khatri, Shannon P. Sheedy, Stephanie Nougaret, Doenja M.J. Lambregts, Inês Santiago, Harmeet Kaur, J. Joshua Smith, Natally Horvat. American Journal of Roentgenology. Jun 2025 224(6) e2431523. doi: 10.2214/AJR.24.31523. PMID: 39320354. View here

Does Extramural Vascular Invasion Predict Response to Neoadjuvant Therapy in Locally Advanced Rectal Cancer?. Neal Bhutiani, Mahmoud MG Yousef, Abdelrahman MG Yousef, Emaan U. Haque, George J. Chang, Tsuyoshi Konishi, Brian K. Bednarski, Y. Nancy You, John Paul Shen, Abhineet Uppal. Clinical colorectal cancer. Jun 2025 24(2) 272-279.e2. doi: 10.1016/j.clcc.2025.02.002. PMID: 40038019. View here

ASO Visual Abstract: Disparities in Survival Across Multiple Cancer Sites at Low-Income Serving Hospitals. Manisundaram NV, Hu CY, Herb JN, DiBrito SR, Snyder RA, Uppal A, Chang GJ. Ann Surg Oncol. Online ahead of print 6/18/2025. doi: 10.1245/s10434-025-17713-y. View here

Time Dependency for Human Papillomavirus Circulating Tumor DNA Detection after Chemoradiation as a Prognostic Biomarker for Localized Anal Cancer. Van K. Morris, Weihong Xiao, Kangyu Lin, Chi Wut Wong, Michael T. Wotman, Emma B. Holliday, Ryan W. Huey, Sonal S. Noticewala, Ethan B. Ludmir, Alisha H. Bent, Kaysia Ludford, Craig Messick, Eugene J. Koay, Grace Smith, Tsuyoshi Konishi, Brian Bednarski, George J. Chang, Albert C. Koong, Y. Nancy You, Prajnan Das, Maura L. Gillison. Clinical Cancer Research. Jun 2025 31(12) 2399-2405. doi: 10.1158/1078-0432.CCR-24-2575. PMID: 39873618. View here

Lack of Hierarchical Survival Prognosis in AJCC Staging for Colon and Rectal Cancer—Implications for Future Summary Stage Classification. Neal Bhutiani, Chung Yuan Hu, Bryan Palis, Joseph Cotler, Qian Shi, M. Kay Washington, Richard M. Goldberg, Scott R. Steele, George J. Chang. Clinical colorectal cancer. Jun 2025 24(2) 159-165.e2. doi: 10.1016/j.clcc.2024.11.005. PMID: 39730283. View here

Association of neighborhood socioeconomic status and ethnic diversity with receipt of adjuvant chemotherapy in stage III colon cancer: A population-based cohort study. Adom Bondzi-Simpson, Ramy Behman, Tiago Ribeiro, Sheron Perera, Aisha Lofters, Rinku Sutradhar, Vivian Aghanya, Andrea Covelli, Rebecca A. Snyder, Callisia N. Clarke, Natalie G. Coburn, Julie Hallet. Surgical Oncology Insight. Jun 2025 2(2) 100148. doi: 10.1016/j.soi.2025.100148. PMID: . View here

Clocking Recurrence: Circulating Tumor HPV DNA Kinetics in Anal Cancer. Aron Bercz, Daniel L. Faden, J. Joshua Smith, Paul B. Romesser. Clinical Cancer Research. Jun 2025 31(12) 2261-2263. doi: 10.1158/1078-0432.ccr-25-0421. PMID: 40232195. View here

Operative Strategies for Beyond Total Mesorectal Excision Surgery for Rectal Cancer. Oliver Peacock, Kilian Brown, Peadar S. Waters, John T. Jenkins, Satish K. Warrier, Alexander G. Heriot, Tamara Glyn, Frank A. Frizelle, Michael J. Solomon, Brian K. Bednarski. Annals of surgical oncology. Jun 2025 32(6) 4240-4249. doi: 10.1245/s10434-025-17151-w. PMID: 40102284. View here

Assessment of morbidity and predictors of wound complications following perineal wound closure after radical anorectal oncologic resection: Retrospective cohort study. Aron Bercz, Janet Alvarez, Roni Rosen, Matthew Drescher, Hiroyuki Sonoda, Georgios Karagkounis, Iris Wei, Maria Widmar, Garrett M. Nash, Martin R. Weiser, Philip B. Paty, Robert J. Allen, Jonas A. Nelson, Michelle Coriddi, Joseph H. Dayan, Colleen McCarthy, Farooq Shahzad, Evan Matros, Joseph J. Disa, Peter G. Cordeiro, Babak J. Mehrara, Julio Garcia-Aguilar, J. Joshua Smith, Emmanouil P. Pappou. BJS open. Jun 2025 9(3) zraf065. doi: 10.1093/bjsopen/zraf065. PMID: 40503607. View here

Impact of Patient-Reported Outcome Monitoring via Recovery Tracker on Post-Discharge Outcomes After Colorectal Surgery: A Comparative Analysis Before and After Implementation †. Hans M. Huber, Iris H. Wei, Mohammad Ali Abbass, Georgios Karagkounis, Maria Widmar, J. Joshua Smith, Garrett M. Nash, Martin R. Weiser, Philip B. Paty, Julio Garcia-Aguilar, Emmanouil Pappou. Cancers. Jun 2025 17(12) 1939. doi: 10.3390/cancers17121939. PMID: 40563589. View here

Nonoperative Management of Mismatch Repair-Deficient Tumors. Andrea Cercek, Michael B. Foote, Benoit Rousseau, J. Joshua Smith, Jinru Shia, Jenna Sinopoli, Jill Weiss, Melissa Lumish, Lindsay Temple, Miteshkumar Patel, Callahan Wilde, Leonard B. Saltz, Guillem Argiles, Zsofia Stadler, Oliver Artz, Steven Maron, Geoffrey Ku, Ping Gu, Yelena Y. Janjigian, Daniela Molena, Gopa Iyer, Jonathan Coleman, Wassim Abida, Seth Cohen, Kevin Soares, Mark Schattner, Vivian E. Strong, Rona Yaeger, Philip Paty, Marina Shcherba, Ryan Sugarman, Paul B. Romesser, Alice Zervoudakis, Avni Desai, Neil H. Segal, Imane El Dika, Maria Widmar, Iris Wei, Emmanouil Pappou, Gerard Fumo, Santiago Aparo, Mithat Gonen, Marc Gollub, Vetri S. Jayaprakasam, Tae Hyung Kim, Julio Garcia Aguilar, Martin Weiser, Luis A. Diaz. New England Journal of Medicine. Jun 2025 392(23) 2297-2308. doi: 10.1056/NEJMoa2404512. PMID: 40293177. View here

ASO Visual Abstract: Risk Factors for Regrowth After Nonoperative Management for Rectal Cancer. Neal Bhutiani, Kentaro Ochiai, Oliver Peacock, Y. Nancy You, Brian K. Bednarski, Craig Messick, John M. Skibber, Michael G. White, George J. Chang, Tsuyoshi Konishi, Abhineet Uppal. Annals of surgical oncology. Jun 2025 32(6) 4257-4258. doi: 10.1245/s10434-025-17057-7. PMID: 40202570. View here

Outcomes following diagnostic laparoscopy in patients with peritoneal carcinomatosis deemed ineligible for cytoreduction and hyperthermic intraperitoneal chemotherapy (HIPEC) due to disease burden. Paula Marincola Smith, Ashlee Seldomridge, Yi Ju Chiang, Michael G. White, Yun Song, Christopher Scally, Paul F. Mansfield, Keith F. Fournier, Beth A. Helmink. Surgical Oncology Insight. Jun 2025 2(2) 100150. doi: 10.1016/j.soi.2025.100150. PMID: 40740309. View here

Guideline-concordant treatment among adolescents and young adults with acute lymphoblastic leukemia. Julie A. Wolfson, Allison C. Grimes, Michelle M. Nuno, Subhash Ramakrishnan, David S. Dickens, Michael E. Roth, Wendy Woods, Kandice S. Adams, Tawa Alabi, Melissa Beauchemin, Jennifer M. Levine, Michele Scialla, Koh B. Boayue, Charlotte L. Kerber, Olivia Ponce, Sarah Vargas, George J. Chang, Wendy Stock, Dawn Hershman, Emily Curran, Anjali Advani, Kristen O'Dwyer, Selina Luger, Jane Jijun Liu, David R. Freyer, Lillian Sung, Susan K. Parsons. JNCI Cancer Spectrum. Jun 2025 9(3) pkaf033. doi: 10.1093/jncics/pkaf033. PMID: 40238217. View here

Appraising a CREATEive Surgeon-Scientist Initiative: Impact and Future Directions. Christopher J. Neylan, Aron Bercz, Scott E. Regenbogen, Emina H. Huang, J. Joshua Smith, Lillias H. Maguire, Jonathan B. Mitchem. Diseases of the colon and rectum. Jun 2025 68(6) 656-657. doi: 10.1097/DCR.0000000000003614. PMID: 40035458. View here

Standardization of the surgical technique and reporting for radical right colectomy with central vascular ligation and complete mesocolic excision (RRoC-STAR): Delphi consensus. Giuseppe S. Sica, Gabriele Anania, Cristina Fiorani, Leandro Siragusa, Danilo Vinci, Marco Caricato, Paolo Delrio, Antonino Agrusa, Gianandrea Baldazzi, Rossella Reddavid, Gianluca Pellino, A. Garcia-Granero, L. Ferraro, K. B. Lygre, V. Balaban, P. T. Sugoor, G. Tzovaras, W. T.L. Chen, B. S. Min, M. N.A. Tan, T. Sammour, A. Takashi, S. Benz, V. Ozben, C. Pedrazzani, G. Formisano, S. H. Kim, C. Akyol, N. West, A. M. Guida, A. Divizia, A. Giani, G. S. Banipal, I. Al-Najami, W. Luo, V. Bellato, B. M. Pirozzi, I. Seow-En, R. Bernhoff, G. Dimofte, A. M. Musina, T. Konishi, Y. S. Lee, S. Morarasu, N. Gouvas, T. Zurleni, P. Carnevali, Y. Fukunaga, M. Pramateftakis, Z. Balciscueta, M. Ali Chaouch, G. J. Chang, S. Di Carlo, I. Hamzaoglu, G. Di Buono, A. Petrov, K. Mathis, A. M. Kazaryan, M. Mazzola, S. Buscemi, E. Jovine, S. Scabini, E. Bertani, G. Ferrari, J. Khan, F. Pfeffer, G. Spinoglio, G. Luglio, G. Navarra, H. Kobayashi, S. Merkel, D. Cassini, G. N. Piozzi, M. Spalluto. BJS open. Jun 2025 9(3) zraf066. doi: 10.1093/bjsopen/zraf066. PMID: 40503608. View here

Observational survey of financial difficulties among patients with multiple myeloma and chronic lymphocytic leukaemia treated at US community oncology clinics (Alliance A231602CD). Rena M. Conti, Shaylene McCue, Travis Dockter, Heather Gunn, Stacie Dusetzina, Antonia Bennett, Bruce David Rapkin, Gabriela Gracia, Shelley A. Jazowski, Robert Behrens, Paul G. Richardson, Selina Chow, Niveditha Subbiah, Heather B. Neuman, George J. Chang, Elisa Weiss. BMJ open. Jun 2025 15(6) e091769. doi: 10.1136/bmjopen-2024-091769. PMID: 40461152. View here

Survival among patients treated with total mesorectal excision or selective watch-and-wait after total neoadjuvant therapy: a pooled analysis of the CAO/ARO/AIO-12 and OPRA randomized phase II trials. H. Williams, E. Fokas, M. Diefenhardt, C. Lee, F. S. Verheij, D. M. Omer, S. T. Lin, R. F. Dunne, J. Marcet, P. Cataldo, B. Polite, P. Piso, B. Polat, H. Dapper, M. Ghadimi, R. D. Hofheinz, L. X. Qin, L. B. Saltz, A. J. Wu, M. J. Gollub, J. J. Smith, M. R. Weiser, C. Rödel, J. Garcia-Aguilar. Annals of Oncology. May 2025 36(5) 543-547. doi: 10.1016/j.annonc.2025.01.006. PMID: 39848335. View here

ASO Visual Abstract: Evaluation of Short-Term Postoperative Outcomes of Lateral Lymph Node Dissection Post-neoadjuvant Radiotherapy in Rectal Cancer Patient-The Early Learning Phase After Surgical Training in The Netherlands. E. G. M. van Geffen, T. Konishi, S. J. A. Hazen, T. C. Sluckin, A. Koeng C. M. Tjin, E. H. J. Belgers, J. G. Bloemen, E. C. J. Consten, Rmph Crolla, M. S. Dunker, K. Havenga, C. Hoff, F. Polat, M. Verseveld, K. Horsthuis, P. J. Tanis, M. Kusters. Ann Surg Oncol. May 2025 () . doi: 10.1245/s10434-025-17230-y. PMID: 40343588. View here

Long-Term Efficacy of Pembrolizumab and the Clinical Utility of ctDNA in Locally Advanced dMMR/MSI-H Solid Tumors. Michael LaPelusa, Wei Qiao, Bryan Iorgulescu, Francis San Lucas, Keyur Patel, Deepak Bhamidipati, Jane Varkey Thomas, Nancy You, Wai Chin Foo, Dipen Maru, Selvi Thirumurthi, Van Morris, Scott Kopetz, Michael Overman, Kaysia Ludford. Nature communications. May 2025 16(1) 4514. doi: 10.1038/s41467-025-59615-3. PMID: 40374594. View here

Disparities in Survival Across Multiple Cancer Sites at Low-Income-Serving Hospitals. Naveen V. Manisundaram, Chung-Yuan Hu, Joshua N. Herb, Sandra R. DiBrito, Rebecca A Snyder, Abhineet Uppal, George J Chang. Annals of surgical oncology. May 2025 () e198577. doi: 10.1245/s10434-025-17555-8. PMID: 40450170. View here

Prospective longitudinal trajectory of cancer survivorship among patients with recurrent rectal cancer: impact of treatment modalities and resection status. Tarik Sammour, Oliver Peacock, Brian K. Bednarski, Arvind Dasari, Prajnan Das, Benny Johnson, Grace L. Smith, George J. Chang, John Skibber, Y. Nancy You. Colorectal Disease. May 2025 27(5) e70110. doi: 10.1111/codi.70110. PMID: 40371878. View here

Proceedings of the American College of Surgeons Surgical Adhesions Improvement Project Summit. The Surgical Consortium on Adhesions Research (SCAR) Advisory Group, Samuel Carmichael, David Wiseman, Deshka Foster, Eric Appel, Jessica Cardenas, Joel Zindel, Melinda Maggard-Gibbons, Richard P.G. ten Broek, Rudy Leon De Wilde, Steven Bauer, Steven Mutsaers, Tara Russell, Tess C. Huy, Timothy Donahue, Walter Koltun, Yuval Rinkevich, Clifford Y. Ko, Mark Girgis, Jorge Hernandez, Angela Bailey, Aron Bercz, Isabel Eng, David Geffen, J. Joshua Smith, Reid Christensen, Dana Andersen. Journal of the American College of Surgeons. May 2025 240(5) 812-819. doi: 10.1097/XCS.0000000000001358. PMID: 40013692. View here

Impact of Medicaid expansion on racial disparities among patients with gastrointestinal cancer. Naveen Manisundaram, Rebecca A. Snyder, Chung Yuan Hu, Sandra R. DiBrito, Joshua N. Herb, George J. Chang. Cancer. May 2025 131(9) e35879. doi: 10.1002/cncr.35879. PMID: 40267029. View here

Tumoral and circulating genomic landscape inform survival differences in colorectal carcinomatosis. Michael G. White, Reed I. Ayabe, Mohammad A. Zeineddine, Fadl A. Zeineddine, Abdelrahman M.G. Yousef, Mahmoud Yousef, Norman J. Galbraith, J.Bryan B. Iorgulescu, Christopher Scally, Keith Fournier, Timothy E. Newhook, Nancy Y. You, Jason Willis, Scott Kopetz, George J. Chang, John Paul Shen, Abhineet Uppal. Translational Oncology. May 2025 55() 102379. doi: 10.1016/j.tranon.2025.102379. PMID: 40184716. View here

Organ Preservation in Rectal Cancer: Fear of Risks Versus the Risks of Fear. Julio Garcia-Aguilar, Hannah Williams, Martin R. Weiser, J. Joshua Smith, Paul B. Romesser, Christopher Crane, Li Xuan Qin, Mithat Gonen, Andrea Cercek, Leonard B. Saltz. Journal of Clinical Oncology. May 2025 43(14) 1745-1746. doi: 10.1200/JCO-24-02723. PMID: 40080793. View here

Risk Factors for Regrowth After Nonoperative Management for Rectal Cancer. Neal Bhutiani, Kentaro Ochiai, Oliver Peacock, Y. Nancy You, Brian K. Bednarski, Craig Messick, John M. Skibber, Michael G. White, George J. Chang, Tsuyoshi Konishi, Abhineet Uppal. Annals of surgical oncology. May 2025 32(5) 3098-3105. doi: 10.1245/s10434-024-16838-w. PMID: 39924589. View here

Lessons from FOWARC: moving towards the more precise use of radiation therapy in the era of total neoadjuvant therapy. A. Bercz, W. Zambare, J. J. Smith. AME Clin Trials Rev. Apr 2025 3() . doi: 10.21037/actr-24-219. PMID: 40511302. View here

Editorial: Highlighting Repeat Diagnostic Laparoscopy After Chemotherapy in Initially Unresectable Colorectal and Appendiceal Peritoneal Metastases. Michael G. White, Oliver S. Eng. Annals of surgical oncology. Apr 2025 () . doi: 10.1245/s10434-025-17373-y. PMID: 40307518. View here

Rise in Minimally Invasive Surgery for Colorectal Cancer Is Associated with Adoption of Robotic Surgery. Naveen Manisundaram, Christopher P. Childers, Chung Yuan Hu, Abhineet Uppal, Tsuyoshi Konishi, Brian K. Bednarski, Michael G. White, Oliver Peacock, Y. Nancy You, George J. Chang. Diseases of the colon and rectum. Apr 2025 68(4) 426-436. doi: 10.1097/DCR.0000000000003617. PMID: 39745312. View here

ASO Visual Abstract: Peritoneal Cancer Index Correlates with Radiographic Assessment of Colorectal Carcinomatosis. Eleanor A. Fallon, Muhammad O. Awiwi, Neal Bhutiani, Beth Helmink, Chris P. Scally, Paul Mansfield, Keith Fournier, Raghunandan Vikram, Abhineet Uppal, Michael Geoffrey White. Annals of surgical oncology. Apr 2025 32(4) 2942. doi: 10.1245/s10434-025-16876-y. PMID: 39847285. View here

Peritoneal Cancer Index Correlates with Radiographic Assessment of Colorectal Carcinomatosis. Eleanor A. Fallon, Muhammad O. Awiwi, Neal Bhutiani, Beth Helmink, Chris P. Scally, Paul Mansfield, Keith Fournier, Raghunandan Vikram, Abhineet Uppal, Michael G. White. Annals of surgical oncology. Apr 2025 32(4) 2923-2931. doi: 10.1245/s10434-024-16737-0. PMID: 39730964. View here

ASO Author Reflections: What the Eye Cannot See. Eleanor A. Fallon, Michael G. White. Annals of surgical oncology. Apr 2025 32(4) 2938-2939. doi: 10.1245/s10434-024-16862-w. PMID: 39820784. View here

ASO Visual Abstract: Surgical Site Infections in Simultaneous Colorectal and Liver Resections for Metastatic Colorectal Adenocarcinoma. Lauren E. Schleimer, Lynn Hakki, Kenneth Seier, Susan K. Seo, Nina Cohen, Shauna Usiak, Tiffany Romero, Mini Kamboj, Crisanta Ilagan, Lily V. Saadat, Remo Alessandris, Kevin C. Soares, Jeffrey Drebin, Alice C. Wei, Maria Widmar, Iris H. Wei, J. Joshua Smith, Emmanouil P. Pappou, Philip B. Paty, Garrett M. Nash, William R. Jarnagin, Julio Garcia-Aguilar, Mithat Gonen, T. Peter Kingham, Martin R. Weiser, Michael I. D'Angelica. Annals of surgical oncology. Apr 2025 32(4) 2505-2506. doi: 10.1245/s10434-024-16689-5. PMID: 39692984. View here

Concurrent robotic colorectal surgical oncology training within a structured mentored international fellowship program. Trevor M. Yeung, Philip Bauer, Ramy Behman, Andrea Marcadis, Adam Studniarek, Garrett Nash, Julio Garcia-Aguilar. Journal of Robotic Surgery. Mar 2025 19(1) 129. doi: 10.1007/s11701-025-02287-4. PMID: 40148715. View here

Clinical and Genomic Characterization of Secondary Rectal Cancer after Radiotherapy for Prostate Cancer. Dana M. Omer, Farheen Shah, Anisha Luthra, Chin Tung Chen, Christina I. Lee, Hannah Williams, Henry Walch, Floris S. Verheij, Roni Rosen, Janet Alvarez, Canan Firat, Georgios Karagkounis, Martin R. Weiser, Maria Widmar, Iris H. Wei, Emmanouil P. Pappou, Garrett M. Nash, J. Joshua Smith, Walid K. Chatila, Paul B. Romesser, Jinru Shia, Philip B. Paty, Julio Garcia-Aguilar, Francisco Sanchez-Vega. JAMA Network Open. Online ahead of print 3/18/2025. doi: 10.1001/jamanetworkopen.2025.1039. View here

Management of Anal Dysplasia: A Pragmatic Summary of the Current Evidence and Definition of Clinical Practices for Prevention, Diagnosis, and Treatment. Marco Bertucci Zoccali, Cintia Mayumi Sakurai Kimura, Brandon C. Chapman, Tamzin Cuming, Carmen F. Fong, Naomi Jay, Jennifer A. Kaplan, Michelle J. Khan, Craig A. Messick, Vlad V. Simianu, Jeremy J. Sugrue, Luis F. Barroso. Diseases of the colon and rectum. Mar 2025 68(3) 272-286. doi: 10.1097/DCR.0000000000003444. PMID: 39641452. View here

Development and characterization of orthotopic patient-derived xenograft models of peritoneal metastatic mucinous appendiceal adenocarcinoma. I. Ito, V. K. Pattalachinti, A. M.G. Yousef, S. Chowdhury, M. M. Fanaeian, E. Haque, B. B. Gunes, M. Yousef, E. R. Salle, M. A. Zeineddine, S. Ji, R. Li, W. Wang, B. A. Helmink, M. W. Taggart, M. G. White, K. F. Fournier, N. W. Fowlkes, J. P. Shen. ESMO Gastrointestinal Oncology. Mar 2025 7() 100133. doi: 10.1016/j.esmogo.2025.100133. PMID: . View here

Correlation Between Grade of Clinical Response to Neoadjuvant Therapy for Rectal Cancer and Oncologic Outcomes in the Era of Watch-and-Wait. Roni Y. Rosen, Aron P. Bercz, Dana M. Omer, Floris S. Verheij, Hannah Williams, Parisa Malekzadeh, Danielle L. Kong, Felipe F. Quezada-Diaz, Iris H. Wei, Maria Widmar, Georgios Karagkounis, Diana Roth O'Brien, Carla Hajj, Christopher Crane, Ping Gu, Neil H. Segal, Marina Shcherba, Karuna Ganesh, Rona Yaeger, Emmanouil Pappou, Paul B. Romesser, Garrett M. Nash, Leonard B. Saltz, Andrea Cercek, Martin R. Weiser, Mithat Gönen, Philip B. Paty, Julio Garcia-Aguilar, J. Joshua Smith. Diseases of the colon and rectum. Mar 2025 68(3) 300-307. doi: 10.1097/DCR.0000000000003538. PMID: 39808079. View here

Clinical Outcomes, Patterns of Failure, and Salvage Therapies of a Large Modern Cohort of Patients With Anal Squamous Cell Carcinoma Treated With Definitive-Intent Intensity-Modulated Radiation Therapy. Diana A. Roth O'Brien, Vasilis C. Hristidis, Zakaria Chakrani, Patrick McCann, Antonio Damato, Vonetta Williams, Nicolas Cote, Marsha Reyngold, Roni Rosen, Louise Connell, Emmanouil Pappou, Carla Hajj, Philip B. Paty, Natally Horvat, Jennifer S.Golia Pernicka, Megan Fiasconaro, Jinru Shia, Jeanine Lisanti, Abraham J. Wu, Marc J. Gollub, Zhigang Zhang, Rona Yaeger, Melissa Zinovoy, Martin R. Weiser, Len Saltz, John Cuaron, Lillian Boe, Andrea Cercek, Julio Garcia-Aguilar, J. Joshua Smith, Christopher Crane, Paul B. Romesser. International Journal of Radiation Oncology Biology Physics. Mar 2025 121(4) 951-962. doi: 10.1016/j.ijrobp.2024.10.007. PMID: 39536799. View here

Integrating Tumor and Organoid DNA Methylation Profiles Reveals Robust Predictors of Chemotherapy Response in Rectal Cancer. D. Lukacsovich, W. Zambare, C. Wu, H. Huang, W. Zhang, M. J. Kim, J. Alvarez, A. Bercz, P. B. Paty, P. B. Romesser, L. Wang, J. J. Smith, X. S. Chen. medRxiv. Mar 2025 () . doi: 10.1101/2025.02.28.25322951. PMID: 40093220. View here

Factors Impacting Academic Productivity and Satisfaction of Surgeon-scientists: A Nationwide Survey. Paula Marincola Smith, Amy Martinez, Rebecca Irlmeier, Carmen C. Solórzano, Deepa Magge, Fei Ye, James R. Goldenring. Annals of surgery. Mar 2025 281(3) 445-453. doi: 10.1097/SLA.0000000000006254. PMID: 38437474. View here

Contemporary Management of Malignant Ascites. Mason A. Vierra, Ryan B. Morgan, Neal Bhutiani, Michael G. White, Oliver S. Eng. Journal of Surgical Research. Mar 2025 307() 157-175. doi: 10.1016/j.jss.2025.01.025. PMID: 40037156. View here

Rethinking the rise of early-onset gastrointestinal cancers: a call to action. Benjamin A. Weinberg, Caitlin C. Murphy, David R. Freyer, K. Leigh Greathouse, Jan K. Blancato, Elena M. Stoffel, Julia L. Drewes, Anne Blaes, John M. Salsman, Y. Nancy You, Hannah Arem, Reetu Mukherji, Priyanka Kanth, Xin Hu, Anne Fabrizio, Marion L. Hartley, Marios Giannakis, John L. Marshall. JNCI Cancer Spectrum. Feb 2025 9(1) pkaf002. doi: 10.1093/jncics/pkaf002. PMID: 39814070. View here

Mastering rectal cancer MRI: From foundational concepts to optimal staging. Carolina Augusta Modena Heming, Janet A. Alvarez, Joao Miranda, Daniel Cardoso, Caroline Lorenzoni Almeida Ghezzi, Gerda F. Nogueira, Luciana Costa-Silva, Rodrigo Sanford Damasceno, Tiago Oliveira Morita, J. Joshua Smith, Natally Horvat. European Journal of Radiology. Feb 2025 183() 111937. doi: 10.1016/j.ejrad.2025.111937. PMID: 39864243. View here

The Landscape of ctDNA in Appendiceal Adenocarcinoma. Michael Geoffrey White, Mohammad A. Zeineddine, Eleanor A. Fallon, Fadl A. Zeineddine, Julia Dansby, Saikat Chowdhury, Nicholas Hornstein, Abdelrahman Yousef, Mahmoud Yousef, Neal Bhutiani, Yue Gu, Bryan Kee, Arvind Dasari, Michael J. Overman, Kanwal Raghav, Scott Kopetz, Abhineet Uppal, Melissa Taggart, Timothy Newhook, Keith Fournier, Beth Helmink, Leylah M. Drusbosky, John Paul Y.C. Shen. Clinical Cancer Research. Feb 2025 31(3) 551-560. doi: 10.1158/1078- 0432.CCR-24-2474. PMID: 39679931. View here

Swin transformers are robust to distribution and concept drift in endoscopy-based longitudinal rectal cancer assessment. J. T. Gomez, A. Rangnekar, H. Williams, H. M. Thompson, J. Garcia-Aguilar, J. J. Smith, H. Veeraraghavan. Proc SPIE Int Soc Opt Eng. Feb 2025 13406() . doi: 10.1117/12.3046794. PMID: 41018523. View here

Surgical Site Infections in Simultaneous Colorectal and Liver Resections for Metastatic Colorectal Adenocarcinoma. Lauren E. Schleimer, Lynn Hakki, Kenneth Seier, Susan K. Seo, Nina Cohen, Shauna Usiak, Tiffany Romero, Mini Kamboj, Crisanta Ilagan, Lily V. Saadat, Remo Alessandris, Kevin C. Soares, Jeffrey Drebin, Alice C. Wei, Maria Widmar, Iris H. Wei, J. Joshua Smith, Emmanouil P. Pappou, Philip B. Paty, Garrett M. Nash, William R. Jarnagin, Julio Garcia-Aguilar, Mithat Gonen, T. Peter Kingham, Martin R. Weiser, Michael I. D'Angelica. Annals of surgical oncology. Feb 2025 32(2) 1043-1053. doi: 10.1245/s10434-024-16489-x. PMID: 39570297. View here

Evaluating a digital prehabilitation tool in patients with colorectal surgery: protocol for a multisite randomised controlled trial. Kelsey Ogomori, Jeanette Broering, Camille Rogine, Cindy Kin, George J. Chang, Emily Finlayson. BMJ open. Feb 2025 15(2) e088001. doi: 10.1136/bmjopen-2024-088001. PMID: 39965940. View here

Enhancing chemotherapy response prediction via matched colorectal tumor-organoid gene expression analysis and network-based biomarker selection. Wei Zhang, Chao Wu, Hanchen Huang, Paulina Bleu, Wini Zambare, Janet Alvarez, Lily Wang, Philip B. Paty, Paul B. Romesser, J. Joshua Smith, X. Steven Chen. Translational Oncology. Feb 2025 52() 102238. doi: 10.1016/j.tranon.2024.102238. PMID: 39754813. View here

Reply to the Letter to the Editor ‘Circulating tumor DNA after definitive therapy for locally advanced rectal cancer’ by Drs Sorscher and Rocha Lima. A. Bercz, J. J. Smith, P. B. Romesser. Annals of Oncology. Feb 2025 36(2) 224-225. doi: 10.1016/j.annonc.2024.10.826. PMID: 39658461. View here

ASO Visual Abstract: Outcomes of Distal Rectal Cancer Patients Who Did Not Qualify for Watch-and-Wait-Comparison of Intersphincteric Resection Versus Abdominoperineal Resection. Yael Feferman, Floris S. Verheij, Hannah Williams, Dana M. Omer, Emmanouil P. Pappou, Iris H. Wei, Maria Widmar, Garrett M. Nash, Philip B. Paty, J. Joshua Smith, Andrea Cercek, Rona Yaeger, Neil H. Segal, Paul B. Romesser, Christopher Crane, Leonard B. Saltz, Martin R. Weiser, Julio Garcia-Aguilar. Annals of surgical oncology. Jan 2025 32(1) 184- 185. doi: 10.1245/s10434-024-16448-6. PMID: 39496902. View here

When Benchmarks Fail Us: A Case Study in Cytoreductive Surgery. RVU Writing Group, PSM Consortium Group, Varun V. Bansal, Hunter D.D. Witmer, Christopher P. Childers, David G. Su, Kiran K. Turaga, Yanghee Woo, Xavier Keutgen, William Morano, Wilbur Bo Bowne, Vivian Strong, Vadim Gushchin, Umut Sarpel, Ugwuji Maduekwe, Travis Grotz, Trang Nguyen, Timothy Kennedy, Thinzar Lwin, TClark Gamblin, Steven Ahrendt, Stephanie Greco, Sherif Abdel-Misih, Seth Concors, Sepideh Gholami, Sean Dineen, Scott Sherman, Sanjay Bagaria, Samer Naffouje, Sameer Patel, Sam Pappas, Sabha Ganai, Ryan Merkow, Rupen Shah, Robert Sticca, Robert Barone, Richard E Royal, Richard Hoehn, Richard Berri, Richard Alexander, Rebecca Wiatrek, Ravi Chokshi, Randall Zuckerman, Prakash Pandalai, Paul Mansfield, Paul H. Sugarbaker, Patrick Wagner, Michael White, Gary N Mann, Brian Badgwell, Beth Helmink, Abhineet Uppal. Annals of surgical oncology. Jan 2025 32(1) 19-23. doi: 10.1245/s10434-024-16191-y. PMID: 39460818. View here

HIPEC for metastatic gastric cancer: Moving the needle towards 3-year survival. Neal Bhutiani, Y. David Seo, Kristen A. Robinson, Michael G. White, Naruhiko Ikoma, Paul F. Mansfield, Jenny J. Li, Mariela Blum Murphy, Jaffer A. Ajani, Brian D. Badgwell. European Journal of Surgical Oncology. Jan 2025 51(1) 108790. doi: 10.1016/j.ejso.2024.108790. PMID: 39489042. View here

Outcomes of Distal Rectal Cancer Patients Who Did Not Qualify for Watch-and-Wait: Comparison of Intersphincteric Resection Versus Abdominoperineal Resection. Yael Feferman, Floris S. Verheij, Hannah Williams, Dana M. Omer, Emmanouil P. Pappou, Iris H. Wei, Maria Widmar, Garrett M. Nash, Philip B. Paty, J. Joshua Smith, Andrea Cercek, Rona Yaeger, Neil H. Segal, Paul B. Romesser, Christopher Crane, Leonard B. Saltz, Martin R. Weiser, Julio Garcia-Aguilar. Annals of surgical oncology. Jan 2025 32(1) 128-136. doi: 10.1245/s10434-024- 16316-3. PMID: 39395915. View here

Mutational and co-mutational landscape of early onset colorectal cancer. Jumanah Yousef Alshenaifi, Guglielmo Vetere, Giulia Maddalena, Mahmoud Yousef, Michael G. White, John Paul Shen, Eduardo Vilar, Christine Parseghian, Arvind Dasari, Van Karlyle Morris, Ryan Huey, Michael J. Overman, Robert Wolff, Kanwal P. Raghav, Jason Willis, Kristin Alfaro, Andy Futreal, Y. Nancy You, Scott Kopetz. Biomarkers. 2025 30(1) 64-76. doi: 10.1080/1354750X.2024.2447089. PMID: 39761813. View here

2024

Post-treatment surveillance intensity and overall survival in prostate cancer survivors (AFT-30). Ronald C. Chen, Ramsankar Basak, Stacie Dusetzina, Deborah S. Usinger, Zahed Mohammed, Aaron D. Falchook, Jessica R. Schumacher, Amanda B. Francescatti, Amanda Cuddy, George J. Chang, Benjamin D. Kozower, Capr Greenberg. JNCI Cancer Spectrum. Dec 2024 8(6) pkae099. doi: 10.1093/jncics/pkae099. PMID: 39383199. View here

Cancer Surveillance in Solid Organ Transplant Recipients With a Pretransplant History of Malignancy: Multidisciplinary Collaborative Expert Opinion. Kymberly D. Watt, Stacey Rolak, David P. Foley, Jennifer K. Plichta, Sandhya Pruthi, Deborah Farr, Fiona O. Zwald, Richard D. Carvajal, Arkadiusz Z. Dudek, Cristina B. Sanger, Ricciardi Rocco, George J. Chang, Dizon. Transplantation. Dec 2024 108(12) 2336-2350. doi: 10.1097/TP.0000000000005056. PMID: 38771067. View here

The use of indocyanine green for lateral lymph node dissection in rectal cancer: a novel fancy tool in the armamentarium with questionable benefits. T. Konishi. Techniques in Coloproctology. Dec 2024 28(1) 96. doi: 10.1007/s10151-024-02964-w. PMID: 39134821. View here

The prognostic impact of tumor deposits in colorectal cancer: More than just N1c. Neal Bhutiani, Oliver Peacock, Abhineet Uppal, Chung Yuan Hu, Brian K. Bednarski, Melissa W. Taggart, Arvind Dasari, Van K. Morris, Harmeet Kaur, Scott Kopetz, Emma B. Holliday, Prajnan Das, Y. Nancy You, Ge Chang. Cancer. Dec 2024 130(23) 4052-4060. doi: 10.1002/cncr.35491. PMID: 39306694. View here

Reply to: Critical Appraisal of multidisciplinary treatment outcomes in young-onset colorectal cancer with synchronous liver metastases: A retrospective analysis and methodological Considerations. Harufumi Maki, Jean Nicolas Vauthey, Y. Nancy You. European Journal of Surgical Oncology. Nov 2024 50(11) 108520. doi: 10.1016/j.ejso.2024.108520. PMID: 38969532. View here

Molecular, Socioeconomic, and Clinical Factors Affecting Racial and Ethnic Disparities in Colorectal Cancer Survival. Mahmoud Yousef, Abdelrahman Yousef, Saikat Chowdhury, Mohammad M. Fanaeian, Mark Knafl, Jennifer Peterson, Mohammad Zeineddine, Kristin Alfaro, Fadl Zeineddine, Drew Goldstein, Nicholas Hornstein, Arvind Dasari, Ryan Huey, Benny Johnson, Victoria Higbie, Alisha Bent, Bryan Kee, Michael Lee, Maria Pia Morelli, Van Karlyle Morris, Daniel Halperin, Michael J. Overman, Christine Parseghian, Eduardo Vilar, Robert Wolff, Kanwal P. Raghav, Michael G. White, Abhineet Uppal, Ryan Sun, Wenyi Wang, Scott Kopetz, Jason Willis, John Paul Shen. JAMA Oncology. Nov 2024 10(11) . doi: 10.1001/jamaoncol.2024.3666. PMID: 39264607. View here

The Learning Curve for Robotic Lateral Pelvic Lymph Node Dissection for Rectal Cancer: A View from the West. Annamaria Agnes, Oliver Peacock, Naveen Manisundaram, Youngwan Kim, Nir Stanietzky, Raghunandan Vikram, Brian K. Bednarski, Y. Nancy You, Tsuyoshi Konishi, George J. Chang. Diseases of the colon and rectum. Oct 2024 67(10) 1281-1290. doi: 10.1097/DCR.0000000000003424. PMID: 38959454. View here

Improving Surgical Care and Outcomes in Older Cancer Patients Through implementation of a Pre-Surgical Toolkit (OPTI-Surg) - Final Results of a Phase III Cluster Randomized Trial (Alliance A231601CD). OPTI-Surg Investigators, George J. Chang, Heather J. Gunn, Anne K. Barber, Lisa M. Lowenstein, Daniel Dohan, Jeanette Broering, Travis Dockter, Angelina D. Tan, Amylou Dueck, Selina Chow, Heather Neuman, Emily Finlayson. Annals of surgery. Oct 2024 280(4) 623-632. doi: 10.1097/SLA.0000000000006458. PMID: 39069901. View here

Early Postoperative Prediction of Complications and Readmission after Colorectal Cancer Surgery Using an Artificial Neural Network. Annamaria Agnes, Sa Nguyen, Tsuyoshi Konishi, Oliver Peacock, Brian K. Bednarski, Nancy You, Craig Messick, Matthew Tillman, John Skibber, George J. Chang, Abhineet Uppal. Diseases of the colon and rectum. Oct 2024 67(10) 1341-1352. doi: 10.1097/DCR.0000000000003253. PMID: 38959458. View here

Optimised treatment of patients with enlarged lateral lymph nodes in rectal cancer: Protocol of an international, multicentre, prospective registration study after extensive multidisciplinary training (LaNoReC). The LaNoReC study group, Eline G.M. Van Geffen, Tania C. Sluckin, Sanne Marije J.A. Hazen, Karin Horsthuis, Martijn Intven, Susan Van Dieren, Geerard Beets, Marilyne M. Lange, Melissa W. Taggart, Regina G.H. Beets-Tan, Corrie A.M. Marijnen, Tsuyoshi Konishi, Pieter J. Tanis, Miranda Kusters, Marc R.W. Engelbrecht, Elisabeth D. Geijsen, Roel Hompes, Philip Meijnen, Jaap Stoker, Jurriaan B. Tuynman, Ingrid M. Bruijnzeel, Bas Lamme, Femke M. Alberts, Peter A. Neijenhuis, Rogier M.P.H. Crolla, Joanne Verdult, Johan H. Wijsman, Charlotte S. Van Kessel, Erik Jan Mulder, Jan Binne Hulshoff, Ivan M. Cherepanin, Hans F.J. Fabry, G. Y. Mireille The, Frank J.M. Kemper, Fatih Polat, Johanne G. Bloemen, Jacobus W.A. Burger, Jeltsje S. Cnossen, Joost Nederend, Shira H. De Bie, Robbert J.I. Bosker, Aaldert K. Talsma, Leonora S.F. Boogerd, Marc J.P.M. Govaert, Merel M. Scheurkogel, Imogeen E. Antonisse, Michail Doukas, Joost Rothbarth, Marianne De Vries, Marcel A.H. Ribbert. BMJ open. Oct 2024 14(10) e083225. doi: 10.1136/bmjopen-2023-083225. PMID: 39414276. View here

Contemporary role of the plastic and reconstructive surgeon in the outcome of female peripelvic defects after oncologic extirpation. Ashley Shin, Rami Elmorsi, Chris M. Nguyen, Donald Baumann, David M. Adelman, George J. Chang, John Skibber, Margaret S. Roubaud. Journal of surgical oncology. Oct 2024 130(5) 1119-1129. doi: 10.1002/jso.27800. PMID: 39501499. View here

Incomplete Cytoreduction and Need for Major Hepatectomy Predict Shorter Survival in Patients Undergoing Combined Cytoreductive Surgery and Hepatectomy for Metastatic Colorectal Cancer. Reed I. Ayabe, Karen Beaty, Timothy E. Newhook, Hop S.Tran Cao, Ching-Wei David Tzeng, Beth A. Helmink, Abhineet Uppal, Jean Nicolas Vauthey, Keith F. Fournier, Michael Geoffrey White. Annals of surgical oncology. Oct 2024 31(10) 6366-6368. doi: 10.1245/s10434-024-15694-y. PMID: 38971956. View here

Erratum for: Anatomic Basis of Rectal Cancer Staging: Clarifying Controversies and Misconceptions. Harmeet Kaur, Helena Gabriel, Muhammad O. Awiwi, Ekta Maheshwari, Camila Lopes Vendrami, Tsuyoshi Konishi, Melissa W. Taggart, Michael Magnetta, Linda C. Kelahan, Sonia Lee. Radiographics : a review publication of the Radiological Society of North America, Inc. Sep 2024 44(9) e249006. doi: 10.1148/rg.249006. PMID: 39231042. View here

Para-aortic Lymph Node Dissection for Colorectal Cancer: Predicting Pathologic Lymph Node Positivity and Optimizing Outcomes. Neal Bhutiani, Kentaro Ochiai, Muhammad O. Awiwi, Miguel A. Rodriguez-Bigas, Abhineet Uppal, Oliver Peacock, Craig Messick, Michael Geoffrey White, John M. Skibber, Brian K. Bednarski, Y. Nancy You, George J Chang, Harmeet Kaur, Tsuyoshi Konishi. Annals of surgical oncology. Sep 2024 31(9) 5962-5970. doi: 10.1245/s10434-024-15539-8. PMID: 38836917. View here

Estimated Financial Impact of 2021 Office-Visit Work Relative Unit Updates on Surgical Global Periods. Christopher P. Childers, Chung Yuan Hu, Stephen G. Swisher, Sandra L. Wong, George J. Chang. JAMA Surgery. Sep 2024 159(9) 1087-1089. doi: 10.1001/jamasurg.2024.2050. PMID: 38985466. View here

NCCN GUIDELINES^® INSIGHTS: Rectal Cancer, Version 3.2024 Featured Updates to the NCCN Guidelines. Al B. Benson, Alan P. Venook, Mohamed Adam, George Chang, Yi Jen Chen, Kristen K. Ciombor, Stacey A. Cohen, Harry S. Cooper, Dustin Deming, Ignacio Garrido-Laguna, Jean L. Grem, Paul Haste, J. Randolph Hecht, Hoffe. JNCCN Journal of the National Comprehensive Cancer Network. Aug 2024 22(6) 366-375. doi: 10.6004/jnccn.2024.0041. PMID: 39151454. View here

SWOG S1820: A pilot randomized trial of the Altering Intake, Managing Bowel Symptoms Intervention in Survivors of Rectal Cancer. Virginia Sun, Katherine A. Guthrie, Tracy E. Crane, Kathryn B. Arnold, Sarah Colby, Sarah G. Freylersythe, Christa Braun-Inglis, Roxanne Topacio, Craig A. Messick, Joseph C. Carmichael, Andrew A. Muskovitz, Mo Nashawaty. Cancer. Jul 2024 130(13) 2384-2394. doi: 10.1002/cncr.35264. PMID: 38386696. View here

Anatomic Basis of Rectal Cancer Staging: Clarifying Controversies and Misconceptions. Harmeet Kaur, Helena Gabriel, Muhammad O. Awiwi, Ekta Maheshwari, Camila Lopes Vendrami, Tsuyoshi Konishi, Melissa W. Taggart, Michael Magnetta, Linda C. Kelahan, Sonia Lee. Radiographics. Jul 2024 44(7) e230203. doi: 10.1148/rg.230203. PMID: 38900679. View here

Defining the subset of mutations in polymerase epsilon (POLE) associated with loss-of-proofreading (LOP) functionality. G. Maddalena, F. A. Zeineddine, S. Rivero-Hinojosa, V. N. Aushev, S. Chowdhury, M. A. Zeineddine, A. M. Yousef, T. A. Yap, A. C. EINaggar, M. C. Liu, M. White, M. J. Overman, S. Kopetz, J. P. Shen. Annals of Oncology. Jul 2024 35(7) 678- 680. doi: 10.1016/j.annonc.2024.04.009. PMID: 38734075. View here

Leveraging Nursing Assessment for Early Identification of Post Operative Gastrointestinal Dysfunction (POGD) in Patients Undergoing Colorectal Surgery. Tessy Siby, Alice Shajimon, Daniel Mullen, Shahnaz Gillani, Jeffrey R. Ong, Nikki E. Dinkins, Brittany Kruse, Carla Patel, Craig Messick, Nicole Gourmelon, Mary R. Butler, Vijaya Gottumukkala. Current Oncology. Jul 2024 31(7) 3752-3757. doi: 10.3390/curroncol31070276. PMID: 39057148. View here

Colon Cancer, Version 3.2024. Al B. Benson, Alan P. Venook, Mohamed Adam, George Chang, Yi Jen Chen, Kristen K. Ciombor, Stacey A. Cohen, Harry S. Cooper, Dustin Deming, Ignacio Garrido-Laguna, Jean L. Grem, Paul Haste, J. Randolph Hecht, Hoffe. JNCCN Journal of the National Comprehensive Cancer Network. Jun 2024 22(2d) e240029. doi: 10.6004/jnccn.2024.0029. PMID: 38862008. View here

Baseline characteristics and recruitment for SWOG S1820: altering intake, managing bowel symptoms in survivors of rectal cancer (AIMS-RC). Virginia Sun, Cynthia A. Thomson, Tracy E. Crane, Kathryn B. Arnold, Katherine A. Guthrie, Sarah G. Freylersythe, Christa Braun-Inglis, Lee Jones, Joseph C. Carmichael, Craig Messick, Devin Flaherty, Samir Ambrale, Stacey A. Cohen, Robert S. Krouse. Supportive Care in Cancer. Jun 2024 32(6) 371. doi: 10.1007/s00520-024-08527-x. PMID: 38775966. View here

Testing Machine Learning Models to Predict Postoperative Ileus after Colorectal Surgery. Garry Brydges, George J. Chang, Tong J. Gan, Tsuyoshi Konishi, Vijaya Gottumukkala, Abhineet Uppal. Current Oncology. Jun 2024 31(6) 3563-3578. doi: 10.3390/curroncol31060262. PMID: 38920745. View here

Consideration of Metastasis-Directed Therapy for Patients With Metastatic Colorectal Cancer: Expert Survey and Systematic Review. Eric D. Miller, Brett G. Klamer, Jordan M. Cloyd, Timothy M. Pawlik, Terence M. Williams, Kathryn E. Hitchcock, Paul B. Romesser, Harvey J. Mamon, Kimmie Ng, Sepideh Gholami, George J. Chang, Christopher J. Anker. Clinical colorectal cancer. Jun 2024 23(2) 160-173. doi: 10.1016/j.clcc.2024.01.004. PMID: 38365567. View here

Total Neoadjuvant Therapy for Rectal Cancer: Which Regimens to Use?. Kentaro Ochiai, Neal Bhutiani, Atsushi Ikeda, Abhineet Uppal, Michael Geoffrey White, Oliver Peacock, Craig A. Messick, Brian K. Bednarski, Yi Qian Nancy You, John M. Skibber, George J Chang, Tsuyoshi Konishi. Cancers. Jun 2024 16(11) 2093. doi: 10.3390/cancers16112093. PMID: . View here

Automated, High-Throughput Platform to Generate a High-Reliability, Comprehensive Rectal Cancer Database. Neal Bhutiani, Mahmoud M.G. Yousef, Abdelrahman Yousef, Mohammad Zeineddine, Mark Knafl, Olivia Ratliff, Uditha P. Fernando, Anastasia Turin, Fadl A. Zeineddine, Jeff Jin, Kristin Alfaro-Munoz, Drew Goldstein, George J Chang, Scott Kopetz, John Paul Y.C. Shen, Abhineet Uppal. JCO Clinical Cancer Informatics. May 2024 8() e2300219. doi: 10.1200/CCI.23.00219. PMID: 38759125. View here

Application of Machine Learning in Predicting Perioperative Outcomes in Patients with Cancer: A Narrative Review for Clinicians. Garry Brydges, Abhineet Uppal, Vijaya Gottumukkala. Current Oncology. May 2024 31(5) 2727-2747. doi: 10.3390/curroncol31050207. PMID: 38785488. View here

Multi-Institutional Study Evaluating the Role of Circulating Tumor DNA in the Management of Appendiceal Cancers. Erika Belmont, Varun V. Bansal, Mahmoud M.G. Yousef, Mohammad A. Zeineddine, David Su, Ankit Dhiman, Chih Yi Liao, Blasé Polite, Oliver S. Eng, Keith F. Fournier, Michael Geoffrey White, Kiran K. Turaga, Jo Shen. JCO Precision Oncology. May 2024 8() e2300531. doi: 10.1200/PO.23.00531. PMID: 38723230. View here

Perioperative and oncological outcomes following robotic en bloc multivisceral resection for colorectal cancer. Sandra R. DiBrito, Naveen Manisundaram, Youngwan Kim, Oliver Peacock, Chung Yuan Hu, Brian Bednarski, Y. Nancy You, Abhineet Uppal, Matthew Tillman, Tsuyoshi Konishi, Harmeet Kaur, Sarah Palmquist, Emma Holliday, D. Colorectal Disease. May 2024 26(5) 949-957. doi: 10.1111/codi.16964. PMID: 38576073. View here

Genomic Landscape of Lynch Syndrome Colorectal Neoplasia Identifies Shared Mutated Neoantigens for Immunoprevention. Ana M. Bolivar, Fahriye Duzagac, Nan Deng, Laura Reyes-Uribe, Kyle Chang, Wenhui Wu, Charles M. Bowen, Melissa W. Taggart, Selvi Thirumurthi, Patrick M. Lynch, Y. Nancy You, Jesus Rodriguez-Pascual, Steven M. Lipkin. Gastroenterology. May 2024 166(5) 787-801.e11. doi: 10.1053/j.gastro.2024.01.016. PMID: 38244726. View here

The current multidisciplinary management of rectal cancer. Neal Bhutiani, Oliver Peacock, Abhineet Uppal, Y. Nancy You, Brian K. Bednarski, John M. Skibber, Craig Messick, Michael G. White, George J. Chang, Tsuyoshi Konishi. Annals of Gastroenterological Surgery. May 2024 8(3) 394-400. doi: 10.1002/ags3.12777. PMID: . View here

Modifier 22 Use in Fee-for-Service Medicare. Christopher P. Childers, Naveen V. Manisundaram, Chung Yuan Hu, George J. Chang. JAMA Surgery. May 2024 159(5) 563-569. doi: 10.1001/jamasurg.2024.0048. PMID: 38506853. View here

The value of national accreditation program for rectal cancer: A survey of accredited programs and programs seeking accreditation. Muneera R. Kapadia, Peter J. Senatore, Craig Messick, Tracy L. Hull, Virginia O. Shaffer, Arden M. Morris, David W. Dietz, Steven D. Wexner, Elizabeth C. Wick. Surgery (United States). Apr 2024 175(4) 1007-1012. doi: 10.1016/j.surg.2023.12.005. PMID: 38267342. View here

Metastasis and the Microbiome: The Impact of Bacteria in Disseminated Colorectal Cancer. Reed I. Ayabe, Michael G. White. Frontiers in Bioscience - Landmark. Apr 2024 29(4) 12904152. doi: 10.31083/j.fbl2904152. PMID: 38682201. View here

Hepatopancreaticobiliary Resection Arginine Immunomodulation (PRIMe) trial: protocol for a randomised phase II trial of the impact of perioperative immunomodulation on immune function following resection for hepatopancreaticobiliary malignancy. Ramy Behman, Rebecca C. Auer, Lev Bubis, Grace Xu, Natalie G. Coburn, Guillaume Martel, Julie Hallet, Fady Balaa, Calvin Law, Kimberly A. Bertens, Jad Abou Khalil, Paul Jack Karanicolas. BMJ open. Apr 2024 14(4) e072159. doi: 10.1136/bmjopen-2023-072159. PMID: 38580363. View here

Immuno-Oncology: New Insights into Targets and Therapies. Shiruyeh Schokrpur, Michael G. White, Christina L. Roland, Sandip Pravin Patel. Surgical oncology clinics of North America. Apr 2024 33(2) 265-278. doi: 10.1016/j.soc.2023.12.006. PMID: 38401909. View here

Evolving survival gains in patients with young-onset colorectal cancer and synchronous resectable liver metastases. Harufumi Maki, Antony Haddad, Mateo Lendoire, Timothy E. Newhook, Oliver Peacock, Brian K. Bednarski, Tsuyoshi Konishi, Jean Nicolas Vauthey, Y. Nancy You. European Journal of Surgical Oncology. Apr 2024 50(4) 108057. doi: 10.1016/j.ejso.2024.108057. PMID: 38461567. View here

Prognostic factors of para-aortic lymph node metastasis from colorectal cancer in highly selected patients undergoing para-aortic lymph node dissection. Shin Emoto, Yosuke Fukunaga, Manabu Takamatsu, Hiroshi Kawachi, Shuhei Sano, Tetsuro Tominaga, Toshiki Mukai, Tomohiro Yamaguchi, Toshiya Nagasaki, Takashi Akiyoshi, Tsuyoshi Konishi, Satoshi Nagayama, Masashi Ueno. Surgery Today. Apr 2024 54(4) 356-366. doi: 10.1007/s00595-023-02739-0. PMID: 37648781. View here

Characteristics of Health Care Settings Where Adolescents and Young Adults Receive Care for ALL. Julie A. Wolfson, Allison C. Grimes, Michelle Nuno, Charlotte L. Kerber, Subhash Ramakrishnan, Melissa Beauchemin, David Dickens, Jennifer M. Levine, Michael E. Roth, Michele Scialla, Wendy Woods, Sarah Vargas, Boayue. JCO Oncology Practice. Apr 2024 20(4) 491-502. doi: 10.1200/OP.23.00328. PMID: 38252911. View here

Identification of colorectal cancer cell stemness from single-cell RNA sequencing. Kangyu Lin, Saikat Chowdhury, Mohammad A. Zeineddine, Fadl A. Zeineddine, Nicholas J. Hornstein, Oscar E. Villarreal, Dipen M. Maru, Cara L. Haymaker, Jean Nicolas Vauthey, George J Chang, Elena Bogatenkova, Davi Menter. Molecular Cancer Research. Apr 2024 22(4) . doi: 10.1158/1541-7786.MCR-23-0468. PMID: 38156967. View here

The empty pelvis syndrome: a core data set from the PelvEx collaborative. PelvEx Collaborative, Charles T. West, M. A. West, A. H. Mirnezami, I. Drami, T. Glyn, P. A. Sutton, J. Tiernan, C. Behrenbruch, G. Guerra, P. S. Waters, N. Woodward, S. Applin, S. J. Charles, S. A. Rose, A. Denys. British Journal of Surgery. Mar 2024 111(3) znae042. doi: 10.1093/bjs/znae042. PMID: 38456677. View here

Salvage Treatment of Recurrent or Persistent Anal Squamous Cell Carcinoma: The Role of Multi-modality Therapy. Ethan P. Damron, Jordan McDonald, Michael K. Rooney, Prajnan Das, Ethan B. Ludmir, Bruce D. Minsky, Craig Messick, George J. Chang, Van K. Morris, Emma B. Holliday. Clinical colorectal cancer. Mar 2024 23(1) 85-94. doi: 10.1016/j.clcc.2023.12.002. PMID: 38216367. View here

Lung surveillance following colorectal cancer pulmonary metastasectomy: Utilization of clinicopathologic risk factors to guide strategy. Nathaniel Deboever, Erin M. Bayley, Michael A. Eisenberg, Wayne L. Hofstetter, Reza J. Mehran, David C. Rice, Ravi Rajaram, Jack A. Roth, Boris Sepesi, Stephen G. Swisher, Ara A. Vaporciyan, Garrett L. Walsh, Brian K. Bednarski, Van K. Morris, Mara B. Antonoff. Journal of Thoracic and Cardiovascular Surgery. Mar 2024 167(3) 814-819.e2. doi: 10.1016/j.jtcvs.2023.07.017. PMID: 37495170. View here

New-onset diabetes is a predictive risk factor for pancreatic lesions in high-risk individuals: An observational cohort study. Seyda Baydogan, Chirayu Mohindroo, Merve Hasanov, Maria F. Montiel, Pompeyo Quesada, Irina M. Cazacu, Adrianna A. Luzuriaga Chavez, Maureen E. Mork, Wenli Dong, Lei Feng, Y. Nancy You, Banu Arun, Eduardo Vilar, Bro. Endoscopic Ultrasound. Mar 2024 13(2) 83-88. doi: 10.1097/eus.0000000000000057. PMID: 38947744. View here

Daily Vaginal Dilator Use During Radiation for Women With Squamous Cell Carcinoma of the Anus: Vaginal Wall Dosimetry and Patient-Reported Sexual Function. Angelica Arzola, Enoch Chang, Michael K. Rooney, Kelsey Corrigan, Prajnan Das, Ethan B. Ludmir, Eugene J. Koay, Bruce D. Minsky, Grace L. Smith, Craig Messick, Van K. Morris, Denise Nebgen, Christopher H. Crane, Emma B. Holliday. Practical radiation oncology. Mar 2024 14(2) e105-e116. doi: 10.1016/j.prro.2023.10.002. PMID: 37898354. View here

Invited Commentary. Selective lateral pelvic lymph node dissection in low rectal cancer—Planning for future directions. Tom Pampiglione, Tsuyoshi Konishi, Manish Chand. Surgery (United States). Feb 2024 175(2) 564-565. doi: 10.1016/j.surg.2023.11.003. PMID: 38052676. View here

Androgen drives melanoma invasiveness and metastatic spread by inducing tumorigenic fucosylation. Qian Liu, Emma Adhikari, Daniel K. Lester, Bin Fang, Joseph O. Johnson, Yijun Tian, Andrea T. Mockabee-Macias, Victoria Izumi, Kelly M. Guzman, Michael G. White, John M. Koomen, Jennifer A. Wargo, Jane L. Messina, Jianfei Qi, Eric K. Lau. Nature communications. Feb 2024 15(1) 1148. doi: 10.1038/s41467-024-45324-w. PMID: 38326303. View here

Serum Tumor Markers and Outcomes in Patients With Appendiceal Adenocarcinoma. Abdelrahman Yousef, Mahmoud Yousef, Mohammad A. Zeineddine, Aditya More, Mohammad Fanaeian, Saikat Chowdhury, Mark Knafl, Paul Edelkamp, Ichiaki Ito, Yue Gu, Vinay Pattalachinti, Zahra Alavi Naini, Fadl A. Zeineddine. JAMA Network Open. Feb 2024 7(2) e240260. doi: 10.1001/jamanetworkopen.2024.0260. PMID: 38416491. View here

Beating the empty pelvis syndrome: the PelvEx Collaborative core outcome set study protocol. PelvEx Collaborative, C. T. West, M. A. West, I. Drami, A. Denys, T. Glyn, P. A. Sutton, J. Tiernan, C. Behrenbruch, G. Guerra, P. S. Waters, N. Woodward, S. Applin, S. J. Charles, S. A. Rose, E. Pape, G. H. van Ramshorst, A. H. Mirnezami, A. G.J. Aalbers, N. Abdul Aziz, N. Abecasis, M. Abraham-Nordling, T. Akiyoshi, R. Alahmadi, W. Alberda, M. Albert, M. Andric, M. Angeles, E. Angenete, A. Antoniou, J. Armitage, R. Auer, K. K. Austin, E. Aytac, O. Aziz, N. Bacalbasa, R. P. Baker, M. Bali, S. Baransi, G. Baseckas, B. Bebington, M. Bedford, B. K. Bednarski, G. L. Beets, P. L. Berg, C. Bergzoll, J. Beynon, S. Biondo, K. Boyle, L. Bordeianou, G. Chang. BMJ open. Feb 2024 14(2) e076538. doi: 10.1136/bmjopen-2023-076538. PMID: 38316595. View here

Do resected colorectal cancer patients need early chest imaging? Impact of clinicopathologic characteristics on time to development of pulmonary metastases. Nathaniel Deboever, Erin M. Bayley, Michael A. Eisenberg, Wayne L. Hofstetter, Reza J. Mehran, David C. Rice, Ravi Rajaram, Jack A. Roth, Boris Sepesi, Stephen G. Swisher, Ara A. Vaporciyan, Garrett L. Walsh, Brian K. Bednarski, Van K. Morris, Mara B. Antonoff. Journal of surgical oncology. Feb 2024 129(2) 331-337. doi: 10.1002/jso.27490. PMID: 37876311. View here

Associations Between Stress, Health Behaviors, and Quality of Life in Young Couples During the Transition to Survivorship: Protocol for a Measurement Burst Study. Dalnim Cho, Michael Roth, Susan K. Peterson, Kristofer Jennings, Seokhun Kim, Shiao Pei Weathers, Sairah Ahmed, J. Andrew Livingston, Carlos Barcenas, Y. Nancy You, Kathrin Milbury. JMIR Research Protocols. Jan 2024 13(1) e53307. doi: 10.2196/53307. PMID: 38652520. View here

Repeat Cytoreduction and Hyperthermic Intraperitoneal Chemotherapy for Recurrent Mucinous Appendiceal Adenocarcinoma: A Viable Treatment Strategy with Demonstrable Benefit. Neal Bhutiani, Travis E. Grotz, Seth J. Concors, Michael G. White, Beth A. Helmink, Kanwal P. Raghav, Melissa W. Taggart, Karen A. Beaty, Richard E. Royal, Michael J. Overman, Aurelio Matamoros, Christopher P. Scally, Safia Rafeeq, Paul F. Mansfield, Keith F. Fournier. Annals of surgical oncology. Jan 2024 31(1) 614-621. doi: 10.1245/s10434-023-14422-2. PMID: 37872456. View here

2023

Validation of an endoscopic anastomotic grading score as an intraoperative method for assessing stapled rectal anastomoses. C. Farzaneh, A. Uppal, M. D. Jafari, W. Q. Duong, J. C. Carmichael, S. D. Mills, M. J. Stamos, A. Pigazzi. Techniques in Coloproctology. Dec 2023 27(12) 1235-1242. doi: 10.1007/s10151-023-02797-z. PMID: 37184769. View here

Young-onset colorectal cancer. Manon C.W. Spaander, Ann G. Zauber, Sapna Syngal, Martin J. Blaser, Joseph J. Sung, Y. Nancy You, Ernst J. Kuipers. Nature Reviews Disease Primers. Dec 2023 9(1) 21. doi: 10.1038/s41572-023-00432-7. PMID: 37105987. View here

Stoma-free survival after anastomotic leak following rectal cancer resection: worldwide cohort of 2470 patients. TENTACLE - Rectum Collaborators, Nynke G. Greijdanus, Kiedo Wienholts, Sander Ubels, Kevin Talboom, Gerjon Hannink, Albert Wolthuis, F. Borja de Lacy, Jérémie H. Lefevre, Michael Solomon, Matteo Frasson, Nicolas Rotholtz, Quentin Denost, Rodrigo O. Perez, Tsuyoshi Konishi, Yves Panis, Martin Rutegård, Roel Hompes, Camiel Rosman, Frans van Workum, Pieter J. Tanis, Johannes H.W. de Wilt, Andreas J.A. Bremers, Floris T. Ferenschild, Stefanie de Vriendt, André D'Hoore, Gabriele Bislenghi, Jordi Farguell, Antonio M. Lacy, Paula González Atienza, Charlotte S. van Kessel, Yann Parc, Thibault Voron, Maxime K. Collard, Jorge Sancho Muriel, Hannia Cholewa, Laura A. Mattioni, Alice Frontali, Sebastiaan W. Polle, Fatih Polat, Ndidi J. Obihara, Bruna B. Vailati, Miranda Kusters, Jurriaan B. Tuynmann, Sanne J.A. Hazen, Alexander A.J. Gruter, Takahiro Amano, Hajime Fujiwara, Mario Salomon, Hernan Ruiz, Ricardo Gonzalez. British Journal of Surgery. Dec 2023 110(12) 1863-1876. doi: 10.1093/bjs/znad311. PMID: 37819790. View here

Empty pelvis syndrome: PelvEx Collaborative guideline proposal. PelvicEx Collaborative, Charles T. West, C. T. West, M. A. West, A. H. Mirnezami, I. Drami, A. Denys, T. Glyn, P. A. Sutton, J. Tiernan, C. Behrenbruch, G. Guerra, P. S. Waters, N. Woodward, S. Applin, S. J. Charles, S. A. Rose, E. Pape, G. H. van Ramshorst, A. G.J. Aalbers, N. Abdul Aziz, N. Abecasis, M. Abraham-Nordling, T. Akiyoshi, R. Alahmadi, W. Alberda, M. Albert, M. Andric, M. Angeles, E. Angenete, A. Antoniou, J. Armitage, R. Auer, K. K. Austin, E. Aytac, O. Aziz, N. Bacalbasa, R. P. Baker, M. Bali, S. Baransi, G. Baseckas, B. Bebington, M. Bedford, B. K. Bednarski, G. L. Beets, P. L. Berg, C. Bergzoll, S. Biondo, K. Boyle, K. Flatmark, S. G. Larsen. British Journal of Surgery. Dec 2023 110(12) 1730-1731. doi: 10.1093/bjs/znad301. PMID: 37757457. View here

ASO Visual Abstract: Treatment Variation and Long-Term Outcomes of Low-Grade Appendiceal Neoplasms. Michael G. White, Neal Bhutiani, Beth A. Helmink, Melissa Taggart, Wai Chin Foo, Paul F. Mansfield, Keith F. Fournier, Christopher P. Scally. Annals of surgical oncology. Dec 2023 30(13) 8176. doi: 10.1245/s10434-023-13556-7. PMID: 37728822. View here

Treatment Variation and Long-Term Outcomes of Low-Grade Appendiceal Neoplasms. Michael Geoffrey White, Neal Bhutiani, Beth A. Helmink, Melissa Taggart, Wai Chin Foo, Paul F Mansfield, Keith F. Fournier, Christopher Patrick Scally. Annals of surgical oncology. Dec 2023 30(13) 8138-8143. doi: 10.1245/s10434-023-13501-8. PMID: 37702905. View here

Utility of Circulating Tumor DNA in Appendiceal Tumors. Neal Bhutiani, Beth A. Helmink, Mohammad Zeineddine, Abhineet Uppal, John Paul Shen, Erik Spickard, Michael G. White. Journal of Gastrointestinal Surgery. Dec 2023 27(12) 3071-3073. doi: 10.1007/s11605-023-05825-3. PMID: 37709990. View here

ASO Author Reflections: Contemporary Management of Low-Grade Appendiceal Mucinous Neoplasms. Michael G. White, Christopher P. Scally. Annals of surgical oncology. Dec 2023 30(13) 8168-8169. doi: 10.1245/s10434-023-13523-2. PMID: 37231292. View here

Stoma-free Survival After Rectal Cancer Resection With Anastomotic Leakage: Development and Validation of a Prediction Model in a Large International Cohort. Nynke G. Greijdanus, Kiedo Wienholts, Sander Ubels, Kevin Talboom, Gerjon Hannink, Albert Wolthuis, Francisco B. De Lacy, Jérémie H. Lefevre, Michael Solomon, Matteo Frasson, Nicolas Rotholtz, Quentin Denost, Rodrigo O. Perez, Tsuyoshi Konishi, Yves Panis, Martin Rutegård, Roel Hompes, Camiel Rosman, Frans Van Workum, Pieter J. Tanis, Johannes H.W. De Wilt. Annals of surgery. Nov 2023 278(5) 772-780. doi: 10.1097/SLA.0000000000006043. PMID: 37498208. View here

Reporting of Circumferential Resection Margin in Rectal Cancer Surgery. Naveen Manisundaram, Sandra R. DiBrito, Chung Yuan Hu, Youngwan Kim, Elizabeth Wick, Bryan Palis, Oliver Peacock, George J. Chang. JAMA Surgery. Nov 2023 158(11) 1195-1202. doi: 10.1001/jamasurg.2023.4221. PMID: 37728906. View here

Communication Frameworks for Palliative Surgical Consultations: A Randomized Study of Advanced Cancer Patients. Alisa N. Blumenthaler, Kristen Ashlee Robinson, Caitlin Hodge, Lianchun Xiao, Elizabeth J. Lilley, James F. Griffin, Michael G. White, Ryan Day, Kimberson Tanco, Eduardo Bruera, Brian D. Badgwell. Annals of surgery. Nov 2023 278(5) E1110- E1117. doi: 10.1097/SLA.0000000000005823. PMID: 36806227. View here

Decreasing Environmental Operating Room Chemotherapy Levels Following Heated Intraperitoneal Chemotherapy (HIPEC) Through Implementation of Standard Protocols. Neal Bhutiani, Michael G. White, Bradford J. Kim, Christopher P. Scally, Beth A. Helmink, Paul F. Mansfield, Keith F. Fournier, Richard E. Royal. Annals of surgical oncology. Nov 2023 30(12) 6981-6982. doi: 10.1245/s10434-023-13409-3. PMID: 37624514. View here

Endoscopic and imaging outcomes of PD-1 therapy in localised dMMR colorectal cancer. Daniel A. Fox, Deepak Bhamidipati, Tsuyoshi Konishi, Harmeet Kaur, Nancy You, Kanwal P.S. Raghav, Phillip S. Ge, Craig Messick, Benny Johnson, Van K. Morris, Jane V. Thomas, Preksha Shah, Brian K. Bednarski, Scott Kopetz, George J. Chang, Kaysia Ludford, Victoria Serpas Higbie, Michael J. Overman. European Journal of Cancer. Nov 2023 194() 113356. doi: 10.1016/j.ejca.2023.113356. PMID: 37827065. View here

Intraperitoneal Paclitaxel Is a Safe and Effective Therapeutic Strategy for Treating Mucinous Appendiceal Adenocarcinoma. Ichiaki Ito, Abdelrahman M.G. Abdelrahman, Saikat Chowdhury, Princess N. Dickson, Zahra A. Naini, Michael Geoffrey White, Karianne G. Fleten, Kjersti Flatmark, Keith F. Fournier, Natalie W. Fowlkes, John Paul Y.C. Shen. Cancer Research. Oct 2023 83(19) 3184-3191. doi: 10.1158/0008-5472.CAN-23-0013. PMID: 37433032. View here

Lessons learned from conducting the first cancer care delivery trial in the Alliance for Clinical Trials in Oncology (Alliance A191402CD). Joel E. Pacyna, Amylou C. Dueck, George J. Chang, Selina Chow, Electra D. Paskett, Simon Kim, Jon C. Tilburt. Clinical Trials. Oct 2023 20(5) 559-563. doi: 10.1177/17407745231167123. PMID: 37050880. View here

Young-onset Rectal Cancer: Unique Tumoral Microbiome and Correlation With Response to Neoadjuvant Therapy. Michael G. White, Ashish Damania, Jumanah Alshenaifi, Pranoti Sahasrabhojane, Oliver Peacock, Jillian Losh, Matthew C. Wong, Zuzana Lutter-Berkova, George J. Chang, Andrew Futreal, Jennifer A. Wargo, Nadim J. Ajami, Scott Kopetz, Y. Nancy You. Annals of surgery. Oct 2023 278(4) 538-548. doi: 10.1097/SLA.0000000000006015. PMID: 37465976. View here

ASO Visual Abstract: Hepatectomy Before Primary Tumor Resection as the Preferred Approach for Synchronous Liver Metastases from Rectal Cancer. Harufumi Maki, Reed I. Ayabe, Yujiro Nishioka, Tsuyoshi Konishi, Timothy E. Newhook, Hop S. Tran Cao, Yun Shin Chun, Ching Wei D. Tzeng, Y. Nancy You, Jean Nicolas Vauthey. Annals of surgical oncology. Sep 2023 30(9) 5403-5404. doi: 10.1245/s10434-023-13762-3. PMID: 37358681. View here

Evaluation of National Surgical Practice for Lateral Lymph Nodes in Rectal Cancer in an Untrained Setting: Time to Collaborate for Universal Consensus and Training Programs. Tsuyoshi Konishi. Annals of surgical oncology. Sep 2023 30(9) 5320-5322. doi: 10.1245/s10434-023-13540-1. PMID: 37115373. View here

ASO Author Reflections: The Patient First Approach for Synchronous Liver Metastases from Rectal Cancer. Harufumi Maki, Reed I. Ayabe, Yujiro Nishioka, Tsuyoshi Konishi, Timothy E. Newhook, Hop S. Tran Cao, Yun Shin Chun, Ching Wei D. Tzeng, Y. Nancy You, Jean Nicolas Vauthey. Annals of surgical oncology. Sep 2023 30(9) 5401-5402. doi: 10.1245/s10434-023-13767-y. PMID: 37322282. View here

Correction: Hepatectomy Before Primary Tumor Resection as Preferred Approach for Synchronous Liver Metastases from Rectal Cancer (Annals of Surgical Oncology, (2023), 30, 9, (5390- 5400), 10.1245/s10434-023-13656-4). Harufumi Maki, Reed I. Ayabe, Yujiro Nishioka, Tsuyoshi Konishi, Timothy E. Newhook, Hop S. Tran Cao, Yun Shin Chun, Ching Wei D. Tzeng, Y. Nancy You, Jean Nicolas Vauthey. Annals of surgical oncology. Sep 2023 30(9) 5405. doi: 10.1245/s10434-023-13769-w. PMID: 37344750. View here

Hepatectomy Before Primary Tumor Resection as Preferred Approach for Synchronous Liver Metastases from Rectal Cancer. Harufumi Maki, Reed I. Ayabe, Yujiro Nishioka, Tsuyoshi Konishi, Timothy E. Newhook, Hop S. Tran Cao, Yun Shin Chun, Ching Wei D. Tzeng, Y. Nancy You, Jean Nicolas Vauthey. Annals of surgical oncology. Sep 2023 30(9) 5390-5400. doi: 10.1245/s10434-023-13656-4. PMID: 37285096. View here

MDT—How it is important in rectal cancer. Brian K. Bednarski, Melissa Taggart, George J. Chang. Abdominal Radiology. Sep 2023 48(9) 2807-2813. doi: 10.1007/s00261-023- 03977-z. PMID: 37393382. View here

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Reduction of Venous Thromboembolic Disease in Colorectal Surgery. Sunil V. Patel, Sender A. Liberman, Pamela L. Burgess, Joel E. Goldberg, Vitaliy Y. Poylin, Craig A. Messick, Bradley R. Davis, Daniel L. Feingold, Amy L. Lightner, Ian M. Paquette. Diseases of the colon and rectum. Sep 2023 66(9) 1162-1173. doi: 10.1097/DCR.0000000000002975. PMID: 37318130. View here

International standardization and optimization group for intersphincteric resection (ISOG-ISR): modified Delphi consensus on anatomy, definition, indication, surgical technique, specimen description and functional outcome. Guglielmo Niccolò Piozzi, Krunal Khobragade, Vusal Aliyev, Oktar Asoglu, Paolo Pietro Bianchi, Vlad Olimpiu Butiurca, William Tzu Liang Chen, Ju Yong Cheong, Gyu Seog Choi, Andrea Coratti, Quentin Denost, Yosuke Fukunaga, Emre Gorgun, Francesco Guerra, Masaaki Ito, Jim S. Khan, Hye Jin Kim, Jin Cheon Kim, Yusuke Kinugasa, Tsuyoshi Konishi, Li Jen Kuo, Mehmet Ayhan Kuzu, Jeremie H. Lefevre, Jin Tung Liang, John Marks, Călin Molnar, Yves Panis, Philippe Rouanet, Eric Rullier, Avanish Saklani, Antonino Spinelli, Petr Tsarkov, Shunsuke Tsukamoto, Martin Weiser, Seon Hahn Kim. Colorectal Disease. Sep 2023 25(9) 1896-1909. doi: 10.1111/codi.16704. PMID: 37563772. View here

ASO Visual Abstract: Adding Induction Chemotherapy Before Chemoradiotherapy with Total Mesorectal Excision and Selective Lateral Lymph Node Dissection in Patients with Poor-Risk, Locally Advanced, Mid-to-Low Rectal Cancer May Improve Oncological Outcomes-. Tomohiro Yamaguchi, Takashi Akiyoshi, Yosuke Fukunaga, Takashi Sakamoto, Toshiki Mukai, Yukiharu Hiyoshi, Toshiya Nagasaki, Senzo Taguchi, Akiko Chino, Eiji Shinozaki, Kensei Yamaguchi, Tsuyoshi Konishi. Annals of surgical oncology. Aug 2023 30(8) 4727-4728. doi: 10.1245/s10434-023-13481-9. PMID: 37118614. View here

Adding Induction Chemotherapy Before Chemoradiotherapy with Total Mesorectal Excision and Selective Lateral Lymph Node Dissection for Patients with Poor-Risk, Locally Advanced, Mid-to-Low Rectal Cancer May Improve Oncologic Outcomes: A Propensity Score-Ma. Tomohiro Yamaguchi, Takashi Akiyoshi, Yosuke Fukunaga, Takashi Sakamoto, Toshiki Mukai, Yukiharu Hiyoshi, Toshiya Nagasaki, Senzo Taguchi, Akiko Chino, Eiji Shinozaki, Kensei Yamaguchi, Tsuyoshi Konishi. Annals of surgical oncology. Aug 2023 30(8) 4716-4724. doi: 10.1245/s10434-023-13458-8. PMID: 37032405. View here

Prognostic factors of para-aortic lymph node metastasis from colorectal cancer in highly selected patients undergoing para-aortic lymph node dissection. Shin Emoto, Yosuke Fukunaga, Manabu Takamatsu, Hiroshi Kawachi, Shuhei Sano, Tetsuro Tominaga, Toshiki Mukai, Tomohiro Yamaguchi, Toshiya Nagasaki, Takashi Akiyoshi, Tsuyoshi Konishi, Satoshi Nagayama, Masashi Ueno. Surgery Today. Online ahead of print 8/30/2023. doi: 10.1007/s00595-023-02739-0. View here

ASO Author Reflections: Oncological Outcomes of Adding Induction Chemotherapy Before Chemoradiotherapy with Total Mesorectal Excision and Selective Lateral Lymph Node Dissection in Patients with Poor-Risk, Locally Advanced Rectal Cancer. Tomohiro Yamaguchi, Takashi Akiyoshi, Tsuyoshi Konishi. Annals of surgical oncology. Aug 2023 30(8) 4725-4726. doi: 10.1245/s10434-023-13462-y. PMID: 37036587. View here

Therapeutic lateral pelvic lymph node dissection in rectal cancer: when to dissect? Size is not everything. Oliver Peacock, Naveen Manisundaram, Youngwan Kim, Tsuyoshi Konishi, Nir Stanietzky, Raghunandan Vikram, Brian K. Bednarski, Y. Nancy You, George J. Chang. British Journal of Surgery. Aug 2023 110(8) 985-986. doi: 10.1093/bjs/znad115. PMID: 37150892. View here

Patient-Reported Outcomes during and after Treatment for Locally Advanced Rectal Cancer in the PROSPECT Trial (Alliance N1048). Ethan Basch, Amylou C. Dueck, Sandra A. Mitchell, Harvey Mamon, Martin Weiser, Leonard Saltz, Marc Gollub, Lauren Rogak, Brenda Ginos, Gina L. Mazza, Brian Colgrove, George Chang, Lori Minasian, Andrea Denicoff, Gita Thanarajasingam, Benjamin Musher, Thomas George, Alan Venook, Jeffrey Farma, Eileen O'Reilly, Jeffrey A. Meyerhardt, Qian Shi, Deborah Schrag. Journal of Clinical Oncology. Jul 2023 41(21) 3724-3734. doi: 10.1200/JCO.23.00903. PMID: 37270691. View here

Patient-reported Bowel Function and Bowel-related Quality of Life After Pelvic Radiation for Rectal Adenocarcinoma: The Impact of Radiation Fractionation and Surgical Resection. Michael K. Rooney, Brian De, Kelsey Corrigan, Grace L. Smith, Cullen Taniguchi, Bruce D. Minsky, Ethan B. Ludmir, Eugene J. Koay, Prajnan Das, Albert C. Koong, Oliver Peacock, George Chang, Y. Nancy You, Van K. Morris, Graciela Nogueras-González, Emma B. Holliday. Clinical colorectal cancer. Jun 2023 22(2) 211-221. doi: 10.1016/j.clcc.2023.02.003. PMID: 36878805. View here

ASO Visual Abstract: Insurance Disparities in Access to Robotic Surgery for Colorectal Cancer. Christopher P. Childers, Abhineet Uppal, Matthew Tillman, George J. Chang, Hop S. Tran Cao. Annals of surgical oncology. Jun 2023 30(6) 3569. doi: 10.1245/s10434-023-13454-y. PMID: 37052830. View here

Insurance Disparities in Access to Robotic Surgery for Colorectal Cancer. Christopher P. Childers, Abhineet Uppal, Matthew Tillman, George J. Chang, Hop S. Tran Cao. Annals of surgical oncology. Jun 2023 30(6) 3560-3568. doi: 10.1245/s10434-023-13354-1. PMID: 36943527. View here

Efficacy of Systemic Chemotherapy in Patients With Low-grade Mucinous Appendiceal Adenocarcinoma: A Randomized Crossover Trial. John Paul Shen, Abdelrahman M. Yousef, Fadl A. Zeineddine, Mohammad A. Zeineddine, Rebecca S. Tidwell, Karen A. Beaty, Lisa C. Scofield, Safia Rafeeq, Nicholas Hornstein, Elizabeth Lano, Cathy Eng, Aurelio Matamoros, Wai Chin Foo, Abhineet Uppal, Christopher Scally, Paul Mansfield, Melissa Taggart, Kanwal P. Raghav, Michael J. Overman, Keith Fournier. JAMA Network Open. Jun 2023 6(6) e2316161. doi: 10.1001/jamanetworkopen.2023.16161. PMID: 37261831. View here

Anal Carcinoma, Version 2.2023. Al B. Benson, Alan P. Venook, Mahmoud M. Al-Hawary, Nilofer Azad, Yi Jen Chen, Kristen K. Ciombor, Stacey Cohen, Harry S. Cooper, Dustin Deming, Ignacio Garrido-Laguna, Jean L. Grem, J. Randolph Hecht, Sarah Hoffe, Joleen Hubbard, Steven Hunt, Hisham Hussan, William Jeck, Kimberly L. Johung, Nora Joseph, Natalie Kirilcuk, Smitha Krishnamurthi, Jennifer Maratt, Wells A. Messersmith, Jeffrey Meyerhardt, Eric D. Miller, Mary F. Mulcahy, Steven Nurkin, Michael J. Overman, Aparna Parikh, Hitendra Patel, Katrina Pedersen, Leonard Saltz, Charles Schneider, David Shibata, John M. Skibber, Constantinos T. Sofocleous, Eden Stotsky-Himelfarb, Anna Tavakkoli, Christopher G. Willett, Grant Williams, Frankie Algieri, Lisa Gurski, P. A.C. Katie Stehman. JNCCN Journal of the National Comprehensive Cancer Network. Jun 2023 21(6) 653-677. doi: 10.6004/jnccn.2023.0030. PMID: 37308125. View here

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Management of Fecal Incontinence. Liliana G. Bordeianou, Amy J. Thorsen, Deborah S. Keller, Alexander T. Hawkins, Craig Messick, Lucia Oliveira, Daniel L. Feingold, Amy L. Lightner, Ian M. Paquette. Diseases of the colon and rectum. May 2023 66(5) 647-661. doi: 10.1097/DCR.0000000000002776. PMID: 36799739. View here

Prospective Study of Perioperative Circulating Tumor DNA Dynamics in Patients Undergoing Hepatectomy for Colorectal Liver Metastases. Timothy E. Newhook, Michael J. Overman, Yun Shin Chun, Arvind Dasari, Ching Wei D. Tzeng, Hop S.Tran Cao, Victoria Raymond, Christine Parseghian, Benny Johnson, Yujiro Nishioka, Yoshikuni Kawaguchi, Abhineet Uppal, Timothy J. Vreeland, Ariel Jaimovich, Elsa M. Arvide, Jenilette V. Cristo, Steven H. Wei, Kanwal P. Raghav, Van K. Morris, Jeffrey E. Lee, Scott Kopetz, Jean Nicolas Vauthey. Annals of surgery. May 2023 277(5) 813-820. doi: 10.1097/SLA.0000000000005461. PMID: 35797554. View here

Germline Cancer Risk Profiles of Patients With Young-Onset Colorectal Cancer: Findings From a Prospective Universal Germline Testing and Telegenetics Program. Y. Nancy You, Julie B. Moskowitz, George J. Chang, Maureen E. Mork, Miguel A. Rodriguez-Bigas, Brian K. Bednarski, Craig A. Messick, Matthew M. Tillman, John M. Skibber, Sa T. Nguyen, Scott Kopetz, Eduardo Vilar. Diseases of the colon and rectum. Apr 2023 66(4) 531-542. doi: 10.1097/DCR.0000000000002347. PMID: 35195555. View here

Neoadjuvant Pembrolizumab in Localized Microsatellite Instability High/Deficient Mismatch Repair Solid Tumors. Kaysia Ludford, Won Jin Ho, Jane V. Thomas, Kanwal P.S. Raghav, Mariela Blum Murphy, Nicole D. Fleming, Michael S. Lee, Brandon G. Smaglo, Y. Nancy You, Matthew M. Tillman, Carlos Kamiya-Matsuoka, Selvi Thirumurthi, Craig Messick, Benny Johnson, Eduardo Vilar, Arvind Dasari, Sarah Shin, Alexei Hernandez, Xuan Yuan, Hongqui Yang, Wai Chin Foo, Wei Qiao, Dipen Maru, Scott Kopetz, Michael J. Overman. Journal of Clinical Oncology. Apr 2023 41(12) 2181-2190. doi: 10.1200/JCO.22.01351. PMID: 36623241. View here

Expert Commentary on Lateral Pelvic Sidewall Nodes. George J. Chang. Diseases of the colon and rectum. Mar 2023 66(3) 358-359. doi: 10.1097/DCR.0000000000002717. PMID: 36728390. View here

Impact of cumulative operative time on postoperative complication risk in simultaneous resections of colorectal liver metastases and primary tumors. Allison N. Martin, Ching Wei D. Tzeng, Elsa M. Arvide, John M. Skibber, George J. Chang, Yi Qian Nancy You, Brian K. Bednarski, Abhineet Uppal, Whitney L. Dewhurst, Jenilette V. Cristo, Yun S. Chun, Hop S. Tran Cao, Jean Nicolas Vauthey, Timothy E. Newhook. HPB. Mar 2023 25(3) 347-352. doi: 10.1016/j.hpb.2022.12.008. PMID: 36697350. View here

Peritoneal recurrence after resection for Stage I–III colorectal cancer: A population analysis. Taylor Aiken, Chung Yuan Hu, Abhineet Uppal, Amanda B. Francescatti, Keith F. Fournier, George J. Chang, Syed Nabeel Zafar. Journal of surgical oncology. Mar 2023 127(4) 678-687. doi: 10.1002/jso.27175. PMID: 36519668. View here

Differential Spatial Gene and Protein Expression Associated with Recurrence Following Chemoradiation for Localized Anal Squamous Cell Cancer. Sharia Hernandez, Prajnan Das, Emma B. Holliday, Li Shen, Wei Lu, Benny Johnson, Craig A. Messick, Cullen M. Taniguchi, John Skibber, Ethan B. Ludmir, Y. Nancy You, Grace Li Smith, Brian Bednarski, Larisa Kostousov, Eugene J. Koay, Bruce D. Minsky, Matthew Tillman, Shaelynn Portier, Cathy Eng, Albert C. Koong, George J. Chang, Wai Chin Foo, Jing Wang, Luisa Solis Soto, Van K. Morris. Cancers. Mar 2023 15(6) 1701. doi: 10.3390/cancers15061701. PMID: 36980587. View here

The RECOURSE Study: Long-term Oncologic Outcomes Associated With Robotically Assisted Minimally Invasive Procedures for Endometrial, Cervical, Colorectal, Lung, or Prostate Cancer: A Systematic Review and Meta-analysis. Mario M. Leitao, Usha S. Kreaden, Vincent Laudone, Bernard J. Park, Emmanouil P. Pappou, John W. Davis, David C. Rice, George J. Chang, Emma C. Rossi, April E. Hebert, April Slee, Mithat Gonen. Annals of surgery. Mar 2023 277(3) 387-396. doi: 10.1097/SLA.0000000000005698. PMID: 36073772. View here

Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines. Giulia Martina Cavestro, Alessandro Mannucci, Francesc Balaguer, Heather Hampel, Sonia S. Kupfer, Alessandro Repici, Andrea Sartore-Bianchi, Toni T. Seppälä, Vincenzo Valentini, Clement Richard Boland, Randall E. Brand, Tineke E. Buffart, Carol A. Burke, Riccardo Caccialanza, Renato Cannizzaro, Stefano Cascinu, Andrea Cercek, Emma J. Crosbie, Silvio Danese, Evelien Dekker, Maria Daca-Alvarez, Francesco Deni, Mev Dominguez- Valentin, Cathy Eng, Ajay Goel, José G. Guillem, Britt B.S.L. Houwen, Charles Kahi, Matthew F. Kalady, Fay Kastrinos, Florian Kühn, Luigi Laghi, Andrew Latchford, David Liska, Patrick Lynch, Alberto Malesci, Gianluca Mauri, Elisa Meldolesi, Pål Møller, Kevin J. Monahan, Gabriela Möslein, Caitlin C. Murphy, Karlijn Nass, Kimmie Ng, Cristina Oliani, Enrico Papaleo, Swati G. Patel, Marta Puzzono, Remo. Clinical Gastroenterology and Hepatology. Mar 2023 21(3) 581-603.e33. doi: 10.1016/j.cgh.2022.12.006. PMID: 36549470. View here

The Influence of the Microbiome on Metastatic Colorectal Cancer. Samuel Cass, Michael G. White. Clinics in Colon and Rectal Surgery. Feb 2023 36(2) 112-119. doi: 10.1055/s- 0043-1760864. PMID: 36844707. View here

Fucosylation of HLA-DRB1 regulates CD4⁺ T cell-mediated anti-melanoma immunity and enhances immunotherapy efficacy. Daniel K. Lester, Chase Burton, Alycia Gardner, Patrick Innamarato, Krithika Kodumudi, Qian Liu, Emma Adhikari, Qianqian Ming, Daniel B. Williamson, Dennie T. Frederick, Tatyana Sharova, Michael G. White, Joseph Markowitz, Biwei Cao, Jonathan Nguyen, Joseph Johnson, Matthew Beatty, Andrea Mockabee-Macias, Matthew Mercurio, Gregory Watson, Pei Ling Chen, Susan McCarthy, Carlos MoranSegura, Jane Messina, Kerry L. Thomas, Lancia Darville, Victoria Izumi, John M. Koomen, Shari A. Pilon-Thomas, Brian Ruffell, Vincent C. Luca, Robert S. Haltiwanger, Xuefeng Wang, Jennifer A. Wargo, Genevieve M. Boland, Eric K. Lau. Nature Cancer. Feb 2023 4(2) 222-239. doi: 10.1038/s43018-022-00506-7. PMID: 36690875. View here

Transcriptomic Analyses of Pretreatment Tumor Biopsy Samples, Response to Neoadjuvant Chemoradiotherapy, and Survival in Patients with Advanced Rectal Cancer. Takashi Akiyoshi, Zhe Wang, Tomoko Kaneyasu, Osamu Gotoh, Norio Tanaka, Sayuri Amino, Noriko Yamamoto, Hiroshi Kawachi, Toshiki Mukai, Yukiharu Hiyoshi, Toshiya Nagasaki, Tomohiro Yamaguchi, Tsuyoshi Konishi, Yosuke Fukunaga, Tetsuo Noda, Seiichi Mori. JAMA Network Open. Jan 2023 6(1) E2252140. doi: 10.1001/jamanetworkopen.2022.52140. PMID: 36662520. View here

Chemotherapy and Abdominal Wall Closure Technique Increase the Probability of Postoperative Ventral Incisional Hernia in Patients With Colon Cancer. David A. Santos, Liangliang Zhang, Kim Anh Do, Brian K. Bednarski, Celia Robinson Ledet, Angela Limmer, Heather Gibson, Y. Nancy You. American Surgeon. Jan 2023 89(1) 98-107. doi: 10.1177/00031348211011149. PMID: 33877925. View here

Transanal Versus Laparoscopic TME: All That Glitters is Not Gold. Montserrat Guraieb-Trueba, George J. Chang. Annals of surgery. Jan 2023 277(1) 8-Jul. doi: 10.1097/SLA.0000000000005655. PMID: 35916131. View here

Author Correction: Androgen receptor blockade promotes response to BRAF/MEK-targeted therapy (Nature, (2022), 606, 7915, (797-803), 10.1038/s41586-022-04833-8). Christopher P. Vellano, Michael G. White, Miles C. Andrews, Manoj Chelvanambi, Russell G. Witt, Joseph R. Daniele, Mark Titus, Jennifer L. McQuade, Fabio Conforti, Elizabeth M. Burton, Matthew J. Lastrapes, Gabriel Ologun, Alexandria P. Cogdill, Golnaz Morad, Peter Prieto, Alexander J. Lazar, Yanshuo Chu, Guangchun Han, M. A.Wadud Khan, Beth Helmink, Michael A. Davies, Rodabe N. Amaria, Jeffrey J. Kovacs, Scott E. Woodman, Sapna Patel, Patrick Hwu, Michael Peoples, Jeffrey E. Lee, Zachary A. Cooper, Haifeng Zhu, Guang Gao, Hiya Banerjee, Mike Lau, Jeffrey E. Gershenwald, Anthony Lucci, Emily Z. Keung, Merrick I. Ross, Laura Pala, Eleonora Pagan, Rossana Lazcano Segura, Qian Liu, Mikayla S. Borthwick, Eric Lau, Melinda S. Yates, Shannon N. Westin, Khalida Wani, Michael T. Tetzlaff, Lauren E. Haydu, Mikhila Mahendra, Xiao Yan Ma, Christopher Logothetis, Zachary Kulstad, Sarah Johnson, Courtney W. Hudgens, Ningping Feng, Lorenzo Federico, Georgina V. Long, P. Andrew Futreal, Swathi Arur, Hussein A. Tawbi, Amy E. Moran, Linghua Wang, Timothy P. Heffernan, Joseph R. Marszalek, Jennifer A. Wargo. Nature. Jan 2023 613(7945) E3. doi: 10.1038/s41586-022-05632-x. PMID: 36627494. View here

Rectal Adenocarcinoma Presenting as a Cervical Mass: A Case Report. Nir Stanietzky, Brian Bednarski, Aaron Shafer, Melissa W. Taggart, Oliver Peacock, Raghunandan Vikram. American Journal of Case Reports. 2023 24() e941884-1-e941884-6. doi: 10.12659/AJCR.941884. PMID: 38011075. View here

Preoperative Treatment of Locally Advanced Rectal Cancer. Deborah Schrag, Qian Shi, Martin R. Weiser, Marc J. Gollub, Leonard B. Saltz, Benjamin L. Musher, Joel Goldberg, Tareq Al Baghdadi, Karyn A. Goodman, Robert R. Mcwilliams, Jeffrey M. Farma, Thomas J. George, Hagen F. Kennecke, Ardaman Shergill, Michael Montemurro, Garth D. Nelson, Brian Colgrove, Vallerie Gordon, Alan P. Venook, Eileen M. O'reilly, Jeffrey A. Meyerhardt, Amylou C. Dueck, Ethan Basch, George J. Chang, Harvey J. Mamon. New England Journal of Medicine. 2023 389(4) 322-334. doi: 10.1056/NEJMoa2303269. PMID: 37272534. View here

Stranger Things: New Roles and Opportunities for Androgen Receptor in Oncology Beyond Prostate Cancer. Javier Leo, Eleonora Dondossola, Kaitlin J. Basham, Nathaniel R. Wilson, Omar Alhalabi, Jianjun Gao, Katherine C. Kurnit, Michael G. White, Jennifer L. McQuade, Shannon N. Westin, Elizabeth A. Wellberg, Daniel E. Frigo. Endocrinology. 2023 164(6) bqad071. doi: 10.1210/endocr/bqad071. PMID: 37154098. View here

Multivisceral resection for colonic splenic flexure malakoplakia: a case report of a minimally invasive approach. Andrés Ramiro Lanza Díaz, Santiago Gallardo Pezet, Osvaldo Soto González, Montserrat Guraieb Trueba, Ivan Azael Martínez Alonso, Mario Alberto L. Ramirez. Annals of Coloproctology. 2023 39(2) 178-182. doi: 10.3393/ac.2021.00178.0025. PMID: 34284559. View here

Colorectal surveillance outcomes from an institutional longitudinal cohort of lynch syndrome carriers. Gabriel del Carmen, Laura Reyes-Uribe, Daniel Goyco, Kyera Evans, Charles M. Bowen, Jennifer L. Kinnison, Valerie O. Sepeda, Diane M. Weber, Julie Moskowitz, Maureen E. Mork, Selvi Thirumurthi, Patrick M. Lynch, Miguel A. Rodriguez-Bigas, Melissa W. Taggart, Y. Nancy You, Eduardo Vilar. Frontiers in Oncology. 2023 13() 1146825. doi: 10.3389/fonc.2023.1146825. PMID: 37168379. View here

HPV-related anal cancer is associated with changes in the anorectal microbiome during cancer development. Jacob H. Elnaggar, Victoria O. Huynh, Daniel Lin, R. Tyler Hillman, Chike O. Abana, Molly B. El Alam, Katarina C. Tomasic, Tatiana V. Karpinets, Ramez Kouzy, Jae L. Phan, Jennifer Wargo, Emma B. Holliday, Prajnan Das, Melissa P. Mezzari, Nadim J. Ajami, Erica J. Lynn, Bruce D. Minsky, Van K. Morris, Andrea Milbourne, Craig A. Messick, Ann H. Klopp, P. Andrew Futreal, Cullen M. Taniguchi, Kathleen M. Schmeler, Lauren E. Colbert. Frontiers in immunology. 2023 14() 1051431. doi: 10.3389/fimmu.2023.1051431. PMID: 37063829. View here

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