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Myeloproliferative Disorder Treatment

As one of the world’s most active centers for the care of myeloproliferative disorder, MD Anderson has a level of experience and expertise that can make a profound difference in your treatment. Our experts design your personal care plan specifically for you, drawing upon the most advanced options with the least impact on your body.

We are at the forefront of developing new treatments for MPD, including innovative drugs to improve blood counts. As one of the nation’s leading MPD research programs, we are able to offer clinical trials of investigational agents, while most other cancer centers do not.

Myeloproliferative Disorder Treatments

Myeloproliferative disorder is often challenging to treat, and it may require years of therapy and follow-up care. Treatments for MPD generally are aimed at controlling disease symptoms, and your symptoms will help the doctor decide which treatment is best. Therapies may include one or more of the following.

  • Medications: Aspirin, hydroxyurea, anagrelide and interferon-alpha are the main medications for essential thrombocytemia and polycythemia vera. Thalidomide, steroids and other hormones, and cladribine and busulfan also may be used.
  • Blood or platelet transfusion 
  • Growth factors, which stimulate growth of bone marrow cells, are given as injections under the skin and may benefit patients with low blood cell counts.
  • Radiation therapy
  • Surgical removal of the spleen
  • Phlebotomy

Treatment at MD Anderson

Myeloproliferative disorders are treated in our Leukemia Center.

Clinical Trials

MD Anderson patients have access to clinical trials offering promising new treatments that cannot be found anywhere else.

Knowledge Center

Find the latest news and information about myeloproliferative disorder in our Knowledge Center, including blog posts, articles, videos, news releases and more.


MD Anderson has licensed social workers to help patients and their loved ones cope with cancer.


Talk to someone who shares your cancer diagnosis and be matched with a survivor.

Prevention and Screening

Many cancers can be prevented with lifestyle changes and regular screening.